Investigative ophthalmology & visual science最新文献

{"title":"Surface-Specific Internal Limiting Membrane Biomechanics in Epiretinal Membrane Severity and Visual Outcomes.","authors":"Changsik Yoon, Sangkyung Choi, Yeseul Yoon, Gi Young Kong, Byung Gil Moon, Byung Yang Lee, Hyun Seung Yang","doi":"10.1167/iovs.67.12.14","DOIUrl":"10.1167/iovs.67.12.14","url":null,"abstract":"<p><strong>Purpose: </strong>To determine whether surface-specific biophysical properties of the internal limiting membrane (ILM), measured by atomic force microscopy (AFM), are associated with optical coherence tomography (OCT)-based epiretinal membrane (ERM) stage and six-month visual outcomes.</p><p><strong>Methods: </strong>In this prospective study, ILM specimens from vitrectomy for idiopathic ERM (stages 2-4) were examined by AFM for thickness, roughness, stiffness, and adhesion on the vitreal or retinal surface. AFM parameters were related to preoperative OCT parameters, best-corrected visual acuity, surgical grade of ILM adherence, and six-month outcomes. Multivariable regression assessed correlates of visual change and final acuity.</p><p><strong>Results: </strong>We analyzed 147 eyes (80 retinal-side, 67 vitreal-side). Retinal-side roughness and stiffness exceeded vitreal-side values (both P < 0.001). Retinal-side roughness and adhesion (P < 0.001 and P = 0.008, respectively) and, less strongly, vitreal-side stiffness (P = 0.035) increased with ERM stage, whereas vitreal-side adhesion did not. Thickness did not differ by surface or stage (all P ≥ 0.116). Retinal-side roughness and adhesion correlated with preoperative severity and postoperative outcomes, whereas vitreal-side stiffness correlated mainly with severity and vitreal-side adhesion with surgical adherence. Greater retinal-side adhesion and vitreal-side stiffness were associated with smaller visual gains and worse final acuity in multivariable models (all P < 0.05).</p><p><strong>Conclusions: </strong>ILM biophysical properties showed surface-specific associations with OCT-based ERM severity and six-month visual outcomes. Retinal-side adhesion and vitreal-side stiffness remained associated with final acuity after adjustment for baseline acuity. These findings suggest that ILM surface mechanics may reflect ERM-related retinal deformation relevant to postoperative visual recovery.</p>","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"14"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allelic Architecture and Clinical Spectrum of RP1-Associated Retinal Dystrophies in a Multicenter Korean Cohort.","authors":"Yunnie Cho, Kwangsic Joo, Sohee Jeon, Eun Kyoung Lee, Jae Shin Song, Sungsoon Hwang, Jinu Han, Jay Jiyong Kwak, Suk Ho Byeon, Min Kim, Yong Joon Kim, Junwon Lee, Chang Ki Yoon, Min Sagong, Areum Jeong, Mirinae Kim, Ji Hye Lee, Hyewon Chung, Hyeong Min Kim, Dong Ho Park, Sang Jin Kim, Christopher Seungkyu Lee, Se Joon Woo","doi":"10.1167/iovs.67.12.17","DOIUrl":"10.1167/iovs.67.12.17","url":null,"abstract":"<p><strong>Purpose: </strong>To define the allelic architecture and phenotypic spectrum of RP1-associated retinal dystrophies in a large Korean cohort, emphasizing recurrent truncating alleles, phasing of linked variants, and mobile-element insertions (MEIs) underdetected by standard next-generation sequencing.</p><p><strong>Methods: </strong>This retrospective multicenter study included 143 patients with RP1-associated retinopathy sequenced at eight centers in Korea (2002-2025). Clinical findings, multimodal imaging, and electrophysiology were evaluated. Structural variants and allelic phase were assessed using an integrative genomics viewer-based soft-clipping review, Alu-PCR, and long-read whole-genome sequencing (lrWGS) in selected cases. Patients were classified as autosomal-dominant retinitis pigmentosa (AD-RP), autosomal-recessive RP (AR-RP), or recessive macular or cone(-rod) dystrophies.</p><p><strong>Results: </strong>Twenty-seven RP1 variants were identified, including nine novel alleles. All AD-RP cases were explained by seven exon 4 truncations within the dominant cluster. AR disease was dominated by three highly recurrent truncating alleles: c.4196del (p.Cys1399Leufs*5, carried by 32.2% of patients), the hypomorphic truncation c.5797C>T (p.Arg1933*, 30.8%), and c.6181del (p.Ile2061Serfs*12, 31.5%). The downstream missense variant c.6353G > A (p.Ser2118Asn) was consistently observed in cis with c.4196del, whereas c.4196del also occurred independently; this phase relationship was confirmed by lrWGS. The Alu insertion c.4052_4053ins328 (p.Tyr1352Alafs*9) was carried by 14% of patients. AR-RP presented earlier (mean onset 16.9 vs. 33.5 years, P < 0.001) and had poorer baseline worse-eye best-corrected visual acuity (logMAR, 1.05 vs. 0.44, P = 0.002) than AD-RP.</p><p><strong>Conclusions: </strong>This large ancestry-specific RP1-associated retinal dystrophy cohort refines the allelic landscape and underscores the importance of phasing and MEI-aware testing strategies, revealing broad phenotypic expansion to macular and cone(-rod) dystrophies and genotype-dependent severity profiles.</p>","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"17"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149136532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retinal Flattening Associated With Photoreceptor Degeneration Leads to the Formation of Staphyloma-Like Morphology in Retinitis Pigmentosa.","authors":"Yuki Yamabe, Shotaro Fujibayashi, Hiroshi Ichinohe, Shoma Hara, Eitaro Imura, Taiga Inooka, Taro Kominami, Junya Ota, Yasuki Ito, Hiroko Terasaki, Shinji Ueno","doi":"10.1167/iovs.67.12.29","DOIUrl":"10.1167/iovs.67.12.29","url":null,"abstract":"<p><strong>Purpose: </strong>A staphyloma-like morphology has been reported in eyes with retinitis pigmentosa (RP). We investigated retinal curvature in RP using widefield swept-source optical coherence tomography and explored the mechanisms underlying this abnormal morphology.</p><p><strong>Methods: </strong>This retrospective study included 74 eyes with RP and 40 control eyes, all with axial lengths of 22 to 26 mm. The curvature of Bruch's membrane was analyzed in the central and peripheral regions of all eyes. In 37 RP eyes with an ellipsoid zone (EZ) length ≥ 1.5 mm, curvature was further evaluated in EZ-preserved and EZ-defected areas and across the EZ boundary.</p><p><strong>Results: </strong>Central macular curvature was significantly steeper in RP eyes (-23.55 ± 17.56 × 10⁻5 µm⁻1) than in controls (-7.72 ± 6.46 × 10⁻5 µm⁻1), whereas the peripheral retina was significantly flatter in RP (-6.84 ± 10.18 × 10⁻5 µm⁻1, inferior) than in controls (-15.14 ± 4.76 × 10⁻5 µm⁻1). Curvature was steeper in EZ-preserved areas (-30.40 ± 24.34 × 10⁻5 µm⁻1) than in EZ-defected areas (-8.00 ± 6.40 × 10⁻5 µm⁻1). Around the EZ edge, curvature on the central side was significantly steeper than that on the peripheral side.</p><p><strong>Conclusions: </strong>In RP, retinal curvature flattens with photoreceptor degeneration, resulting in relatively steep concavity in the central macula or EZ-preserved regions. These findings suggest that photoreceptor loss contributes to secondary alterations in global retinal and ocular configuration.</p>","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"29"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13676243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149193826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting Endoplasmic Reticulum Stress With Exogenous GDNF Promotes Diabetic Corneal Epithelial and Neural Repair via PI3K/AKT Signaling.","authors":"Haoyu Li, Jianfeng Long, Shirui Dai, Wentao Han, Liwei Zhang, Baihua Chen","doi":"10.1167/iovs.67.12.24","DOIUrl":"10.1167/iovs.67.12.24","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates the therapeutic potential and the core signaling associated with glial cell line-derived neurotrophic factor (GDNF) in alleviating diabetic keratopathy (DK).</p><p><strong>Methods: </strong>In vitro, human corneal epithelial cells (HCECs) were subjected to glucolipotoxic stress to simulate the type 2 diabetes mellitus (T2DM) microenvironment, with or without GDNF and PI3K/AKT pathway modulators. In vivo, a T2DM mouse model was established using a combination of high-fat diet feeding and streptozotocin administration, and recombinant GDNF was administered subconjunctivally. Cellular functions were evaluated using standard assays. Protein expressions in HCECs, murine corneas, and trigeminal ganglia (TG) were quantified via Western blotting. Ultrastructural endoplasmic reticulum (ER) alterations were observed using transmission electron microscopy. Clinical evaluations, including fluorescein staining, mechanical sensitivity, and wound healing rates were systematically conducted alongside whole-mount corneal nerve immunolabeling.</p><p><strong>Results: </strong>GDNF intervention effectively restored the impaired proliferative and migratory capacities of HCECs, attenuated apoptosis, and alleviated ER stress induced by glucolipotoxicity. Notably, pharmacological inhibition of the PI3K/AKT pathway significantly abrogated these protective effects. In vivo, subconjunctival GDNF administration expedited epithelial restoration, stimulated subbasal nerve regrowth, and rescued sensitivity within the diabetic murine cornea. Furthermore, exogenous GDNF successfully mitigated ER stress and reactivated the suppressed PI3K/AKT signaling cascade in both the corneal epithelium and the corresponding TG.</p><p><strong>Conclusions: </strong>Exogenous GDNF significantly accelerates epithelial restoration while concurrently driving neural regeneration within the diabetic cornea. These dual protective effects are mechanistically driven by the reactivation of the PI3K/AKT signaling axis to mitigate ER stress.</p>","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"24"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13676247/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual Mechanisms of Impaired Visual Processing in Glaucoma: Insights From Resting-State and Task-Related EEG.","authors":"Xiaolin Mei, Lilin Chen, Lok Hin Chan, Anqi Lyu, Celia Tsang, Christopher Leung, Benjamin Thompson, Allen M Y Cheong","doi":"10.1167/iovs.67.12.2","DOIUrl":"10.1167/iovs.67.12.2","url":null,"abstract":"<p><strong>Purpose: </strong>To examine both resting-state and task-related electroencephalography (EEG) changes associated with visual processing in glaucoma.</p><p><strong>Methods: </strong>Thirty glaucoma patients (mean age, 63 ± 8.26 years; visual field mean deviation, -15.41 ± 6.34 dB) and 28 age-matched controls (62.86 ± 9.19 years) underwent resting-state EEG for 3 minutes under eyes-open and eyes-closed conditions. Alpha suppression, calculated as the difference between conditions, was assessed as a measure of cognitive state transition capacity. Visual evoked potentials (VEPs) were recorded using a 64-channel EEG system during a checkerboard reversal task under monocular and binocular viewing.</p><p><strong>Results: </strong>Resting-state EEG revealed that significantly reduced alpha suppression was highly specific to a high-alpha subband (10.0-12.9 Hz; P < 0.001), and low-alpha (7.0-9.9 Hz) modulation remained intact in the glaucoma group. Task-related EEG showed delayed latency and reduced amplitude in both P100 and N75-P100 components in the glaucoma group, indicating impaired visual processing. Effect size analysis indicated that P100 amplitude and N75-P100 latency showed the largest group differences, highlighting these as the most prominent cortical changes. Notably, alpha suppression deficits showed no significant correlation with glaucoma severity or VEP parameters, suggesting distinct neurophysiological mechanisms beyond direct visual pathway damage.</p><p><strong>Conclusions: </strong>Both resting-state and task-related EEG measures differed between the glaucoma and control groups, indicating alterations in cortical activity and visual-pathway responses. Specifically, the localized high alpha modulation deficit suggests altered top-down visual network dynamics in glaucoma.</p>","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"2"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13648562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Divergence Between Marker Expression and Phenotype During Human Corneal Endothelial Cell Expansion.","authors":"Filippo Bonelli, Tom Bailey, Iveta Dzivite, Lieve Temmerman, Mor Dickman, Vanessa LaPointe","doi":"10.1167/iovs.67.12.10","DOIUrl":"10.1167/iovs.67.12.10","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to compare whether conventional marker-based assessments adequately reflect phenotypic stability during serial passaging of two established culture protocols for primary human corneal endothelial cells (CEnCs).</p><p><strong>Methods: </strong>Primary CEnCs were isolated from paired donor corneas from 25 individuals (18-44 years of age), and were cultured using 2 established methods. Cells were evaluated at passages 0 to 2 using quantitative morphology (cell area, form factor, nucleus-to-cytoplasm ratio, and cell density), RT-qPCR of endothelial-associated genes, flow cytometry, immunofluorescence, and ELISA quantification of secreted thrombospondin-2 (TSP2). Statistical comparisons were performed using 1- or 2-way ANOVA with multiple comparisons (P < 0.05).</p><p><strong>Results: </strong>CEnCs cultured with method 1 maintained higher cell density, smaller cell area, and greater hexagonality across passages compared with method 2 (P < 0.01 to P < 0.0001). In contrast, transcript levels of selected endothelial-associated markers (ATP1A1 and TJP1) and ZO-1 protein expression were higher in method 2 at later passages (P < 0.01), despite progressive morphological deterioration and loss of membrane localization. Proteins associated with loss of the CEnC phenotype (CD44 and CD10) were significantly elevated in method 2 (P < 0.05 to P < 0.0001), and TSP2 secretion was increased at passage 2 (P < 0.001). Across both methods, most canonical endothelial genes were ≥75% downregulated compared with native tissue.</p><p><strong>Conclusions: </strong>Culture-induced phenotypic drift can occur in CEnCs despite preserved canonical endothelial marker expression. Divergence among marker expression, morphology, localization, and endothelial-to-mesenchymal transition (EndMT) readouts highlights the limits of marker-based evaluation alone. Integrated, multidimensional phenotyping should guide assessment of cultured CEnCs and optimization of expansion protocols, although functional validation is needed to link these readouts to endothelial performance.</p>","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"10"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroprotective and Anti-Inflammatory Effects of SOCS1 Mimetic Peptides in Mouse Diabetic Retinopathy.","authors":"Elena Salobrar-García, Lucas Opazo-Ríos, José A Matamoros, Lidia Sánchez-Puebla, José A Fernández-Albarral, Juan J Salazar, Raquel Castro, Manuel Soto-Catalán, Juan Antonio Moreno, Carmen Gómez-Guerrero, Sebastián Mas, Jesús Egido, Ana I Ramírez","doi":"10.1167/iovs.67.12.21","DOIUrl":"10.1167/iovs.67.12.21","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the therapeutic potential of a suppressor of cytokine signaling 1 (SOCS1) mimetic peptide (MiS1) via systemic administration in a mouse model of diabetic retinopathy (DR).</p><p><strong>Methods: </strong>Male db/db mice, a model of type 2 diabetes, were treated for 7 weeks with intraperitoneal injections of MiS1. In comparison, a group of animals received the Janus kinase (JAK)1/2 inhibitor baricitinib. Untreated diabetic db/db mice and non-diabetic db/m littermates served as controls. Retinal structure was assessed in vivo by optical coherence tomography. Retinal ganglion cell (RGC) survival (Brn3a+ cells) and Iba1-positive microglial activation (Iba1+ cells) were analyzed by immunohistochemistry in retinal wholemounts.</p><p><strong>Results: </strong>Untreated db/db mice exhibited retinal thinning, RGC loss, and marked Iba1+ microglial activation. Both MiS1 and baricitinib treatments significantly attenuated retinal thinning, with MiS1 preserving retinal thickness at levels comparable to those of nondiabetic controls. RGC numbers were partially preserved in both treated groups, although the increase compared with untreated db/db mice reached statistical significance only in baricitinib-treated animals. Both treatments improved microglial morphology, mainly by increasing arbor area, whereas their effects on Iba1+ cell numbers were layer and parameter dependent.</p><p><strong>Conclusions: </strong>Systemic administration of the SOCS1 mimetic peptide MiS1 showed a consistent protective profile on retinal thickness preservation and microglial remodeling in experimental DR. These findings support SOCS1-based therapies as a promising therapeutic strategy.</p>","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"21"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13676220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149181994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Changes in Choroidal Thickness Across the Eye in Young Children With Premyopia.","authors":"Karen Flores, Aidan McCullough, Zhihui She, Nimesh B Patel, Fuensanta A Vera-Diaz","doi":"10.1167/iovs.67.12.15","DOIUrl":"10.1167/iovs.67.12.15","url":null,"abstract":"<p><strong>Background: </strong>The choroid is thought to be implicated in eye growth regulation, yet longitudinal choroidal data in young children are limited.</p><p><strong>Methods: </strong>Choroidal thickness (ChT) was measured in 92 children with functional emmetropia (baseline age, 7.4 ± 0.8 years; cycloplegic refractive error, +1.01 ± 0.55 diopters) enrolled in the 3-year PICNIC (Preventing Myopia: Investigating Contributing Factors to Nearsightedness in Children) study. Wide-field spectral domain OCT radial scans (12-line, enhanced depth imaging) were segmented using a neural network and sampled at annular eccentricities (1, 3, 6, 10, and 14 mm) in four quadrants (temporal, superior, nasal, and inferior). A generalized linear mixed model evaluated the effects of risk group (low risk vs. high risk, based on baseline hyperopic reserve and parental myopia), eccentricity, quadrant, visit, axial length (AXL), and age. A separate linear mixed model was used to assess the preonset ChT in children who developed myopia.</p><p><strong>Results: </strong>After adjustment for age and AXL, ChT decreased with eccentricity and varied by quadrant (P < 0.001). ChT increased across visits (P < 0.001), whereas greater AXL was independently associated with a thinner ChT (P < 0.001). No main effect of risk group was observed (P > 0.20); however, a significant Risk group × Eccentricity × Quadrant interaction (P < 0.001) indicated distinct spatial profiles with low-risk children, who exhibited thicker choroids, whereas children at high risk showed steeper thinning. In the preonset analysis, the mean ChT did not differ between future myopes and persistent nonmyopes (P = 0.16), but a significant Myopia status × Eccentricity interaction (P < 0.01) indicated thinner choroids before onset.</p><p><strong>Conclusions: </strong>Choroidal remodeling in early childhood is spatially patterned. Although the global ChT did not differ by risk group, altered spatial profiles were evident in high-risk children and future myopes before clinical onset. These results support a potential role for wide-field spatial metrics in the identification of early structural susceptibility to myopia.</p>","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"15"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13657124/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum in: Visual Snow Is Susceptible to the Motion Aftereffect.","authors":"","doi":"10.1167/iovs.67.12.35","DOIUrl":"https://doi.org/10.1167/iovs.67.12.35","url":null,"abstract":"","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"35"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum in: Elevated Nasal-Temporal Asymmetry of the Choroidal Vascular Index in Pathologically Myopic Eyes.","authors":"","doi":"10.1167/iovs.67.12.36","DOIUrl":"https://doi.org/10.1167/iovs.67.12.36","url":null,"abstract":"","PeriodicalId":14620,"journal":{"name":"Investigative ophthalmology & visual science","volume":"67 12","pages":"36"},"PeriodicalIF":5.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}