JACC. Cardiovascular imaging最新文献

{"title":"Articulating the JACC Journals’ Direction in Times of Global Change","authors":"Harlan M. Krumholz MD, SM (Editor-in-Chief, JACC), Biykem Bozkurt MD, PhD (Editor-in-Chief, JACC: Heart Failure), Y. Chandrashekhar MD (Editor-in-Chief, JACC: Cardiovascular Imaging), Bonnie Ky MD, MSCE (Editor-in-Chief, JACC: CardioOncology), Douglas L. Mann MD (Editor-in-Chief, JACC: Basic to Translational Science), David J. Moliterno MD (Editor-in-Chief, JACC: Cardiovascular Interventions), Kalyanam Shivkumar MD, PhD (Editor-in-Chief, JACC: Clinical Electrophysiology), Candice K. Silversides MD (Editor-in-Chief, JACC: Advances), Gilbert H.L. Tang MD, MSc, MBA (Editor-in-Chief, JACC: Case Reports), Jian’an Wang MD, PhD (Editor-in-Chief, JACC: Asia)","doi":"10.1016/j.jcmg.2025.02.002","DOIUrl":"10.1016/j.jcmg.2025.02.002","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 4","pages":"Pages 522-523"},"PeriodicalIF":12.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Aortic Regurgitation","authors":"Akhil Narang MD, James D. Thomas MD, Robert O. Bonow MD","doi":"10.1016/j.jcmg.2025.01.012","DOIUrl":"10.1016/j.jcmg.2025.01.012","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 4","pages":"Pages 418-420"},"PeriodicalIF":12.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guideline-Directed Application of Coronary Artery Calcium Scores for Primary Prevention of Atherosclerotic Cardiovascular Disease","authors":"Jelena Pavlović MD, MSc ,&nbsp;Daniel Bos MD, PhD ,&nbsp;M. Kamran Ikram MD, PhD ,&nbsp;M. Arfan Ikram MD, PhD ,&nbsp;Maryam Kavousi MD, PhD ,&nbsp;Maarten J.G. Leening MD, PhD","doi":"10.1016/j.jcmg.2024.12.008","DOIUrl":"10.1016/j.jcmg.2024.12.008","url":null,"abstract":"<div><h3>Background</h3><div>The 2018 ACC (American College of Cardiology)/AHA (American Heart Association) and 2021 ESC (European Society of Cardiology)/EAS (European Atherosclerosis Society) guidelines recommend coronary artery calcium (CAC) score for risk refinement in primary prevention of atherosclerotic cardiovascular disease (ASCVD).</div></div><div><h3>Objectives</h3><div>This study sought to compare CAC utility as a risk-refining tool following the ACC/AHA guideline using pooled cohort equations (PCE) or PREVENT (Predicting Risk of cardiovascular disease EVENTs) equations and ESC/EAS guideline using SCORE2 (Systematic COronary Risk Evaluation 2).</div></div><div><h3>Methods</h3><div>A total of 1,903 statin-naive participants 55 to 75 years of age, free of ASCVD and diabetes, with low-density lipoprotein cholesterol &lt;190 mg/dL from the prospective population-based Rotterdam Study were included. Per the guidelines, we determined proportions of CAC scan–eligible and reclassified men and women, ASCVD incidence rates, and numbers needed to treat for 10 years (NNT_10y).</div></div><div><h3>Results</h3><div>By the ACC/AHA (PCE), 18.3% of men and 11.9% of women, and by ACC/AHA (PREVENT), 13.4% of men and 3.4% of women were eligible for a CAC scan. By the ESC/EAS, 46.6% of men and 44.9% of women were CAC eligible. Proportions of uprisked and derisked individuals varied per guideline. Among ACC/AHA and ESC/EAS CAC-eligible individuals, incidence rates ranged from 9.3 to 23.8 per 1,000 person-years, and the estimated NNT_10y to prevent 1 ASCVD event, based on high-intensity statin use, varied from 11 to 26.</div></div><div><h3>Conclusions</h3><div>The ACC/AHA and ESC/EAS guidelines differ in the selection and application of the CAC score for primary prevention of ASCVD. Guideline-directed application of CAC score in a middle-aged apparently healthy population improved risk stratification at an acceptable NNT_10y for both guidelines.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 4","pages":"Pages 465-475"},"PeriodicalIF":12.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Number Needed to Defeat?","authors":"Philip Greenland MD ,&nbsp;Kim A. Williams Sr. MD","doi":"10.1016/j.jcmg.2025.01.011","DOIUrl":"10.1016/j.jcmg.2025.01.011","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 4","pages":"Pages 476-477"},"PeriodicalIF":12.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ironing It Out","authors":"Kevin Kai Li MD, PhD ,&nbsp;Michael Salerno MD, PhD, MS","doi":"10.1016/j.jcmg.2024.10.008","DOIUrl":"10.1016/j.jcmg.2024.10.008","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 4","pages":"Pages 448-450"},"PeriodicalIF":12.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allocation of Semaglutide According to Coronary Artery Calcium and BMI","authors":"Alexander C. Razavi MD, MPH, PhD ,&nbsp;Alexander M. Cao Zhang MD ,&nbsp;Zeina A. Dardari MS ,&nbsp;Khurram Nasir MD, MPH, MSc ,&nbsp;Michael Khorsandi MD ,&nbsp;Martin Bødtker Mortensen MD, PhD ,&nbsp;Mouaz H. Al-Mallah MD, MSc ,&nbsp;Michael D. Shapiro DO, MCR ,&nbsp;Melissa A. Daubert MD ,&nbsp;Roger S. Blumenthal MD ,&nbsp;Laurence S. Sperling MD ,&nbsp;Seamus P. Whelton MD, MPH ,&nbsp;Michael J. Blaha MD, MPH ,&nbsp;Omar Dzaye MD, MPH, PhD","doi":"10.1016/j.jcmg.2024.10.004","DOIUrl":"10.1016/j.jcmg.2024.10.004","url":null,"abstract":"<div><h3>Background</h3><div>Implementation of semaglutide weight loss therapy has been challenging due to drug supply and cost, underscoring a need to identify those who derive the greatest absolute benefit.</div></div><div><h3>Objectives</h3><div>Allocation of semaglutide was modeled according to coronary artery calcium (CAC) among individuals without diabetes or established atherosclerotic cardiovascular disease (CVD).</div></div><div><h3>Methods</h3><div>In this analysis, 3,129 participants in the MESA (Multi-Ethnic Study of Atherosclerosis) without diabetes or clinical CVD met body mass index criteria for semaglutide and underwent CAC scoring on noncontrast cardiac computed tomography. Cox proportional hazards regression assessed the association of CAC with major adverse cardiovascular events (MACE), heart failure (HF), chronic kidney disease (CKD), and all-cause mortality. Risk reduction estimates from the SELECT (Semaglutide Effects on Heart Disease and Stroke in Patients with Overweight or Obesity) trial (median follow-up: 3.3 years) were applied to observed incidence rates for semaglutide 5-year number-needed-to-treat calculations.</div></div><div><h3>Results</h3><div>Mean age was 61.2 years, 54% were female, 62% were non-White, mean body mass index was 31.8 kg/m², and 49% had CAC. Compared with CAC = 0, CAC ≥300 conferred a 2.2-fold higher risk for MACE (HR: 2.16 [95% CI: 1.57-2.99]; <em>P &lt;</em> 0.001). Higher risks for HF (HR: 2.80 [95% CI: 1.81-4.35]; <em>P &lt;</em> 0.001), CKD (HR: 1.59 [95% CI: 1.15-2.22]; <em>P =</em> 0.006), and all-cause mortality (HR: 1.35 [95% CI: 1.08-1.69]; <em>P =</em> 0.009) comparing CAC ≥300 vs CAC = 0 were also observed. There were large 5-year number-needed-to-treat differences between CAC = 0 and CAC ≥300 for MACE (653 vs 79), HF (1,094 vs 144), CKD (1,044 vs 144), and all-cause mortality (408 vs 98).</div></div><div><h3>Conclusions</h3><div>Measurement of CAC may enhance value of care with weight loss dose semaglutide in those without diabetes or clinical CVD, improving allocation of a limited health care resource.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 4","pages":"Pages 451-461"},"PeriodicalIF":12.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142965076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full Issue PDF","authors":"","doi":"10.1016/S1936-878X(25)00122-6","DOIUrl":"10.1016/S1936-878X(25)00122-6","url":null,"abstract":"","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 4","pages":"Pages I-CXXVI"},"PeriodicalIF":12.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Evaluation of Chronic Aortic Regurgitation","authors":"Rowa Attar MD ,&nbsp;Maan Malahfji MD ,&nbsp;Clara Angulo RDCS ,&nbsp;Duc T. Nguyen MD, PhD ,&nbsp;Edward A. Graviss PhD, MPH ,&nbsp;Dipan J. Shah MD ,&nbsp;William A. Zoghbi MD, MACC","doi":"10.1016/j.jcmg.2024.08.013","DOIUrl":"10.1016/j.jcmg.2024.08.013","url":null,"abstract":"<div><h3>Background</h3><div>Guidelines for echocardiographic evaluation of aortic regurgitation (AR) have not been validated against an independent quantitative standard.</div></div><div><h3>Objectives</h3><div>The aim of this study was to evaluate the accuracy of the ASE (American Society of Echocardiography) AR guidelines against cardiac magnetic resonance (CMR) and to develop simplified approaches for detection of significant AR.</div></div><div><h3>Methods</h3><div>Patients with AR underwent echocardiography and CMR &lt;4 hours apart. AR severity was graded according to ASE guidelines. Quantitation of regurgitant volume (RegV) was performed with pulsed Doppler at the mitral annulus and right ventricular outflow compared with left ventricular (LV) outflow, and with proximal isovelocity surface area.</div></div><div><h3>Results</h3><div>The authors studied 81 patients; median age was 52 years, and 58% had a bicuspid aortic valve. According to echo, 35 (43%) patients had mild AR, 18 (22%) moderate, 12 (15%) moderate to severe, and 16 (20%) had severe AR. The area under the curve (AUC) for detection of severe AR by CMR using ASE grading was 0.9 (82.4% sensitivity and 96.9% specificity). Feasibility of RegV quantitation was &gt;88% using either echo volumetric method, and it was low for proximal isovelocity surface area (37%). The highest accuracy for echo parameters against CMR was seen with vena contracta width, jet width, and LV end-diastolic volume index (AUC: 0.86-0.89); pressure half-time had the lowest accuracy. Without RegV quantitation, a vena contracta width ≥0.5 cm and indexed LV end-diastolic volume ≥82 mL/m² had 95.5% positive predictive value and 87.5% negative predictive value for identifying ≥moderate to severe AR by CMR (AUC: 0.89).</div></div><div><h3>Conclusions</h3><div>The ASE guidelines display very good performance in identifying significant AR. A simplified approach using vena contracta width and LV volumes can be used to reliably identify significant AR. Further validation of the findings in larger cohorts and against clinical outcomes is needed.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 4","pages":"Pages 403-417"},"PeriodicalIF":12.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Racial and Ethnic Differences in Long-Term Cardiovascular Mortality Among Women and Men From the CAC Consortium.","authors":"Shmuel Rosenblatt, Michael J Blaha, Ron Blankstein, Khurram Nasir, Fay Lin, Yvette Yeboah-Kordieh, Daniel S Berman, Michael D Miedema, Seamus P Whelton, John Rumberger, Matthew J Budoff, Jonathon Leipsic, Leslee J Shaw","doi":"10.1016/j.jcmg.2025.01.013","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.01.013","url":null,"abstract":"<p><strong>Background: </strong>Despite an increasingly diverse population, knowledge regarding racial and ethnic disparities is limited among women and men undergoing atherosclerotic cardiovascular (ASCVD) risk assessment.</p><p><strong>Objectives: </strong>The aim of this study was to compare cardiovascular (CV) mortality by ASCVD risk and coronary artery calcium (CAC) scores among Black and Hispanic women and men compared with other participants.</p><p><strong>Methods: </strong>From the CAC Consortium, 42,964 participants with self-reported race and ethnicity were followed for a median of 11.7 years. Multivariable Cox proportional hazards regression models were used to estimate CV mortality, with separate analyses by sex.</p><p><strong>Results: </strong>One-third of enrollees were women; 977 self-reported as Black, 1,349 as Hispanic, 1,621 as Asian, and 740 as American Indian/Native Alaskan/Hawaiian or unspecified; the remainder were White. Black women and men had higher ASCVD risk and CAC scores yielding the highest CV mortality compared with other participants. Among Black women and men with a 0 CAC or ASCVD risk score <5%, HRs were 6- to 9-fold higher than that of other women and men. In men with CAC scores ≥100, Black men (HR: 4.2; P < 0.001) had the highest CV mortality compared to all other men. A similar high-risk pattern was noted for Black women with CAC scores ≥100 (P < 0.001), even with adjustment for the ASCVD risk score. Overall, Hispanics had an intermediate CV mortality, less than that of Black participants. This was notable for Hispanic men with a CAC score of 0 (HR: 3.6; P = 0.006) and CAC ≥100 (HR: 2.3; P = 0.03).</p><p><strong>Conclusions: </strong>The disproportionately high and excess CV mortality among Black women and men represents significant barriers to reducing the burden of ASCVD through effective risk assessment using ASCVD risk and CAC scores.</p>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Last Decade in Tricuspid Regurgitation: How Imaging Shaped a Field.","authors":"Rebecca T Hahn, Luigi Badano, Fabien Praz, Denisa Muraru, Eustachio Agricola, Nina Ajmone Marsan, Joanna Bartkowiak, Victoria Delgado, Julien Dreyfus, Jörg Hausleiter, Philipp Lurz, Francesco Maisano, Davide Margonato, David Messika-Zeitoun, Maurice Enriquez-Sarano, João L Cavalcante","doi":"10.1016/j.jcmg.2025.03.003","DOIUrl":"https://doi.org/10.1016/j.jcmg.2025.03.003","url":null,"abstract":"<p><p>The tricuspid valve has become a major focus of novel structural heart interventions, with the Conformité Européenne approval of 5 devices in Europe and the U.S. Food and Drug Administration approval of 2 devices in the United States. Multiple meta-analyses and large population-based registries have shown that although significant tricuspid regurgitation (TR) often accompanies left heart or pulmonary vascular diseases, it is associated with an increased risk of mortality and a reduced quality of life after adjusting for these comorbidities. Echocardiography remains the imaging modality of choice for diagnosing the etiology and assessing the severity of TR. However, advanced imaging techniques have played an essential role in the rapid advancement of the structural field and, in particular, transcatheter interventions for TR. Herein, we review the advances made in this field, focusing on the role that imaging has played in shaping a new field of study.</p>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":12.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}