JACC. Cardiovascular imaging最新文献

{"title":"Mid- to Late-Life Traditional Cardiovascular Risk Factor Exposure and Zero Coronary Artery Calcium","authors":"Frances M. Wang PhD, MS ,&nbsp;Shoshana H. Ballew PhD ,&nbsp;Aaron R. Folsom MD ,&nbsp;Lynne E. Wagenknecht DrPH ,&nbsp;Candace M. Howard MD, PhD ,&nbsp;Josef Coresh MD, PhD ,&nbsp;Matthew J. Budoff MD ,&nbsp;Michael J. Blaha MD, MPH ,&nbsp;Kunihiro Matsushita MD, PhD","doi":"10.1016/j.jcmg.2025.01.019","DOIUrl":"10.1016/j.jcmg.2025.01.019","url":null,"abstract":"<div><h3>Background</h3><div>Our understanding of traditional atherosclerotic risk factors is based predominantly on one-time measurements and associations with adverse cardiovascular outcomes.</div></div><div><h3>Objectives</h3><div>The aim of this study was to evaluate the contribution of mid- to late-life cumulative risk factor exposure to healthy arterial aging, represented by a persistent coronary artery calcium (CAC) score of zero.</div></div><div><h3>Methods</h3><div><span>Among 2,044 community-dwelling, participants free of coronary heart disease from the ARIC (Atherosclerosis Risk in Communities) study, the associations of ∼30-year time-weighted average mid- to late-life (starting at a median age of 49 years in 1987-1989) traditional atherosclerotic risk factors (cholesterol, </span>systolic blood pressure, fasting glucose, and smoking) with late-life (median age 80 years in 2018-2019) CAC 0 were evaluated.</div></div><div><h3>Results</h3><div>A total of 204 participants (10.0%) had CAC 0, and they tended to have more favorable mid- to late-life average risk factor profiles than those with CAC: lower total cholesterol<span>, especially &lt;160 mg/dL; lower systolic blood pressure, especially &lt;125 mm Hg; and higher high-density lipoprotein cholesterol, especially &gt;45 mg/dL. The association was less evident for fasting glucose, with no increased probability of CAC 0 at &lt;95 mg/dL. Never smoking was associated with a 5.7 (95% CI: 2.3-16.7) times greater odds of CAC 0 vs smoking throughout mid- to late-life. Within sex-race groups, average modifiable risk factors predicted substantial differences in CAC 0 probability (eg, for a Black woman, 53% vs 0.4% for a low vs high risk factor profile, respectively).</span></div></div><div><h3>Conclusions</h3><div>Favorable average risk factor profiles at mid- to late-life were associated with a greater probability of CAC 0 at older age. These results highlight the importance of maintaining a healthy risk factor profile from mid- to late-life, with implications for public health promotion and policy.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages 973-984"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tricuspid Valve Transcatheter Edge-to-Edge Repair in Challenging Scenarios","authors":"Lucy M. Safi DO ,&nbsp;Gilbert H.L. Tang MD, MSc, MBA ,&nbsp;Parasuram Krishnamoorthy MD ,&nbsp;Annapoorna S. Kini MD ,&nbsp;Samin K. Sharma MD ,&nbsp;Sahil Khera MD, MPH ,&nbsp;Stamatios Lerakis MD, PhD","doi":"10.1016/j.jcmg.2025.05.013","DOIUrl":"10.1016/j.jcmg.2025.05.013","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages 1042-1052"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144488073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Cardiovascular Health and Time Lived With Zero Coronary Artery Calcium","authors":"Nilay S. Shah MD, MPH ,&nbsp;Xiaoning Huang PhD ,&nbsp;Natalie A. Cameron MD ,&nbsp;Lucia C. Petito PhD ,&nbsp;Bo Zhou PhD ,&nbsp;Norrina B. Allen PhD ,&nbsp;Mercedes R. Carnethon PhD ,&nbsp;Philip Greenland MD ,&nbsp;Donald M. Lloyd-Jones MD, ScM ,&nbsp;Sadiya S. Khan MD, MSc","doi":"10.1016/j.jcmg.2025.05.022","DOIUrl":"10.1016/j.jcmg.2025.05.022","url":null,"abstract":"<div><h3>Background</h3><div>Zero coronary artery calcium (CAC) is robustly associated with lower risk of cardiovascular disease (CVD). Factors associated with greater time lived with zero CAC are not well understood.</div></div><div><h3>Objectives</h3><div>This study aims to evaluate the association of cardiovascular health (CVH) and time lived with zero CAC.</div></div><div><h3>Methods</h3><div>In MESA (Multi-Ethnic Study of Atherosclerosis), participants who had zero CAC at baseline and were followed up to 10 years, restricted mean survival time since study entry lived with zero CAC was estimated by baseline CVH (high, intermediate, low), stratified by sex and age (45-64 years and 65-84 years).</div></div><div><h3>Results</h3><div>Among 3,416 participants with zero CAC at baseline (63% female, age 58 ± 9 years at baseline, CVH score 8.8 ± 2.1), the years since study entry lived with zero CAC was 4.9 ± 3.5 years. Women with high vs low CVH lived on average 6.6 years (95% CI: 6.4-6.8 years) vs 5.6 years (95% CI: 5.3-5.8 years) with zero CAC (<em>P &lt;</em> 0.01). Men with high vs low CVH lived 6.4 years (95% CI: 5.9-6.9 years) vs 5.5 years (95% CI: 5.1-5.9 years) with zero CAC (<em>P =</em> 0.01). Participants aged 45 to 64 years with high vs low CVH lived 7.4 years (95% CI: 7.1-7.6 years) vs 5.9 years (95% CI: 5.7-6.2 years) with zero CAC (<em>P &lt;</em> 0.01). Participants aged 65 to 84 years at baseline with high vs low CVH lived a similar duration with zero CAC (5.1 years [95% CI: 4.5-5.7 years] vs 4.9 years [95% CI: 4.6-5.2 years]) with zero CAC (<em>P =</em> 0.65).</div></div><div><h3>Conclusions</h3><div>High CVH was associated with longer time lived with zero CAC. Maintaining high CVH early in midlife may reduce risk of CVD as measured by CAC onset.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages 985-993"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144693420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonischemic Septal Fibrosis in Functional Tricuspid Regurgitation Provides Incremental Stratification of Adverse Remodeling and Prognosis","authors":"Pablo Villar-Calle MD ,&nbsp;Varun Pai BA ,&nbsp;Robert S. Zhang MD ,&nbsp;Mahniz Reza BA ,&nbsp;Lily Jin BS ,&nbsp;Rachel Axman MD ,&nbsp;Zachary Falk MD ,&nbsp;Giorgia Falco MD ,&nbsp;Arindam RoyChoudhury PhD ,&nbsp;Shmuel Chen MD PhD ,&nbsp;Bobak Mosadegh PhD ,&nbsp;Susheel K. Kodali MD ,&nbsp;Omar K. Khalique MD ,&nbsp;Evelyn M. Horn MD ,&nbsp;Jonathan W. Weinsaft MD ,&nbsp;Jiwon Kim MD","doi":"10.1016/j.jcmg.2025.03.015","DOIUrl":"10.1016/j.jcmg.2025.03.015","url":null,"abstract":"<div><h3>Background</h3><div><span>Functional tricuspid regurgitation (TR) arises from impaired valve integrity resulting from contractile dysfunction, chamber dilation, or myocardial tissue alterations. Whereas right ventricular (RV) dysfunction is a recognized driver of </span>adverse outcomes<span> in TR, the impact of myocardial tissue injury<span>, particularly nonischemic septal fibrosis (NIsF), remains largely unexplored.</span></span></div></div><div><h3>Objectives</h3><div>This study aims to evaluate the association of NIsF with adverse right-sided chamber remodeling and to assess its incremental prognostic value for mortality in patients with functional TR.</div></div><div><h3>Methods</h3><div>Patients with advanced (≥ moderate) functional TR underwent comprehensive cardiac magnetic resonance<span> (CMR) evaluation. Late gadolinium<span> enhancement (LGE) was used to identify NIsF, defined as hyperenhancement in the midmyocardial or epicardial regions of the interventricular septum. Cine CMR measured functional and geometric indices of the left and right sides of the heart. Follow-up data were obtained for all-cause mortality.</span></span></div></div><div><h3>Results</h3><div><span>A total of 663 patients with advanced TR (mean age: 63.8 ± 16.0 years; 53% male) were studied, and 29.4% were found to have NIsF. NIsF was strongly associated with adverse chamber remodeling, including larger left ventricular and RV volumes, reduced systolic function, and increased TR severity (all </span><em>P &lt;</em><span> 0.001). TR regurgitant fraction increased stepwise with NIsF extent (no NIsF, 34.9% ± 1.5%; 1 segment, 38.1% ± 13.0%; 2 segments, 40.8% ± 13.8%; </span><em>P &lt;</em> 0.001). Over a mean follow-up of 4.3 ± 4.3 years, 25.3% of patients died. NIsF was independently associated with mortality (HR: 1.79 [95% CI: 1.26-2.56]; <em>P =</em> 0.001), even after adjusting for conventional risk markers, including age, TR severity, RV dysfunction, and dilation. Kaplan-Meier analysis demonstrated significantly higher mortality risk among patients with NIsF compared with patients without NIsF (<em>P &lt;</em> 0.001).</div></div><div><h3>Conclusions</h3><div>Among patients with advanced TR, NIsF is an important marker of adverse right-sided chamber remodeling and provides incremental prognostic utility beyond conventional risk markers.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages 959-969"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144547998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiple Domains of Functional Imaging Provide Comprehensive Risk Characterization in Chronic Coronary Syndromes","authors":"Jamieson M. Bourque MD, MHS","doi":"10.1016/j.jcmg.2025.07.005","DOIUrl":"10.1016/j.jcmg.2025.07.005","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages 956-958"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What Can Atherosclerosis Imaging Teach Us About Healthy Vascular Aging?","authors":"Ron Blankstein MD ,&nbsp;Christina Magnussen MD ,&nbsp;Khurram Nasir MD, MPH, MSc","doi":"10.1016/j.jcmg.2025.07.014","DOIUrl":"10.1016/j.jcmg.2025.07.014","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages 994-996"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Last Decade in Tricuspid Regurgitation","authors":"Rebecca T. Hahn MD ,&nbsp;Luigi Badano MD, PhD ,&nbsp;Fabien Praz MD ,&nbsp;Denisa Muraru MD, PhD ,&nbsp;Eustachio Agricola MD ,&nbsp;Nina Ajmone Marsan MD, PhD ,&nbsp;Joanna Bartkowiak MD ,&nbsp;Victoria Delgado MD, PhD ,&nbsp;Julien Dreyfus MD, PhD ,&nbsp;Jörg Hausleiter MD ,&nbsp;Philipp Lurz MD ,&nbsp;Francesco Maisano MD ,&nbsp;Davide Margonato MD ,&nbsp;David Messika-Zeitoun MD, PhD ,&nbsp;Maurice Enriquez-Sarano MD ,&nbsp;João L. Cavalcante MD","doi":"10.1016/j.jcmg.2025.03.003","DOIUrl":"10.1016/j.jcmg.2025.03.003","url":null,"abstract":"<div><div>The tricuspid valve<span><span> has become a major focus of novel structural heart interventions, with the Conformité Européenne approval of 5 devices in Europe and the U.S. Food and Drug Administration approval of 2 devices in the United States. Multiple meta-analyses and large population-based registries have shown that although significant tricuspid regurgitation (TR) often accompanies left heart or </span>pulmonary vascular diseases<span>, it is associated with an increased risk of mortality and a reduced quality of life<span> after adjusting for these comorbidities. Echocardiography<span> remains the imaging modality of choice for diagnosing the etiology and assessing the severity of TR. However, advanced imaging techniques have played an essential role in the rapid advancement of the structural field and, in particular, transcatheter interventions for TR. Herein, we review the advances made in this field, focusing on the role that imaging has played in shaping a new field of study.</span></span></span></span></div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages 1013-1041"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution and Clinical Relevance of Left Atrial Appendage Residual Patency After Percutaneous Closure","authors":"Roberto Galea MD,&nbsp;Juan Perich Krsnik MD,&nbsp;Alan Arthur Peters MD,&nbsp;Federico de Marco MD,&nbsp;Adel Aminian MD,&nbsp;Nicolas Meneveau MD,&nbsp;Konstantina Chalkou PhD,&nbsp;Christoph Gräni MD, PhD,&nbsp;Frederic Anselme MD, PhD,&nbsp;Anna Franzone MD, PhD,&nbsp;Pascal Vranckx MD, PhD,&nbsp;Urs Fischer MD,&nbsp;Francesco Bedogni MD,&nbsp;Lorenz Räber MD, PhD,&nbsp;Marco Valgimigli MD, PhD","doi":"10.1016/j.jcmg.2025.05.004","DOIUrl":"10.1016/j.jcmg.2025.05.004","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages 1059-1061"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full Issue PDF","authors":"","doi":"10.1016/S1936-878X(25)00430-9","DOIUrl":"10.1016/S1936-878X(25)00430-9","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages II-CXXXIII"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144934022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocardial Late Gadolinium Enhancement","authors":"Raymond Y. Kwong MD, MPH (Associate Editor, JACC: Cardiovascular Imaging),&nbsp;Y.S. Chandrashekhar MD, DM (Editor-in-Chief, JACC: Cardiovascular Imaging)","doi":"10.1016/j.jcmg.2025.07.015","DOIUrl":"10.1016/j.jcmg.2025.07.015","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 9","pages":"Pages 1068-1070"},"PeriodicalIF":15.2,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}