{"title":"Effect of Cinnamomum zeylanicumon on Spermatogenesis.","authors":"Arash Khaki","doi":"10.5812/ircmj.18668","DOIUrl":"https://doi.org/10.5812/ircmj.18668","url":null,"abstract":"<p><strong>Background: </strong>In modern countries today, herbal medicines are known to help in the treatment of various diseases, as rich sources of antioxidants and minerals.</p><p><strong>Objectives: </strong>To study the effect of Cinnamomum zeylanicum (C. zeylanicum) on spermatogenesis in rats.</p><p><strong>Materials and methods: </strong>In this experimental study, Wistar male rats (n = 20) were divided into two groups, a control group (n = 10) and a Cinnamomum zeylanicum group (n = 10). The subjects in the cinnamon group received 75 mg/kg/day cinnamon by gavage for 28 days, while the controls received an equal volume of distilled water daily. Animals were kept in standardized conditions. On day 28, a 5 mL blood sample from each rat was taken from tail area to measure testosterone, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), and malondialdehyde (MDA) levels. Testes were collected and were then prepared for sperm analysis by the WHO method.</p><p><strong>Results: </strong>Sperm quality parameters, total serum testosterone, SOD, CAT, and GPX levels were significantly increased in the cinnamon group in comparison to controls (P < 0.05). Also, rats in the cinnamon group showed a significant decrease in the level of plasma MDA (P < 0.05) in comparison to controls. There were no significant differences between the groups in testis weight (P > 0.05).</p><p><strong>Conclusions: </strong>The administration of 75 mg/kg/day cinnamon significantly increased the sperm population, motility and viability, which supports the theory that in mammalians, cinnamon has a beneficial effect on spermatogenesis.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e18668"},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5812/ircmj.18668","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33061955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashiru Hamza Mohammad, Nabilla Al Sadat, Siew Yim Loh, Karuthan Chinna
{"title":"Validity and reliability of the hausa version of multidimensional scale of perceived social support index.","authors":"Ashiru Hamza Mohammad, Nabilla Al Sadat, Siew Yim Loh, Karuthan Chinna","doi":"10.5812/ircmj.18776","DOIUrl":"10.5812/ircmj.18776","url":null,"abstract":"<p><strong>Background: </strong>Social support has been identified as one of the key factors for enhancing the quality of life after stroke. However, a scientific tool that is valid for evaluating social support among stroke survivors in Nigeria has not been developed so far.</p><p><strong>Objectives: </strong>The objective of this study was to examine the psychometric properties of the Hausa translated versions of the Multidimensional Scale of Perceived Social Support (MSPSS) and to validate it for future use in clinical research in Nigeria.</p><p><strong>Patients and methods: </strong>This cross-sectional study was conducted on a sample of 140 adult stroke survivors attending rehabilitation services at stroke referral centers in Kano, Nigeria. The psychometric analysis of the Hausa-MSPSS involved face, content, criterion and construct validity tests, as well as internal and test-retest reliability. Confirmatory factor analysis was performed to assess validity of the three-factor (Family, Friends and Significant others) model for the Hausa-MSPSS.</p><p><strong>Results: </strong>Based on expert panel, clinicians' review and patients' feedback, the 12 item Hausa-MSPSS had sufficient face, content and criterion validity. In reliability analysis, the Cronbach's alpha was 0.781. In test-retest reliability analysis, the minimum kappa value was 0.673. In Confirmatory factor analysis, the three-factor model was not acceptable. An alternative two-factor model with Family and Friends, as the two domain was found to be acceptable (Chi-square/df < 3, TLI, CFI > 0.9, RMSEA < 0.08). The average variances extracted for the two constructs were 0.5 and 0.7, respectively. The R-squared value between the two constructs was 0.397. Cross validity tested using 1000 bootstrap resamples gave satisfactory results (P = 0.079).</p><p><strong>Conclusions: </strong>The 11 item Hausa-MSPSS index is valid for the assessment of perceived social support among stroke survivors in Nigeria.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e18776"},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c6/33/ircmj-17-02-18776.PMC4376991.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33061956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Casein phosphopeptide-amorphous calcium phosphate and shear bond strength of adhesives to primary teeth enamel.","authors":"Elham Farokh Gisovar, Nassim Hedayati, Niloofar Shadman, Leila Shafiee","doi":"10.5812/ircmj.11167","DOIUrl":"https://doi.org/10.5812/ircmj.11167","url":null,"abstract":"<p><strong>Background: </strong>CPP-ACP (Phosphopeptide-Amorphous Calcium Phosphate) has an important role in caries prevention in pediatric patients. This study was done, because of the great use of CPP-ACP and the need for restoration for teeth treated with CPP-ACP as well as the importance of shear bond strength of adhesives in the success of restorations.</p><p><strong>Objectives: </strong>This study aimed to evaluate the effect of casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) on shear bond strength of dental adhesives to enamel of primary teeth molars.</p><p><strong>Materials and methods: </strong>This in vitro study was conducted on 180 extracted primary molars. They were randomly divided into 6 groups and each group was divided into 2 subgroups (treated with CPP-ACP and untreated). In subgroups with CPP-ACP, enamel was treated with CPP-ACP paste 1 h/d for 5 days. Types of adhesives that were evaluated in this study were Tetric N-Bond, AdheSE, AdheSE One F, single Bond 2, SE Bond, and Adper Prompt L-Pop. Shear bond strength was tested with a universal testing machine and mode of failure was evaluated under stereomicroscope. Data were analyzed by T test, 2-way analysis of variance (ANOVA), Tukey and Fisher exact test using SPSS18. P < 0.05 was considered as significance level.</p><p><strong>Results: </strong>Shear bond strengths of different adhesive systems to enamel of primary teeth treated and untreated with CPP-ACP showed no significant difference (P > 0.05). Mode of failure in all groups regardless of CPP-ACP administration was mainly adhesive type. Our results indicated that CPP-ACP did not affect shear bond strength of studied adhesives to primary teeth enamel.</p><p><strong>Conclusions: </strong>To have a successful and durable composite restoration, having a high strength bonding is essential. Considering the wide use of CPP-ACP in preventing tooth decay and the role of adhesive shear bond strength (SBS) in success of composite restoration, we conducted the present study to evaluate the effect of CPP-ACP on the SBS of adhesives to primary teeth enamel.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e11167"},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a1/d4/ircmj-17-02-11167.PMC4353185.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33147563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How does a group of Iranian youth conceptualize their risky sexual experiences?","authors":"Mahnaz Noroozi, Effat-Al-Sadat Merghati Khoei, Fariba Taleghani, Mahgol Tavakoli, Ali Gholami","doi":"10.5812/ircmj.18301","DOIUrl":"https://doi.org/10.5812/ircmj.18301","url":null,"abstract":"<p><strong>Background: </strong>There are restrictions as well as lawful and religious prohibition for sexual relationships in Iranian society.</p><p><strong>Objectives: </strong>This study explores the varied experiential reality of Iranian youth and their risky sexual experiences.</p><p><strong>Patients and methods: </strong>Data collection is based on semi-structured interviews with 30 single young men and women. Observation of interactions of youth in different settings has been another source of information. Interviews were microscopically content analyzed.</p><p><strong>Results: </strong>The accounts of risky sexual experiences included gendered behavioral, cultural, and cognitive factors. In the re-contextualizing process, these accounts were categorized by two main themes: \"gendered sexual script\" and \"cultural scenarios of interpersonal interactions\". The notion of \"male power\" was evident in the responses provided by the participants. Women seldom asked for condom use due to limited knowledge about STIs-HIV/AIDS and unpleasant experiences with condoms. Men had limited knowledge about various sexual modes of HIV and STIs transmission and did not use condoms consistently because they had not seen themselves at risk of STIs or HIV as well as their belief about the decrease of sexual pleasure.</p><p><strong>Conclusions: </strong>Rising youth awareness, creating a positive attitude, and appropriate knowledge about safe sex practices are seminal. It is also vital to ensure access to gender specific sexual and reproductive health services for youths, empower women, and strengthen their sexual assertiveness as well as the elimination of all forms of gender-based inequalities.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e18301"},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4a/a9/ircmj-17-02-18301.PMC4376993.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33188266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical determinants of left ventricular ejection fraction deterioration in patients suffered from complete left bundle branch block.","authors":"Mohammad Hashemi Jazi, Peyman Nilforoush, Mojgan Gharipour, Azadeh Batvandi, Robabeh Mohammadi, Roya Najafi","doi":"10.5812/ircmj.16570","DOIUrl":"https://doi.org/10.5812/ircmj.16570","url":null,"abstract":"<p><strong>Background: </strong>Recently, the deleterious effects of left bundle branch block (LBBB) on left ventricular systolic function have been taken into consideration.</p><p><strong>Objectives: </strong>The present study aimed to identify underlying factors that predict left ventricular ejection fraction (LVEF) deterioration in patients suffered from complete LBBB.</p><p><strong>Patients and methods: </strong>In a retrospective case-control study, the data of 220 consecutive patients diagnosed with LBBB on their electrocardiograms were assessed. They were referred to Isfahan Heart Center in Isfahan Province, Iran in 2013. LVEF deterioration was defined as a decrease in LVEF at least 10% between the baseline and follow-up echocardiography study. Thus, achieving the LVEF values ≤ 40% in patients with an initial EF of > 50% was considered LVEF deterioration.</p><p><strong>Results: </strong>Among 220 patients, 40% of LBBB patients suffered LVEF deterioration within 3 months of initial assessment. The group with LVEF deterioration had higher male to female ratio, had higher NYHA score, and suffered more from systolic hypertension than another group. Those with coronary artery disease (CAD) had also significantly lower LVEF than non-CAD ones. Adverse associations were revealed between systolic blood pressure and LVEF measurement (r = -0.193, P = 0.006) as well as between NYHA score and LVEF (r = -0.215, P = 0.002). A multivariable logistic regression model showed that among baseline variables, male gender (OR = 3.218, P < 0.001), history of systolic hypertension (OR = 2.012, P = 0.029), higher NYHA score (OR = 1.623, P = 0.005), and the presence of coronary artery disease (OR = 2.475, P = 0.028) could effectively predict LVEF deterioration in patients with LBBB.</p><p><strong>Conclusions: </strong>Male gender, history of hypertension, high NYHA score, and the presence of CAD predict LVEF deterioration in patients with LBBB.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e16570"},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/86/ff/ircmj-17-02-16570.PMC4376987.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33188265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Iranian Women's Experiences of Health Information Seeking Barriers: A Qualitative Study in Kerman.","authors":"Alireza Nikbakht Nasrabadi, Sakineh Sabzevari, Tayebeh Negahban Bonabi","doi":"10.5812/ircmj.25156","DOIUrl":"https://doi.org/10.5812/ircmj.25156","url":null,"abstract":"<p><strong>Background: </strong>Women as active health information seekers play a key role in determining lifestyle and possible implementation of preventive measures, thereby improving the health of individuals, families and society. Although studies indicate that equipping people with adequate health information leads to optimal health outcomes, sometimes the complexity of human behavior and presence of barriers and limitations expose them to challenges.</p><p><strong>Objectives: </strong>This study was designed to explore women's experiences of health information seeking barriers.</p><p><strong>Patients and methods: </strong>In this qualitative content analysis study, data collection was conducted regarding inclusion criteria, through purposive sampling and semi-structured interviews with 17 women and using documentation and field notes until data saturation. Qualitative data analysis was performed constantly and simultaneously with data collection.</p><p><strong>Results: </strong>Five central themes were emerged to explain women's experiences of barriers to health information seeking as inadequate support from health care system, shame and embarrassment, costs, wrong ideas and beliefs and inadequate health literacy.</p><p><strong>Conclusions: </strong>It seems the accurate and evidence-based review of the current health system is crucial to support the health informative requirements in a community-based approach, respecting the community cultural-religious beliefs and client participation in health care and according to local resources.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e25156"},"PeriodicalIF":0.4,"publicationDate":"2015-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/17/a4/ircmj-17-02-25156.PMC4376996.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33182962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hasan Onur Arik, Mehmet Arican, Nesibe Kahraman Cetin, Umit Sarp
{"title":"Primary intraosseous hydatid cyst of femur.","authors":"Hasan Onur Arik, Mehmet Arican, Nesibe Kahraman Cetin, Umit Sarp","doi":"10.5812/ircmj.21070","DOIUrl":"https://doi.org/10.5812/ircmj.21070","url":null,"abstract":"<p><strong>Introduction: </strong>Echinococcosis is a parasitic and zoonotic disease of animals and humans. The cause is Echinococcus granulosus and occasionally, Echinococcus multilocularis. Hydatid cysts are mostly seen in the liver and lungs, although almost all organs and systemscan be involvement. Hydatid cysts seen with bone involvement comprise approximately 3% of all hydatid cysts. Even if a long period of survey is possible, it is still difficult to eradicate the disease and effect a cure.</p><p><strong>Case presentation: </strong>In this study, an evaluation was made of a patient referred at Yozgat State Hospital Orthopedics and Traumatology Polyclinic with complaints of pain in her left thigh close to the knee. After examinations of plain radiographs, computerized tomography, magnetic resonance images, and blood parameters, a diagnosis was made of left femoral intramedullary hydatid cyst from excised intraoperative material. Throughout a 6-month follow-up period, there was no recurrence and functional results were good.</p><p><strong>Conclusions: </strong>Based on this report (of a patient presented with an intramedullary cyst in the long bones), the primary bone hydatid cyst disease should be kept in mind and be investigated in the differential diagnosis.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e21070"},"PeriodicalIF":0.4,"publicationDate":"2015-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5812/ircmj.21070","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33061957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Atif Bayramoglu, Murat Saritemur, Sultan Tuna Akgol Gur, Mucahit Emet
{"title":"Demographic and clinical differences of aggressive and non-aggressive suicide attempts in the emergency department in the eastern region of Turkey.","authors":"Atif Bayramoglu, Murat Saritemur, Sultan Tuna Akgol Gur, Mucahit Emet","doi":"10.5812/ircmj.24666","DOIUrl":"https://doi.org/10.5812/ircmj.24666","url":null,"abstract":"<p><strong>Background: </strong>Worldwide, suicide ranks among the three leading causes of death among those aged 15-44 years. An estimated 800000 people die by committing suicide annually.</p><p><strong>Objectives: </strong>To better understand the association between aggressive suicidal attempt and non-aggressive suicidal attempt in patients with suicide attempt in the emergency department.</p><p><strong>Patients and methods: </strong>A cross-sectional observational study was conducted on suicide attempters of eastern region of Turkey between May 2008 and January 2012. Information of all adult suicide attempts was collected prospectively on a form. Suicide attempts were grouped as aggressive and non-aggressive attempts on a specially designed data-collection form. The aggressive suicide attempts contained violent suicide methods such as firearm, hanging, jumping, car exhaust or drowning.</p><p><strong>Results: </strong>A total of 533 patients were included. Sixty-four of these patients admitted to ED with aggressive suicide attempt (12%). Non-aggressive suicide attempts were consulted to psychiatry more compared to aggressive ones (%73.6, n = 345 vs. %32.8, n = 21, P < 0.0001). Agitation in ED and being male increased aggressive suicide attempt risk by 3.5 (%95 CI: 1.6-7.6) and 3.2 times (%95 CI: 1.8-5.5), agitated patients in ED group and male group respectively. Patients with aggressive suicide attempt were statistically more frequent among these patients; patients with agitation, those hospitalized in intensive care or surgical services and those whose length of stay in the emergency department was less than one day (P < 0.05 for all). Patients with non-aggressive suicide attempt were statistically more frequent in these patients; patients complained of nausea, vomiting, stomach pain, fatigue, those with confusion, those tending to sleep, those hospitalized in internal services or emergency ward and finally those whose length of stay in the emergency department was more than one day (P < 0.05 for all).</p><p><strong>Conclusions: </strong>Patients with aggressive suicide attempt who have high risk of dying should be recognized and requested psychiatric consultation even if not in the emergency department.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e24666"},"PeriodicalIF":0.4,"publicationDate":"2015-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f2/33/ircmj-17-02-24666.PMC4353187.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33147025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alireza Saied, Alia Ayatollahi Mousavi, Fateme Arabnejad, Afshin Ahmadzadeh Heshmati
{"title":"Tourniquet in surgery of the limbs: a review of history, types and complications.","authors":"Alireza Saied, Alia Ayatollahi Mousavi, Fateme Arabnejad, Afshin Ahmadzadeh Heshmati","doi":"10.5812/ircmj.9588","DOIUrl":"10.5812/ircmj.9588","url":null,"abstract":"<p><strong>Context: </strong>A tourniquet is a device that is used frequently in most orthopaedic surgeries but this routine device can lead to serious complications so we decided to review and declare it for safe instruction and use.</p><p><strong>Evidence acquisition: </strong>We searched the word \"tourniquet\" in PubMed and Google and reviewed all full text English articles and abstracts of non-English articles. In addition, we read all the reference pages of articles to find the new references.</p><p><strong>Results: </strong>The use of tourniquet in orthopedic surgery can lead to serious but rare complications that can be prevented by its correct knowledge and use.</p><p><strong>Conclusions: </strong>At present, there is not enough evidence to discontinue the routine uses of tourniquets.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e9588"},"PeriodicalIF":0.4,"publicationDate":"2015-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5812/ircmj.9588","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33147031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A comparative study of three speckle reducing methods for intima-media thickness ultrasound images.","authors":"Mehravar Rafati, Masoud Arabfard, Mehrdad Rafati Rahimzadeh, Hasan Voshtani, Hassan Moladoust","doi":"10.5812/ircmj.25013","DOIUrl":"https://doi.org/10.5812/ircmj.25013","url":null,"abstract":"<p><strong>Background: </strong>Ultrasonic evaluation of intima-media thickness (IMT) is an early marker of assessing the development of atherosclerosis and determining cardiovascular risk. To attain the best possible diagnosis, it is essential that medical images be clear, sharp and without noise and artifacts.</p><p><strong>Objectives: </strong>Comparison of speckle reducing anisotropic diffusion (SRAD), discrete (DTD) and continuum topological derivative (CTD) on B-mode ultrasound images of common carotid and brachial arteries throughout the cardiac cycle.</p><p><strong>Patients and methods: </strong>In a cross-sectional design, an examination was performed on forty-two human subjects with a mean age of 44 ± 6 years from April 2013 to June 2013. This study was approved by the ethics committees of Kashan University of Medical Sciences and Beheshti Hospital. An ultrasonic examination of common carotid and brachial arteries of forty-two human subjects was performed. The program was designed in MATLAB software to extract consecutive B-mode images and apply region of interest (ROI) on the IMT of the common carotid and brachial arteries. Then, three different noise reduction filters with the Canny edge detection were used in ROI separately. Finally, the program measured the image quality metrics.</p><p><strong>Results: </strong>According to values of eleven different image quality metrics (mentioned in the main text), there was a significant difference between CTD, DTD and SRAD filters with the Canny edge detection status in the common carotid and brachial arteries throughout the cardiac cycle (all P values < 0.001). For example, peak signal to noise ratios (PSNR) using CTD, DTD and SRAD filters were 95.43 ± 0.64, 88.86 ± 0.82 and 73.02 ± 0.20 in common carotid and 96.39 ± 1.25, 92.58 ± 0.11 and 88.27 ± 0.63 in brachial arteries, respectively (both P values < 0.001).</p><p><strong>Conclusions: </strong>By measuring image quality metrics, this study showed that DTD and CTD filters with the Canny edge detection respectively, are better than SRAD filter with the Canny detection for speckle suppression and details preservation in both arteries in the ultrasound images.</p>","PeriodicalId":14628,"journal":{"name":"Iranian Red Crescent Medical Journal","volume":"17 2","pages":"e25013"},"PeriodicalIF":0.4,"publicationDate":"2015-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/10/ircmj-17-02-25013.PMC4376986.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33061962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}