子痫前期：病因、病理生理学、危险因素、影响和预防：叙述性回顾。

IF 1.4 4区医学 Q3 Medicine

Iranian Journal of Public Health Pub Date : 2024-11-01 DOI:10.18502/ijph.v53i11.16941

Musliha Mustary, Ansariadi, Aminuddin Syam, Shanti Riskiyani, Kadek Ayu Erika, Apik Indarty Moedjiono, Mukhlis Lubis

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引用次数: 0

摘要

背景：先兆子痫（PE）导致全世界30%-40%的孕产妇和新生儿死亡。尽管不清楚确切的原因，但存在减轻不太严重的PE影响的策略。这篇综述探讨了PE的病因、病理生理学、危险因素、影响和预防。方法：在Scopus、PubMed、ProQuest、谷歌Scholar和Science Direct中搜索“先兆子痫和妊娠”和“预防”，获得2012-2022篇文章。结果：子痫前期表现为胎盘异常改变、免疫反应改变、滋养细胞凋亡和子宫灌注减少。危险因素包括高血压史、无产、年龄超过40岁、BMI超过35 kg/m2、家族史、羊膜妊娠、妊娠间隔长。这种情况有心血管疾病和新生儿发病率的风险，使卫生资源紧张。预防包括阿司匹林、维生素D、运动、叶酸、饮食、早期筛查和产前保健。结论：研究结果强调在产前护理中加强健康素养和子痫前期教育可以降低妇女PE的风险。为了提高孕妇的健康素养和降低PE风险，需要进一步的研究、新疗法和评估预防策略，并采用可获取的教育材料和多学科方法。

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Preeclampsia: Etiology, Pathophysiology, Risk Factors, Impact and Prevention: A Narrative Review.

Background: Preeclampsia (PE) caused 30%-40% of maternal and newborn deaths worldwide. Despite unclear exact cause, strategies exist to mitigate less severe PE effects. This review explores PE etiology, pathophysiology, risk factors, impact, and prevention.

Methods: Searching Scopus, PubMed, ProQuest, Google Scholar, and Science Direct for "preeclampsia and pregnancy" and "prevention" yielded 2012-2022 articles.

Results: Preeclampsia features abnormal placental changes, altered immunity response, trophoblast apoptosis, and reduced uterine perfusion. Risk factors include hypertension history, nulliparity, age over 40, BMI over 35 kg/m², family history, amniotic pregnancy, and long pregnancy interval. This condition risks cardiovascular and neonatal morbidity, straining health resources. Prevention involves aspirin, vitamin D, exercise, folic acid, diet, early screening, and antenatal care.

Conclusion: Findings emphasize enhancing health literacy and preeclampsia education in prenatal care to mitigate PE risk among women. Further research, novel therapies, and assessing prevention strategies with accessible educational materials and multidisciplinary approaches are warranted to enhance pregnant women's health literacy and decrease PE risk.

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来源期刊

Iranian Journal of Public Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

2.20

自引率

7.10%

发文量

审稿时长

2 months

期刊介绍： Iranian Journal of Public Health has been continuously published since 1971, as the only Journal in all health domains, with wide distribution (including WHO in Geneva and Cairo) in two languages (English and Persian). From 2001 issue, the Journal is published only in English language. During the last 41 years more than 2000 scientific research papers, results of health activities, surveys and services, have been published in this Journal. To meet the increasing demand of respected researchers, as of January 2012, the Journal is published monthly. I wish this will assist to promote the level of global knowledge. The main topics that the Journal would welcome are: Bioethics, Disaster and Health, Entomology, Epidemiology, Health and Environment, Health Economics, Health Services, Immunology, Medical Genetics, Mental Health, Microbiology, Nutrition and Food Safety, Occupational Health, Oral Health. We would be very delighted to receive your Original papers, Review Articles, Short communications, Case reports and Scientific Letters to the Editor on the above mentioned research areas.