Rosaria Ciriminna, Cristina Della Pina, Rafael Luque, Mario Pagliaro
{"title":"Mentoring Doctoral Students in the Chemical Sciences","authors":"Rosaria Ciriminna, Cristina Della Pina, Rafael Luque, Mario Pagliaro","doi":"10.1002/ijch.202512004","DOIUrl":"https://doi.org/10.1002/ijch.202512004","url":null,"abstract":"<p>The relevance of effective mentoring of doctoral students in the chemical sciences is now widely recognized. However, the scholarly literature on the topic is virtually non-existent, and most approaches to faculty education on mentoring are based on “tips” and “guidelines. Following the analysis of current mentorship practices, we suggest a new approach based on evidence resulting from surveys of doctoral students, and on theory derived from studies in social and human sciences.</p>","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"65 4-5","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"30 Years of Quantum Dot Research – My Personal Journey","authors":"Uri Banin","doi":"10.1002/ijch.202512003","DOIUrl":"https://doi.org/10.1002/ijch.202512003","url":null,"abstract":"<p>The 2023 Nobel Prize awarded to Moungi G. Bawendi, Louis E. Brus, and Alexei Ekimov “for the discovery and synthesis of quantum dots” (QDs) marks a milestone in the field to which I devoted the past 30-years of my career. In this perspective, I reflect on key concepts and directions in my research journey. I began by exploring the “artificial atom” nature of QDs while advancing the development of III-V QDs. Shape control, particularly in rods, captured my attention due to its impact on dimensionality related properties. I also discovered semiconductor-metal hybrid nanocrystals and uncovered synergetic effects, highlighting their transformative role in photocatalysis and heavy doping. My work extended to QD applications in displays and, more recently, to forming coupled QD molecules, continuing the artificial atom theme. I conclude by outlining future directions and challenges, envisioning a bright future for this vibrant field at the intersection of materials and physical chemistry.</p>","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"65 4-5","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conductive Nanomaterials in Printed Electronics","authors":"Alexander Kamyshny, Shlomo Magdassi","doi":"10.1002/ijch.202512002","DOIUrl":"https://doi.org/10.1002/ijch.202512002","url":null,"abstract":"<p>Printed electronics is based on the application of 2D and 3D printing technologies to fabricate electronic devices. To fabricate the printed electronic 2D and 3D devices with the required performance, it is necessary to properly select and tailor the conductive inks, which are often composed of nanomaterials, The main nanomaterials in conductive inks for 2D and 3D printed electronics contain conductive nanomaterials such as metal nanoparticles (NPs) and nanowires and carbon based nanomaterials: carbon black, graphene sheets, and carbon nanotubes (CNTs). All these materials were successfully applied for the fabrication of various electronic devices such as electrical circuits, transparent electrodes, flexible thin film transistors, RFID antennas, photovoltaic devices, and flexible touch panels. In this paper, we focus on the basic properties of these nanomaterials, in view of their application in conductive inks, on obtaining conductive patterns by 2D and 3D printing, and on various methods of post-printing treatment. In the last section, a perspective on future needs and applications will be presented, including emerging technologies.</p>","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"65 4-5","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144197002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Getting in Shape: Targeting the Etiology of Protein Misfolding Diseases – Celebrating Jeffery Kelly's Pioneering Work","authors":"Lars Plate, Joseph C. Genereux","doi":"10.1002/ijch.202481231","DOIUrl":"https://doi.org/10.1002/ijch.202481231","url":null,"abstract":"<p>We are excited to share this special issue dedicated to Jeffery Kelly, commemorating his 2023 Wolf Prize in Chemistry. This award recognizes his pioneering research accomplishments, which have dramatically changed our fundamental understanding of how proteins (mis)fold in vitro and in vivo while at the same time leveraging those discoveries to change the lives of patients across the globe. The award specifically refers to the latter: “for developing a clinical strategy to ameliorate pathological protein aggregation”. This is exemplified by the development of Tafamidis,<span><sup>1</sup></span> the first clinically approved molecule to treat a disease of protein misfolding.<span><sup>2, 3</sup></span></p><p>Jeff's discovery that protein misfolding of transthyretin (TTR) is an obligate step prior to protein aggregation<span><sup>4</sup></span> established that preventing the accumulation of misfolded proteins can block disease pathology. Rigorous biochemical and biophysical characterization established that transthyretin tetramer dissociation into monomers is the rate-limiting step that initiates protein misfolding.<span><sup>5</sup></span> This critical insight motivated the development of small molecules that could stabilize the native conformation of TTR,<span><sup>6</sup></span> culminating in the development and clinical approval of Tafamidis.</p><p>Later, Jeff and his collaborators introduced the idea of protein homeostasis (or proteostasis).<span><sup>7</sup></span> Protein folding and maturation into its native structure is not only governed by the intrinsic stability of each polypeptide chain, but in a cellular environment, the large ensemble of molecular chaperones, co-chaperones, other protein quality factors, and their interacting activities maintain the integrity of the proteome for cellular and organismal health. Importantly, dysregulation of the proteostasis network can lead to insufficient protein folding capacity and accumulation of misfolded proteins, which is associated with various disease states, ranging from neurodegeneration to diabetes and cancer.<span><sup>8, 9</sup></span></p><p>Several reviews and articles in this special issue address how a detailed understanding of protein misfolding and the proteostasis network can be leveraged in therapeutic development. These contributions highlight the impact that Jeff's work has had on the broader chemistry and biology research community.</p><p>Although transthyretin amyloidosis was once thought to be rare, we now know that millions of people are carriers of likely pathogenic variants.<span><sup>10</sup></span> Following the success of Tafamidis, there are now many emerging approaches for therapeutic intervention in this disease class, as reviewed by Per Hammarström in this issue.<span><sup>11</sup></span> Another class of protein associated with systemic amyloidosis is immunoglobulin light chain, which lead to AL amyloidosis. Gareth Morgan reviews how both amyloidogenicity and ","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"64 12","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijch.202481231","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cover Picture: (Isr. J. Chem. 12/2024)","authors":"","doi":"10.1002/ijch.202481201","DOIUrl":"https://doi.org/10.1002/ijch.202481201","url":null,"abstract":"<p>The cover art depicts Jeffery Kelly's pioneering development of Tafamidis as a clinical strategy to ameliorate transthyretin protein aggregation (in the center). Surrounding images highlight examples from this special issue of how his work has influenced other approaches to characterize and target the etiology of diverse protein misfolding diseases.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"64 12","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijch.202481201","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cover Picture: (Isr. J. Chem. 10-11/2024)","authors":"","doi":"10.1002/ijch.202481001","DOIUrl":"https://doi.org/10.1002/ijch.202481001","url":null,"abstract":"<p>The cover image shows the logo of the 15th International Conference on Quasicrystals, held at Tel Aviv University in June 2023. The logo depicts the hexagonal Star of David. The background depicts a hexagonal quasiperiodic tiling, whose construction and characterization are the focus of the Review by Coates et al. in this volume. Such aperiodic yet perfectly ordered trigonal and hexagonal tilings served to study various experimental systems, such as the 3-fold surfaces of icosahedral quasicrystals and 6-fold bilayer graphene.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":14686,"journal":{"name":"Israel Journal of Chemistry","volume":"64 10-11","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ijch.202481001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142861809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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