{"title":"Carotid Artery Atherosclerosis Is a Marker for Risk of Stroke and Cardiac Death","authors":"Christopher K. Zarins MD","doi":"10.1016/j.jcmg.2024.10.002","DOIUrl":"10.1016/j.jcmg.2024.10.002","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 1","pages":"Pages 90-92"},"PeriodicalIF":12.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142949283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Revisiting Diagnostic Criteria for Hypertrophic Cardiomyopathy in Hypertensive and Nonhypertensive Patients","authors":"Yong-Huai Wang MD, PhD, Chun-Yan Ma MD, PhD","doi":"10.1016/j.jcmg.2023.11.019","DOIUrl":"10.1016/j.jcmg.2023.11.019","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"17 12","pages":"Page 1517"},"PeriodicalIF":12.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vascular Remodeling in Coronary Microvascular Dysfunction","authors":"Carlos Collet MD, PhD , Koshiro Sakai MD, PhD , Takuya Mizukami MD, PhD , Hirofumi Ohashi MD, PhD , Frederic Bouisset MD , Serena Caglioni MD , Lieven van Hoe MD , Emanuele Gallinoro MD, PhD , Dario Tino Bertolone MD , Sofie Pardaens MSc, PhD , Sofie Brouwers MD, PhD , Tatyana Storozhenko MD , Ruiko Seki MD , Daniel Munhoz MD, PhD , Atomu Tajima MD , Dimitri Buytaert MsC , Marc Vanderheyden MD , Eric Wyffels MD , Jozef Bartunek MD, PhD , Jeroen Sonck MD, PhD , Bernard De Bruyne MD, PhD","doi":"10.1016/j.jcmg.2024.07.018","DOIUrl":"10.1016/j.jcmg.2024.07.018","url":null,"abstract":"<div><h3>Background</h3><div>Approximately one-half of the patients with angina and nonobstructive coronary artery disease (ANOCA) have evidence of coronary microvascular dysfunction (CMD).</div></div><div><h3>Objectives</h3><div>This study aims to characterize patients with ANOCA by measuring their minimal microvascular resistance and to examine the pattern of vascular remodeling associated with these measurements.</div></div><div><h3>Methods</h3><div>The authors prospectively included patients with ANOCA undergoing continuous thermodilution assessment. Lumen volume and vessel-specific myocardial mass were quantified using coronary computed tomography angiography (CTA). CMD was defined as coronary flow reserve <2.5 and high minimal microvascular resistance as >470 WU.</div></div><div><h3>Results</h3><div>A total of 153 patients were evaluated; 68 had CMD, and 22 of them showed high microvascular resistance. In patients with CMD, coronary flow reserve was 1.9 ± 0.38 vs 3.2 ± 0.81 in controls (<em>P <</em> 0.001). Lumen volume was significantly correlated with minimal microvascular resistance (r = −0.59 [95% CI: −0.45 to −0.71]; <em>P <</em> 0.001). In patients with CMD and high microvascular resistance, lumen volume was 40% smaller than in controls (512.8 ± 130.3 mm<sup>3</sup> vs 853.2 ± 341.2 mm<sup>3</sup>; <em>P <</em> 0.001). Epicardial lumen volume assessed by coronary CTA was independently associated with minimal microvascular resistance (<em>P <</em> 0.001). The predictive capacity of lumen volume from coronary CTA for detecting high microvascular resistance showed an area under the curve of 0.79 (95% CI: 0.69-0.88).</div></div><div><h3>Conclusions</h3><div>Patients with CMD and high minimal microvascular resistance have smaller epicardial vessels than those without CMD. Coronary CTA detected high minimal microvascular resistance with very good diagnostic capacity. Coronary CTA could potentially aid in the diagnostic pathway for patients with ANOCA.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"17 12","pages":"Pages 1463-1476"},"PeriodicalIF":12.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142287688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}