JACC. Heart failure最新文献

{"title":"SGLT2 Inhibitors and Serious Renal Events Among Patients With Heart Failure With Reduced Ejection Fraction","authors":"Henrik Svanström PhD , George Frederick Mkoma MD, PhD , Anders Hviid DMSC , Björn Pasternak MD, PhD","doi":"10.1016/j.jchf.2025.102522","DOIUrl":"10.1016/j.jchf.2025.102522","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102522"},"PeriodicalIF":10.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stop Treating the Numbers","authors":"Jacob C. Jentzer MD, MS , Aniket S. Rali MD , P. Elliott Miller MD, MHS","doi":"10.1016/j.jchf.2025.102560","DOIUrl":"10.1016/j.jchf.2025.102560","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102560"},"PeriodicalIF":10.3,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Artery Disease Is Still a Major Cause of Heart Failure","authors":"Peter P. Swoboda PhD , Mark C. Petrie MD","doi":"10.1016/j.jchf.2025.102569","DOIUrl":"10.1016/j.jchf.2025.102569","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102569"},"PeriodicalIF":10.3,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidisciplinary Screening of a Novel Founder LMNA Mutation Associated With Cardiomyopathy in a Geographic Isolate","authors":"Giovanni Peretto MD, PhD , Andrea Villatore MD , Luca Bosco MD , Paolo Porro BS , Camilla M.M. Strano MD , Benedetta Sorrenti MD , Angelomaria Sista , Pasquale Ceres MS , Chiara Mocetti BS , Alessia Cecere BS , Gelsomina Cione MD , Paola Carrera PhD , Antonio Esposito MD , Paolo Della Bella MD , Stefano C. Previtali MD, PhD , Chiara Di Resta PhD , Simone Sala MD","doi":"10.1016/j.jchf.2025.102567","DOIUrl":"10.1016/j.jchf.2025.102567","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102567"},"PeriodicalIF":10.3,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144623687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Magnetic Resonance Imaging vs Coronary Angiography as Primary Strategy in Newly Diagnosed Heart Failure","authors":"Gülmisal Güder MD, PhD ,&nbsp;Theresa Reiter MD ,&nbsp;Wolfgang R. Bauer MD, PhD ,&nbsp;Theano Papavassiliu MD ,&nbsp;Johannes Schwab MD ,&nbsp;Matthias Pauschinger MD ,&nbsp;Daniel Lavall MD ,&nbsp;Rolf Wachter MD ,&nbsp;Dominik Berliner MD ,&nbsp;Johann Bauersachs MD ,&nbsp;Stefan Frantz MD ,&nbsp;Götz Gelbrich PhD, PhD ,&nbsp;Georg Ertl MD ,&nbsp;Stefan Störk MD, PhD","doi":"10.1016/j.jchf.2025.102528","DOIUrl":"10.1016/j.jchf.2025.102528","url":null,"abstract":"<div><h3>Background</h3><div>New-onset heart failure with reduced ejection fraction (HFrEF) requires further diagnostic evaluation to determine its underlying cause. Despite the potential of cardiac magnetic resonance (CMR) imaging to identify ischemic and nonischemic causes, percutaneous invasive coronary angiography (CATH) remains the preferred tool for diagnosing ischemic cardiomyopathy (ICM).</div></div><div><h3>Objectives</h3><div>This study aimed to determine whether a CMR-first strategy could diagnose ICM as effectively as CATH (primary endpoint) and potentially reduce the number of invasive procedures (secondary endpoint).</div></div><div><h3>Methods</h3><div>In this multicenter 2-armed diagnostic trial (Magnetic Resonance Imaging vs Invasive Coronary Angiography as First-Line Diagnostic Modality in New-Onset Heart Failure), 229 adults with new-onset HFrEF were randomized to undergo CMR or CATH first and the other modality second. Separate expert panels evaluated both modalities, blinded to each other’s results. The cardiologist-in-charge was blinded to the panel results and served as the reference standard.</div></div><div><h3>Results</h3><div>A total of 203 patients (mean age: 62 ± 14 years, 28% women) had evaluable pairs of diagnostic modalities (108 CATH-first). For diagnosing ICM, the panels considered CATH to be sufficient in 100% (105/105) and CMR in 80% (76/95; <em>P &lt;</em> 0.001). Compared with the reference, sensitivity for diagnosing ICM was high for both (CATH 91%, CMR 90%; <em>P =</em> 1.00), but CMR had lower specificity (98% vs 74%; <em>P &lt;</em> 0.001). According to the CMR panel, 48% (46/95) of CATH procedures could have been avoided with a CMR-first strategy, dropping to 45% when excluding patients who underwent coronary interventions.</div></div><div><h3>Conclusions</h3><div>Although CATH was superior for diagnosing ICM, CMR showed similar sensitivity and could significantly reduce CATH procedures without increasing the risk of missing critical coronary interventions. Longitudinal studies are needed to assess whether a CMR-first strategy confers prognostic benefit. (Magnetic Resonance Imaging vs Invasive Coronary Angiography as First-Line Diagnostic Modality in New-Onset Heart Failure; <span><span>ISRCTN16515058</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102528"},"PeriodicalIF":10.3,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144611813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographic Variation and Human Development Index in Heart Failure With Reduced Ejection Fraction","authors":"Alain Cohen-Solal MD, PhD ,&nbsp;Wendimagegn Alemayehu PhD ,&nbsp;Carolyn S.P. Lam MBBS, PhD ,&nbsp;Hiroyuki Tsutsui MD, PhD ,&nbsp;Jian Zhang MD, PhD ,&nbsp;Armando Godoy-Palomino MD ,&nbsp;Dimitrios N. Tziakas MD, PhD ,&nbsp;Stefano Corda MD, PhD ,&nbsp;Ciaran J. McMullan MMSc, MBBCh BAO (Hon), MSc, BA (Hons) ,&nbsp;Justin A. Ezekowitz MBBCh, MSc ,&nbsp;Adrian F. Hernandez MD, MHS ,&nbsp;Burkert Pieske MD ,&nbsp;Christopher M. O’Connor MD ,&nbsp;Cynthia M. Westerhout PhD ,&nbsp;Paul W. Armstrong MD ,&nbsp;VICTORIA Study Group","doi":"10.1016/j.jchf.2025.102548","DOIUrl":"10.1016/j.jchf.2025.102548","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102548"},"PeriodicalIF":10.3,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remote Monitoring in Heart Failure","authors":"Ioannis Skalidis MD, PhD ,&nbsp;Niccolo Maurizi MD ,&nbsp;Georgios Tzimas MD ,&nbsp;Henri Lu MD ,&nbsp;Panagiotis Antiochos MD","doi":"10.1016/j.jchf.2025.102544","DOIUrl":"10.1016/j.jchf.2025.102544","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102544"},"PeriodicalIF":10.3,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatiotemporal Clustering of Premature Heart Failure Mortality Across U.S. Counties, 2000-2023","authors":"Akshaya Srikanth Bhagavathula PhD","doi":"10.1016/j.jchf.2025.102559","DOIUrl":"10.1016/j.jchf.2025.102559","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102559"},"PeriodicalIF":10.3,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Call to Action","authors":"Bridget O’Connell PharmD ,&nbsp;Anju Sahay PhD ,&nbsp;Aradhana Verma MD ,&nbsp;Hayden B. Bosworth PhD ,&nbsp;Tomasz Jurga PharmD ,&nbsp;Orly Vardeny PharmD, MS ,&nbsp;Paul L. Hess MD, MHS ,&nbsp;Dave L. Dixon PharmD ,&nbsp;Benjamin W. Van Tassell PharmD ,&nbsp;Paul A. Heidenreich MD, MS ,&nbsp;Alexander T. Sandhu MD, MS","doi":"10.1016/j.jchf.2025.102552","DOIUrl":"10.1016/j.jchf.2025.102552","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102552"},"PeriodicalIF":10.3,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disentangling Convergent and Divergent Pathways to HFpEF and HFrEF","authors":"Neela D. Thangada MD,&nbsp;Sadiya S. Khan MD,&nbsp;Matthew J. Feinstein MD, MSc","doi":"10.1016/j.jchf.2025.102557","DOIUrl":"10.1016/j.jchf.2025.102557","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 9","pages":"Article 102557"},"PeriodicalIF":10.3,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}