Philipp M Doldi, Lukas Stolz, Mirjam G Wild, Kaspar Volz, Thomas J Stocker, Ludwig T Weckbach, Hannah Kempton, Sebastian Rosch, Felix Rudolph, Bjoern Goebel, Benedikt Koell, Philipp von Stein, Wolfgang Rottbauer, Tienush Rassaf, Harald Beucher, Martin Kraus, Mohammad Kassar, Tobias Geisler, Andreas Rück, Joao Ferreira-Martins, Stefan Toggweiler, Paula Sagmeister, Dirk Westermann, Michael Näbauer, Magnus Settergren, Sam Dawkins, Tobias Kister, Fabien Praz, Marc Vorpahl, Mathias H Konstandin, Peter Luedike, Mirjam Kessler, Christos Iliadis, Daniel Kalbacher, Philip Lauten, Muhammed Gerçek, Christian Besler, Steffen Massberg, Philipp Lurz, Jörg Hausleiter
{"title":"Impact of Inflow Gradients on Mortality and Heart Failure Hospitalizations Following Transcatheter Tricuspid Valve Edge-to-Edge Repair: Insights from the PASTE Registry.","authors":"Philipp M Doldi, Lukas Stolz, Mirjam G Wild, Kaspar Volz, Thomas J Stocker, Ludwig T Weckbach, Hannah Kempton, Sebastian Rosch, Felix Rudolph, Bjoern Goebel, Benedikt Koell, Philipp von Stein, Wolfgang Rottbauer, Tienush Rassaf, Harald Beucher, Martin Kraus, Mohammad Kassar, Tobias Geisler, Andreas Rück, Joao Ferreira-Martins, Stefan Toggweiler, Paula Sagmeister, Dirk Westermann, Michael Näbauer, Magnus Settergren, Sam Dawkins, Tobias Kister, Fabien Praz, Marc Vorpahl, Mathias H Konstandin, Peter Luedike, Mirjam Kessler, Christos Iliadis, Daniel Kalbacher, Philip Lauten, Muhammed Gerçek, Christian Besler, Steffen Massberg, Philipp Lurz, Jörg Hausleiter","doi":"10.1016/j.jcmg.2026.01.011","DOIUrl":"https://doi.org/10.1016/j.jcmg.2026.01.011","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":15.2,"publicationDate":"2026-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Waseem Hijazi, Joel Lenell, Kajetan Grodecki, Jacek Kwiecinski, Robert J H Miller, Daniel S Berman, David E Newby, Michelle C Williams, Piotr J Slomka, Damini Dey
{"title":"AI-Derived Ischemia Score From Coronary CT Angiography Predicts Myocardial Infarctions: Insights From the SCOT-HEART Trial.","authors":"Waseem Hijazi, Joel Lenell, Kajetan Grodecki, Jacek Kwiecinski, Robert J H Miller, Daniel S Berman, David E Newby, Michelle C Williams, Piotr J Slomka, Damini Dey","doi":"10.1016/j.jcmg.2026.01.004","DOIUrl":"https://doi.org/10.1016/j.jcmg.2026.01.004","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":15.2,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eswar Sivaraj MS , Lasse Lovstakken PhD , Raphaela Corney BMedRes (Hons) , Solveig Fadnes PhD , Torvald Espeland MD , Kristoffer Andresen MD , Thomas H. Marwick MBBS, PhD, MPH
{"title":"Mechanical Wave Analysis at High Frame-Rate Echocardiography","authors":"Eswar Sivaraj MS , Lasse Lovstakken PhD , Raphaela Corney BMedRes (Hons) , Solveig Fadnes PhD , Torvald Espeland MD , Kristoffer Andresen MD , Thomas H. Marwick MBBS, PhD, MPH","doi":"10.1016/j.jcmg.2025.08.006","DOIUrl":"10.1016/j.jcmg.2025.08.006","url":null,"abstract":"<div><h3>Background</h3><div>High–frame rate echocardiography can identify naturally occurring mechanical waves (MWs). As the velocity of MWs is related to tissue properties, this methodology could solve a fundamental shortcoming of echocardiography. However, to be useful clinically, there would need to be limited overlap between the normal range of MWs and measurements associated with pathology such as left ventricular dysfunction and ischemic heart disease.</div></div><div><h3>Objectives</h3><div>This study aims to evaluate the feasibility, key determinants, and normal ranges of MWs in asymptomatic people and in patients with cardiac pathology.</div></div><div><h3>Methods</h3><div>Asymptomatic participants were recruited from a community-based heart failure surveillance program. Clinical evaluation, 6-minute walk test, and echocardiography with specialized high–frame rate imaging were performed. MW signals from atrial kick (AK), aortic valve closure (AVC), and mitral valve closure (MVC) were acquired from parasternal long-axis (PLAX) and apical 4-chamber (A4C) windows. Measurements were averaged across 3 cycles using automated and manual methods, and outliers were removed (AVC >9 m/s, MVC >9 m/s, and AK >7 m/s). Participants were classified into normal and abnormal groups on the basis of echocardiographic and clinical parameters.</div></div><div><h3>Results</h3><div>Of the 239 participants, manual measurement was feasible in 80% for AK, 77% for AVC, and 77% for MVC MWs in the PLAX view and in 91%, 85%, and 62% in the A4C view. Manual measurements were more feasible than automated measurements. Clinical and echocardiographic markers of hemodynamic status and cardiac function had little or no association with MW velocities. Poor agreement was noted between A4C and PLAX MVC signals, especially with high-velocity measurements. In 66 participants without overt CVD, MW velocities in the PLAX view for AVC, MVC, and AK were 3.91 ± 1.82 m/s, 3.58 ± 1.67 m/s, and 1.77 ± 1.10 m/s. In the A4C view, these were 4.09 ± 1.54 m/s, 5.63 ± 1.61 m/s, and 1.24 ± 0.38 m/s, respectively. These values were generally slightly higher in 103 asymptomatic people with subclinical dysfunction. Only AK measurements were significantly different between patients with normal and abnormal findings on echocardiography. There was little bias within and between observers, but limits of agreement were wide for all measures.</div></div><div><h3>Conclusions</h3><div>MW measurement, especially AK, is a feasible adjunct to standard echocardiography. However, the normal ranges are wide, even among participants with otherwise normal studies. MW velocities do not seem to be abnormal in subclinical dysfunction.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 2","pages":"Pages 149-162"},"PeriodicalIF":15.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144955004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nobuyuki Kagiyama MD, PhD , Márton Tokodi MD, PhD , Quincy A. Hathaway MD, PhD , Rima Arnaout MD , Rhodri Davies MD, PhD , Damini Dey PhD , Nicolas Duchateau PhD , Alan G. Fraser BSc, MB, ChB , Shinichi Goto MD, PhD , Ankush D. Jamthikar PhD , Carolyn S.P. Lam MBBS, PhD , Evangelos K. Oikonomou MD, DPhil , David Ouyang MD , Ambarish Pandey MD, MSCS , Timothy J. Poterucha MD , Zahra Raisi-Estabragh PhD , Jordan B. Strom MD, MSc , Qiang Zhang PhD , Naveena Yanamala PhD , Partho P. Sengupta MD, DM
{"title":"PRIME 2.0: Proposed Requirements for Cardiovascular Imaging-Related Multimodal-AI Evaluation","authors":"Nobuyuki Kagiyama MD, PhD , Márton Tokodi MD, PhD , Quincy A. Hathaway MD, PhD , Rima Arnaout MD , Rhodri Davies MD, PhD , Damini Dey PhD , Nicolas Duchateau PhD , Alan G. Fraser BSc, MB, ChB , Shinichi Goto MD, PhD , Ankush D. Jamthikar PhD , Carolyn S.P. Lam MBBS, PhD , Evangelos K. Oikonomou MD, DPhil , David Ouyang MD , Ambarish Pandey MD, MSCS , Timothy J. Poterucha MD , Zahra Raisi-Estabragh PhD , Jordan B. Strom MD, MSc , Qiang Zhang PhD , Naveena Yanamala PhD , Partho P. Sengupta MD, DM","doi":"10.1016/j.jcmg.2025.08.004","DOIUrl":"10.1016/j.jcmg.2025.08.004","url":null,"abstract":"<div><div>The PRIME (Proposed Requirements for Cardiovascular Imaging–Related Machine Learning Evaluation) 2.0 checklist is an updated, domain-specific framework designed to standardize the development, evaluation, and reporting of artificial intelligence (AI) applications in cardiovascular imaging. This update specifically responds to rapid advances from traditional machine learning to deep learning, large language models, and multimodal generative AI. The updated checklist was developed through a modified Delphi process by an international panel of clinical and technical experts. In contrast to general AI reporting guidelines, it delivers detailed, practical recommendations on all critical aspects of AI research and builds upon the original 7-domain framework by incorporating cardiovascular imaging–specific complexities such as cardiac motion, imaging artifacts, and interobserver variability. By promoting transparency and rigor, PRIME 2.0 can serve as a vital resource for researchers, clinicians, peer reviewers, and journal editors working at the forefront of AI in cardiovascular imaging.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 2","pages":"Pages 225-251"},"PeriodicalIF":15.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephen J. Hankinson MD, Akshay S. Desai MD, MPH, Garrick C. Stewart MD, MPH, Neal K. Lakdawala MD, MS, Michael M. Givertz MD, Usha B. Tedrow MD, MS, William H. Sauer MD, Ron Blankstein MD, Marcelo F. Di Carli MD, Sanjay Divakaran MD, MPH
{"title":"Patterns of Nonspecific Myocardial FDG Uptake in Patients Without Sarcoidosis With Normal CMR","authors":"Stephen J. Hankinson MD, Akshay S. Desai MD, MPH, Garrick C. Stewart MD, MPH, Neal K. Lakdawala MD, MS, Michael M. Givertz MD, Usha B. Tedrow MD, MS, William H. Sauer MD, Ron Blankstein MD, Marcelo F. Di Carli MD, Sanjay Divakaran MD, MPH","doi":"10.1016/j.jcmg.2025.09.005","DOIUrl":"10.1016/j.jcmg.2025.09.005","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 2","pages":"Pages 288-290"},"PeriodicalIF":15.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}