JACC. Cardiovascular imaging最新文献

{"title":"Diagnostic Accuracy of Ultra-High-Resolution Photon-Counting Detector Computed Tomography for Detecting Coronary In-Stent Restenosis.","authors":"Simran P Sharma,Judith van der Bie,Annemieke C Ziedses des Plantes,Adriaan Coenen,Marcel L Dijkshoorn,Daniel Bos,Joost Daemen,Nicolas M van Mieghem,Alexander Hirsch,Ricardo P J Budde","doi":"10.1016/j.jcmg.2025.07.009","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.07.009","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"66 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144930404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seeing the Invisible With Ultrasomics: Transforming Myocardial Tissue Characterization or Just Another Layer of Complexity?","authors":"Bjørnar Grenne,Andreas Østvik","doi":"10.1016/j.jcmg.2025.07.011","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.07.011","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"35 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonic Texture Analysis for Predicting Acute Myocardial Infarction.","authors":"Ankush D Jamthikar,Quincy A Hathaway,Kameswari Maganti,Yasmin Hamirani,Sabahat Bokhari,Naveena Yanamala,Partho P Sengupta","doi":"10.1016/j.jcmg.2025.06.018","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.06.018","url":null,"abstract":"BACKGROUNDAcute myocardial infarction (MI) alters cardiomyocyte geometry and architecture, leading to changes in the acoustic properties of the myocardium.OBJECTIVESThis study examines ultrasomics-a novel cardiac ultrasound-based radiomics technique to extract high-throughput pixel-level information from images-for identifying ultrasonic texture and morphologic changes associated with infarcted myocardium.METHODSWe included 684 participants from multisource data: a) a retrospective single-center matched case-control dataset, b) a prospective multicenter matched clinical trial dataset, and c) an open-source international and multivendor dataset. Handcrafted and deep transfer learning-based ultrasomics features from 2- and 4-chamber echocardiographic views were used to train machine learning (ML) models with the use of leave-one-source-out cross-validation for external validation.RESULTSThe ML model showed a higher AUC than transfer learning-based deep features in identifying MI [AUCs: 0.87 [95% CI: 0.84-0.89] vs 0.74 [95% CI: 0.70-0.77]; P < 0.0001]. ML probability was an independent predictor of MI even after adjusting for conventional echocardiographic parameters [adjusted OR: 1.03 [95% CI: 1.01-1.05]; P < 0.0001]. ML probability showed diagnostic value in differentiating acute MI, even in the presence of myocardial dysfunction (averaged longitudinal strain [LS] <16%) (AUC: 0.84 [95% CI: 0.77-0.89]). In addition, combining averaged LS with ML probability significantly improved predictive performance compared with LS alone (AUCs: 0.86 [95% CI: 0.80-0.91] vs 0.80 [95% CI: 0.72-0.87]; P = 0.02). Visualization of ultrasomics features with the use of a Manhattan plot discriminated infarcted and noninfarcted segments (P < 0.001) and facilitated parametric visualization of infarcted myocardium.CONCLUSIONSThis study demonstrates the potential of cardiac ultrasomics to distinguish healthy from infarcted myocardium and highlights the need for validation in diverse populations to define its role and incremental value in myocardial tissue characterization beyond conventional echocardiography.","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"9 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Status and Pending Developments of Robotic Tele-Echocardiography.","authors":"Thomas H Marwick,Edgar M Hidalgo,Leah Wright,Mariadas Roshan,Mats Isaksson","doi":"10.1016/j.jcmg.2025.07.002","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.07.002","url":null,"abstract":"Echocardiography is the gateway to appropriate therapy for many cardiovascular diseases, but access to this test is sometimes challenging. The consequence is that patients in rural and remote areas need to travel for testing, and the resulting time and monetary costs may prove a barrier, especially for hospital inpatients. Delays in obtaining echocardiograms lead to delayed diagnosis and treatment. Technological advances in miniaturization and processing power, and reductions in cost, have enabled diagnostic images to be obtained from inexpensive echocardiography machines. However, imaging by nonexperts is difficult, even with guidance by artificial intelligence. An alternative strategy is to use high-bandwidth, low-latency communication systems to bring the expertise of an expert sonographer to a remote patient by using a robot. Previous work has shown that remote robots are able to reproduce the hand movements performed by sonographers, and multiple types of robot-guided ultrasound examinations have been performed successfully in remote areas. However, despite clear clinical need and ongoing interest, the promise of robotic tele-echocardiography awaits clinical translation. Existing research points toward longer examination times and a need for additional personnel for local supervision of remotely acquired echocardiograms. The efficiencies of longer examinations and more personnel may be worthwhile to facilitate remote access, or within a hospital to avoid sonographer injury, or to improve safety from infection or radiation exposure during structural heart disease interventions. Potentially, autonomous robot-assisted ultrasound may replace the sonographer, by interfacing with artificial intelligence-guided acquisition, although this remains futuristic and uncertain. This paper reviews recent developments in controlling the speed and force of a recently developed robotic system, means of facilitating positioning of the probe, and haptic control. It emphasizes the primary concerns to be imaging time and safety.","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"17 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144791972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Allograft Vasculopathy: Challenges and Opportunities in Noninvasively Diagnosing This Pathology.","authors":"Renée P Bullock-Palmer","doi":"10.1016/j.jcmg.2025.07.004","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.07.004","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2025-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144825709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of Coronary Stent Measurements Using Photon-Counting Detector Computed Tomography: A Comparison With Optical Coherence Tomography.","authors":"Sarah Malik, Doosup Shin, Emma Caron, Rick H J A Volleberg, Koshiro Sakai, Carlos Collet, Evan Shlofmitz, Allen Jeremias, Ziad A Ali, Omar K Khalique","doi":"10.1016/j.jcmg.2025.07.003","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.07.003","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":15.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pericoronary Adipose Tissue Imaging and the Need for Standardized Measurement of Coronary Inflammation","authors":"Charalambos Antoniades MD, PhD,&nbsp;Kenneth Chan MRCP","doi":"10.1016/j.jcmg.2025.06.012","DOIUrl":"10.1016/j.jcmg.2025.06.012","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 8","pages":"Pages 895-898"},"PeriodicalIF":15.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncertain Clinical Relevance of Serial Bone Scintigraphy Findings in Treated Transthyretin Amyloid Cardiomyopathy","authors":"Yousuf Razvi MBChB, BSc ,&nbsp;Aldostefano Porcari MD ,&nbsp;David F. Hutt BApSc ,&nbsp;Jonathan Lazari MBBS, BSc ,&nbsp;Adam Ioannou MBBS, BSc ,&nbsp;Rishi K. Patel MBBS, BSc ,&nbsp;Muhammad Umaid Rauf MBBS ,&nbsp;Tamer Rezk MBBS, PhD ,&nbsp;Oliver Hague BMBCh, BA ,&nbsp;Stefano Filisetti ,&nbsp;Helen J. Lachmann MD ,&nbsp;Ashutosh D. Wechalekar MD ,&nbsp;Aviva Petrie MSc ,&nbsp;Carol J. Whelan MBBS, MD ,&nbsp;Lucia Venneri MD, PhD ,&nbsp;Ana Martinez-Naharro MD, PhD ,&nbsp;Janet A. Gilbertson CSci ,&nbsp;Dorota Rowczenio PhD ,&nbsp;William E. Moody MBBS, PhD ,&nbsp;Richard Steeds MBBS, MD ,&nbsp;Julian D. Gillmore MBBS, MD, PhD","doi":"10.1016/j.jcmg.2025.03.014","DOIUrl":"10.1016/j.jcmg.2025.03.014","url":null,"abstract":"<div><h3>Background</h3><div>Technetium-99m–labeled 3,3-diphosphono-1,2-propanodicarboxylic acid (^99mTc-DPD) scintigraphy is a critical part of the validated nonbiopsy diagnostic algorithm for transthyretin amyloid cardiomyopathy (ATTR-CM). With the advent of novel disease-modifying therapies for ATTR-CM, there is intense interest in establishing the utility of DPD scans as an indicator of treatment response.</div></div><div><h3>Objectives</h3><div>The authors conducted a retrospective multimodality imaging study to determine the utility of ^99mTc-DPD to track treatment response in ATTR-CM.</div></div><div><h3>Methods</h3><div>ATTR-CM patients from the United Kingdom National Amyloidosis Centre who were receiving amyloid-specific disease-modifying therapy (DMT) and underwent pre- and post-treatment ^99mTc-DPD/single-photon emission computed tomography–computed tomography scans were included. Myocardial percentage injected dose (PID), a proposed scintigraphic indicator of cardiac amyloid burden, was measured at baseline and follow-up. Change from baseline in this variable was compared with that of other validated biomarkers of disease severity.</div></div><div><h3>Results</h3><div>A total of 66 patients with ATTR-CM who received DMT underwent serial ^99mTc-DPD scans. At follow-up, with a median time between ^99mTc-DPD scans of 27.5 months (Q1-Q3: 21.9-33.1 months), there was a mean reduction from pre-DMT myocardial PID on ^99mTc-DPD scintigraphy of 1.5 ± 1.5%. No statistically significant correlation between the change in PID at follow-up and change in echocardiographic, biochemical, or cardiac magnetic resonance parameters was identified. Discordance in which there was an improvement on follow-up ^99mTc-DPD scintigraphy despite disease progression was observed in 28/66 patients (42.4%).</div></div><div><h3>Conclusions</h3><div>Our study indicates a poor correlation between reduction in ^99mTc-DPD uptake at follow-up and numerous established biomarkers of ATTR-CM treatment response. Changes in DPD uptake in ATTR-CM patients receiving DMT should be interpreted with caution.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 8","pages":"Pages 899-908"},"PeriodicalIF":15.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Pericoronary Adipose Attenuation With Major Adverse Cardiovascular Events and High-Risk Plaque","authors":"Neville Tan MBBS, MPH ,&nbsp;Thomas H. Marwick MBBS, MPH, PhD ,&nbsp;Damini Dey MD ,&nbsp;William Chan MBBS, PhD ,&nbsp;Nitesh Nerlekar MBBS, MPH, PhD","doi":"10.1016/j.jcmg.2025.04.008","DOIUrl":"10.1016/j.jcmg.2025.04.008","url":null,"abstract":"<div><h3>Background</h3><div>The characterization of pericoronary adipose tissue (PCAT) attenuation may provide adjunctive prognostic information to coronary evaluation at coronary computed tomography angiography. However, heterogeneity in measurement methodologies has led to uncertainties regarding its clinical applicability.</div></div><div><h3>Objectives</h3><div>This systematic review and meta-analysis explores the impact of measurement methodology on the association between PCAT and major adverse cardiac events (MACE) and high-risk plaque (HRP).</div></div><div><h3>Methods</h3><div>Studies linking PCAT to MACE and HRP were searched in online databases. Quantitative meta-analysis was only performed where univariable HR estimates were reported, and random effects modelling with 95% CIs are reported. Qualitative synthesis was performed where multivariable estimates were reported.</div></div><div><h3>Results</h3><div>There were 17 studies (N = 10,482) included. Quantitative analysis was performed in 8,396 patients, all with stable coronary artery disease; elevated right coronary artery (RCA)–PCAT attenuation was associated with MACE (HR: 1.22 [95% CI: 1.08-1.38]; <em>P =</em> 0.001), with weak significance in left circumflex–PCAT (HR: 1.03 [95% CI: 1.01-1.05]; <em>P =</em> 0.014), and left anterior descending artery–PCAT did not meet significance (HR: 1.01 [95% CI: 0.98-1.05]; <em>P =</em> 0.47). No quantitative synthesis was possible for association with HRP. Qualitatively, studies have shown a positive and significant association with RCA-PCAT and HRP (HR range: 1.03-5.62). Although studies adjusted for different risk modifiers in multivariable models, a positive association was found despite different measurement methodology (mean PCAT, fat attenuation index) and minor differences in study-defined cutoffs for elevated RCA-PCAT attenuation.</div></div><div><h3>Conclusions</h3><div>Although the strength of associations varied by measurement technique, PCAT is associated with MACE and high-risk plaque.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 8","pages":"Pages 884-894"},"PeriodicalIF":15.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144603971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One Score, Many Paths","authors":"Ioannis Skalidis MD, PhD,&nbsp;Eirini Beneki MD,&nbsp;Anastasios Apostolos MD,&nbsp;Georgios Tzimas MD,&nbsp;Panagiotis Antiochos MD","doi":"10.1016/j.jcmg.2025.05.011","DOIUrl":"10.1016/j.jcmg.2025.05.011","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 8","pages":"Page 937"},"PeriodicalIF":15.2,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}