Iranian Journal of Public Health最新文献_第2页

Effect of Self-Leadership, Resilience, and Communication Ability on the Intention to Keep Nursing Job among Korean Nurses. 自我领导、心理韧性和沟通能力对韩国护士继续护理工作意愿的影响。

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18421

Yeon-Ju Kim, Yeon-Ran Hong, Ho-Jin Lee

{"title":"Effect of Self-Leadership, Resilience, and Communication Ability on the Intention to Keep Nursing Job among Korean Nurses.","authors":"Yeon-Ju Kim, Yeon-Ran Hong, Ho-Jin Lee","doi":"10.18502/ijph.v54i4.18421","DOIUrl":"https://doi.org/10.18502/ijph.v54i4.18421","url":null,"abstract":"Background: We investigated the effects of self-leadership, resilience, and communication ability on the intention to keep one's nursing job among Korean nurses.Methods: Data were collected from 245 nurses from hospitals in Jeollanam-do Province, Republic of Korea in 2022. The collected data were analyzed using independent t-tests, one-way analyses of variance, post-hoc tests, Pearson's correlation coefficients, and stepwise multiple regression.Results: The intention to keep one's nursing job was positively correlated with self-leadership (r=0.34, P<0.001), resilience (r=0.45, P<0.001), and communication ability (r=0.34, P<0.001). Positive correlations were also found between self-leadership and resilience (r=0.65, P<0.001), communication ability and self-leadership (r=0.49, P<0.001), and resilience and communication ability (r=0.69, P<0.001). Furthermore, resilience (β=0.27, P=0.001), age (β=0.26, P<0.001), welfare satisfaction (β=0.17, P=0.003), and communication ability (β=0.16, P=0.031) influenced nurses' intention to keep their jobs. The regression model was statistically significant (F=24.94, P<0.001), and the explanatory power was 29.4%.Conclusion: Nurses' intention to keep their jobs can be strengthened by improving their treatment, welfare, and communication abilities. Accordingly, educational programs are needed to create an efficient nursing environment and improve nurses' resilience and communication abilities.","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 4","pages":"820-829"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival Rate of Breast Cancer and Related Factors in Iran: A 27-Year Follow-Up. 伊朗乳腺癌生存率及相关因素：27年随访

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18426

Mohammad Esmaeil Akbari, Atieh Akbari, Mohammad Akbari, Maryam Khayamzadeh

{"title":"Survival Rate of Breast Cancer and Related Factors in Iran: A 27-Year Follow-Up.","authors":"Mohammad Esmaeil Akbari, Atieh Akbari, Mohammad Akbari, Maryam Khayamzadeh","doi":"10.18502/ijph.v54i4.18426","DOIUrl":"https://doi.org/10.18502/ijph.v54i4.18426","url":null,"abstract":"Background: Several factors can affect the survival of patients with breast cancer (BC). We estimated BC patients' 5-, 10-, and 15-year survival rates and influential factors in a single medical center during the last three decades.Methods: We enrolled patients diagnosed with BC managed in the Cancer Research Center of Shahid Beheshti University of Medical Sciences, Tehran, Iran from 1991 to 2018. All patients were followed to check the patients' status. The data were analyzed regarding demographic, clinical, pathological, and molecular biology characteristics. Descriptive and survival analyses were performed. Kaplan Meier and Cox proportional hazards regression models were used for survival analysis.Results: Overall, 4, 429 women were included. The mean age was 49. 11 (±11. 98) yr. Nearly 70% of the patients had high school degrees. Totally, 35% of patients were diagnosed in the advanced stages of BC. Estrogen Receptor (ER), Progesterone Receptor (PR), and human epidermal growth factor receptor 2 (HER2) were positive in 72. 50%, 66. 90%, and 16. 20% of the cases, respectively. About 11. 6% of patients died. The overall 5-, 10-, and 15-year survival rates of BC were 90%, 83%, and 75%, respectively. In the Cox proportional hazard analysis, the survival rate was affected by literacy level, positive lymph nodes, lymphovascular invasion, ER, tumor size, and pathological grade.Conclusion: This is the first report on the 15-year survival rate of BC and its influential factors, from a medical center in Iran. The results were acceptable and comparable with those of developed countries due to scientific protocols, teamwork, and effective follow-up in a developing country.","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 4","pages":"870-880"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Research Progress of Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusions and Tropomyosin Receptor Kinase (TRK) Inhibitors: A Narrative Review. 神经营养型酪氨酸受体激酶（NTRK）基因融合及原肌球蛋白受体激酶（TRK）抑制剂的研究进展

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18410

Jielin Li, Yuan Liang

{"title":"The Research Progress of Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusions and Tropomyosin Receptor Kinase (TRK) Inhibitors: A Narrative Review.","authors":"Jielin Li, Yuan Liang","doi":"10.18502/ijph.v54i4.18410","DOIUrl":"https://doi.org/10.18502/ijph.v54i4.18410","url":null,"abstract":"NTRK gene is responsible for encoding TRK, which consists of three family members: NTRK1, NTRK2, and NTRK3. These family members encode different proteins known as TRKA, TRKB, and TRKC, respectively. NTRK fusion genes are the clearest driving factor for carcinogenesis. NTRK gene fusion detection and TRK inhibitors are effective measures for the treatment of malignant tumors. The development of anti-tumor drugs targeting TRK proteins has been favored by various scientific research institutions and pharmaceutical companies. The first-generation TRK inhibitors, larotrectinib and entrectinib, have been approved for the treatment of pediatric and adult patients with metastatic or locally advanced solid tumors harboring NTRK fusion proteins, demonstrating remarkable anticancer efficacy in clinical settings. However, the issue of acquired resistance to TRK inhibitors has emerged. Currently, efforts are underway to develop next-generation TRK inhibitors based on sequence, structural, and kinetic methodologies, as well as to explore the intracellular signaling pathways of TRK and the mechanisms underlying resistance. The main focus of this review was to discuss the fusion of NTRK genes and the application of TRK inhibitor treatment.","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 4","pages":"710-722"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case Study on Trends in Acute Respiratory Illnesses and Influenza in Singapore: Pre-, during, and Post-COVID-19 Pandemic. 新加坡急性呼吸道疾病和流感趋势的案例研究：covid -19大流行之前、期间和之后。

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18417

Kee Leng Chua, Hwang Ching Chan, Jyoti Somani, See Ming Lim

{"title":"A Case Study on Trends in Acute Respiratory Illnesses and Influenza in Singapore: Pre-, during, and Post-COVID-19 Pandemic.","authors":"Kee Leng Chua, Hwang Ching Chan, Jyoti Somani, See Ming Lim","doi":"10.18502/ijph.v54i4.18417","DOIUrl":"https://doi.org/10.18502/ijph.v54i4.18417","url":null,"abstract":"Background: We investigated trends in acute respiratory illnesses and influenza activity in Singapore throughout the COVID-19 pandemic.Methods: Publicly available data from the Ministry of Health, Singapore was used to estimate the number of daily acute respiratory illnesses (ARI) and influenza cases between 2019 and Jun 2023. Overseas travel activity was obtained from the Department of Statistics, Singapore. Trends in ARI and influenza activity during different phases of the COVID-19 pandemic with changes in key public health measures were compared.Results: Pre-pandemic influenza activity exhibited seasonal peaks in Jan and Jul, with daily estimated cases exceeding 40 during these periods. During the early pandemic, influenza cases declined sharply to close to zero and remained at these levels until mid-2022, even after public health measures were eased. ARI cases followed a similar initial decline but gradually returned to pre-pandemic levels by 2023, with peaks occurring outside the usual seasonal pattern. These trends corresponded with phases of public health measures, including mask-wearing and travel restrictions.Conclusion: Several hypotheses for these contrasting trends were explored, including increased public health awareness, higher influenza vaccination rates, and potential virus-virus interactions.","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 4","pages":"795-800"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Breathing Meditation Program on the Lung Function in Physically Disabled Elderly Individuals. 呼吸冥想计划对身体残疾老年人肺功能的影响。

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18428

Na-Hyeon Kim

引用次数: 0

Comparing the Effects of Glucose-Fructose versus Glucose on the Oxidation Rate: A Systematic Review and Meta-Analysis. 比较葡萄糖-果糖和葡萄糖对氧化速率的影响：一项系统综述和荟萃分析。

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18411

Zahra Gohari Dezfuli, Minoo Hasan Rashedi, Fatemeh Naeini, Sakineh Shab-Bidar, Mohammadhossein Pourgharib-Shahi, Xueying Zhang, Elaheh Dehghani, Kurosh Djafarian

{"title":"Comparing the Effects of Glucose-Fructose versus Glucose on the Oxidation Rate: A Systematic Review and Meta-Analysis.","authors":"Zahra Gohari Dezfuli, Minoo Hasan Rashedi, Fatemeh Naeini, Sakineh Shab-Bidar, Mohammadhossein Pourgharib-Shahi, Xueying Zhang, Elaheh Dehghani, Kurosh Djafarian","doi":"10.18502/ijph.v54i4.18411","DOIUrl":"https://doi.org/10.18502/ijph.v54i4.18411","url":null,"abstract":"Background: Numerous studies have aimed to compare the effects of glucose (Glu) consumption with those of glucose-fructose (Glu-Fru) consumption on oxidation rates during exercise. However, divergent outcomes have surfaced due to variations in exercise protocols and concurrent substance ingestion, leading to a lack of consensus. This systematic review and meta-analysis investigated the comparative effects of Glu and Glu-Fru on total carbohydrate oxidation, endogenous carbohydrate oxidation, exogenous carbohydrate oxidation, and total fat oxidation rates during exercise.Methods: A systematic search of PubMed, Scopus, and Web of Science databases up to February 2023. The search yielded 14 randomized controlled trials involving 125 endurance athletes.Results: The meta-analyses revealed that Glu supplementation significantly increased total carbohydrate oxidation (WMD: 0.21 g/min) compared to Glu-Fru. Endogenous carbohydrate oxidation significantly increased with Glu (WMD: -0.12), while Glu-Fru led to increased exogenous carbohydrate oxidation (WMD: 0.27 g/min). Total fat oxidation decreased with Glu-Fru (WMD: -0.06 g/min).Conclusion: By investigating athletic nutrition complexities, our findings shed light on metabolic responses to Glu-Fru versus Glu supplementation. Tailoring hydration strategies, athletes should select an optimal Glu-Fru to Glu ratio for maximal oxidation and enhanced performance. Future research could explore dose-response relationships for optimal metabolic benefits during exercise.","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 4","pages":"723-738"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045866/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Prevalence of Neisseria gonorrhoeae in Women with Genitourinary Symptoms in Tehran, Iran. 探讨在伊朗德黑兰有泌尿生殖系统症状的妇女淋病奈瑟菌的流行。

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18424

Narjes Noori Goodarzi, Shaghayegh Zafar, Naghmeh Pourmand, Soheila Ajdary, Mir Saeed Yekaninejad, Mohammad Reza Pourmand, Farzad Badmasti

{"title":"Exploring the Prevalence of Neisseria gonorrhoeae in Women with Genitourinary Symptoms in Tehran, Iran.","authors":"Narjes Noori Goodarzi, Shaghayegh Zafar, Naghmeh Pourmand, Soheila Ajdary, Mir Saeed Yekaninejad, Mohammad Reza Pourmand, Farzad Badmasti","doi":"10.18502/ijph.v54i4.18424","DOIUrl":"https://doi.org/10.18502/ijph.v54i4.18424","url":null,"abstract":"Background: Neisseria gonorrhoeae, the second most common sexually transmitted infection (STI) worldwide, affects one million people daily. We aimed to investigate the prevalence of gonorrhea in females with genital infections in Tehran, Iran.Methods: First, a bioinformatic study was conducted to identify a conserved and high-prevalent gene marker for detection of N. gonorrhoeae. One desirable marker was selected and a pair of specific primers was designed to amplify it. The reliability of the primer pair was evaluated in silico and in vitro. Subsequently, 172 patients with genitourinary symptoms were enrolled and an endocervical swab specimen was obtained from each patient to evaluate the presence of N. gonorrhoeae in clinical specimens using the specific primers.Results: Restriction endonuclease subunit S (resS, WP_003687768.1) was selected as a specific detection marker. The designed primer pair targeting resS showed specific and reliable detection of N. gonorrhoeae in silico and in vitro. Out of 172 clinical samples, seven (4.06%) cases were infected by N. gonorrhoeae. Statistical analysis of clinical manifestations showed that there was a significant association between the occurrence of N. gonorrhoeae and dysuria (P= 0.043), pelvic pain (P= 0.017), and fever (P = 0.045).Conclusion: Three promising markers were introduced for development of point-of-care testing approaches. Moreover, this study highlights a 4% prevalence of gonorrhea among women with genitourinary symptoms in Iran, which reminds the urgent need for routine surveillance and new policies in management of STIs, particularly gonorrhea.","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 4","pages":"850-859"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Machine Learning Analysis of Blood Glucose Regulation in Korean Male Workers with Type 2 Diabetes. 韩国2型糖尿病男性工人血糖调节的机器学习分析。

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18429

Haewon Byeon

引用次数: 0

The Role of TRPA1 as a Prognostic Marker in Colon Adenocarcinoma and Its Correlation with Mutations and Immunity. TRPA1作为结肠癌预后标志物的作用及其与突变和免疫的相关性

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18414

Xingxing Wu, Lifang Peng, Mingxu Zheng, Yuqing Mao, Heng Li, Shaopeng Sun

{"title":"The Role of TRPA1 as a Prognostic Marker in Colon Adenocarcinoma and Its Correlation with Mutations and Immunity.","authors":"Xingxing Wu, Lifang Peng, Mingxu Zheng, Yuqing Mao, Heng Li, Shaopeng Sun","doi":"10.18502/ijph.v54i4.18414","DOIUrl":"https://doi.org/10.18502/ijph.v54i4.18414","url":null,"abstract":"Background: This study aimed to investigate the prognostic value of TRP ion channel genes (TRPICGs) in colorectal adenocarcinoma (COAD) and explore its related mechanisms.Methods: The COAD dataset was downloaded from the Cancer Genome Atlas (TCGA) database. The differential expression genes (DEGs) were screened between COAD and normal samples. The differentially expressed TRPICGs (DE-TRPICGs) were obtained via intersection of DEGs and 28 TRPICGs. The Kaplan-Meier (K-M) survival curve was used to screen DE-TRPICGs with survival differences as prognostic markers. Afterward, the correlation of prognostic marker with clinical, immune cell, copy number variation were explored. Finally, immunohistochemistry (IHC) was used to verify the expression of prognostic marker.Results: Overall, 6003 DEGs were screened, and 6 DE-TRPICGs were obtained. Only TRPA1 was identified as prognostic biomarker. Survival and clinical correlation analyses implied that TRPA1 played an inhibitory role in colon adenocarcinoma pathogenesis and progression. Gene Set Enrichment Analysis (GSEA) indicated that TRPA1 was associated with cell cycle and immune-related pathways. Immune infiltration analysis showed that TRPA1 expression was significantly correlated with the infiltration of B cells, CD4+T cells, CD8+T cells, neutrophils and dendritic cells. Eventually, TRPA1 expression was down-regulated at the protein level in COAD samples, which presented consistent results with expression in the database.Conclusion: TRPA1 was identified in COAD as a prognostic marker associated with TRP ion channels, which provided a powerful reference value and a new direction for the diagnosis and treatment of COAD.","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 4","pages":"762-774"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045875/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Future of Nosocomial Infections. 医院感染的未来。

IF 1.4 4区医学

Iranian Journal of Public Health Pub Date : 2025-04-01 DOI: 10.18502/ijph.v54i4.18427

Hossein Moameri, Sahar Salehi, Ali Akbar Haghdoost

引用次数: 0