Israel Journal of Chemistry最新文献_第2页

Facile Synthesis of Pentafluoroorthotelluric Acid 五氟正碲酸的简易合成

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-07-29 DOI: 10.1002/ijch.70041

Claire Simon, Simon Steinhauer, Anja Wiesner, Sebastian Riedel

引用次数: 0

Exploring the Potential of Pair Distribution Function Analysis From Laboratory X-Ray Diffractometers for Metal–Organic Frameworks 从实验室x射线衍射仪探索金属-有机框架的对分布函数分析的潜力

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-07-09 DOI: 10.1002/ijch.70040

Ignacio Romero-Muñiz, Javier Pérez-Carvajal, Fátima Esteban-Betegón, Felipe Gándara

{"title":"Exploring the Potential of Pair Distribution Function Analysis From Laboratory X-Ray Diffractometers for Metal–Organic Frameworks","authors":"Ignacio Romero-Muñiz, Javier Pérez-Carvajal, Fátima Esteban-Betegón, Felipe Gándara","doi":"10.1002/ijch.70040","DOIUrl":"https://doi.org/10.1002/ijch.70040","url":null,"abstract":"Pair distribution function (PDF) analysis provides direct access to the local and intermediate-range structure of metal–organic frameworks (MOFs), complementing the average structural information obtained from conventional diffraction. Despite its growing importance, PDF analysis has remained largely associated with synchrotron radiation. Here, we show that meaningful PDF data can also be obtained in-house using a laboratory diffractometer equipped with an Ag source and an optimized total scattering strategy. Using representative MOF case studies, including crystalline and amorphous ZIF-8, a flexible Fe-MIL-88 framework, the comparison of HKUST-1 with a molecular analog of its paddle-wheel unit, and measurements from very small sample quantities, we demonstrate the ability of laboratory-based PDF analysis to probe local connectivity, framework flexibility, inorganic building units, and structural integrity under limited sample conditions. Although laboratory measurements do not replace synchrotron total scattering for more demanding structural problems, they offer an accessible and valuable complementary route for the routine structural investigation of MOFs.","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"66 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijch.70040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148466786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Potential of Pair Distribution Function Analysis From Laboratory X-Ray Diffractometers for Metal–Organic Frameworks 从实验室x射线衍射仪探索金属-有机框架的对分布函数分析的潜力

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-07-09 DOI: 10.1002/ijch.70040

Ignacio Romero-Muñiz, Javier Pérez-Carvajal, Fátima Esteban-Betegón, Felipe Gándara

{"title":"Exploring the Potential of Pair Distribution Function Analysis From Laboratory X-Ray Diffractometers for Metal–Organic Frameworks","authors":"Ignacio Romero-Muñiz, Javier Pérez-Carvajal, Fátima Esteban-Betegón, Felipe Gándara","doi":"10.1002/ijch.70040","DOIUrl":"https://doi.org/10.1002/ijch.70040","url":null,"abstract":"Pair distribution function (PDF) analysis provides direct access to the local and intermediate-range structure of metal–organic frameworks (MOFs), complementing the average structural information obtained from conventional diffraction. Despite its growing importance, PDF analysis has remained largely associated with synchrotron radiation. Here, we show that meaningful PDF data can also be obtained in-house using a laboratory diffractometer equipped with an Ag source and an optimized total scattering strategy. Using representative MOF case studies, including crystalline and amorphous ZIF-8, a flexible Fe-MIL-88 framework, the comparison of HKUST-1 with a molecular analog of its paddle-wheel unit, and measurements from very small sample quantities, we demonstrate the ability of laboratory-based PDF analysis to probe local connectivity, framework flexibility, inorganic building units, and structural integrity under limited sample conditions. Although laboratory measurements do not replace synchrotron total scattering for more demanding structural problems, they offer an accessible and valuable complementary route for the routine structural investigation of MOFs.","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"66 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijch.70040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148466784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chiral Mesoporous Organosilica Hierarchical Hollow Nanostructures for Enantioselective Adsorption 手性介孔有机硅分级中空纳米结构对映选择性吸附

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-07-09 DOI: 10.1002/ijch.70039

Reema Siam, David Avnir, Raed Abu-Reziq

{"title":"Chiral Mesoporous Organosilica Hierarchical Hollow Nanostructures for Enantioselective Adsorption","authors":"Reema Siam, David Avnir, Raed Abu-Reziq","doi":"10.1002/ijch.70039","DOIUrl":"https://doi.org/10.1002/ijch.70039","url":null,"abstract":"The synthesis of a new class of chiral mesoporous organosilica hollow nanostructures with tunable architectures is reported using a controlled stepwise sol–gel approach. By modulating the sequence of precursor addition, both yolk-shell and multishelled hollow nanospheres are obtained, enabling precise spatial control over the distribution of chiral and achiral domains. The chiral framework is constructed from enantiopure bridged organosilane monomers, synthesized by reacting 3-isocyanatopropyltriethoxysilane with either (R,R)- or (S,S)-diphenylethane-1,2-diamine (DPEN) or cyclohexane-1,2-diamine (DAC). The achiral component is formed from a mixture of tetraethyl orthosilicate (TEOS) and 1,2-bis(triethoxysilyl)ethane (BTSE), providing structural stability and mesoporosity. By controlling the sequence of precursor addition during the sol–gel process, the chiral framework is selectively introduced at different stages of formation, allowing precise spatial positioning within the hollow architecture. The resulting materials exhibit well-defined morphology, high organic content, and accessible mesoporosity. Enantioselective adsorption studies using tryptophan (Trp) reveal that the spatial location of the chiral framework is a decisive factor in chiral recognition. The highest enantioselectivity is observed when the chiral domains are confined within the interior of the structure, where the nanoconfined environment enhances host–guest interactions, yielding selectivity factors up to 7.0.","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"66 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148466785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chiral Mesoporous Organosilica Hierarchical Hollow Nanostructures for Enantioselective Adsorption 手性介孔有机硅分级中空纳米结构对映选择性吸附

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-07-09 DOI: 10.1002/ijch.70039

Reema Siam, David Avnir, Raed Abu-Reziq

{"title":"Chiral Mesoporous Organosilica Hierarchical Hollow Nanostructures for Enantioselective Adsorption","authors":"Reema Siam, David Avnir, Raed Abu-Reziq","doi":"10.1002/ijch.70039","DOIUrl":"https://doi.org/10.1002/ijch.70039","url":null,"abstract":"The synthesis of a new class of chiral mesoporous organosilica hollow nanostructures with tunable architectures is reported using a controlled stepwise sol–gel approach. By modulating the sequence of precursor addition, both yolk-shell and multishelled hollow nanospheres are obtained, enabling precise spatial control over the distribution of chiral and achiral domains. The chiral framework is constructed from enantiopure bridged organosilane monomers, synthesized by reacting 3-isocyanatopropyltriethoxysilane with either (R,R)- or (S,S)-diphenylethane-1,2-diamine (DPEN) or cyclohexane-1,2-diamine (DAC). The achiral component is formed from a mixture of tetraethyl orthosilicate (TEOS) and 1,2-bis(triethoxysilyl)ethane (BTSE), providing structural stability and mesoporosity. By controlling the sequence of precursor addition during the sol–gel process, the chiral framework is selectively introduced at different stages of formation, allowing precise spatial positioning within the hollow architecture. The resulting materials exhibit well-defined morphology, high organic content, and accessible mesoporosity. Enantioselective adsorption studies using tryptophan (Trp) reveal that the spatial location of the chiral framework is a decisive factor in chiral recognition. The highest enantioselectivity is observed when the chiral domains are confined within the interior of the structure, where the nanoconfined environment enhances host–guest interactions, yielding selectivity factors up to 7.0.","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"66 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148466783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

R17 Drives Heparan Sulfate Clearance via Endolysosomal Trafficking. R17通过内溶酶体运输驱动硫酸肝素清除。

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-07-01 Epub Date: 2026-05-20 DOI: 10.1002/ijch.70016

Pranali Bedekar, Alexander Lin, Abigail E Reeves, Meg Critcher, Gil-Suk Yang, Sean Hui, Daved H Fremont, Mia L Huang

{"title":"R17 Drives Heparan Sulfate Clearance via Endolysosomal Trafficking.","authors":"Pranali Bedekar, Alexander Lin, Abigail E Reeves, Meg Critcher, Gil-Suk Yang, Sean Hui, Daved H Fremont, Mia L Huang","doi":"10.1002/ijch.70016","DOIUrl":"10.1002/ijch.70016","url":null,"abstract":"Heparan sulfate (HS) proteoglycans are information-rich macromolecules that can orchestrate extracellular signaling and cargo uptake across diverse cellular contexts. Ligands that can engage cell surface HS possess significant potential as probes to investigate or manipulate cell-matrix interactions. Here, we show that R17, an HS-binding protein from the rodent herpesvirus Peru, actively remodels the glycocalyx of pancreatic cancer cells. Recombinant R17 bound heparin in vitro and associated with the surface of pancreatic cancer cells to promote the dose-dependent clearance of HS via trafficking to lysosomes. R17 also reduced wound closure without detectable cytotoxicity, indicative of the ability of R17 to suppress cellular migration. Notably, HS depletion persisted upon cation-independent mannose-6-phosphate receptor knockdown, suggesting that clearance is independent of this mechanism. These findings identify R17 as an exogenous HS-binding protein that can drive HS clearance via endolysosomal trafficking and suggest an alternative approach to modulate HS-dependent functions.","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"66 4","pages":"e70016"},"PeriodicalIF":2.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13557213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148919762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From Prebiotic Catalysts to Modern Applications: How Early Catalysts Inspire Today's Innovations 从益生元催化剂到现代应用：早期催化剂如何激发今天的创新

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-06-29 DOI: 10.1002/ijch.70038

Omer Agazani, Meital Reches

{"title":"From Prebiotic Catalysts to Modern Applications: How Early Catalysts Inspire Today's Innovations","authors":"Omer Agazani, Meital Reches","doi":"10.1002/ijch.70038","DOIUrl":"https://doi.org/10.1002/ijch.70038","url":null,"abstract":"Catalysis underlies both the emergence of early chemical systems and the development of modern functional materials. While contemporary catalysts often rely on highly optimized active sites and precise molecular control, prebiotic chemistry demonstrates that catalytic activity can arise from chemically simple components operating under harsh and poorly regulated conditions. In this review, prebiotic catalytic systems are examined as a source of general molecular features rather than as isolated reactions specific to early Earth. Catalytic functions exhibited by small molecules, short peptides, metal ions, minerals, and hybrid assemblies are sueveyed. Molecular features that support emergent catalytic behavior, including reactive functional groups, self-assembly, coordination-driven hybridization, and material-level robustness are highlighted. It is shown how these same features are increasingly reflected in modern catalytic materials, including supramolecular systems, self-assembled catalysts, and coordination-based hybrid architectures. By emphasizing organization and cooperation over molecular complexity, this review provides a conceptual framework linking prebiotic catalysis with the rational design of functional materials.","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"66 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijch.70038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffusion and Gas Transport in Reticular Materials 网状材料中的扩散和气体输运

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-06-29 DOI: 10.1002/ijch.70037

T. Grant Glover, Thomas Lassitter

引用次数: 0

From Prebiotic Catalysts to Modern Applications: How Early Catalysts Inspire Today's Innovations 从益生元催化剂到现代应用：早期催化剂如何激发今天的创新

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-06-29 DOI: 10.1002/ijch.70038

Omer Agazani, Meital Reches

{"title":"From Prebiotic Catalysts to Modern Applications: How Early Catalysts Inspire Today's Innovations","authors":"Omer Agazani, Meital Reches","doi":"10.1002/ijch.70038","DOIUrl":"https://doi.org/10.1002/ijch.70038","url":null,"abstract":"Catalysis underlies both the emergence of early chemical systems and the development of modern functional materials. While contemporary catalysts often rely on highly optimized active sites and precise molecular control, prebiotic chemistry demonstrates that catalytic activity can arise from chemically simple components operating under harsh and poorly regulated conditions. In this review, prebiotic catalytic systems are examined as a source of general molecular features rather than as isolated reactions specific to early Earth. Catalytic functions exhibited by small molecules, short peptides, metal ions, minerals, and hybrid assemblies are sueveyed. Molecular features that support emergent catalytic behavior, including reactive functional groups, self-assembly, coordination-driven hybridization, and material-level robustness are highlighted. It is shown how these same features are increasingly reflected in modern catalytic materials, including supramolecular systems, self-assembled catalysts, and coordination-based hybrid architectures. By emphasizing organization and cooperation over molecular complexity, this review provides a conceptual framework linking prebiotic catalysis with the rational design of functional materials.","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"66 4","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijch.70038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148386530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffusion and Gas Transport in Reticular Materials 网状材料中的扩散和气体输运

IF 2.1 4区化学

Israel Journal of Chemistry Pub Date : 2026-06-29 DOI: 10.1002/ijch.70037

T. Grant Glover, Thomas Lassitter

引用次数: 0