左心室辅助装置中的三尖瓣反流

IF 10.3 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Boaz Elad MD , Emily Tat MD , Gabriel Sayer MD , Koji Takeda MD , Michael I. Brener MD , Dor Lotan MD , Daniel Burkhoff MD, PhD , Susheel Kodali MD , Rebecca Hahn MD , Martin B. Leon MD , Nir Uriel MD, MSc
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引用次数: 0

摘要

心力衰竭患者出现三尖瓣反流(TR)与不良预后相关。同样,持久左心室辅助装置(LVAD)支持患者的TR与发病率和死亡率增加有关。三尖瓣(TV)干预在LVAD植入时纠正TR的作用仍然不确定,因为迄今为止的多项研究在临床结果上显示了相互矛盾的结果。本文就LVAD受者TR的发生机制、LVAD植入术后TR的血流动力学影响以及矫正和未矫正TR在LVAD支持下的意义进行综述。它还检查了LVAD植入后TR的预测因素,并强调了现有已发表报告中的差异和差距。最后,本综述评估了新型经导管三尖瓣治疗在这些患者中的潜在作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tricuspid Regurgitation in Left Ventricular Assist Device
The presence of tricuspid regurgitation (TR) in patients with heart failure is associated with poor outcomes. Similarly, TR in patients with durable left ventricular assist device (LVAD) support is associated with increased morbidity and mortality. The role of tricuspid valve (TV) intervention to correct TR at the time of LVAD implantation remains uncertain because multiple studies thus far have shown conflicting results on clinical outcomes. This review discusses the mechanism of TR in LVAD recipients, the hemodynamic effects of TR after LVAD implantation, and the significance of corrected and uncorrected TR in the context of LVAD support. It also examines predictors of TR following LVAD implantation and highlights the discrepancies and gaps in the existing published reports. Finally, the review evaluates the potential role of novel transcatheter tricuspid therapies in these patients.
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来源期刊
JACC. Heart failure
JACC. Heart failure CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
21.20
自引率
2.30%
发文量
164
期刊介绍: JACC: Heart Failure publishes crucial findings on the pathophysiology, diagnosis, treatment, and care of heart failure patients. The goal is to enhance understanding through timely scientific communication on disease, clinical trials, outcomes, and therapeutic advances. The Journal fosters interdisciplinary connections with neuroscience, pulmonary medicine, nephrology, electrophysiology, and surgery related to heart failure. It also covers articles on pharmacogenetics, biomarkers, and metabolomics.
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