Iranian Red Crescent Medical Journal最新文献

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Investigating the Resilience of Bandar Abbas Neighborhoods against Disaster 调查阿巴斯港居民区的抗灾能力
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2023-06-24 DOI: 10.32592/ircmj.2023.25.8.2765
{"title":"Investigating the Resilience of Bandar Abbas Neighborhoods against Disaster","authors":"","doi":"10.32592/ircmj.2023.25.8.2765","DOIUrl":"https://doi.org/10.32592/ircmj.2023.25.8.2765","url":null,"abstract":"Background: Urban planning and urban planning activities have increased the pressure on nature and weakened its resilience, often bringing negative and even irreparable consequences. Objectives: One of the most important issues in urban management in recent years is the emergence of resilient cities. Hormozgan is one of the most important provinces of the country, and Bandar Abbas, in the center of this province, is considered one of the major coastal cities of Iran from a national point of view. Methods: To identify and examine the resilience of Bandar Abbas against environmental crises, based on which an information base was created, the place and spatial information of this database was prepared in 5 criteria and 29 sub-criteria. They include 1. socio-economic criteria, 2. structural criteria, 3. access criteria, 4. physical criteria, and 5. Ecological criteria. In the next step, to weigh and value the research criteria and sub-criteria in the resilience model of Bandar Abbas, the network analysis method (ANP) was used. In this model, the first 50 questionnaires were prepared by the Delphi method and distributed among experts in the field of environment and disaster management. Results: The findings of this study indicated that the weight and value of ecological, socio-economic, physical, accessibility, and physical-structural criteria in resilience were 0.256, 0.236, 0.194, 0.171, and 0.141, respectively. Among the ecological criteria, the sub-criterion of distance from polluted points, the socio-economic criterion, the sub-criterion of access to medical-health centers, the sub-criterion of access to medical-health centers, among the physical-structural criteria, flood risk sub-criterion, and functional zone sub-criterion, and among access criteria, the sub-criterion of access to the fire station obtained the highest values in resilience. Conclusion: Environmental crises, such as earthquakes, floods, accidents, air pollution, and storms, have resulted in the environmental vulnerability of the city and posed serious threats to the security of Bandar Abbas. A thorough understanding of the vulnerability of Bandar Abbas against urban environmental crises will enable policymakers to propose management solutions to reduce vulnerability and risk and increase resilience. Consequently, the main goal of this study was to evaluate the resilience of Bandar Abbas against environmental crises. The results of this study can be of great help in the decision-making of city managers and the lives of city residents.","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139368726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Lower Urinary Symptoms Following Vaginal Reconstructive Surgery for Prolapse and Urinary Incontinence 针对脱垂和尿失禁的阴道重建手术后的下尿路症状评估
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2023-06-18 DOI: 10.32592/ircmj.2023.25.9.2793
{"title":"Evaluation of Lower Urinary Symptoms Following Vaginal Reconstructive Surgery for Prolapse and Urinary Incontinence","authors":"","doi":"10.32592/ircmj.2023.25.9.2793","DOIUrl":"https://doi.org/10.32592/ircmj.2023.25.9.2793","url":null,"abstract":"Background: Urinary incontinence (UI) may be associated with symptoms of overactive bladder (OAB) that may persist after anti-incontinence surgery. Objectives: The present study was performed to evaluate the effect of prolapse and anti-incontinence reconstructive surgery in women who had the symptoms of OAB and UI at the same time. Methods: This descriptive cross-sectional study was performed on 56 women with OAB symptoms and stress UI (SUI)/urgency UI (UUI) with or without prolapse who were candidates for restorative and anti-incontinence surgery. At baseline, urinary symptoms, including urinary frequency, nocturia, SUI, and UUI, were recorded. Patients who finally underwent vaginal reconstructive surgery with anti-incontinence surgery were assessed for urinary symptoms six months after the operation. Results: A total of 28 patients underwent transobturator tape (TOT) surgery, of whom 23 patients were subjected to other anti-incontinence surgeries and 5 patients underwent restorative surgeries. There was no significant difference between the two groups (TOT and others) in terms of age, body mass index, number of deliveries, history of medical problems, and history of surgery or cesarean section. The urinary frequency and nocturia before surgery were observed in 46 (82%) and 20 (36%) patients, respectively, which were not significantly different between the two groups. Before the study, occult UI was observed in 2 patients (4%), UUI in 3 patients (5%), SUI in 18 patients (32%), and mixed UI in 33 patients (59%). Nocturia was completely improved in all 20 patients. Urinary frequency was partially or completely improved in 41 patients (89%), which was not significantly different between the two groups (P=0.051). Overall, 53 patients (95%) had partial or complete improvement in UI, which was not significantly different between the two groups (P=0.058). Both patients with occult UI and all three patients with UUI were completely improved. Sixteen out of 18 patients (89%) with SUI were completely improved and the other 2 patients were partially improved. Thirty patients (91%) with mixed UI had a complete or partial recovery that was not significantly different between the two groups (P=0.137). Conclusion: The findings of the present study showed that six months after anti-incontinence or reconstructive surgery, nocturia in all patients and urinary frequency in 89% of patients improved partially or completely. Various forms of UI partially or completely improved in 95% of patients, as well.","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139369505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Cancer Stem Cell on Cardio-toxicity: Molecular Mechanism and Future Approach 癌症干细胞对心脏毒性的影响:分子机制与未来方法
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2023-06-14 DOI: 10.32592/ircmj.2023.25.8.2633
{"title":"Effect of Cancer Stem Cell on Cardio-toxicity: Molecular Mechanism and Future Approach","authors":"","doi":"10.32592/ircmj.2023.25.8.2633","DOIUrl":"https://doi.org/10.32592/ircmj.2023.25.8.2633","url":null,"abstract":"Background: A rise in the cancer rate causes an increase in the occurrence of cardio-toxic complications while using chemotherapy drugs. Cancer stem cells (CSCs) are cell masses resistant to cancer treatment which escape from cell death by changing signaling pathways. Therefore, increasing the dosage of chemotherapy drugs increases the damage to the heart tissue and the consequences of cardio-toxicity. Investigating the signaling pathways responsible for the survival of CSCs through changing the amount of reactive oxygen species (ROS), inflammation, and apoptosis, and the effect of these factors on cardiomyocytes at the molecular level can provide a more detailed view of how the cardiotoxicity process works. Among the important signaling pathways involved in the cardiotoxicity process, through the three processes of increasing oxidative stress, inflammation, and apoptosis, we can mention Notch, pI3K/AKT, wnt signaling pathways, and NF-kB. This approach can suggest therapeutic methods capable of destroying CSCs with less cardiotoxicity effects. Conclusion: Finally, as a hypothesis, it can be said that effective factors on the survival of CSCs can influence the cardio-toxicity by impacting ROS, inflammation, and apoptosis process.","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139369995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Self-perineal Care Education using a Mobile Application on Knowledge and Practice of Perineal Care among Primigravida Mothers: A Quasi-Experimental Study 使用移动应用程序进行会阴自我护理教育对初产妇会阴护理知识和实践的影响:准实验研究
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2023-06-08 DOI: 10.32592/ircmj.2023.25.8.2545
{"title":"Effects of Self-perineal Care Education using a Mobile Application on Knowledge and Practice of Perineal Care among Primigravida Mothers: A Quasi-Experimental Study","authors":"","doi":"10.32592/ircmj.2023.25.8.2545","DOIUrl":"https://doi.org/10.32592/ircmj.2023.25.8.2545","url":null,"abstract":"Background: Poor self-perineal care (SPC) by new mothers due to inadequate knowledge can result in perineal pain and poor wound healing outcome. Objectives: This study aimed to evaluate the effectiveness of self-perineal care education on knowledge and practice among primigravida mothers in Malaysia. Methods: This quasi-experimental study was conducted in two public tertiary care hospitals from September 2019 to March 2020. In total, 125 mothers were recruited using consecutive sampling procedures from two tertiary care hospitals. The intervention group consisted of 62 mothers who received SPC education supplemented by the mobile app, while the other 63 mothers in the control group received only routine hospital care. The knowledge of mothers regarding SPC was assessed at 32 to 33 weeks of gestation and then at 4 h post-delivery. The mothers of both groups reported their perineal care practices on Day 1, Day 3, Day 5, and Day 7 post-childbirth using the SPC education mobile app. Results: There was no significant difference in the SPC knowledge scores between the two groups at baseline (P=0.155). Post-analysis showed a significant increase in the SPC knowledge score in the intervention group (P<0.001) but not in the control group (P=0.133). At all-time points, the mothers in the intervention group performed better SPC practice than those in the control group (P<0.001). There were significant associations between changes in knowledge and practice on all four days (P<0.001). Conclusion: The increased knowledge of SPC was significantly associated with improved SPC practice among the primipara mothers postnatally.","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139370585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Critical Alert for Otolaryngologists: Earache May be the Early Signs of COVID-19 耳鼻喉科医生的重要警示:耳痛可能是 COVID-19 的早期征兆
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2020-05-31 DOI: 10.5812/ircmj.103836
S. Miri, M. Ajalloueyan
{"title":"Critical Alert for Otolaryngologists: Earache May be the Early Signs of COVID-19","authors":"S. Miri, M. Ajalloueyan","doi":"10.5812/ircmj.103836","DOIUrl":"https://doi.org/10.5812/ircmj.103836","url":null,"abstract":"Introduction: The pandemic coronavirus disease 2019 or COVID-19 is infecting as fast as possible in more than 200 countries and creating the most horrible domino-like demolition ever seen. From its beginning in Wuhan, China, the SARS-CoV-2 infected the similar groups of 100,000 patients in 67, 11, 4, and 2 days. Healthcare workers are in the frontline of attacking by SARS-CoV-2, especially those who are in close contact with upper respiratory mucosa like otolaryngologists. Objectives: To describe ear pain as one of the first clinical manifestations of COVID-19, we present two cases of a family (a mother and her daughter) with a positive RT-PCR test for COVID-19 who presented earache as their first symptoms. Case Presentation: The first case was a 32 years old female patient (stewardess of an international airline, Tehran, Iran) was labeled as at risk due to her air flight to China in Dec 2019. She was first admitted for moderate ear pain in her left ear with mild itching of the external ear to an otolaryngology outpatient clinic by a general practitioner. After 7 days, her test for RT-PCR against COVID-19 was positive. No lung involvement was reported by high-resolution computed tomography (HRCT) of the thorax. Another case was her mother who were in close contact with each other and experienced severe ear pain after 7 days. She acquired mild COVID-19 symptoms with anosmia was a positive test result for COVID-19. Conclusions: The earache must be considered as their first clinical symptoms during the early phase of the coronavirus outbreak. It seems that local and international scientific groups of otolaryngologists must prepare their national guidelines to protect their practitioners against COVID-19 based on practical strategies. Using personal protective equipment is of utmost importance in reducing the risk of nosocomial infection among otolaryngologists.","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141201796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Efficacy and safety of aluminum chloride in controlling external hemorrhage: an animal model study. 氯化铝控制外出血的有效性和安全性:动物模型研究。
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2015-03-20 eCollection Date: 2015-03-01 DOI: 10.5812/ircmj.19714
Saeed Nouri, Mohammad Reza Sharif, Yunes Panahi, Mostafa Ghanei, Bardia Jamali
{"title":"Efficacy and safety of aluminum chloride in controlling external hemorrhage: an animal model study.","authors":"Saeed Nouri,&nbsp;Mohammad Reza Sharif,&nbsp;Yunes Panahi,&nbsp;Mostafa Ghanei,&nbsp;Bardia Jamali","doi":"10.5812/ircmj.19714","DOIUrl":"https://doi.org/10.5812/ircmj.19714","url":null,"abstract":"<p><strong>Background: </strong>Despite all the progress in surgical science, bleeding caused by traffic accidents is still one of the challenges surgeons face in saving patients' lives. Therefore, introducing an effective method to control external bleeding is an important research priority.</p><p><strong>Objectives: </strong>This study aimed to compare the hemostatic effect of aluminum chloride versus simple suturing in controlling external bleeding.</p><p><strong>Materials and methods: </strong>This experimental study was conducted in Kashan, Iran. In this study, 60 male Wistar rats were randomly allocated into six groups. An incision, two centimeters (cm) long and half a cm deep, was made on each rat's shaved back skin and the hemostatic time was measured once using aluminum chloride with different concentrations (5%, 10%, 15%, 25%, and 50%) and then using the control method (controlling hemorrhage by simple suturing). The skin tissue was assessed for pathological changes.</p><p><strong>Results: </strong>The hemostatic time of aluminum chloride 50%, 25%, 15%, 10% and 5% were 8.20 ± 0.919, 14.10 ± 1.37, 21.20 ± 1.31, 30.80 ± 1.68 and 42.00 ± 4.19 seconds, respectively. Also, the mean hemostasis time in the control group (suture) was 84.00 ± 4.05 seconds. The hemostatic times of different concentrations of aluminum chloride were significantly less than that of the control group. There was a statistically significant difference between every two hemostatic time. The pathologic examination showed the highest frequency of low-grade inflammation based on the defined pathological grading.</p><p><strong>Conclusions: </strong>The aluminum chloride method needs less time to control external hemorrhage compared to the control method (controlling external hemorrhage by simple suturing). Aluminum chloride is an effective agent in controlling external hemorrhage in an animal model.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2015-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/64/ircmj-17-03-19714.PMC4417476.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33295868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Individual patient data meta-analysis of the smoking prevalence in mazandaran province of iran. 伊朗马赞达兰省吸烟率的个体患者数据荟萃分析。
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2015-02-21 eCollection Date: 2015-02-01 DOI: 10.5812/ircmj.10294
Mahmood Moosazadeh, Mohammadreza Amiresmaili, Mahdi Afshari
{"title":"Individual patient data meta-analysis of the smoking prevalence in mazandaran province of iran.","authors":"Mahmood Moosazadeh,&nbsp;Mohammadreza Amiresmaili,&nbsp;Mahdi Afshari","doi":"10.5812/ircmj.10294","DOIUrl":"https://doi.org/10.5812/ircmj.10294","url":null,"abstract":"<p><strong>Background: </strong>Smoking is regarded as one of the main risk factors and additive to the global burden of diseases in the World.</p><p><strong>Objectives: </strong>This individual patient data (IPD) meta-analysis aimed to estimate the smoking prevalence in Mazandaran province of Iran.</p><p><strong>Materials and methods: </strong>This study was an IPD meta-analysis. The study data were part of the STEPS Study in Mazandaran province (northern Iran), conducted annually from 2005 to 2009. Sample size was 7759 subjects. Sampling method was census. Data entry was in Epi6 software and the analyses were with stata 11 software.</p><p><strong>Results: </strong>Mean (standard error) age of starting to smoke was 20.21 (0.6) years and females had started smoking 4 years later (P = 0.01). During the study, men smoked cigarettes more than women (total prevalence: 23.2%; 95% CI: 22.5-23.9 vs. 0.9%; 95% CI: 0.7-1.1 respectively). The pooled prevalence of the current smoking was estimated about 12.08 % (95% CI: 11.40-12.81).</p><p><strong>Conclusions: </strong>Present study showed that the prevalence of Smoking in men is very high in this region of Iran. Therefore to prevent the problem it is necessary that educational and research centres and health providers make suitable policies and strategies .</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/19/56/ircmj-17-02-10294.PMC4353219.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33147562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Randomized, clinical trial on diathermy and scalpel incisions in elective general surgery. 在择期普外科手术中使用电热疗法和手术刀切口的随机临床试验。
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2015-02-21 eCollection Date: 2015-02-01 DOI: 10.5812/ircmj.14078
Altaf Ahmed Talpur, Abdul Basir Khaskheli, Nandlal Kella, Akmal Jamal
{"title":"Randomized, clinical trial on diathermy and scalpel incisions in elective general surgery.","authors":"Altaf Ahmed Talpur, Abdul Basir Khaskheli, Nandlal Kella, Akmal Jamal","doi":"10.5812/ircmj.14078","DOIUrl":"10.5812/ircmj.14078","url":null,"abstract":"<p><strong>Background: </strong>Since a long time skin incisions have routinely been made with scalpels. Now a day there is a shift in trend from this method to electrosurgical skin incisions. However, fear of bad scars and improper wound healing has prevented its wide spread use. This Study aimed to compare both methods of skin incisions for different variables.</p><p><strong>Objectives: </strong>The aim of this study was to examine incisional time, blood loss during incision and postoperative wound complications and pain with both methods of skin incision.</p><p><strong>Patients and methods: </strong>A prospective, comparative and randomized study was conducted at different hospitals of Hyderabad and Nawabshah, Pakistan from 1(st) of December 2009 to 30(th) of November 2011. The study included patients of either sex above the age of five years with general surgical pathology who were to undergo surgery. these candidates were randomly put into two groups. In Group A patients incision was made with a scalpel and in group B with diathermy. Data was analyzed for age, sex, comorbid illness, incisional time, blood loss during incision making and postoperative pain and wound complications.</p><p><strong>Results: </strong>A total of 283 patients completed the follow-up and were included in the final analysis. Group A comprised of 143 (50.53%) patients; 83 (58%) males and 60 (42%) females with a mean age of 36.03 years. Amongst the 140 patients of group B, there were 85 (60.7%) males and 55 (39.3%) females with a mean age of 36.52 years. Twenty-five (17.48%) patients of group A and 27 (19.28%) of group B had comorbid illnesses. Mean incision time was 8.9025-sec/cm(2) for group A and 7.3057 sec/cm(2) for group B patients. Mean blood loss during incision making was 1.8262 mL/cm(2) and 1.1346 mL/cm(2) for group A and B patients, respectively. Pain was 5.2957 for group A patients on day one and 3.1181 for group B patients. Pain score was 2.1049 and 1.6206 on day two and 0.8191 and 0.7192 on day five, for group A and B patients, respectively. Postoperative wound complications were noticed in 26 (18.18%) patients of group A and 22 (15.71%) patients of group B.</p><p><strong>Conclusions: </strong>Diathermy incision is a safe and expedient technique. It takes less time than scalpel incision and loss of blood is also lower during incision. Diathermy is associated with lesser post-operative pain and complications than the scalpel incision. Diathermy should be method of choice in general elective surgery.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f0/94/ircmj-17-02-14078.PMC4376978.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33182958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fecal Calprotectin is an Accurate Tool and Correlated to Seo Index in Prediction of Relapse in Iranian Patients With Ulcerative Colitis. 粪钙保护蛋白是预测伊朗溃疡性结肠炎患者复发的准确工具并与Seo指数相关。
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2015-02-21 eCollection Date: 2015-02-01 DOI: 10.5812/ircmj.22796
Seyed Vahid Hosseini, Peyman Jafari, Seyed Alireza Taghavi, Ali Reza Safarpour, Abbas Rezaianzadeh, Maryam Moini, Manoosh Mehrabi
{"title":"Fecal Calprotectin is an Accurate Tool and Correlated to Seo Index in Prediction of Relapse in Iranian Patients With Ulcerative Colitis.","authors":"Seyed Vahid Hosseini,&nbsp;Peyman Jafari,&nbsp;Seyed Alireza Taghavi,&nbsp;Ali Reza Safarpour,&nbsp;Abbas Rezaianzadeh,&nbsp;Maryam Moini,&nbsp;Manoosh Mehrabi","doi":"10.5812/ircmj.22796","DOIUrl":"https://doi.org/10.5812/ircmj.22796","url":null,"abstract":"<p><strong>Background: </strong>The natural clinical course of Ulcerative Colitis (UC) is characterized by episodes of relapse and remission. Fecal Calprotectin (FC) is a relatively new marker of intestinal inflammation and is an available, non-expensive tool for predicting relapse of quiescent UC. The Seo colitis activity index is a clinical index for assessment of the severity of UC.</p><p><strong>Objectives: </strong>The present study aimed to evaluate the accuracy of FC and the Seo colitis activity index and their correlation in prediction of UC exacerbation.</p><p><strong>Patients and methods: </strong>In this prospective cohort study, 157 patients with clinical and endoscopic diagnosis of UC selected randomly from 1273 registered patients in Fars province's IBD registry center in Shiraz, Iran, were followed from October 2012 to October 2013 for 12 months or shorter, if they had a relapse. Two patients left the study before completion and one patient had relapse because of discontinuation of drugs. The participants' clinical and serum factors were evaluated every three months. Furthermore, stool samples were collected at the beginning of study and every three months and FC concentration (commercially available enzyme linked immunoassay) and the Seo Index were assessed. Then univariate analysis, multiple variable logistic regression, Receiver Operating Characteristics (ROC) curve analysis, and Pearson's correlation test (r) were used for statistical analysis of data.</p><p><strong>Results: </strong>According to the results, 74 patients (48.1%) relapsed during the follow-up (33 men and 41 women). Mean ± SD of FC was 862.82 ± 655.97 μg/g and 163.19 ± 215.85 μg/g in relapsing and non-relapsing patients, respectively (P < 0.001). Multiple logistic regression analysis revealed that age, number of previous relapses, FC and the Seo index were significant predictors of relapse. ROC curve analysis of FC level and Seo activity index for prediction of relapse demonstrated area under the curve of 0.882 (P < 0.001) and 0.92 1(P < 0.001), respectively. Besides, FC level of 341 μg/g was identified as the cut-off point with 11.2% and 79.7% relapse rate below and above this point, respectively. Additionally, Pearson correlation coefficient (r) between FC and the Seo index was significant in prediction of relapse (r = 0.63, P < 0.001).</p><p><strong>Conclusions: </strong>As a simple and noninvasive marker, FC is highly accurate and significantly correlated to the Seo activity index in prediction of relapse in the course of quiescent UC in Iranian patients.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d4/df/ircmj-17-02-22796.PMC4353186.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33147024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Pregnancy experiences of first-time fathers in iran: a qualitative interview study. 伊朗初为人父的怀孕经历:一项质性访谈研究。
IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2015-02-21 eCollection Date: 2015-02-01 DOI: 10.5812/ircmj.12271
Shahnaz Golian Tehrani, Shahin Bazzazian, Nahid Dehghan Nayeri
{"title":"Pregnancy experiences of first-time fathers in iran: a qualitative interview study.","authors":"Shahnaz Golian Tehrani,&nbsp;Shahin Bazzazian,&nbsp;Nahid Dehghan Nayeri","doi":"10.5812/ircmj.12271","DOIUrl":"https://doi.org/10.5812/ircmj.12271","url":null,"abstract":"<p><strong>Background: </strong>Fatherhood, similarly to motherhood, is an important role and responsibility. For accepting this role, one needs to be well-prepared. Awareness of father's experiences of pregnancy can help us to develop plans for the promotion of the role of fatherhood.</p><p><strong>Objectives: </strong>The purpose of this study was to explore how first time fathers describe their experiences of pregnancy.</p><p><strong>Patients and methods: </strong>The data in this qualitative study were collected by individual open-ended interviews in five public health prenatal care clinics in Tehran, Iran, during 2010 ‒ 2011. Participants were 26 Iranian and Moslem first-time fathers living in Tehran, whose partner was in the 32th to 40th week of her normal pregnancy. Qualitative content text analysis was used for analyzing interviews.</p><p><strong>Results: </strong>Through analysis of fathers' experiences of their wives' pregnancy, four categories, as well as associated subcategories, emerged. The categories include: \"Emotional responses to pregnancy, Feeling of change, Accepting the reality and satisfaction, Developing identity as a father.\" These categories describe the phenomenon of \"Transition to fatherhood\".</p><p><strong>Conclusions: </strong>Transition to fatherhood extends beyond only moderate mental and social changes, and may be influenced by cultural background and beliefs. Therefore, caregivers should be aware of fathers' changes and needs during pregnancy, and support them while taking into consideration their culture and beliefs.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5812/ircmj.12271","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33188263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 28
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