JACC. Heart failure最新文献

{"title":"Leveraging Global Data to Illuminate Pediatric Heart Failure","authors":"Yuan Lu ScD","doi":"10.1016/j.jchf.2025.04.011","DOIUrl":"10.1016/j.jchf.2025.04.011","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102500"},"PeriodicalIF":10.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Medical Therapy Using Remote Monitoring and Artificial Intelligence in Patients With Heart Failure","authors":"Raj M. Khandwalla MD, MA , Alex Shvartser MS , Raymond J. Zimmer MD , Merije Chukumerije MD , Michael Share MD , Ronit Zadikany MD , Michael Farkouh MD , Gregg Fonarow MD , Yaron Elad MD , Michelle Maya Kittleson MD, PhD","doi":"10.1016/j.jchf.2025.03.045","DOIUrl":"10.1016/j.jchf.2025.03.045","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102504"},"PeriodicalIF":10.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144313841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Neprilysin Inhibition on Plasma Proteins in Heart Failure With Mildly Reduced or Preserved Ejection Fraction","authors":"Luqing Zhang PhD , Brian L. Claggett PhD , Pablo M. Marti-Castellote PhD , Denise Yates PhD , Michael M. Mendelson MD, MSc , John J.V. McMurray MD , Michael R. Zile MD , William Chutkow MD, PhD , Scott D. Solomon MD , Jonathan W. Cunningham MD, MPH","doi":"10.1016/j.jchf.2025.04.012","DOIUrl":"10.1016/j.jchf.2025.04.012","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102502"},"PeriodicalIF":10.3,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144306215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Urinary Metal Levels and Incident Heart Failure","authors":"Irene Martinez-Morata MD, PhD ,&nbsp;Arce Domingo-Relloso PhD ,&nbsp;Melanie Mayer PhD ,&nbsp;Kathrin Schilling PhD ,&nbsp;Ronald A. Glabonjat PhD ,&nbsp;Katlyn McGraw PhD ,&nbsp;Tiffany R. Sanchez PhD ,&nbsp;Joel D. Kaufman MD, PhD ,&nbsp;Dhananjay Vaidya PhD ,&nbsp;Wendy Post MD, PhD ,&nbsp;Miranda Jones PhD ,&nbsp;Daichi Shimbo MD, PhD ,&nbsp;Ying Zhang PhD ,&nbsp;Amanda M. Fretts PhD ,&nbsp;Gernot Pichler MD, PhD ,&nbsp;Jason G. Umans MD, PhD ,&nbsp;Jose Manuel Garcia Pinilla MD, PhD ,&nbsp;Shelley A. Cole PhD ,&nbsp;Juan C. Martin-Escudero MD, PhD ,&nbsp;Josep Redon MD, PhD ,&nbsp;Ana Navas-Acien MD, PhD","doi":"10.1016/j.jchf.2025.03.046","DOIUrl":"10.1016/j.jchf.2025.03.046","url":null,"abstract":"<div><h3>Background</h3><div>Environmental metals are recognized cardiovascular disease risk factors, yet the role of metal exposure in heart failure (HF) risk remains understudied.</div></div><div><h3>Objectives</h3><div>This study aims to evaluate the prospective association of urinary metals with incident HF across 3 geographically and ethnically/racially diverse cohorts: MESA (Multi-Ethnic Study of Atherosclerosis) and SHS (Strong Heart Study) in the United States, and the Hortega Study in Spain.</div></div><div><h3>Methods</h3><div>Adults 18-85 years of age in MESA (n = 6,601), SHS (n = 2,917), and Hortega (n = 1,300) were followed up to 20 years. Urinary levels of a multi-metal panel were measured at baseline and corrected for urine dilution. Cox proportional hazards and Cox elastic-net models were used to estimate the multi-adjusted (sociodemographic/clinical/lifestyle covariates) HR of incident HF by individual metals and the mixture of 5 metals available in all cohorts, respectively. The pooled HR (95% CI) of HF by 1-unit increase in log2-transformed levels of individual metals (ie, doubling of the dose) across cohorts was estimated using a fixed effects meta-analysis. Analyses by left ventricular ejection fraction were conducted in a subset.</div></div><div><h3>Results</h3><div>A total of 1,001 participants developed HF. In adjusted models, significant associations (pooled HRs [95% CI] per doubling of urinary metal) were identified for cadmium (HR: 1.15 [95% CI: 1.07-1.24]) molybdenum (HR: 1.13 [95% CI: 1.05-1.22]), and zinc (HR: 1.22 [95% CI: 1.14-1.32]). The HRs (95% CIs) for the association of 1 IQR increase in the multi-metal mixture levels and incident HF were 1.38 (95% CI: 1.00-1.86) in MESA, HR: 1.55 (95% CI: 1.28-1.97) in SHS, and HR: 1.08 (95% CI: 0.85-1.63) in Hortega in fully adjusted models. Stratified models by left ventricular ejection fraction were consistent with the pooled results.</div></div><div><h3>Conclusions</h3><div>Urinary metals are risk factors of HF across 3 diverse populations, supporting the role of reducing metal exposures to lower HF risk.</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102510"},"PeriodicalIF":10.3,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144306574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low Education Levels Linked to Increased Mortality Following Acute Heart Failure Hospitalization in Brazil","authors":"Gustavo S. Pereira da Cunha MD ,&nbsp;Leonardo Henrique S. Melo MD ,&nbsp;Eduardo L. Adam MD, PhD ,&nbsp;Raphael Henrique D. Cirino MD, PhD ,&nbsp;Louise Morgan MSN ,&nbsp;Sidney C. Smith Jr. MD ,&nbsp;Odilson M. Silvestre MD, PhD ,&nbsp;Wilson Nadruz MD, PhD ,&nbsp;Fabio P. Taniguchi MD, PhD ,&nbsp;Miguel M. Fernandes-Silva MD, MPH, PhD","doi":"10.1016/j.jchf.2025.04.013","DOIUrl":"10.1016/j.jchf.2025.04.013","url":null,"abstract":"","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102506"},"PeriodicalIF":10.3,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144306575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Evidence on Tricuspid Regurgitation Interventions in Heart Failure","authors":"Rebecca T. Hahn MD ,&nbsp;Marianna Adamo MD ,&nbsp;Neil P. Fam MD, MSc","doi":"10.1016/j.jchf.2025.04.008","DOIUrl":"10.1016/j.jchf.2025.04.008","url":null,"abstract":"<div><div>Moderate or severe tricuspid regurgitation (TR) is seen in up to a quarter of patients with chronic heart failure (HF) and exceeds 50% in those with advanced HF symptoms. In patients with HF, the increasing severity of TR is associated with progressively worse survival. Data supporting the medical management of HF and TR continue to evolve with a greater appreciation of the pathophysiologic relationship between these diseases. The results of isolated tricuspid valve surgery vary based on the timing of the intervention and coexisting comorbidities. However, earlier intervention with timing optimized by the use of risk scores may improve these outcomes. Transcatheter tricuspid valve interventions have become a viable therapeutic option, particularly for high surgical risk patients, with a repair and replacement device currently commercially available, but they have yet to show mortality or HF hospitalization benefit. The timing and type of intervention as well as the expected clinical benefit of device therapy require further study.</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102493"},"PeriodicalIF":10.3,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144291051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Superior Waitlist Outcomes Among Patients Listed for Donation After Circulatory Death Heart Transplantation","authors":"Max Shin MD ,&nbsp;Omar Toubat MD, PhD ,&nbsp;Michael A. Catalano MD ,&nbsp;Amit Iyengar MD, MSE ,&nbsp;Mark R. Helmers MD ,&nbsp;Michaela Asher BS ,&nbsp;David Rekhtman BS ,&nbsp;Cindy Song BA ,&nbsp;Mauer Biscotti MD ,&nbsp;Marisa Cevasco MD, MPH","doi":"10.1016/j.jchf.2025.03.039","DOIUrl":"10.1016/j.jchf.2025.03.039","url":null,"abstract":"<div><h3>Background</h3><div>Recent advances in heart procurement techniques have facilitated the utilization of hearts obtained after circulatory death. However, discerning the population that stands to benefit most requires an understanding of waitlist outcomes.</div></div><div><h3>Objectives</h3><div>The objective of this study was to evaluate waitlist and post-transplant outcomes among patients listed for donation after circulatory death (DCD) hearts in the United States, stratified by listing status.</div></div><div><h3>Methods</h3><div>The UNOS (United Network for Organ Sharing) database was queried for all adult patients waitlisted for isolated heart transplantation between October 2018 and June 2024. Patients were stratified by approval for donation after brain death vs DCD hearts. DCD patients were subdivided into those who were DCD candidates at time of listing or later during their waitlist period. Waitlist and post-transplant outcomes were compared using Fine &amp; Gray and Kaplan-Meier analyses.</div></div><div><h3>Results</h3><div>A total of 24,970 patients were identified; of these, 8,191 (33%) were listed as DCD candidates. DCD status 2, 3, 4, and 6 patients were more likely to be transplanted and less likely to die on the waitlist. There were no differences in post-transplant survival in any group. Receipt of a DCD heart was not predictive of mortality. Patients initially listed as DCD candidates were significantly more likely to be transplanted than those who became DCD candidates later during their waitlist course.</div></div><div><h3>Conclusions</h3><div>With exception of status 1, patients waitlisted for DCD hearts experience shorter waitlist duration, improved rates of transplantation, and comparable long-term survival with donation after brain death recipients.</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102495"},"PeriodicalIF":10.3,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144291050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Etiology of Heart Failure Across the Ejection Fraction Spectrum and Association With Prognosis","authors":"Kristian Kozman MD ,&nbsp;Giulia Ferrannini MD, PhD ,&nbsp;Lina Benson MSc ,&nbsp;Ulf Dahlström MD, PhD ,&nbsp;Camilla Hage RN, PhD ,&nbsp;Gianluigi Savarese MD, PhD ,&nbsp;Bahira Shahim MD, PhD ,&nbsp;Lars H. Lund MD, PhD","doi":"10.1016/j.jchf.2025.03.037","DOIUrl":"10.1016/j.jchf.2025.03.037","url":null,"abstract":"<div><h3>Background</h3><div>The associations between heart failure (HF) etiology and ejection fraction (EF) category and the association between etiology and outcomes in different EF categories are poorly studied.</div></div><div><h3>Objectives</h3><div>The aim of this study was to assess differences in etiology and their impact on outcomes in patients with heart failure with reduced ejection fraction (HFrEF), heart failure with mildly reduced ejection fraction (HFmrEF), and heart failure with preserved ejection fraction (HFpEF).</div></div><div><h3>Methods</h3><div>Patients enrolled in SwedeHF (Swedish Heart Failure Registry) between April 2010 and December 2023 were included. Patients were categorized according to HF etiology (ischemic, valvular, hypertensive, dilated cardiomyopathy, alcoholic cardiomyopathy, and other) and EF category. The primary outcome was the composite of time to all-cause death and first HF hospitalization. Logistic multinominal regression was used to assess the association between HF etiology and EF category, and Cox regression was used to assess the association between etiology and outcome within each EF category.</div></div><div><h3>Results</h3><div>Among 73,769 patients with HF (53% HFrEF, 25% HFmrEF, and 22% HFpEF; 38% ischemic, 8% valvular, 25% hypertensive, and 29% other), ischemic etiology was independently associated with HFrEF and HFmrEF, while hypertensive and valvular etiologies were associated with HFpEF. In HFrEF, ischemic etiology was associated with the primary outcome in comparison with all other 3 etiologies. In HFmrEF, hypertensive etiology was associated with first HF hospitalization (HR: 1.10 [95% CI: 1.03-1.19]). In HFpEF, valvular etiology was associated with first HF hospitalization (HR: 1.11 [95% CI: 1.02-1.22]).</div></div><div><h3>Conclusions</h3><div>Ischemic etiology was dominant in HFrEF and HFmrEF, while valvular and hypertensive etiologies dominated in HFpEF. Etiologies most associated with death/HF hospitalization were ischemic in HFrEF, hypertensive in HFmrEF, and valvular in HFpEF.</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102491"},"PeriodicalIF":10.3,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144291049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Associations of Cardiac, Pulmonary, Arterial, and Muscle Physiological Parameters and Biomarkers With the Incidence of HFpEF and HFrEF","authors":"Fernando R. Giugni MD, PhD ,&nbsp;Yimin Yang MS ,&nbsp;Brian Claggett PhD ,&nbsp;Victoria Lamberson PhD ,&nbsp;Scott D. Solomon MD ,&nbsp;Pamela L. Lutsey PhD, MPH ,&nbsp;Dalane W. Kitzman MD ,&nbsp;Chiadi Ndumele MD, PhD, MHS ,&nbsp;Thomas H. Mosley PhD ,&nbsp;Patricia P. Chang MD, MHS ,&nbsp;Leo F. Buckley PharmaD, MPH ,&nbsp;Ron C. Hoogeveen PhD ,&nbsp;Christie M. Ballantyne MD ,&nbsp;Amil M. Shah MD, MPH","doi":"10.1016/j.jchf.2025.02.029","DOIUrl":"10.1016/j.jchf.2025.02.029","url":null,"abstract":"<div><h3>Background</h3><div>Postulated differences in heart failure with preserved ejection fraction (HFpEF) compared with heart failure with reduced ejection fraction (HFrEF) include greater contributions of noncardiac dysfunction to HFpEF.</div></div><div><h3>Objectives</h3><div>This study aims to evaluate associations of cardiac and noncardiac physiological measures with prevalent and incident HFpEF and HFrEF.</div></div><div><h3>Methods</h3><div>Among 5,484 Atherosclerosis Risk in Communities study participants attending the fifth visit (2011-2013), this study assessed associations of cardiac structure and function by echocardiogram, pulmonary function by spirometry, arterial stiffness by pulse wave velocity, muscle strength by handgrip, fat mass by bioimpedance, inflammation by plasma biomarkers, and renal function with prevalent and incident adjudicated HFpEF (ejection fraction [EF] ≥50%) and HFrEF (EF &lt;50%) by using adjusted logistic and Cox models.</div></div><div><h3>Results</h3><div>Mean age was 75 ± 5 years, 59% were women, left ventricular (LV) EF was 65% ± 7%, 246 patients had prevalent HFpEF, and 81 patients had prevalent HFrEF. Worse LV and right ventricular systolic function and larger LV size were associated more strongly with prevalent HFrEF; a higher body mass index (BMI) was associated more strongly with prevalent HFpEF. Among heart failure–free participants, 220 incident HFpEF and 187 HFrEF events occurred over a median 7 years (range: 6-8 years) of follow-up. Worse LV systolic function and larger LV size were more strongly associated with incident HFrEF, whereas higher pulmonary artery systolic pressure demonstrated a greater association with incident HFpEF. Most noncardiac dysfunctions, including greater BMI, fat mass, and systemic inflammation, showed similar magnitudes of association with incident HFpEF and HFrEF.</div></div><div><h3>Conclusions</h3><div>Among older adults, subclinical LV systolic dysfunction and remodeling differentially predicted the risk of incident HFrEF, whereas diastolic and most noncardiac dysfunctions were associated similarly with both incident HFpEF and HFrEF.</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102483"},"PeriodicalIF":10.3,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144280687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary Epidemiology, Management, and In-Hospital Outcomes of Acute Myocarditis","authors":"Claire Bouleti MD, PhD ,&nbsp;Theodora Bejan-Angoulvant MD, PhD ,&nbsp;Clement Servoz MD ,&nbsp;Ehmer Carsten MD ,&nbsp;Thibaud Genet MD ,&nbsp;Julien Ternacle MD, PhD ,&nbsp;Jean-François Deux MD, PhD ,&nbsp;Etienne Puymirat MD, PhD ,&nbsp;Elie Mousseaux MD, PhD ,&nbsp;Benjamin Alos MD ,&nbsp;Rodrigue Garcia MD, PhD ,&nbsp;Guillaume Bonnet MD ,&nbsp;Alexis Jacquier MD, PhD ,&nbsp;Benoit Lattuca MD, PhD ,&nbsp;Olivier Huttin MD, PhD ,&nbsp;Mariama Akodad MD, PhD ,&nbsp;Alban Redheuil MD, PhD ,&nbsp;Denis Angoulvant MD, PhD ,&nbsp;Phalla Ou MD, PhD ,&nbsp;Cyrille Boulogne","doi":"10.1016/j.jchf.2025.03.038","DOIUrl":"10.1016/j.jchf.2025.03.038","url":null,"abstract":"<div><h3>Background</h3><div>Despite a frequently favorable evolution during the initial phase, acute myocarditis (AM) remains associated with heart failure and ventricular arrhythmia. There are no large prospective databases to provide robust results.</div></div><div><h3>Objectives</h3><div>The aim of this study was to describe baseline characteristics, real-life management, in-hospital outcomes, and determinants of prognosis in a large cohort of patients with AM admitted to cardiology, with a comparison of patients with and without initial severity criteria.</div></div><div><h3>Methods</h3><div>MyocarditIRM (French National Observatory Tracking Viral Myocarditis: Mortality, Cardiovascular Events, Sequels on [Magnetic Resonance Imaging] MRI) is a multicenter prospective observational study of patients with AM confirmed by cardiac magnetic resonance. Patients initially admitted to the intensive care unit or those who died before cardiac magnetic resonance–confirmed diagnosis were not included.</div></div><div><h3>Results</h3><div>In total, 803 consecutive hospitalized patients were enrolled at 49 participating centers between May 2016 and February 2019. The median age was 31 years (Q1-Q3: 23-41 years), and 82% were men. Chest pain was the most frequent symptom (93%), and 112 patients (14%) had severity criteria upon admission (left ventricular ejection fraction &lt;50%, severe ventricular arrythmia, high-degree atrioventricular block, or cardiogenic shock). ST-segment elevation was observed in 49% of patients. Overall, 64 patients (8%) experienced in-hospital complications, defined as a composite of death; left ventricular ejection fraction ≤40%; sustained ventricular or supraventricular arrythmia; cardiogenic shock; and need for mechanical circulatory support, inotropic drugs, temporary cardiac pacing, pacemaker, or cardiac defibrillator implantation. Patients with severity criteria at admission were 10 times more likely to experience in-hospital complications.</div></div><div><h3>Conclusions</h3><div>This prospective cohort represents the largest AM database worldwide. Although the recruitment process likely led to a selection of patients with lower risk AM, 8% experienced in-hospital complications, the major prognosis factor being severity criteria upon admission. (French National Observatory Tracking Viral Myocarditis: Mortality, Cardiovascular Events, Sequels on (Magnetic Resonance Imaging) MRI; <span><span>NCT02717143</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14687,"journal":{"name":"JACC. Heart failure","volume":"13 8","pages":"Article 102492"},"PeriodicalIF":10.3,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144280688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}