Jornal de pediatria最新文献_第4页

Erratum to: “Cross-cultural adaptation, validity, and reliability of the Child and Adolescent Behavior Inventory (CABI) for use in Brazil” (Jornal de Pediatria 99 (2023) 413–422) 勘误："在巴西使用的儿童和青少年行为量表（CABI）的跨文化适应性、有效性和可靠性》（Jornal de Pediatria 99 (2023) 413-422）的勘误。

IF 2.8 4区医学

Jornal de pediatria Pub Date : 2024-06-26 DOI: 10.1016/j.jped.2024.06.001

引用次数: 0

Instrumental swallowing studies for the prevention of pulmonary morbidity in children and the importance of multi-disciplinary teams 预防儿童肺部疾病的工具性吞咽研究和多学科团队的重要性。

IF 2.8 4区医学

Jornal de pediatria Pub Date : 2024-05-29 DOI: 10.1016/j.jped.2024.05.002

引用次数: 0

Risk of autism spectrum disorder in children with infantile epileptic spasms syndrome: a retrospective study in a single center in Brazil 婴幼儿癫痫痉挛综合征患儿患自闭症谱系障碍的风险：巴西一家中心的回顾性研究。

IF 2.8 4区医学

Jornal de pediatria Pub Date : 2024-05-29 DOI: 10.1016/j.jped.2024.04.006

{"title":"Risk of autism spectrum disorder in children with infantile epileptic spasms syndrome: a retrospective study in a single center in Brazil","authors":"","doi":"10.1016/j.jped.2024.04.006","DOIUrl":"10.1016/j.jped.2024.04.006","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to investigate the prevalence of autism spectrum disorder and its possible correlations with clinical characteristics in patients with infantile epileptic spasms syndrome in a single center in Brazil.</p></div><div><h3>Methods</h3><p>This retrospective cross-sectional study examined 53 children with the diagnosis of infantile epileptic spasms syndrome prior to an autism spectrum disorder assessment. Participants were divided into two groups based on the presence or absence of autism spectrum disorder. Available variables (sex, medications, median age at onset of infantile epileptic spasms syndrome, and presence of comorbidities) were compared using Mann–Whitney U or chi-square tests.</p></div><div><h3>Results</h3><p>Among the included patients, 12 (23 %) were diagnosed with autism spectrum disorder, corresponding to a relative risk of 0.29 (95 % confidence interval 0.174–0.492). The age at the first seizure ranged from 3 to 15 months, with a mean of 6.65 months. This age significantly differed between participants with autism spectrum disorder (10.58 months) and those without (5.43 months), <em>p</em><0.001.</p></div><div><h3>Conclusion</h3><p>Children with infantile epileptic spasms syndrome have a higher risk of being diagnosed with autism spectrum disorder. Later age of onset and period of spasm occurrence might be predisposing risk factors.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755724000688/pdfft?md5=e9958f9112a525471d638ccaa644e577&pid=1-s2.0-S0021755724000688-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141186009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patients with genital ambiguity referred without a sex definition: the relationship between clinical picture and defined sex of rearing. 未确定性别而转诊的生殖器模糊患者：临床表现与确定的抚养性别之间的关系。

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-05-29 DOI: 10.1016/j.jped.2024.05.001

Henrique C Santos, Beatriz A Barros, Mayra S El-Beck, Marcio L Miranda, Mara S Guaragna, Helena Fabbri-Scallet, Taís N Mazzola, Tarsis P Vieira, Maricilda P Mello, Antonia P Marques-de-Faria, Andrea T Maciel-Guerra, Gil Guerra-Junior

{"title":"Patients with genital ambiguity referred without a sex definition: the relationship between clinical picture and defined sex of rearing.","authors":"Henrique C Santos, Beatriz A Barros, Mayra S El-Beck, Marcio L Miranda, Mara S Guaragna, Helena Fabbri-Scallet, Taís N Mazzola, Tarsis P Vieira, Maricilda P Mello, Antonia P Marques-de-Faria, Andrea T Maciel-Guerra, Gil Guerra-Junior","doi":"10.1016/j.jped.2024.05.001","DOIUrl":"10.1016/j.jped.2024.05.001","url":null,"abstract":"<p><strong>Objective: </strong>It was to verify the association between the definition of sex of rearing and, clinical and cytogenetic features among patients with genital ambiguity referred without a sex assignment.</p><p><strong>Methods: </strong>The sample consisted of 133 patients with genital ambiguity seen at a single reference service. These patients did not have a defined social sex at the first consultation and their etiological diagnosis was obtained during follow-up.</p><p><strong>Results: </strong>A total of 133 cases were included, 74 of which were reared as males and 59 as females. No correlation was found between the year of birth and the year of the first consultation with the definition of sex of rearing. However, the definition of sex of rearing was associated with age at the first consultation, severity of genital ambiguity, presence of palpable gonad(s), presence of uterus on ultrasound, karyotype, and diagnosis. Palpable gonad(s), more virilized genitalia, absence of a uterus on ultrasound, 46, XY karyotype, or a karyotype with sex chromosome abnormalities emerged as strong predictors for defining male sex. All 77 (58 %) patients over 18 years old had a gender identity in accordance with the sex of rearing; though 9 of 77 (12 %) had homo or bisexual orientation, especially girls with Congenital Adrenal Hyperplasia.</p><p><strong>Conclusions: </strong>Clinical and cytogenetic data were strongly associated with the definition of the sex of rearing of children with genital ambiguity referred to a DSD center without sex assignment. Management in a specialized center allows the establishment of a gender identity in accordance with the sex of rearing.</p>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141186006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The trajectory of head circumference and neurodevelopment in very preterm newborns during the first two years of life: a cohort study 早产儿头围和神经发育的轨迹：一项队列研究。

IF 2.8 4区医学

Jornal de pediatria Pub Date : 2024-05-25 DOI: 10.1016/j.jped.2024.04.005

{"title":"The trajectory of head circumference and neurodevelopment in very preterm newborns during the first two years of life: a cohort study","authors":"","doi":"10.1016/j.jped.2024.04.005","DOIUrl":"10.1016/j.jped.2024.04.005","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the growth trajectory of head circumference and neurodevelopment, and to correlate head circumference with cognitive, language, and motor outcomes during the first two years.</p></div><div><h3>Method</h3><p>Prospective cohort study in a tertiary hospital including 95 newborns under 32 weeks or 1500 g. Neonates who developed major neonatal morbidities were excluded. The head circumference was measured at birth, at discharge, and at term-equivalent age, 1, 3, 5, 12, 18, and 24 months of corrected age, and the Bayley Scales (Bayley-III) were applied at 12, 18 and 24 months of corrected age to assess cognitive, language and, motor domains. Scores below 85 were classified as mild/moderate deficits and scores below 70 as severe deficits. The association between head circumference Z score and Bayley scores was assessed using Pearson's correlation. The study considered a significance level of 0.05.</p></div><div><h3>Results</h3><p>There was a decrease of -0.18 in the head circumference Z score between birth and discharge and the catch-up occurred between discharge and 1 month (an increase of 0.81 in the Z score). There was a positive correlation between head circumference and Bayley scores at 18 months. There was also a positive correlation between head circumference at discharge and at 5 months with the three domains of the Bayley.</p></div><div><h3>Conclusion</h3><p>Serial measurements of head circumference provide knowledge of the trajectory of growth, with early catch-up between discharge and 1 month, as well as its association with neurodevelopment. Head circumference is therefore a valuable clinical marker for neurodevelopment, especially in very preterm newborns.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755724000676/pdfft?md5=21d54f3cb6f420f0cd34e4e9de714205&pid=1-s2.0-S0021755724000676-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141161119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inflammatory markers in prepubertal children and their associations with abdominal fat 青春期前儿童的炎症指标及其与腹部脂肪的关系。

IF 2.8 4区医学

Jornal de pediatria Pub Date : 2024-05-08 DOI: 10.1016/j.jped.2024.03.015

{"title":"Inflammatory markers in prepubertal children and their associations with abdominal fat","authors":"","doi":"10.1016/j.jped.2024.03.015","DOIUrl":"10.1016/j.jped.2024.03.015","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the association between inflammatory markers and abdominal fat assessed by ultrasound in prepubertal children with and without excess weight.</p></div><div><h3>Methods</h3><p>A cross-sectional study involving 241 prepubertal children, 156 with obesity, 37 with overweight, and 48 with normal weight, aged five to ten years, who were followed at a research unit on Childhood Obesity from a teaching hospital belonging to a public health system. The concentration of interleukin-6, tumor necrosis factor-α and C-reactive protein were assessed and regression analyses, considering outcome variables such as abdominal wall and intra-abdominal fat thickness measured by ultrasound, were performed.</p></div><div><h3>Results</h3><p>The findings highlighted an association between abdominal fat and inflammatory markers, even in children at this young age group. Subcutaneous fat showed a stronger association with inflammatory biomarkers compared to intra-abdominal fat when performing logistic regression, with a positive association between tumor necrosis factor-α and abdominal wall thickness equal to or greater than the 75th percentile in adjusted logistic regression (OR: 18.12; CI 95 %: 1.57: 209.55).</p></div><div><h3>Conclusions</h3><p>Abdominal wall fat, in contrast to what is often observed in adults, appears to have a greater impact on chronic inflammation related to excessive weight in very young children.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755724000652/pdfft?md5=1e16896177e4f238a539ac66b395247b&pid=1-s2.0-S0021755724000652-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140908620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sexual violence against children and adolescents in Paraná State: geospatial analysis and main socioeconomic indicators 巴拉那州针对儿童和青少年的性暴力：地理空间分析和主要社会经济指标。

IF 2.8 4区医学

Jornal de pediatria Pub Date : 2024-05-01 DOI: 10.1016/j.jped.2024.03.014

{"title":"Sexual violence against children and adolescents in Paraná State: geospatial analysis and main socioeconomic indicators","authors":"","doi":"10.1016/j.jped.2024.03.014","DOIUrl":"10.1016/j.jped.2024.03.014","url":null,"abstract":"<div><h3>Objective</h3><p>Child sexual violence is a multidimensional problem of many contemporary societies, affecting people of all sexes, social stratum and age groups. Offenses involving children and adolescents are more serious, given their total or partial dependence on parents and caregivers. Information on child sexual violence in Brazil is found in raw form and without detail. The objective was to compare the information with social and economic data in the state of Paraná.</p></div><div><h3>Methods</h3><p>The authors conducted a retrospective study of secondary data from the Notifiable Diseases Information System (SINAN) on cases of sexual violence involving victims aged 0 to 19 years. Results are presented according to notification characteristics. The authors applied exploratory spatial data analysis to assess spatial autocorrelations and investigated relationships by the ordinary least squares regression model.</p></div><div><h3>Results</h3><p>Between 2017 and 2021, there were 13,403 reports of child sexual violence in Paraná State, Brazil. Most victims (82.8%) were female and aged between 10 and 14 years. The majority of sexual violence cases (67.8%) occurred in the home environment. The highest rates on a population basis were observed in the North Central and Greater Curitiba regions, mainly in cities with higher population density and with higher rates of other types of violence.</p></div><div><h3>Conclusion</h3><p>The results provide data that can promote a broader understanding of the distribution of sexual violence and the state and associated variations. It is expected to improve the provision of care for victims of child sexual violence and assist in strategic planning to prevent future offenses.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755724000561/pdfft?md5=1bc2296d97defa57803441efafa1f7aa&pid=1-s2.0-S0021755724000561-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140848689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The death risk of pediatric patients with cancer-related sepsis requiring continuous renal replacement therapy: a retrospective cohort study 需要持续肾脏替代治疗的癌症相关败血症儿科患者的死亡风险：一项回顾性队列研究

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-05-01 DOI: 10.1016/j.jped.2024.04.004

Xiaoxuan Ma, J. Dou, Chunxia Wang, H. Miao, Jingyi Shi, Yun Cui, Yiping Zhou, Yucai Zhang

引用次数: 0

Acupuncture for pediatric chronic pain: A systematic review. 针灸治疗小儿慢性疼痛：系统综述。

IF 3.3 4区医学

Jornal de pediatria Pub Date : 2024-04-30 DOI: 10.1016/j.jped.2024.03.013

João Roberto Bissoto, José Udevanier Rebouças da Silva Júnior, Gabrielle Pignoli Alvares, Flávia H Santos, Claudio Arnaldo Len

{"title":"Acupuncture for pediatric chronic pain: A systematic review.","authors":"João Roberto Bissoto, José Udevanier Rebouças da Silva Júnior, Gabrielle Pignoli Alvares, Flávia H Santos, Claudio Arnaldo Len","doi":"10.1016/j.jped.2024.03.013","DOIUrl":"10.1016/j.jped.2024.03.013","url":null,"abstract":"<p><strong>Objectives: </strong>To survey, analyze and discuss the scientific evidence supporting the use of acupuncture and related techniques in the management of chronic pain in the pediatric population.</p><p><strong>Sources: </strong>A survey of databases (MEDLINE, Scopus and Scielo) was carried out with search strategies, following the PRISMA statement, without limits on publication dates and languages. Clinical studies (clinical trials, single-arm, and case series) were accepted for review if they included participants aged up to 22 years. Study quality was assessed by MMAT, and the randomized clinical trial was analyzed under the STRICTA criteria.</p><p><strong>Summary of the findings: </strong>2369 articles were retrieved. After excluding repetitions, 1335 underwent the initial selection. Only 16 articles were selected for full reading, of which 5 were included in the review, being two case series, two single-arm studies, and one randomized clinical trial. The articles were considered of good quality by the adopted criteria.</p><p><strong>Conclusion: </strong>The analyzed studies showed important clinical results such as the reduction of pain intensity, and improvement in school attendance and social life. However, there are many limitations in study design and sample size. Therefore, there is weak evidence to support the use of acupuncture in the context of pediatric chronic pain, but the positive results reinforce the need for further investigation of the topic with the conduct of larger and well-designed studies, to obtain more data and greater scientific conviction of the findings.</p>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140856322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inhaled magnesium versus inhaled salbutamol in rescue treatment for moderate and severe asthma exacerbations in pediatric patients 吸入镁与吸入沙丁胺醇在儿童患者中度和重度哮喘加重的抢救治疗中的比较

IF 2.8 4区医学

Jornal de pediatria Pub Date : 2024-04-30 DOI: 10.1016/j.jped.2024.03.012

{"title":"Inhaled magnesium versus inhaled salbutamol in rescue treatment for moderate and severe asthma exacerbations in pediatric patients","authors":"","doi":"10.1016/j.jped.2024.03.012","DOIUrl":"10.1016/j.jped.2024.03.012","url":null,"abstract":"<div><h3>Objective</h3><p>To compare the effectiveness of inhaled Magnesium Sulfate associated with Salbutamol versus Inhaled Salbutamol alone in patients with moderate and severe asthma exacerbations.</p></div><div><h3>Method</h3><p>Clinical, prospective and randomized study with patients between 3 and 14 years of age divided into two groups: one to receive inhaled salbutamol associated with magnesium sulfate (GSM), the other to receive inhaled salbutamol alone (GS). The sample consisted of 40 patients, 20 patients in each group. Severity was classified using the modified Wood-Downes score, with values between 4 and 7 classified as moderate and 8 or more classified as severe.</p></div><div><h3>Results</h3><p>Post-inhalation scores decreased both in patients who received salbutamol and magnesium and in those who received salbutamol alone, with no statistically significant difference between the groups.</p></div><div><h3>Conclusions</h3><p>Despite the benefits when administered intravenously, inhalation of the drug alone or in combination did not reduce the severity of the exacerbation.</p></div>","PeriodicalId":14867,"journal":{"name":"Jornal de pediatria","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0021755724000548/pdfft?md5=66606e1068e177d40cc480ccfa8fc612&pid=1-s2.0-S0021755724000548-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140836905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0