{"title":"ANTIFUNGAL ACTIVITY AND STAINING PROPERTIES OF SOME SYMMETRICALLY FUNCTIONALIZED METAL PHTHALOCYANINE DYES","authors":"M. P. Somashekarappa, J. Keshavayya","doi":"10.55218/jasr.202213911","DOIUrl":"https://doi.org/10.55218/jasr.202213911","url":null,"abstract":"Effects of 1, 8, 15, 22-tetranitro Co(II) and Zn(II) phthalocyanines [3-NO2CoPc, 3-NO2ZnPc], 1,8,15,22-tetracyano Co(II) phthalocyanine [3-CNCoPc] and 2, 9, 16, 23-tetranitro iron(III)chlorophthalocyanine [4-NO2FePc] on the growth of the fungus Aspergillus niger were studied. All the four complexes inhibited the radial spread of the fungus selected for the study to different extents. A considerable inhibitory effect on growth was seen even in l ppm concentration. The order of inhibitory effect, measured for a period of 5 days is 3-NO2 ZnPc > 3-CNCoPc > 3-NO2CoPc > 4-NO2FePc. The presence of the peripherally substituted phthalocyanine complexes is found to alter the pigmentation property of the selected fungus. Safranin-phthalocyanine double staining technique using 3-NO2CoPc, 3-NO2ZnPc, 4-NO2FePc and 2, 9, 16, 23-tetrahydroxy iron(III)chlorophthalocyanine [4-OHFePc] on the stem sections of Hemidesmus indicus R Br and Polygonum punctatum Buch-Hum have been studied.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88689228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DEVELOPMENT OF AN AGRO TECHNIQUE FOR LARGE-SCALE PRODUCTION OF GERANIUM’S PLANTLETS FOR CULTIVATION AND BRINJAL INTERCROPPING","authors":"S. K. Bose, R. Bansal, N. Sangwan","doi":"10.55218/jasr.202213905","DOIUrl":"https://doi.org/10.55218/jasr.202213905","url":null,"abstract":"Essential oil-bearing medicinal and aromatic plant Pelargonium graveolense is commonly known as rose-scented geranium because of its characteristic rose like smell. Its essential oil possesses medicinal properties such as insect repellent properties and also used in fragrance and food industry. Its demand is very high because of the above use in India and the worldwide market. This experiment is designed to develop an agro technique method for large scale production of geranium plantlets (cultivar CIM-Pawan) at field conditions using simple stem cutting method at North Indian field conditions in Uttar Pradesh, India. And also introduce a new method of intercropping cultivation of geranium in Brinjal (Solanum melongena) that is developed. This experiment was designed in such a manner to developed thousand plantlets from one year old a single mother plants. As we know near about 30,000 stem cuttings are required for planting an area of one hectare land. So focusing on large demands of plantlets developed an agro technique that is able to fulfil the requirements. The crops were raised using one month olds plantlets transplanting, viz. with intercropping in Brinjal. After harvesting oil was extracted by hydro-distillation using Clevenger apparatus and analyzed by gas chromatography (GC). The Citronellol/Geraniol ratio (C: G), quality determining factor was found to 1.23. The GC and GC-MS analysis results indicated that the essential oil components, quality and quantity were significant. The major constituents of the essential oil were Citronellol (29.81%), Geraniol (24.23%), Linalool (3.12%), Iso-menthone (4.09%), Citronellyl formate (7.51%), Geranyl formate (6.07%), and 10-epi-γ-eudesmol (2.70%).","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83584694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EVALUATION OF ANTI-INFLAMMATORY PROPERTIES OF ETHANOLIC LEAF, FLOWER AND SEED EXTRACTS OF LAGERSTROEMIA SPECIOSA (L.) PERS (LYTHRACEAE) AGAINST CARRAGEENAN-INDUCED ACUTE INFLAMMATION IN ALBINO RATS","authors":"S. Pavithran, P. Sujatha","doi":"10.55218/jasr.202213907","DOIUrl":"https://doi.org/10.55218/jasr.202213907","url":null,"abstract":"Lagerstroemia speciosa medicinal properties suggest that it may have anti-inflammatory effects on acute inflammation. The present study was performed to investigate the anti-inflammatory effect of L. speciosa ethanolic leaf, flower, and seed extract (LELE, LEFE, and LESE) on carrageenan-induced acute inflammation in rats. This plant is commonly called Pride of India refers to the various parts of this plant, including the leaves, flowers, and seeds, which are used as folk medicine. It has been demonstrated that the phytochemical and anti-inflammatory activities are effective in the treatment of inflammatory conditions in traditional medicine. The qualitative phytochemical investigation of L. speciosa leaf, flower, and seed revealed that it contained steroids, terpenoids, glycosides, polyphenolic compounds, amino acids, saponins, alkaloids, flavonoids, reducing sugars, tannins, and many other active metabolites. Studies have shown active antiinflammatory ingredients in L. speciosa ethanolic extracts of leaf (LELE), flower (LEFE), and seed (LESE). The ethanolic extracts of L. speciosa (LELE, LEFE and LESE) were investigated for anti-inflammatory activity in carrageenan-induced paw edema in albino rats and compared to control and standard drug, Diclofenac injection. The experimental plant extracts were given orally at a concentration of 250 and 500 mg/kg b.w. before carrageenan injection. In the paw edema evaluation, the paw volume was measured in the early (from 0 min-3 h) and late (4-6 h) phases of edema formation. In acute inflammation paw models, the ethanol extracts significantly reduced paw edema. The result obtained is indicative that the ethanolic extract of leaf and seed with high dose of 500 mg/kg b.w. produced 42% of inhibition and is low as compared to the standard drug. Low dose of ethanolic flower extract of L. speciosa inhibitory is equal to the low dose of seed extract; it is 1% lower than the standard and 2% lower than the control.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76083942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"GREEN SYNTHESIS AND CHARACTERIZATION OF ALCHEMILLA VULGARIS SILVER NANOPARTICLES","authors":"Shilpee Jain, A. Yadav, R. Gothalwal","doi":"10.55218/jasr.202213909","DOIUrl":"https://doi.org/10.55218/jasr.202213909","url":null,"abstract":"Among all the nanoparticles synthesized; silver nanoparticles have attained special place in the area of nano technology because of their antimicrobial, nontoxic, environmentally safe and biomedical applications. In general; their syntheses involves the use of hazardous chemicals or costly physical methods. However, the biological processes are making their ways in between and proving their advantages over them. The use of plants and their extracts is one of the most valuable methods which are gaining concerns due to their imperative biological benefits. Plants are not only beautiful but majestic because they are rich sources of various medicinally important substances. They explore the huge diversity which can be utilized towards rapid and single step protocol preparatory method for various nanoparticles keeping intact “the green principles” over the conventional ones and proving their dominance for medicinal importance. Here, in the presented work “one pot synthesis of silver nanoparticles” is described. Therefore; a simple, cost effective bio-reduction on the principle of “green synthesis” of silver nanoparticles using the Alchemilla vulgaris plant extract is reported. The beauty of the synthesis is: no involvement of any surfactant, catalyst or template. The aqueous silver ions are reduced to silver nanoparticles when exposed to plant extract. The bio-reduction and stabilization of so formed silver nanoparticles was monitored by UV-Vis spectrophotometry, FTIR spectroscopy, SEM, particle size and zeta potential.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"85 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79701270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Duraivathi, J. Jeya, J. Poongodi, H. J. Johnson
{"title":"GREEN SYNTHESIS OF CHROMIUM OXIDE NANOPARTICLES - STUDY OF ITS ANTIBACTERIAL, PHOTOCATALYTIC AND THERMODYNAMIC PROPERTIES","authors":"C. Duraivathi, J. Jeya, J. Poongodi, H. J. Johnson","doi":"10.55218/jasr.202213904","DOIUrl":"https://doi.org/10.55218/jasr.202213904","url":null,"abstract":"An endeavor has been made to report the herbal synthesis of chromium oxide (Cr2O3) nanoparticles using aqueous extract of nigella sativa seed extract as a capping agent and chromic sulphateas a precursor material. The structural, morphological and optical properties of the Cr2O3 nanoparticles were analyzed by X - ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM) and UV- Visible spectroscopy. The antibacterial efficacy of chromium oxide nanoparticles was tested against Staphylococcus aureus, Klebsiella pneumonia and Pseudomonas aeruginosa. The photocatalytic activity of biosynthesized Cr2O3 nanoparticles was evaluated by degrading methylene blue dye and Congo red dye under the irradiation of visible light. Apart from this, ultrasonic velocity, density and viscosity were measured for different concentrations of Cr2O3 nanofluid using ultrasonic techniques. Thermoacoustical such as adiabatic compressibility, free length, acoustic impedance, relaxation time and absorption coefficient values are computed from the measured data and the results are interpreted in terms of particle - fluid interactions.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86108959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A STUDY ON PREVALENCE OF PRE MENSTRUAL SYNDROME, ITS ASSOCIATION WITH DIETARY HABITS AND STRESS LEVELS AMONG ADOLOSCENT GIRLS STUDYING IN GIRLS COLLEGE OF HYDERABAD","authors":"Bashama Zehra, Mrs. Meena Patangay","doi":"10.55218/jasr.202213910","DOIUrl":"https://doi.org/10.55218/jasr.202213910","url":null,"abstract":"Pre-Menstrual Syndrome is a group of physical, psychological, and emotional symptoms that begins 7-14 days before menses and fade once menses begins. PMDD is a psychiatric diagnosis of PMS. The cause of PMS is unknown. Hence studies need to be conducted to know the various lifestyle and dietary habits that increases the risk of PMS. The aim was to study the dietary pattern of adolescent girls aged 17-19 years of Girls college of Hyderabad during the PMS period. The objectives were to study the prevalence, association between lifestyle habits, dietary pattern and stress with PMS in these adolescent girls. Adolescent girls of Girls College, answered a self- constructed, pre tested, standardized questionnaire for the prevalence study. Information on lifestyle and dietary habits, dietary preferences and symptoms observed in PMS period, and the observed stress level was collected. Chi – square test and non- parametric test was done to interpret the data. Among the 300 respondents, 19.3% had PMDD, 46.3% had moderate to severe PMS and 34.3% had mild/no PMS. There was an association between PMS and consuming high calorie foods, herbal teas during PMS period (p is less than 0.05) and also with stress (pis less than0.05) Reducing high calorie foods help to reduce PMS symptoms. Adequate sleep, less screen time and avoiding skipping of meals, consuming less fast food would reduce the prevalence. Having higher level of stress increases the risk of developing PMS or even PMDD.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73719223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. J. Priya, C. Duraivathi, J. Poongodi, K. Amudhavalli
{"title":"HERBAL SYNTHESIS OF IRON DOPED COBALT OXIDE NANOPARTICLE AND ITS APPLICATIONS","authors":"J. J. Priya, C. Duraivathi, J. Poongodi, K. Amudhavalli","doi":"10.55218/jasr.202213908","DOIUrl":"https://doi.org/10.55218/jasr.202213908","url":null,"abstract":"Iron doped cobalt oxide nanoparticles were prepared by using Eclipta alba leaves extract. The structural, optical and phase analysis of the synthesized nanoparticles are investigated by X-Ray Diffraction (XRD), Ultraviolet Visible Spectroscopy (UV), and Fourier Transform Infrared Spectroscopy (FTIR) respectively. Scanning Electron microscope (SEM), Energy Dispersive X-Ray Spectroscopy (EDX) and Dynamic Light Scattering (DLS) are used to study the surface morphological, elemental analysis and the hydrodynamic size of the prepared nanoparticles. Methylene Blue (MB) and Congo Red (CR) dye degradation efficacy of the iron doped cobalt oxide nanoparticles are examined using UV. Antibacterial activity for three different bacteria was done using disc diffusion method. Capacitative property of FeCo2O4 was proved by Cyclic Voltammetry (CV) analysis. Thermodynamic properties of the herbal synthesized particle were investigated using Ultrasonic technique using propylene glycol as a base fluid.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77619452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charu Jaiswal, Medha Chakraborty, Kushal Kant Pant, Vikas Chandra, D. Porte
{"title":"NANOPARTICLE AIDED TUMOR TARGETING AND CANCER DETECTION","authors":"Charu Jaiswal, Medha Chakraborty, Kushal Kant Pant, Vikas Chandra, D. Porte","doi":"10.55218/jasr.202213901","DOIUrl":"https://doi.org/10.55218/jasr.202213901","url":null,"abstract":"Cancer refers to a collective group of diseases involving abnormal, uncontrolled cell proliferation with the potential to spread to the other tissues from the location of origin. Various modes of treatments such as radiotherapy, chemotherapy, surgical methods, etc. are commonly available. However, these approaches are not very cost-effective and are accompanied by side effects. An emerging approach of targeted drug delivery or smart drug delivery with the assistance of nanoparticles (NPs) and also in combination with immunological therapies has proven to show great potential in cancer treatment with an additional advantage of having the least side effects. Stimulus-sensitive smart nanomaterials have been designed to specifically target the cancer cells, causing no damage to the healthy cells. This is attained using Poly (lactic-co-glycolic acid) (PLGA), PEGylated NPs, αvβ3-integrin-specific lipid NPs, NP-based radiosensitizers (NBRs), and NP drones. Moreover, not only the specific targeting but the advances allow the detection of these drug-loaded NPs with the help of plasmonic Biosensor and fluorescence nanoprobes that emits fluorescence as it comes in contact with the target. This article describes the application of NPs in targeting the tumor cells as well as the recent researches going on to facilitate easier & cheaper modes of treatment using nanotechnology.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81077038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SYNTHESIS AND SPECTROSCOPIC STUDIES ON OXOVANADIUM COMPLEX WITH LIGANDS HAVING N, N-DONOR SITES","authors":"Y. Singh, R. Jha","doi":"10.55218/jasr.202213805","DOIUrl":"https://doi.org/10.55218/jasr.202213805","url":null,"abstract":"The present investigation is concerned with a method by the reaction of vanadylsulphate with nitrogen containing ligands N, N donor sites like dicyandiamide, methyldicyandiamide and phenyldicyandiamide in methanol and refluxed. The tentative structure of these complexes has been proposed on the basis of elemental analysis, magnetic moment and spectral (IR, EPR) data. The IR and EPR spectra of all the complexes were recorded at room temperature and at liquid nitrogen temperature. The room temperature EPR spectrum shows anisotropy because the band is observed separately.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79793491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ANTIMICROBIAL ACTIVITY OF SOLVENT EXTRACTS OF POLYGONATUM CIRRHIFOLIUM (MAHAMEDHA) AND HABENERIA INTERMEDIA (RIDDHI)","authors":"Reetu Sharma, Ranjit Singh","doi":"10.55218/jasr.202213806","DOIUrl":"https://doi.org/10.55218/jasr.202213806","url":null,"abstract":"Antimicrobial drugs have caused a dramatic change not only of the treatment of infectious diseases but of the mankind as a whole. Antimicrobial chemotherapy made remarkable advances, However, in reality emerging and re-emerging infectious diseases have left us facing a counter charge from infections. Infections with drug resistant organisms remain pertinent problem in clinical practice that is difficult to solv. (In the present study, the antimicrobial activity of the polar (methanolic) plant extracts viz. Polygonatum cirrhifolium (Mahamedha) and Habeneria intermedia (Riddhi) were determined at 200μg/ml. The results showed significant antimicrobial activity against the pathogens studied viz. Staphylococcus epidermidis, Aspergillus niger and Candida albicans. The potent antimicrobial extracts were having MIC values in the range of 150-200 μg/ml.","PeriodicalId":14906,"journal":{"name":"Journal of Advanced Scientific Research","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81617877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}