JACC. Heart failure最新文献

{"title":"Full issue PDF","authors":"","doi":"10.1016/S2213-1779(25)00259-8","DOIUrl":"10.1016/S2213-1779(25)00259-8","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages i-ccxviii"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Future of Artificial Intelligence–Assisted Event Adjudication","authors":"Jonathan W. Cunningham MD, MPH , Christopher M. O’Connor MD","doi":"10.1016/j.jchf.2025.03.015","DOIUrl":"10.1016/j.jchf.2025.03.015","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages 722-724"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143908306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond Coronary Atherosclerosis","authors":"Romit Bhattacharya MD , Khurram Nasir MD","doi":"10.1016/j.jchf.2025.02.009","DOIUrl":"10.1016/j.jchf.2025.02.009","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages 752-753"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization and Outcomes of Ex Vivo Heart Perfusion in Donation After Brain Death Heart Transplantation","authors":"Joseph B. Lerman MD , Veraprapas Kittipibul MD , Cynthia L. Green PhD , Karen Flores Rosario MD , Chetan B. Patel MD , Richa Agarwal MD , Jeffrey E. Keenan MD , Carmelo A. Milano MD , Jacob N. Schroder MD , Adam D. DeVore MD, MHS","doi":"10.1016/j.jchf.2025.01.027","DOIUrl":"10.1016/j.jchf.2025.01.027","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages 860-862"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143908321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Uptitration of Recommended Heart Failure Medications on Restricted Mean Survival Time in STRONG-HF","authors":"Ashok Krishnaswami MD, MAS , Beth A. Davison PhD , Christopher Edwards BS , Gad Cotter MD , Marco Metra MD , Ovidiu Chioncel MD, PhD , Karen Sliwa MD, PhD , Adriaan A. Voors MD, PhD , Alexandre Mebazaa MD, PhD , Deepak L. Bhatt MD, MPH, MBA","doi":"10.1016/j.jchf.2025.02.020","DOIUrl":"10.1016/j.jchf.2025.02.020","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages 873-876"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beta-Blockers and Long-Term Mortality in Takotsubo Syndrome","authors":"Sergio Raposeiras-Roubin MD, PhD ,&nbsp;Francesco Santoro MD, PhD ,&nbsp;Luca Arcari MD ,&nbsp;Ravi Vazirani MD ,&nbsp;Giuseppina Novo MD ,&nbsp;Aitor Uribarri MD ,&nbsp;Mariano Enrica MD ,&nbsp;Javier Lopez-Pais MD ,&nbsp;Federico Guerra MD ,&nbsp;Fernando Alfonso MD, PhD ,&nbsp;Toni Pätz MD ,&nbsp;Clara Fernandez-Cordon MD ,&nbsp;Roberta Montisci MD ,&nbsp;Miguel Corbi-Pascual MD ,&nbsp;Maria Francesca Marchetti MD ,&nbsp;Manuel Almendro MD ,&nbsp;Luca Cacciotti MD ,&nbsp;Oscar Vedia MD ,&nbsp;Ibrahim El-Battrawy MD ,&nbsp;Emilia Blanco-Ponce MD ,&nbsp;Ivan J. Nuñez-Gil MD, PhD","doi":"10.1016/j.jchf.2024.11.015","DOIUrl":"10.1016/j.jchf.2024.11.015","url":null,"abstract":"<div><h3>Background</h3><div>Beta-blockers are considered a reasonable therapy for patients with Takotsubo syndrome (TTS), commonly used despite the absence of consistent evidence about its prognosis impact.</div></div><div><h3>Objectives</h3><div>This study aimed to assess the impact of beta-blocker therapy on long-term mortality and TTS recurrence.</div></div><div><h3>Methods</h3><div>The authors analyzed 2,853 patients discharged with a confirmed TTS diagnosis, enrolled in the international multicenter GEIST (The GErman Italian Spanish Takotsubo Registry). They performed a propensity score matching analysis to draw up 2 groups of 697 patients paired according to whether or not they received medical therapy with beta-blockers at hospital discharge. The prognostic value of beta-blockers at discharge to predict mortality and TTS recurrence during follow-up was analyzed using Cox regression.</div></div><div><h3>Results</h3><div>During a mean follow-up of 2.6 years, 485 patients (17.0%) died and 97 (3.4%) have had TTS recurrence. Patients treated with beta-blockers at discharge (n = 2,125) (74.5%) had a lower mortality rate (6.0 vs 8.1 per 100 patients/year). After propensity score matching, the authors found that mortality during follow-up was lower in the beta-blocker group (HR: 0.71; 95% CI: 0.55-0.90). Differences in mortality were especially at the expense of mortality in the first year. No differences were found by subgroups. Moreover, beta-blocker therapy was not associated with lower TTS recurrence during the follow-up (HR: 0.74; 95% CI: 0.61-1.89). No association between the use of beta-blockers at discharge and left ventricle ejection fraction recovery has also been observed.</div></div><div><h3>Conclusions</h3><div>Beta-blocker therapy in patients with TTS is associated with lower follow-up mortality, but not with lower TTS recurrence. (The GErman Italian Spanish Takotsubo Registry [GEIST]; <span><span>NCT04361994</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages 815-825"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Days Alive Out of Hospital for Patients with Left Ventricular Dysfunction","authors":"Kamil F. Faridi MD, MSc ,&nbsp;Haocheng Huang MS ,&nbsp;Helen Parise ScD ,&nbsp;Tariq Ahmad MD, MPH ,&nbsp;Makoto Mori MD, PhD ,&nbsp;Mabel Chung MD, MPH ,&nbsp;Robert W. Yeh MD, MSc, MBA ,&nbsp;Mark C. Petrie MD ,&nbsp;Julio A. Panza MD ,&nbsp;Jean L. Rouleau MD ,&nbsp;Rafal Dabrowski MD, PhD ,&nbsp;Eric J. Velazquez MD","doi":"10.1016/j.jchf.2025.02.019","DOIUrl":"10.1016/j.jchf.2025.02.019","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages 867-869"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elevated Neutrophil-to-Lymphocyte Ratio Predicts Prognosis in Acute Myocarditis","authors":"Antonio Cannata MD, PhD ,&nbsp;Amitai Segev MD ,&nbsp;Cristina Madaudo MD ,&nbsp;Emanuele Bobbio MD, PhD ,&nbsp;Chiara Baggio MD ,&nbsp;Jonathan Schütze MD ,&nbsp;Piero Gentile MD ,&nbsp;Marta Sanguineti MD ,&nbsp;Luca Monzo MD, PhD ,&nbsp;Matteo Schettino MD ,&nbsp;Emma Ferone MBBS ,&nbsp;Ahmed Elsanhoury MD ,&nbsp;Anan Younis MD ,&nbsp;Matteo Palazzini MD ,&nbsp;Adriana Ferroni ,&nbsp;Valentina Giani MD ,&nbsp;Matthew Sadler MD ,&nbsp;Daniela Di Lisi MD, PhD ,&nbsp;Mohammad Albarjas MD ,&nbsp;Leonardo Calò MD ,&nbsp;Daniel I. Bromage MD, PhD","doi":"10.1016/j.jchf.2024.11.003","DOIUrl":"10.1016/j.jchf.2024.11.003","url":null,"abstract":"<div><h3>Background</h3><div>Neutrophil-to-lymphocyte ratio (NLR) is an easy-to-use inflammatory biomarker. Baseline NLR is independently associated with incident cardiovascular events and all-cause mortality. However, whether this applies to acute myocarditis (AM) has not been evaluated.</div></div><div><h3>Objectives</h3><div>The present study aimed to investigate the prognostic value of NLR in patients with AM.</div></div><div><h3>Methods</h3><div>A total of 1,150 consecutive patients with a diagnosis of AM admitted to 10 international tertiary referral cardiac centers were included in the study. The diagnosis was confirmed using cardiac magnetic resonance or endomyocardial biopsy. The primary outcome measure was a composite of all-cause mortality or heart transplantation. Patients were divided into 2 groups according to an NLR cutoff of 4 derived from spline regression analysis and 70:30 train-test split algorithm.</div></div><div><h3>Results</h3><div>Patients with an NLR &lt;4 were younger and more likely to present with chest pain, and those with an NLR ≥4 were more likely to present with breathlessness and have other comorbidities. Over a median follow-up of 228 weeks, a NLR ≥4 was associated with a worse prognosis (<em>P &lt;</em> 0.0001). After adjustment for prognostic variables, NLR emerged as an independent predictor of outcome (HR: 3.03 [95% CI: 1.30-7.04]; <em>P =</em> 0.010). Elevated NLR remained associated with worse outcomes among patients with preserved ejection fraction at baseline, who are conventionally considered to be at lower risk of adverse events (<em>P &lt;</em> 0.0001).</div></div><div><h3>Conclusions</h3><div>In patients with AM, elevated NLR is associated with worse prognosis and may be valuable for stratifying patients, even those conventionally considered at low risk.</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages 770-780"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Inextricable Link Between Atrial Fibrillation and Heart Failure With Preserved Ejection Fraction","authors":"Jeanne E. Poole MD,&nbsp;April Stempien-Otero MD","doi":"10.1016/j.jchf.2025.03.012","DOIUrl":"10.1016/j.jchf.2025.03.012","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages 795-797"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Critical Appraisal of Beta-Blocker Therapy in Takotsubo Syndrome","authors":"Anique Ducharme MD, MSc","doi":"10.1016/j.jchf.2025.02.012","DOIUrl":"10.1016/j.jchf.2025.02.012","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 5","pages":"Pages 826-828"},"PeriodicalIF":10.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143907530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}