{"title":"Population Forecasting with Alzheimer's Disease in Iran Using a System Dynamic Model.","authors":"Vahidreza Borhaninejad, Milad Ahmadi Gohari, Yunes Jahani, Saber Amirzadeh Googhari, Nazanin Jannati, Moghaddameh Mirzaee","doi":"10.18502/ijph.v54i5.18641","DOIUrl":"10.18502/ijph.v54i5.18641","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of Alzheimer's disease in Iran, attributed to the demographic shift towards an aging population, holds considerable importance. We aimed to estimate the prevalence and number of Alzheimer's disease in Iran by 2029.</p><p><strong>Methods: </strong>Dynamic modeling techniques were employed to project the number of Alzheimer's disease (AD) among the elderly population in Iran by the year 2029. Two interconnected models were developed to facilitate this estimation. The initial model is a demographic model that captures the aging population's growth dynamics. The subsequent model, an AD evaluation model, that assess potential impacts on disease. This approach enables a comprehensive analysis of the factors influencing AD trends within the context of Iran's aging demographic.</p><p><strong>Results: </strong>The results show the number of individuals aged over 60 is expected to rise from approximately 9.1 million in 2020 to around 13.7 million in 2029. As the older adult population grows, the number of AD is also anticipated to increase. The number of Alzheimer's patients is predicted to grow from about 464,400 in 2020 to roughly 729,900 by 2029.</p><p><strong>Conclusion: </strong>Forecasting future trends in AD, especially in developing countries, is crucial for policymakers because of its growing impact on healthcare systems and economies globally. The findings of this study can aid in assessing the economic burdens associated with treating Alzheimer's patients, providing valuable insights for planning and resource allocation.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"1064-1073"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sustainable Development Goals and Health in Islamic Countries.","authors":"Gülay Ekinci, Mustafa Hakan Yılmaztürk","doi":"10.18502/ijph.v54i5.18639","DOIUrl":"10.18502/ijph.v54i5.18639","url":null,"abstract":"<p><strong>Background: </strong>We aimed to reveal the relationship between the Sustainable Development Goals (SDGs) and health indicators in Organization Islamic Countries (OIC).</p><p><strong>Methods: </strong>The panel data method was used in the analyses, health indicators as independent variables belonging to 16 Islamic countries with regular data from 2008-2021, and the SDG score as the dependent variable was considered.</p><p><strong>Results: </strong>A one-unit increase in maternal mortality reduced the SDG score by 0.0047 units, a one-unit increase in neonatal mortality reduced the SDG score by 0.27 units, besides these results no significant relationships were found between U5mort, NCD mort, TB, VAC variables, and SDG score (<i>P</i>>0.05). Granger causality analysis results showed different causal relationships and variance decomposition results show that the long-term explanatory effect of health indicators on the SDG score by approximately 23%.</p><p><strong>Conclusion: </strong>According to the empirical evidence obtained from the research, improvements in health indicators especially focused on mother and child health positively affect the SDG score in the countries examined.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"1044-1053"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Topology of Opsonization: A Cancer Geometry Hypothesis.","authors":"Babak Daneshfard, Mohammad Reza Sanaye","doi":"10.18502/ijph.v54i5.18649","DOIUrl":"10.18502/ijph.v54i5.18649","url":null,"abstract":"","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"1116-1117"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hangxing Sun, Dan Wu, Chao Lou, Jinhe Ying, Tao Zhang
{"title":"The Impact of Neuromuscular Stimulation on the Rehabilitation Outcomes of Patients Following Joint Replacement Surgery: A Systematic Review and Meta-Analysis.","authors":"Hangxing Sun, Dan Wu, Chao Lou, Jinhe Ying, Tao Zhang","doi":"10.18502/ijph.v54i5.18628","DOIUrl":"10.18502/ijph.v54i5.18628","url":null,"abstract":"<p><strong>Background: </strong>We aimed to comprehensively evaluate the impact of neuromuscular electrical stimulation (NMES) on rehabilitation outcomes in patients following joint replacement surgery.</p><p><strong>Methods: </strong>The systematic review and meta-analysis performed a computerized search of six databases-PubMed, Wiley Library, EMBASE, Web of Science, Cochrane Central, and PEDro-from 2009-2024, for relevant randomized controlled trials (RCTs). Two independent reviewers screened the literature, extracted data, and assessed the risk of bias according to predefined criteria. The primary outcome measures included range of Motion (ROM), pain scores, muscle strength, and functional recovery scores.</p><p><strong>Results: </strong>Ten RCTs involving 549 participants were included in the analysis, all of which met the inclusion criteria and had a moderate to low risk of bias. NMES significantly reduced pain scores in patients following joint replacement surgery (Standardized mean differences, with high heterogeneity (I<sup>2</sup> = 82%). NMES had no significant effect on flexion range of motion (I<sup>2</sup> = 33%) and a limited impact on extension range of motion (<i>P</i>=0.04). NMES positively affected quadriceps strength (I<sup>2</sup> = 95%). For the Timed Up and Go (TUG) test, NMES had a small positive effect (<i>P</i> < 0.01), but after standardizing TUG test scores based on baseline levels, NMES had a significant positive effect (<i>P</i> < 0.01). NMES had a significant positive effect on the stairs climb test (<i>P</i> < 0.01) and on function score (<i>P</i> = 0.01).</p><p><strong>Conclusion: </strong>NMES is an effective adjunctive therapy for improving joint range of motion, reducing pain, and enhancing functional recovery after joint replacement surgery, but further high-quality RCTs are needed to confirm these findings.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"928-938"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic Accuracy and Chromosomal Microarray and Karyotype Analysis with Different Clinical Biomarkers for Prenatal Diagnosis of Fetal Genetic Diseases.","authors":"Feifei Cai, Ru Shen, Haiou Wang, Yun Zheng, Weihang Zhang, Lixu Jin","doi":"10.18502/ijph.v54i5.18634","DOIUrl":"10.18502/ijph.v54i5.18634","url":null,"abstract":"<p><strong>Background: </strong>We compared the diagnostic accuracy and application value of chromosome microarray (CMA) technique and karyotype analysis for prenatal diagnosis of fetal genetic diseases using different clinical markers.</p><p><strong>Methods: </strong>This is a prospective clinical study involving 1587 pregnant women who underwent amniocentesis for prenatal diagnosis due to various abnormal clinical indications in China between May 2018 and Nov 2021. Both chromosome microarray and karyotype analysis were applied. Participants were categorized into six groups based on different indications for prenatal diagnosis. The detection rates of chromosome microarray and karyotype analysis were compared. The study utilized SPSS version 20 for data analysis, employing descriptive statistics for count data results and chi-square statistics for statistical associations between outcomes and predictors.</p><p><strong>Results: </strong>Chromosome microarray and karyotype analysis detected more abnormal chromosomes in the group with abnormal NIPT, with positive detection rates of 59.68% and the group in other situation with positive detection rates of 39.22%. Overall, 343 chromosome abnormalities were detected among participants. Overall, 101 cases chose induced labor, 240 cases gave birth, 1 newborn died after delivery, 1 case of twin chose selective reduction, another fetus gave birth, and 1 case lost to follow-up. The detection rate of chromosome abnormality in high-risk population was more than 1/5, highlighting the importance of reducing the incidence of birth defects through interventional prenatal diagnosis.</p><p><strong>Conclusion: </strong>Clinically, Down's screening, NIPT and prenatal ultrasound screening can be conducted initially, followed by karyotype analysis and CMA detection for those with abnormal findings.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"992-1002"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing Global Nursing Interventions in Reducing Hospital-Acquired Infections: A Meta-Analysis.","authors":"Fuping Ye, Lingfei Ma","doi":"10.18502/ijph.v54i5.18627","DOIUrl":"10.18502/ijph.v54i5.18627","url":null,"abstract":"<p><strong>Background: </strong>Hospital-acquired infections (HAIs) raise worldwide morbidity, death, and healthcare expenditures. Preventing and managing HAIs requires nursing interventions such hand hygiene, personal protective equipment (PPE) usage, environmental cleaning, and antimicrobial stewardship. This meta-analysis examined how nursing interventions reduced HAIs in different hospital settings.</p><p><strong>Methods: </strong>A complete PubMed, Scopus, and Web of Science search was undertaken for January 2000-December 2023 research. Studies on HAI-reducing nursing interventions were included. Study quality was evaluated using the Cochrane Risk of Bias Tool and Newcastle-Ottawa Scale. The random-effects model was used to construct pooled risk ratios (RRs) with 95% CIs in meta-analysis. We also performed subgroup, sensitivity, and publication bias analyses.</p><p><strong>Results: </strong>Fourteen trials with 2540 individuals were included. In the pooled study, nursing interventions significantly reduced HAI incidence (RR = 0.42, 95% CI: 0.35-0.50, <i>P</i> < 0.001). Subgroup analysis indicated that hand hygiene, PPE usage, environmental cleaning, and antimicrobial stewardship reduced HAIs. Sensitivity analysis verified these results' reliability. Egger's test showed no publication bias (<i>P</i> = 0.78). Over time, cumulative meta-analysis showed constant effect sizes.</p><p><strong>Conclusion: </strong>Nursing interventions significantly reduce HAIs. Hand hygiene, PPE, environmental cleaning, and antimicrobial stewardship are essential to infection control. Healthcare institutions should prioritise these actions and resolve compliance hurdles to enhance patient outcomes and minimise HAIs. Research is needed to explore innovative approaches and identify factors influencing compliance.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"915-927"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian Ricardo Zea Forero, Manuel Medina-Labrador, Magda Monroy Silva, Jose-Fernando Jimenez
{"title":"An Analysis of Hand Size and Grip Strength in a Working Population in Bogotá, Colombia.","authors":"Christian Ricardo Zea Forero, Manuel Medina-Labrador, Magda Monroy Silva, Jose-Fernando Jimenez","doi":"10.18502/ijph.v54i5.18635","DOIUrl":"10.18502/ijph.v54i5.18635","url":null,"abstract":"<p><strong>Background: </strong>Handgrip strength (HGS) has been extensively studied for its clinical and industrial significance, often linked to anthropometric measures like height, weight, and hand dimensions. In Colombia, research on these correlations exists but is fragmented and methodologically varied, limiting the ability to generalize findings. This lack of standardization highlights the need for a unified approach. This study aimed to address this gap by analyzing HGS in the Colombian context.</p><p><strong>Methods: </strong>Overall, 678 subjects (48.9% female and 51.1% male) were enrolled in 2022. They were aged between 18 and 63 yr old, apparently healthy, and were from Bogota, Colombia. It was measured using a Jamar dynamometer. To determine the seven variables of the hand, the posture recommended by the ASHT was followed.</p><p><strong>Results: </strong>Men had significantly higher HGS than women. The dominant hand represents 94.6% of females and 90.5% of males. However, dominance does not have a negative impact on gender when it is analyzed alone. The use of predictive models with cubic regressions permitted us to establish significant variables such as gender and hand width for the right hand and gender, age, hand thickness, and maximum palmar length for the left hand.</p><p><strong>Conclusion: </strong>The predictive models, the HGS relationship and the dimensions of the hand are evidenced, but in future studies it will be necessary to include the arm, forearm, and wrist sections to the methodology.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"1003-1013"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"NETosis in Autoimmunity: Cell-Mediated vs. Ab-Mediated.","authors":"Shabnam Babaei, Manouchehr Fadaee","doi":"10.18502/ijph.v54i5.18648","DOIUrl":"10.18502/ijph.v54i5.18648","url":null,"abstract":"","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"1113-1115"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alghafri Yasir Salim, Fariba Hossein Abadi, Nurul Fadhilah Abdullah, Al Kitani Mahfoodha, Norhazira Abdul Rahim
{"title":"The Prevalence and Predictive Risk Factors of Metabolic Syndrome Based on Health-Related Fitness Components in Omani Adolescents with Obesity.","authors":"Alghafri Yasir Salim, Fariba Hossein Abadi, Nurul Fadhilah Abdullah, Al Kitani Mahfoodha, Norhazira Abdul Rahim","doi":"10.18502/ijph.v54i5.18637","DOIUrl":"10.18502/ijph.v54i5.18637","url":null,"abstract":"<p><strong>Background: </strong>Significant linear trends indicate that rising adolescent obesity rates will increase the prevalence of metabolic syndrome (MetS) and associated health risks. We aimed to initially determine the prevalence of MetS among adolescents (aged 13-16 yr) with obesity in the South Al Batinah governorate in Oman (n=3404) based on data collected in 2024. Then to predict the risk factors of MetS criteria based on health-related fitness (HRF) components to identify the most significant risk factors among them (n= 512, with BMIile% ≥95%).</p><p><strong>Methods: </strong>A cross-sectional study was performed to determine the MetS prevalence. MetS criteria and HRF components were measured to examine key risk factors. Then, the predictive value of HRF variables for MetS incidence was assessed using multiple regression analysis.</p><p><strong>Results: </strong>The descriptive results from screening adolescents with obesity indicated that 10.7% of them exhibited MetS. A notable correlation between fast blood glucose (FBG) and cardiorespiratory fitness; CRF (r=0.28, <i>P</i>=0.001), waist circumference; WC (r=0.39, <i>P</i><0.0001), and BMI (r=0.46, <i>P</i><0.0001) were revealed. There was a robust correlation between blood pressure; BP and CRF (r=0.19, <i>P</i>=0.025), WC (r=0.24, <i>P</i>=0.007), and BMI (r=0.43, <i>P</i><0.0001). Multiple regression analysis showed a significant model for the high FBG prediction using the HRF variables, while the models predicted for BP were not significant.</p><p><strong>Conclusion: </strong>Significant correlation between HRF level and MetS criteria revealed that field-based tests HRF components, can be used to recognize MetS criteria among adolescents with obesity.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"1024-1033"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing Discharge Readiness and Factors in Peripherally Inserted Central Catheter Carriers with Malignant Tumors: A Meta-Analysis.","authors":"Wenyan Pan, Feng Zheng, Yangzhuo Shi","doi":"10.18502/ijph.v54i5.18630","DOIUrl":"10.18502/ijph.v54i5.18630","url":null,"abstract":"<p><strong>Background: </strong>The aim of this meta-analysis was to assess the readiness for discharge of patients with malignancy when carrying a peripherally inserted central catheter (PICC) as well as to explore the associated factors affecting readiness for discharge.</p><p><strong>Methods: </strong>PubMed, EMBASE, Web of Science, CNKI, WanFang and VIP databases from inception to Mar 2024 were systematically searched to collect relevant cross-sectional studies. Fixed-effects and random-effects models were used for effect size synthesis, and the stability of the results was assessed by heterogeneity testing, sensitivity analysis, and publication bias detection.</p><p><strong>Results: </strong>Eight cross-sectional studies comprising 748 participants were included, and the mean score for patients' readiness to discharge was 146.98 (95% CI: 127.17, 166.79) under a random-effects model, but the analysis showed a very high degree of heterogeneity (I<sup>2</sup>=100%, <i>P</i><0.01). In our in-depth analysis of factors influencing discharge readiness, we found that literacy level (OR=1.30, 95% CI: 1.07, 1.59) and income level (OR=1.77, 95% CI: 1.13, 2.78) were significantly associated with better readiness for discharge, and that age had a non-significant effect on readiness for discharge, with a combined effect size (OR = 1.03, 95% CI: 0.97, 1.08).</p><p><strong>Conclusion: </strong>Among patients with malignant tumours, self-efficacy, distance from home to the hospital, and income level have a significant impact on discharge readiness in their PICC carriers. Optimising discharge instructions and patient education strategies for these factors may improve patients' readiness for discharge, reduce the risk of PICC-related complications, and improve outcomes.</p>","PeriodicalId":14685,"journal":{"name":"Iranian Journal of Public Health","volume":"54 5","pages":"951-962"},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319451/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144789154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}