莪术对精子发生的影响。

IF 0.4 4区 医学
Iranian Red Crescent Medical Journal Pub Date : 2015-02-21 eCollection Date: 2015-02-01 DOI:10.5812/ircmj.18668
Arash Khaki
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引用次数: 29

摘要

背景:在今天的现代国家,草药被认为有助于治疗各种疾病,作为抗氧化剂和矿物质的丰富来源。目的:研究莪术对大鼠精子发生的影响。材料与方法:本实验将Wistar雄性大鼠(n = 20)分为对照组(n = 10)和肉桂组(n = 10)。肉桂组给予75 mg/kg/天的肉桂灌胃,连续28天;对照组每天给予等量蒸馏水。动物饲养在标准化的条件下。第28天,每只大鼠尾区采血5 mL,测定睾酮、超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GPX)和丙二醛(MDA)水平。收集睾丸,然后准备用世卫组织方法进行精子分析。结果:肉桂组精子质量指标、血清总睾酮、SOD、CAT、GPX水平均显著高于对照组(P < 0.05)。与对照组相比,肉桂组大鼠血浆MDA水平显著降低(P < 0.05)。各组间睾丸重量差异不显著(P > 0.05)。结论:75 mg/kg/d肉桂可显著提高哺乳动物精子数量、活力和活力,支持肉桂对精子发生有益的理论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Cinnamomum zeylanicumon on Spermatogenesis.

Background: In modern countries today, herbal medicines are known to help in the treatment of various diseases, as rich sources of antioxidants and minerals.

Objectives: To study the effect of Cinnamomum zeylanicum (C. zeylanicum) on spermatogenesis in rats.

Materials and methods: In this experimental study, Wistar male rats (n = 20) were divided into two groups, a control group (n = 10) and a Cinnamomum zeylanicum group (n = 10). The subjects in the cinnamon group received 75 mg/kg/day cinnamon by gavage for 28 days, while the controls received an equal volume of distilled water daily. Animals were kept in standardized conditions. On day 28, a 5 mL blood sample from each rat was taken from tail area to measure testosterone, superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), and malondialdehyde (MDA) levels. Testes were collected and were then prepared for sperm analysis by the WHO method.

Results: Sperm quality parameters, total serum testosterone, SOD, CAT, and GPX levels were significantly increased in the cinnamon group in comparison to controls (P < 0.05). Also, rats in the cinnamon group showed a significant decrease in the level of plasma MDA (P < 0.05) in comparison to controls. There were no significant differences between the groups in testis weight (P > 0.05).

Conclusions: The administration of 75 mg/kg/day cinnamon significantly increased the sperm population, motility and viability, which supports the theory that in mammalians, cinnamon has a beneficial effect on spermatogenesis.

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来源期刊
Iranian Red Crescent Medical Journal
Iranian Red Crescent Medical Journal 医学-医学:内科
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期刊介绍: The IRANIAN RED CRESCENT MEDICAL JOURNAL is an international, English language, peer-reviewed journal dealing with general Medicine and Surgery, Disaster Medicine and Health Policy. It is an official Journal of the Iranian Hospital Dubai and is published monthly. The Iranian Red Crescent Medical Journal aims at publishing the high quality materials, both clinical and scientific, on all aspects of Medicine and Surgery
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