JACC. Cardiovascular imaging最新文献

{"title":"Microplastics and Nanoplastics and Optical Coherence Tomography–Defined Plaque Instability in Acute Coronary Syndrome","authors":"Yunxiao Yang MD, PhD, Hehe Cui MD, PhD, Lin Wang MD, PhD, Zhiyong Du PhD, Yinjian Yang MD, PhD, Sheng Liu MD, PhD, Ming Zhang MD, PhD, Chen Li MD, PhD, Wei Li PhD, Xiubin Yang MD, PhD, Wei Luo MD, PhD, Hai Gao MD, PhD","doi":"10.1016/j.jcmg.2026.04.008","DOIUrl":"10.1016/j.jcmg.2026.04.008","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 9","pages":"Pages 1156-1158"},"PeriodicalIF":19.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148257526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Do Indexed Aortic Diameters Provide Individualized Precision Risk Stratification?","authors":"Arturo Evangelista MD, PhD, Hector I. Michelena MD","doi":"10.1016/j.jcmg.2026.06.003","DOIUrl":"10.1016/j.jcmg.2026.06.003","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 9","pages":"Pages 1107-1109"},"PeriodicalIF":19.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Concomitant Mitral Regurgitation in Moderate Aortic Stenosis","authors":"El-Moatasem Gabr MD, MSc,&nbsp;Mianli Xiao PhD,&nbsp;Mujtaba Saeed MD,&nbsp;Amr Darwish MD,&nbsp;Akila Bersali MD,&nbsp;Aneesh Dhore-Patil MD,&nbsp;Thammarak Songsangjinda MD,&nbsp;Edward A. Graviss PhD, MPH,&nbsp;Neal S. Kleiman MD,&nbsp;Maan Malahfji MD,&nbsp;Dipan J. Shah MD","doi":"10.1016/j.jcmg.2026.04.015","DOIUrl":"10.1016/j.jcmg.2026.04.015","url":null,"abstract":"<div><h3>Background</h3><div>Patients with moderate aortic stenosis (AS) and concomitant mitral regurgitation (MR) often present with symptoms despite neither lesion individually reaching intervention thresholds. The clinical impact of this dual valvular disease remains a knowledge gap.</div></div><div><h3>Objectives</h3><div>The aims of this study were to evaluate the effect of concomitant MR on cardiac remodeling and clinical outcomes in patients with moderate AS using cardiac magnetic resonance (CMR) and to compare with isolated moderate and severe AS.</div></div><div><h3>Methods</h3><div>A total of 742 patients with at least moderate AS on CMR (422 with moderate AS, 320 with severe AS) were studied. Patients were stratified by AS severity and MR burden. Remodeling parameters, symptoms, and outcomes, including cardiovascular death and heart failure hospitalization, were analyzed. Multivariable Cox models identified covariates associated with outcomes.</div></div><div><h3>Results</h3><div>Among 422 patients with moderate AS, 76 had moderate or greater MR. Compared with isolated moderate AS, combined AS and MR was associated with higher symptom burden (80.3% in NYHA functional classes II-IV), more pronounced remodeling (larger indexed left ventricular volumes, lower left ventricular ejection fractions), and reduced aortic forward flow. Over a median 1.8 years, coexisting moderate or greater MR was independently associated with cardiovascular death or heart failure hospitalization (adjusted HR: 1.86; 95% CI: 1.31-2.65; <em>P</em> &lt; 0.001). This risk was more apparent in the low-flow subgroup (stroke volume index ≤35 mL/m²), whereas in normal-flow patients, there was a trend toward increased risk that did not reach statistical significance. Outcomes in moderate AS with moderate or greater MR were worse than in isolated severe AS and comparable with severe AS populations meeting criteria for intervention.</div></div><div><h3>Conclusions</h3><div>Patients with moderate AS and MR constitute a high-risk subgroup with high symptom burden, adverse cardiac remodeling, and poor clinical outcomes. Risk appears more pronounced in the setting of reduced forward flow (stroke volume index ≤35 mL/m²). CMR enables the quantitative assessment of dual valvular burden and may improve risk stratification. These findings highlight a therapeutic gap and support studies of earlier intervention in this high-risk subgroup.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 9","pages":"Pages 1058-1073"},"PeriodicalIF":19.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13262784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148217867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Capturing Residual Inflammatory and Cardiometabolic Risk Beyond Low-Density Lipoprotein Cholesterol","authors":"Kenneth Chan MRCP,&nbsp;Mark Colin Gissler MD","doi":"10.1016/j.jcmg.2026.06.006","DOIUrl":"10.1016/j.jcmg.2026.06.006","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 9","pages":"Pages 1090-1093"},"PeriodicalIF":19.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing CT Diagnosis of Bioprosthetic Valve Thrombosis","authors":"Catalina Paraschiv,Hayat Memis,Giordano M. Pugliesi,Serban M. Balanescu,Jeremy D. Collins,Vuysile T. Nkomo,Bas L. Kietselaer,Sorin V. Pislaru,Thomas A. Foley","doi":"10.1016/j.jcmg.2026.07.007","DOIUrl":"https://doi.org/10.1016/j.jcmg.2026.07.007","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"355 1","pages":""},"PeriodicalIF":14.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148893804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TRISCEND II","authors":"Anna Sannino MD, PhD,&nbsp;Paul A. Grayburn MD,&nbsp;Susheel K. Kodali MD,&nbsp;Philipp Lurz MD, PhD,&nbsp;Vinod H. Thourani MD,&nbsp;Moody Makar MD,&nbsp;Christiane Haeffele MD,&nbsp;Jyothy Puthumana MD,&nbsp;James Lee MD,&nbsp;Peter Flueckiger MD,&nbsp;Scott Chadderdon MD,&nbsp;Ratnasari Padang MBBS, PhD,&nbsp;Nishant K. Sekaran MD,&nbsp;Terri Stewart-Dehner MD,&nbsp;Jörg Ender MD,&nbsp;Konstantinos Koulogiannis MD,&nbsp;Mohamed Morsy MD,&nbsp;Rhonda Miyasaka MD,&nbsp;Benjamin Havens MD,&nbsp;Ivy Ku MD,&nbsp;Rebecca T. Hahn MD","doi":"10.1016/j.jcmg.2026.05.019","DOIUrl":"10.1016/j.jcmg.2026.05.019","url":null,"abstract":"<div><h3>Background</h3><div>The TRISCEND II (EVOQUE Transcatheter Tricuspid Valve Replacement: Pivotal Clinical Investigation of Safety and Clinical Efficacy Using a Novel Device) trial demonstrated clinical benefits for transcatheter tricuspid valve replacement (TTVR) with the EVOQUE System over medical therapy for the primary safety and effectiveness endpoint to 1 year.</div></div><div><h3>Objectives</h3><div>The authors report echocardiographic outcomes at 1 year for the randomized cohort and evaluate hemodynamic and structural changes.</div></div><div><h3>Methods</h3><div>The multicenter, prospective TRISCEND II trial enrolled 400 patients with severe, symptomatic tricuspid regurgitation (TR) and randomized them in a 2:1 ratio to TTVR (n = 267) or medical therapy (control) (n = 133). The secondary echocardiographic endpoint was reduction in TR severity from baseline to discharge. Echocardiograms were evaluated by an independent echocardiographic core laboratory.</div></div><div><h3>Results</h3><div>All patients had severe TR at baseline; at discharge, 95.5% of patients who underwent TTVR had mild TR. On paired analysis from baseline to 1 year, 95.3% of patients who underwent TTVR and 2.3% of control patients achieved mild TR. Between baseline and 1 year, the mean inferior vena cava diameter decreased significantly more for patients who underwent TTVR (normal breathing <em>P</em> &lt; 0.001; forced inhalation <em>P</em> = 0.038). Patients who underwent TTVR experienced greater improvements in diastolic right ventricular (RV) size (<em>P</em> &lt; 0.05) and larger decreases in RV systolic function (<em>P</em> &lt; 0.001), consistent with reduced preload from TR reduction. RV stroke volume and cardiac output increased significantly in patients who underwent TTVR (<em>P</em> &lt; 0.001) but not in control patients.</div></div><div><h3>Conclusions</h3><div>One-year echocardiographic outcomes from the TRISCEND II trial demonstrated that near elimination of TR following TTVR is associated with reduced venous congestion, RV reverse remodeling, and significant improvements in forward stroke volume and cardiac output. (EVOQUE Transcatheter Tricuspid Valve Replacement: Pivotal Clinical Investigation of Safety and Clinical Efficacy Using a Novel Device [TRISCEND II Pivotal Trial]; <span><span>NCT04482062</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 9","pages":"Pages 1027-1039"},"PeriodicalIF":19.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148476163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When “Incremental Prediction” Does Not Translate to Incremental Management","authors":"Shankar Biswas MD,&nbsp;Yashasvi Srivastava MD,&nbsp;Dileep Raja Kuraku MD,&nbsp;Shailesh Jagdish Patil MD, DM,&nbsp;Raja Kollu MD","doi":"10.1016/j.jcmg.2026.05.024","DOIUrl":"10.1016/j.jcmg.2026.05.024","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 9","pages":"Pages 1163-1164"},"PeriodicalIF":19.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148912134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Incidence of Tricuspid Regurgitation Following Cardiac Implantable Electronic Device Implantation","authors":"María D. Valderrama-Achury MD,&nbsp;Camilo A. Rodríguez-García MD,&nbsp;Yilmar A. Meza-Gonzalez MD,&nbsp;Gabriel Salazar MD,&nbsp;Juan F. Vasquez-Rodriguez MD,&nbsp;Claudia P. Jaimes MD,&nbsp;Camilo A. Calderon-Miranda MD,&nbsp;Hector M. Medina MD, MPH,&nbsp;Luis C. Saenz MD,&nbsp;Maria I. Zorro RN,&nbsp;Juan C. Duran RN,&nbsp;Carlos E. Guerrero-Chalela MD,&nbsp;Rebecca T. Hahn MD,&nbsp;Julian Gelves-Meza MD","doi":"10.1016/j.jcmg.2026.04.012","DOIUrl":"10.1016/j.jcmg.2026.04.012","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 9","pages":"Pages 1153-1155"},"PeriodicalIF":19.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148030687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seeing the Unseen","authors":"Jadranka Stojanovska MD, MS,&nbsp;Charlotte Manisty MB MS, PhD","doi":"10.1016/j.jcmg.2026.05.010","DOIUrl":"10.1016/j.jcmg.2026.05.010","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 9","pages":"Pages 1055-1057"},"PeriodicalIF":19.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148342360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Learning for Cardiac Image Analysis","authors":"Joske L. van der Zande MSc,&nbsp;Laura Alvarez-Florez MSc,&nbsp;Rick H.J.A. Volleberg MD,&nbsp;Carolina Brás MSc,&nbsp;Dimitrios Karkalousos PhD,&nbsp;Robin Nijveldt MD, PhD,&nbsp;Niels van Royen MD, PhD,&nbsp;Tim Leiner MD, PhD,&nbsp;Nadieh Khalili PhD,&nbsp;Geert Litjens PhD,&nbsp;Jos Thannhauser PhD,&nbsp;Ivana Išgum PhD","doi":"10.1016/j.jcmg.2026.03.007","DOIUrl":"10.1016/j.jcmg.2026.03.007","url":null,"abstract":"<div><div>Deep learning (DL) continues to advance cardiac image analysis with increasingly sophisticated methodologies. Although convolutional neural networks laid the foundation for DL, emerging methods including graph neural networks, transformers, implicit neural representations, generative adversarial networks, and foundation models enable enhanced anatomical and functional modeling, image generation, and multimodal integration. Graph neural networks enable non-Euclidean data representations that preserve anatomical structure; transformers improve sequence modeling in dynamic imaging; and implicit neural representations introduce continuous spatial representations for more accurate reconstructions. Generative adversarial networks enhance image generation, noise reduction, and cross-modality synthesis adaptation, while foundation models introduce a unified, generalizable framework capable of adapting across diverse imaging tasks. This review discusses these key innovations of DL in cardiac imaging, their implications, and their challenges as well as potential future directions in the field, such as clinical validation trials.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"19 9","pages":"Pages 1122-1143"},"PeriodicalIF":19.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147815387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}