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The Enigmata of Cardioprotection With SGLT2 Inhibition 抑制SGLT2的心脏保护之谜
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/j.jacbts.2024.08.010
Gerd Heusch MD, Petra Kleinbongard PhD
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引用次数: 0
The Lung and Winding Road 蜿蜒曲折的道路
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/j.jacbts.2024.11.013
Harvey G. Roweth PhD
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引用次数: 0
Recognizing Early Career Translational Investigators 认识早期职业翻译研究者
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/j.jacbts.2024.12.002
Douglas L. Mann MD (Editor-in-Chief: JACC: Basic to Translational Science)
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引用次数: 0
JACC: Basic to Translational Science 从基础到转化科学
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/j.jacbts.2024.12.001
Brian H. Annex MD, Michael R. Bristow MD, PhD, Nikolaus G. Frangogiannis MD, Daniel P. Kelly MD, Maria Kontaridis PhD, Peter Libby MD, William Robb MacLellan MD, Coleen A. McNamara MD, Douglas L. Mann MD, Geoffrey S. Pitt MD, PhD, Karin R. Sipido MD, PhD
{"title":"JACC: Basic to Translational Science","authors":"Brian H. Annex MD, Michael R. Bristow MD, PhD, Nikolaus G. Frangogiannis MD, Daniel P. Kelly MD, Maria Kontaridis PhD, Peter Libby MD, William Robb MacLellan MD, Coleen A. McNamara MD, Douglas L. Mann MD, Geoffrey S. Pitt MD, PhD, Karin R. Sipido MD, PhD","doi":"10.1016/j.jacbts.2024.12.001","DOIUrl":"10.1016/j.jacbts.2024.12.001","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"10 1","pages":"Page 129"},"PeriodicalIF":8.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Empagliflozin in Acute Myocardial Infarction Reduces No-Reflow and Preserves Cardiac Function by Preventing Endothelial Damage 恩格列净治疗急性心肌梗死可通过预防内皮损伤减少无回流并保护心功能
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/j.jacbts.2024.08.003
Panagiota Efstathia Nikolaou PhD , Lara S.F. Konijnenberg MD, PhD , Ioannis V. Kostopoulos PhD , Marios Miliotis PhD , Nikolaos Mylonas MSc , Anastasios Georgoulis PhD , George Pavlidis MD, PhD , Carolien T.A. Kuster Msc , Vince P.A. van Reijmersdal Msc , Tom T.J. Luiken Msc , Anna Agapaki PhD , Rona Roverts PhD , Nikolaos Orologas PhD , Dimitris Grigoriadis PhD , Gaëtan Pallot PhD , Pierre Boucher MSc , Nikolaos Kostomitsopoulos PhD , Michael Paul Pieper PhD , Stéphane Germain PhD , Yannis Loukas PhD , Ioanna Andreadou PhD
{"title":"Empagliflozin in Acute Myocardial Infarction Reduces No-Reflow and Preserves Cardiac Function by Preventing Endothelial Damage","authors":"Panagiota Efstathia Nikolaou PhD ,&nbsp;Lara S.F. Konijnenberg MD, PhD ,&nbsp;Ioannis V. Kostopoulos PhD ,&nbsp;Marios Miliotis PhD ,&nbsp;Nikolaos Mylonas MSc ,&nbsp;Anastasios Georgoulis PhD ,&nbsp;George Pavlidis MD, PhD ,&nbsp;Carolien T.A. Kuster Msc ,&nbsp;Vince P.A. van Reijmersdal Msc ,&nbsp;Tom T.J. Luiken Msc ,&nbsp;Anna Agapaki PhD ,&nbsp;Rona Roverts PhD ,&nbsp;Nikolaos Orologas PhD ,&nbsp;Dimitris Grigoriadis PhD ,&nbsp;Gaëtan Pallot PhD ,&nbsp;Pierre Boucher MSc ,&nbsp;Nikolaos Kostomitsopoulos PhD ,&nbsp;Michael Paul Pieper PhD ,&nbsp;Stéphane Germain PhD ,&nbsp;Yannis Loukas PhD ,&nbsp;Ioanna Andreadou PhD","doi":"10.1016/j.jacbts.2024.08.003","DOIUrl":"10.1016/j.jacbts.2024.08.003","url":null,"abstract":"<div><div>Empagliflozin treatment before acute myocardial infarction mainly targets the endothelial cell transcriptome. Empagliflozin treatment before and after myocardial infarction decreased no reflow and microvascular injury, leading to reduced infiltration of inflammatory cells, reduced infarct size, and improved cardiac function in mice. In diabetic patients receiving empagliflozin after myocardial infarction, perfused boundary region, flow-mediated dilation, and global longitudinal strain were improved.</div></div>","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"10 1","pages":"Pages 43-61"},"PeriodicalIF":8.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142207141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Full Issue PDF 完整版PDF
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/S2452-302X(24)00480-7
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引用次数: 0
Targeting IL-33/ST2 Signaling Alters Cardiac Structure and Function in Hypertensive Heart Disease 靶向IL-33/ST2信号改变高血压心脏病的心脏结构和功能
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2025-01-01 DOI: 10.1016/j.jacbts.2024.09.006
Jean W. Wassenaar MD PhD , C. Duncan Smart MD PhD , Daniel J. Fehrenbach PhD , Vineet Agrawal MD PhD , Matthew M. Dungan BS , Niki L. Fortune , Lin Zhong MD PhD , Anna R. Hemnes MD , R. Stokes Peebles Jr. MD , Francis J. Miller Jr. MD , Amanda C. Doran MD PhD , Meena S. Madhur MD PhD
{"title":"Targeting IL-33/ST2 Signaling Alters Cardiac Structure and Function in Hypertensive Heart Disease","authors":"Jean W. Wassenaar MD PhD ,&nbsp;C. Duncan Smart MD PhD ,&nbsp;Daniel J. Fehrenbach PhD ,&nbsp;Vineet Agrawal MD PhD ,&nbsp;Matthew M. Dungan BS ,&nbsp;Niki L. Fortune ,&nbsp;Lin Zhong MD PhD ,&nbsp;Anna R. Hemnes MD ,&nbsp;R. Stokes Peebles Jr. MD ,&nbsp;Francis J. Miller Jr. MD ,&nbsp;Amanda C. Doran MD PhD ,&nbsp;Meena S. Madhur MD PhD","doi":"10.1016/j.jacbts.2024.09.006","DOIUrl":"10.1016/j.jacbts.2024.09.006","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"10 1","pages":"Pages 107-109"},"PeriodicalIF":8.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143165280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Miniature Implantable Left Atrial/Ventricular Pump to Treat Symptoms of Heart Failure With Preserved Ejection Fraction 微型植入左心房/心室泵治疗保留射血分数的心力衰竭症状：一种新型装置治疗方法
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/j.jacbts.2024.10.004
Andrew J. Malone PhD, MSc , Kurdo Araz MSc, BMSc , Jemil Saidi MSc, BSc , Donald Hickey MDes , Darragh Colgan PhD, MBA, BEng , Aamir Hameed MBBS, MD
{"title":"Miniature Implantable Left Atrial/Ventricular Pump to Treat Symptoms of Heart Failure With Preserved Ejection Fraction","authors":"Andrew J. Malone PhD, MSc ,&nbsp;Kurdo Araz MSc, BMSc ,&nbsp;Jemil Saidi MSc, BSc ,&nbsp;Donald Hickey MDes ,&nbsp;Darragh Colgan PhD, MBA, BEng ,&nbsp;Aamir Hameed MBBS, MD","doi":"10.1016/j.jacbts.2024.10.004","DOIUrl":"10.1016/j.jacbts.2024.10.004","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"9 12","pages":"Pages 1385-1387"},"PeriodicalIF":8.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Semaglutide Reduces Cardiomyocyte Size and Cardiac Mass in Lean and Obese Mice 西马鲁肽减少瘦和肥胖小鼠心肌细胞大小和心脏质量。
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/j.jacbts.2024.07.006
Matthew D. Martens PhD , Yasser Abuetabh PhD , Mya A. Schmidt BSc , Matthieu C.P. Zolondek BSc , Heidi L. Silver , Jody L. Levasseur , Mourad Ferdaoussi PhD , Jason R.B. Dyck PhD
{"title":"Semaglutide Reduces Cardiomyocyte Size and Cardiac Mass in Lean and Obese Mice","authors":"Matthew D. Martens PhD ,&nbsp;Yasser Abuetabh PhD ,&nbsp;Mya A. Schmidt BSc ,&nbsp;Matthieu C.P. Zolondek BSc ,&nbsp;Heidi L. Silver ,&nbsp;Jody L. Levasseur ,&nbsp;Mourad Ferdaoussi PhD ,&nbsp;Jason R.B. Dyck PhD","doi":"10.1016/j.jacbts.2024.07.006","DOIUrl":"10.1016/j.jacbts.2024.07.006","url":null,"abstract":"","PeriodicalId":14831,"journal":{"name":"JACC: Basic to Translational Science","volume":"9 12","pages":"Pages 1429-1431"},"PeriodicalIF":8.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Where Comity in Science Goes to Die 科学中的团结走向消亡。
IF 8.4 1区 医学
JACC: Basic to Translational Science Pub Date : 2024-12-01 DOI: 10.1016/j.jacbts.2024.11.003
Douglas L. Mann MD (Editor-in-Chief, JACC: Basic to Translational Science)
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引用次数: 0
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