JDR Clinical & Translational Research最新文献

{"title":"Randomized Trial to Test a Chemo-Mechanical Antiplaque Regimen as Adjunct to Periodontal Therapy.","authors":"L Li, Y Hayashi-Okada, K L Falkner, S Cervi, S Andrusz, Y Shimizu, J J Zambon, K L Kirkwood, R E Schifferle, P I Diaz","doi":"10.1177/23800844231167065","DOIUrl":"10.1177/23800844231167065","url":null,"abstract":"<p><strong>Background: </strong>The control of dental biofilm regrowth after nonsurgical periodontal therapy is associated with better clinical outcomes. However, many patients have difficulty achieving optimal plaque control. Subjects with diabetes, in which immune and wound-healing responses are typically impaired, may benefit from intensive antiplaque control regimens after scaling and root planing (SRP).</p><p><strong>Objectives: </strong>This study aimed to evaluate the effects of an intensive, at-home, chemical, and mechanical antiplaque regimen as an adjunct to SRP for the treatment of moderate to severe periodontitis. A secondary objective was to compare responses in subjects with type 2 diabetes and nondiabetics.</p><p><strong>Methods: </strong>This was a 6-mo, single-center, parallel-group, randomized trial. The test group received SRP and oral hygiene instructions, and subjects were instructed to use a 0.12% chlorhexidine gluconate mouthrinse twice a day for 3 mo and utilize rubber interproximal bristle cleaners twice a day for 6 mo. The control group received SRP and oral hygiene instructions. The main outcome was change in mean probing depth (PD) from baseline to 6 mo. Secondary outcomes included change in sites with deep PDs, mean clinical attachment level, bleeding on probing, plaque index, hemoglobin A1C, fasting blood glucose, C-reactive protein, and taste assessment. This study was registered at ClinicalTrials.gov as NCT04830969.</p><p><strong>Results: </strong>In total, 114 subjects were randomized to either treatment. Eighty-six subjects completed the trial with no missing visits. Neither an intention-to-treat nor a per-protocol analysis showed statistically significant differences between treatment groups in mean PD at 6 mo. In a subgroup analysis, subjects with diabetes in the test group showed a statistically significant greater reduction in mean PD at 6 mo when compared to subjects with diabetes receiving the control treatment (Δ = 0.15, <i>P</i> = 0.04), while there were no differences within nondiabetics (Δ = 0.02, <i>P</i> = 0.75).</p><p><strong>Conclusion: </strong>Outcomes in subjects with diabetes may be improved by chemo-mechanical antiplaque measures after nonsurgical periodontal therapy.</p><p><strong>Knowledge transfer statement: </strong>\u0000 <i>This study suggests diabetic subjects may benefit from an intensive, at-home, chemical, and mechanical antiplaque regimen to improve nonsurgical periodontal therapy outcomes.</i>\u0000 </p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9416924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Policy Briefs to Communicate Dental Research Findings to Policymakers.","authors":"J N Lee, C M Hill, D L Chi","doi":"10.1177/23800844231171831","DOIUrl":"10.1177/23800844231171831","url":null,"abstract":"<p><strong>Objectives: </strong>New scientific knowledge is not always available to decision makers. Policy briefs are a way that dental researchers can communicate research findings to policymakers. This study compares usefulness of 2 types of policy briefs about sugar-sweetened beverage (SSB) intake and tooth decay.</p><p><strong>Methods: </strong>We developed 2 policy brief types (data focused and narrative focused) and emailed a randomly assigned policy brief to 825 policymakers and staff from 3 levels of government (city, county, and state) in Washington State. Participants completed a 22-item online questionnaire. There were 4 study outcomes: whether the brief was understandable, whether the brief was credible, likelihood of use, and likelihood to be shared (each measured on a 5-point Likert-like scale). The <i>t</i> test was used to evaluate whether outcomes differed by policy brief type and government level (α = 0.05).</p><p><strong>Results: </strong>There were 108 respondents (adjusted response rate 14.6%). About 41.6% of participants were in city government, 26.9% were in county government, and 29.6% were in state government. Participants reported that both data- and narrative-focused briefs were understandable (mean rating [MR] and standard deviation [SD]: 4.15 ± 0.68 and 4.09 ± 0.81, respectively; <i>P</i> = 0.65) and credible (MR and SD: 4.13 ± 0.70 and 4.09 ± 0.70, respectively; <i>P</i> = 0.74), but they were not likely to use (MR and SD: 2.71 ± 1.15 and 2.55 ± 1.28, respectively; <i>P</i> = 0.51) or share it (MR and SD: 2.62 ± 1.04 and 2.66 ± 1.30, respectively; <i>P</i> = 0.87). The likelihood of sharing briefs differed significantly by level of government (<i>P</i> = 0.017). Participants at the state level were more likely to share information from the briefs (mean rating and SD: 3.10 ± 0.80) than city- and county-level participants (MR and SD: 2.62 ± 1.27, and 2.24 ± 1.21, respectively).</p><p><strong>Conclusion: </strong>Both data- and narrative-focused policy briefs may be a useful way to communicate dental research findings to policymakers, but additional steps are needed to ensure that briefs are used and shared.</p><p><strong>Knowledge transfer statement: </strong>Researchers should disseminate their research findings to maximize scientific impact. Our study findings indicate that policy briefs may be a useful way to communicate dental research findings to policymakers, but additional research is needed on the best ways to disseminate findings.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9686810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deliberative Improvement of Oral Care Quality: The Horizon Europe DELIVER Project.","authors":"S Listl, N Bostanci, M Byrne, J Eigendorf, G van der Heijden, M Lorenz, P Melo, K Rosing, P Vassallo, E B van Veen","doi":"10.1177/23800844231189484","DOIUrl":"10.1177/23800844231189484","url":null,"abstract":"<p><strong>Knowledge transfer statement: </strong>The EU DELIVER project aims to enhance the quality of oral health care through codevelopment and coproduction of solutions together with citizens/patients, providers, and policymakers. The unique multicountry nature of the project will facilitate fast-track prototype development and testing of innovative QI approaches in select countries. Reflective learning regarding the transferability of findings between different countries and settings offers unique opportunities to drive progress toward context-specific implementation of innovative oral health care QI approaches. The collective knowledge gained from the 7 European countries involved in DELIVER can also generate knowhow for improving the quality of oral health care in other countries around the globe.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10943595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9965249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Patient-Centered Dental Home: A Framework for Quality Measurement, Improvement, and Integration.","authors":"J B Herndon, J C Reynolds, P C Damiano","doi":"10.1177/23800844231190640","DOIUrl":"10.1177/23800844231190640","url":null,"abstract":"<p><strong>Objective: </strong>This study completed the development of a standardized patient-centered dental home (PCDH) framework to align and integrate with the patient-centered medical home. This study identified measure concepts and specific measures and standards to complete the 4-level measurement framework to implement and evaluate a PCDH. This study built on prior model development, which identified the PCDH definition and characteristics and the components nested within those characteristics.</p><p><strong>Methods: </strong>An environmental scan identified existing oral health care quality measure concepts, measures, and standards for rating by the project's National Advisory Committee (NAC). A modified Delphi process, adapted from the RAND appropriateness method, was used to obtain structured feedback from the NAC. NAC members rated measure concepts on importance and, subsequently, specific measures and standards on feasibility, validity, and actionability using a 1 to 9 rating scale. Criteria for model inclusion were based on median ratings and rating dispersion. Open-ended comments were elicited to inform model inclusion as well as identify additional concepts.</p><p><strong>Results: </strong>We identified more than 500 existing oral health care measures and standards. A structured process was used to identify a subset that best aligned with a PCDH for rating by the NAC. Four Delphi rounds were completed, with 2 rounds to rate measure concepts and 2 rounds to rate measures and standards. NAC quantitative ratings and qualitative comments resulted in a total of 61 measure concepts and 47 measures and standards retained for inclusion in the framework.</p><p><strong>Conclusions: </strong>The NAC ratings of measure concepts, and specific measures and standards nested within those concepts, completed the 4-level PCDH measurement framework. The resulting framework allows for the development and implementation of core measure sets to identify and evaluate a PCDH, facilitating quality improvement and dental-medical integration.</p><p><strong>Knowledge transfer statement: </strong>Clinicians, payers, health care systems, and policy makers can use the results of this study to guide and assess implementation of the various components of a patient-centered dental home and to support dental-medical integration.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10375154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fit for Purpose? The Suitability of Oral Health Outcome Measures to Inform Policy.","authors":"T M Nguyen, H Rogers, G D Taylor, U Tonmukayakul, C Lin, M Hall, H Calache, C Vernazza","doi":"10.1177/23800844231189997","DOIUrl":"10.1177/23800844231189997","url":null,"abstract":"<p><strong>Knowledge transfer statement: </strong>Oral health research and program evaluation should consider alternative outcome measures for population oral health other than the DMFT index.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10943604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9962651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prioritization, Incentives, and Resource Use for Sustainable Dentistry: The EU PRUDENT Project.","authors":"S Listl, O van Ardenne, J Grytten, D Gyrd-Hansen, H Lang, P Melo, O Nemeth, S Tubert-Jeannin, P Vassallo, E B van Veen, C Vernazza, R Waitzberg, J Winkelmann, N Woods","doi":"10.1177/23800844231189485","DOIUrl":"10.1177/23800844231189485","url":null,"abstract":"<p><strong>Knowledge transfer statement: </strong>The EU PRUDENT project aims to enhance the financing of oral health systems through novel evidence and implementation of better financing solutions together with citizens, patients, providers, and policy makers. The multicountry nature of the project offers unique windows of opportunity for rapid learning and improving within and across various contexts. PRUDENT is anticipated to strengthen capacities for better oral care financing in the EU and worldwide.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10943613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9856109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral Outcomes of a Pragmatic Early Childhood Caries Management Trial.","authors":"C L Lumsden, B L Edelstein, C S Leu, J Zhang, J Levine, H Andrews","doi":"10.1177/23800844231189483","DOIUrl":"10.1177/23800844231189483","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate a preventative behavioral intervention for managing early childhood caries (ECC) in a cohort of high-risk children.</p><p><strong>Methods: </strong>This pragmatic trial of the MySmileBuddy Program (MSB) evaluated preventive behavioral outcomes in a 1-y community health worker-delivered intervention to prevent ECC progression. Pre-/postintervention surveys assessed parent-reported child engagement in therapeutic toothbrushing (i.e., adult-assisted brushing with fluoridated toothpaste twice daily) and caries-related dietary behaviors and barriers. Generalized linear model with identity link for continuous variables and logit link for dichotomous outcomes evaluated pre-/postintervention comparisons and generalized estimating equations accounted for within-participant correlation (α = 0.05).</p><p><strong>Results: </strong>Among 1,130 children with postintervention data, the average age was 3.97 y, 99% were Medicaid insured, and 88% were Hispanic. Most parents (95%) were mothers/grandmothers, married or in a committed partnership (75%), unemployed (62%), and with modest education (80% high school degree or less). The odds of reported therapeutic brushing nearly doubled (<i>n</i> = 864; odds ratio [OR] = 1.79, 95% confidence interval [CI] = 1.46, 2.20, <i>P</i> < 0.001); day and night bottle/sippy cup frequencies dropped 0.29 units (<i>n</i> = 871; 95% CI = -0.37, -0.33, <i>P</i> < 0.001) and 0.22 units (<i>n</i> = 1,130; 95% CI = -0.30, -0.15, <i>P</i> < 0.001); nighttime breastfeeding reduced 0.15 units (<i>n</i> = 870; 95% CI = -0.21, -0.10, <i>P</i> < 0.001); sharing utensils reduced 0.30 units (<i>n</i> = 572; 95% CI = -0.39, -0.21, <i>P</i> < 0.001); not using sugary foods to calm child improved 0.37 units (<i>n</i> = 664; 95% CI = 0.31, 0.44, <i>P</i> < 0.001); odds of eating meals and snacks at a table increased (<i>n</i> = 572; OR = 1.57, 95% CI = 1.28, 1.93, <i>P</i> < 0.001; <i>n</i> = 572; OR = 1.80, 95% CI = 1.50, 2.15, <i>P</i> < 0.001) respectively; and reducing barriers to behaviors improved 0.38 units for toothbrushing (<i>n</i> = 666; 95% CI = 0.31, 0.44, <i>P</i> < 0.001) and 0.33 units for diet (<i>n</i> = 668; 95% CI = 0.29, 0.38, <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Despite limitations inherent to pragmatic trials, significant behavioral changes suggest that MSB yielded an important salutary impact. Forthcoming mediation analyses will explore causal pathways. Findings support integration of MSB's behavior change program in caries management initiatives.</p><p><strong>Knowledge transfer statement: </strong>The results of this study can be used by clinicians, public health leaders, and researchers to inform the development and implementation of community-based, preventative behaviorally focused early childhood caries prevention programs. Study findings may enhance the understanding of the impact of behavioral interventions that engage parents of young children and could l","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11289954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10316606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality-Adjusted Life Year Proxies for Caries in Primary Dentition: A Discrete Choice Experiment.","authors":"T K Lin, D E Arriola Zarate, N Iribarren, H Lindau, F Ramos-Gomez, S A Gansky","doi":"10.1177/23800844221149337","DOIUrl":"10.1177/23800844221149337","url":null,"abstract":"<p><strong>Introduction: </strong>Cost-utility analysis (CUA)-a method to evaluate intervention cost-effectiveness-transforms benefits of alternatives into a measure of quantity and quality of life, such as quality-adjusted life year (QALY), to enable comparison across heterogeneous programs. Measurement challenges prevent directly estimating utilities and calculating QALYs for caries in primary dentition. Proxy disease QALYs are often used as a substitute; however, there lacks quantitative evidence that these proxy diseases are comparable to caries.</p><p><strong>Objective: </strong>To employ a discrete choice experiment (DCE) to quantitatively determine the most comparable proxy disease for different levels of caries in primary dentition.</p><p><strong>Methods: </strong>A cross-sectional DCE survey was administered to respondents (<i>N</i> = 461) who resided in California, were aged ≥18 y, and were primary caretakers for ≥1 child aged 3 to 12 y. Four attributes were included: pain level, disease duration, treatment cost, and family life impacts. Mixed effects logistic regression and conditional logistic regression were used to analyze the survey data.</p><p><strong>Results: </strong>Respondents from the overall sample preferred no pain over mild (odds ratio [OR] = 0.50, <i>P</i> < 0.05), moderate (OR = 0.57, <i>P</i> < 0.05), and severe pain (OR = 0.48, <i>P</i> < 0.05). Acute gastritis (OR = 0.44, <i>P</i> < 0.05), chronic gastritis (OR = 0.31, <i>P</i> < 0.01), and cold sore (OR = 0.38, <i>P</i> < 0.05) were less preferred than stage 1 caries. Acute tonsilitis (OR = 0.43, <i>P</i> < 0.05), acute gastritis (OR = 0.38, <i>P</i> < 0.05), chronic gastritis (OR = 0.26, <i>P</i> < 0.01), and cold sore (OR = 0.33, <i>P</i> < 0.01) were less preferred than stage 2 caries. Chronic gastritis (OR = 0.42,<i>P</i> < 0.05) was less preferred than stage 4 caries.</p><p><strong>Conclusions: </strong>Parents viewed the characteristics of many diseases with similar QALYs differently. Findings suggest that otitis media and its QALY-as commonly used in CUAs-may be a suitable proxy disease and substitute. However, other disease states with slightly different QALYs may be suitable. As such, the recommendation is to consider a range of proxy diseases and their QALYs when conducting a CUA for child caries interventions.</p><p><strong>Knowledge transfer statement: </strong>This study reviews and systematically compares pediatric diseases that are comparable to caries in primary dentition. The findings may inform future research using cost-utility analysis to examine the incremental cost-effectiveness ratio of interventions to prevent and treat caries as compared with an alternative.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10850881/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9333547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Translational Science Conundrum for Junior Investigators.","authors":"S J Calderon, S S Momeni, M O Coker","doi":"10.1177/23800844231151611","DOIUrl":"10.1177/23800844231151611","url":null,"abstract":"<p><strong>Knowledge transfer statement: </strong>The challenges and recommendations outlined in this commentary will serve as steppingstones to process the concepts of translational science, facilitate training for future scientists, and serve as an approach for the early investigators in the field of translational science.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10662188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Oral Function, Protein Intake, and Risk of Sarcopenia: A Scoping Review.","authors":"P J Moynihan, J-L Teo","doi":"10.1177/23800844231157259","DOIUrl":"10.1177/23800844231157259","url":null,"abstract":"<p><strong>Introduction: </strong>Sarcopenia is loss of both muscle mass and function with age and is associated with inadequate protein intake. However, evidence to suggest an association with oral health is less clear.</p><p><strong>Objective: </strong>To scope peer-reviewed published evidence (2000-2022) pertaining to oral function in relation to sarcopenia and/or protein intake in older people.</p><p><strong>Methods: </strong>CINAHL, Embase, PubMed, and Scopus were searched. Included were peer-reviewed studies measuring oral function (e.g., tooth loss, salivary flow masticatory function, strength of muscles of mastication, and tongue pressure) and a measure of protein intake and/or a measure of sarcopenia (appendicular muscle mass <i>and</i> function). Full article screening was conducted by 1 reviewer with a random 10% screened in duplicate by a second reviewer. Relevant content pertaining to study type, country of origin, measures of exposure, and outcomes and key findings was mapped and the balance of data showing a positive versus null association of oral health with outcomes charted.</p><p><strong>Results: </strong>Of 376 studies identified, 126 were screened in full, yielding 32 included texts, of which 29 were original articles. Seven reported intake of protein and 22 reported measures of sarcopenia. Nine distinct oral health exposures were identified, with ≤4 studies relating to any one of these measures. Most data were cross-sectional in nature (27 studies) and from Japan (20 studies). The balance of data showed associations between tooth loss and measures of sarcopenia and protein intake. However, the balance of data pertaining to any association between chewing function, tongue pressure, or indices of oral hypofunction and sarcopenia was mixed.</p><p><strong>Conclusion: </strong>A broad range of oral health measures have been studied in relation to sarcopenia. The balance of data suggests that tooth loss is associated with risk, but data pertaining to the oral musculature and indices of oral hypofunction are mixed.</p><p><strong>Knowledge transfer statement: </strong>The findings of this research will increase awareness among clinicians of the amount and nature of evidence pertaining to the relationship between oral health and risk of compromised muscle mass and function, including data showing that loss of teeth is associated with increased risk of sarcopenia in older people. The findings highlight to researchers the gaps in the evidence and where further research and clarification of the relationship between oral health and risk of sarcopenia is warranted.</p>","PeriodicalId":14783,"journal":{"name":"JDR Clinical & Translational Research","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10725128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10857683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}