Firouzeh Moeinzadeh, Marjan Mansourian, Mojgan Mortazavi, Shiva Seirafian, Shahrzad Shahidi, Zahra Tasdighi, Sahar Vahdat, Shahram Taheri, Mohammad Hossein Rouhani, Mohammad Saleki, Mostafa Rezaei, Mohammad Hossein Masoudi, Zahra Zamani, Nahid Rafie
{"title":"Chronic Kidney Disease in Isfahan Province, Action Plan for Screening in A Population-based Study.","authors":"Firouzeh Moeinzadeh, Marjan Mansourian, Mojgan Mortazavi, Shiva Seirafian, Shahrzad Shahidi, Zahra Tasdighi, Sahar Vahdat, Shahram Taheri, Mohammad Hossein Rouhani, Mohammad Saleki, Mostafa Rezaei, Mohammad Hossein Masoudi, Zahra Zamani, Nahid Rafie","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>We intended to explore the prevalence of chronic kidney disease (CKD) and its different stages, as well as CKD associated variables in the adult population in Isfahan province, Iran.</p><p><strong>Methods: </strong>Adults aged ≥ 18 were recruited in a cross-sectional study from 2017 to 2019. Data including demographics, anthropometrics, and laboratory findings were collected from each subject. The equation of chronic kidney disease- Epidemiology Collaboration (CKD-EPI) was used to estimate glomerular filtration rate (eGFR), and eGFR and UACR values were utilized to determine the stages of CKD.</p><p><strong>Results: </strong>Data from a total of 3374 subjects was analyzed. The mean age of participants was 49.3 ± 14.09 years and 59.3% were female. The prevalence of CKD was 18.5%. Only 0.25 and 3.5% of the population were in CKD stage 3 and 4, while most of the patients were in CKD stage 2 (7.6%) and stage 1 (7.1%). CKD patients were mostly on refined grains diet and used lesser dairy products compared to healthy participants. Variables including systolic blood pressure (OR = 1.018; P < .001), diastolic blood pressure (OR = 1.005; P < .05), fasting blood sugar (OR = 1.011; P < .001), female sex (OR = 1.319; P < .05), body mass index (OR = 1.030; P < .05), married status (OR = 1.335; P < .05), and smoking (OR = 1.529; P < .05) were significantly associated with increased risk of CKD in the logistic regression analysis.</p><p><strong>Conclusion: </strong>According to our results, the prevalence of CKD, especially stages 1 and 2, is quite high in central part of Iran. These findings help us to improve the screening for CKD patients and perform larger scale studies to identify the challenges ahead. DOI: 10.52547/ijkd.7201.</p>","PeriodicalId":14610,"journal":{"name":"Iranian journal of kidney diseases","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9112187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Virulence Factors of Staphylococcus Aureus Hemolysin HLA and HLB Isolated from Catheters of Dialysis Patients Referred to Nikan Hospital in Tehran During the Spring and Summer of 2021.","authors":"Mehrdad Jafari Fesharaki, Sara Alipanahi, Nazila Arbabsoleimani, Fatemeh Pourrezagholi, Zeinab Piravar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Staphylococcus aureus (S. aureus) is one of the most frequent causes of infection around the world. Insertion of intravascular catheter and formation of biofilms by methicillinresistant Staphylococcus aureus (MRSA) have contributed to the increased risk of infection, and morbidity and mortality rates. Biofilms formation on intravascular catheters and other medical devices are of major postoperative concerns because biofilms are often the source of persistent and difficult-to-treat bacterial infections. This study aimed to evaluate different genetic patterns of this bacterium in samples collected from dialysis patients of Nikan hospital.</p><p><strong>Methods: </strong>In this descriptive cross-sectional study 30 samples from the removed catheters of patients suspected to have S. aureus infection and admitted to the dialysis ward of Nikan hospital were collected and phenotypic evaluations were done to confirm the type of the infectious species. Evaluation of antibiotic resistance of bacterial samples using Kirby-Bauer method was done. Biofilm production of the samples was assessed by the 96-plate microtiter method. The existence of two genes hla and hlb were evaluated using Multiplex PCR.</p><p><strong>Results: </strong>The biofilm production test showed that 60% of the samples were able to produce strong biofilms. Multiplex PCR results revealed that both hla and hlb genes were expressed in 93% of the samples, while, hlb gene alone was expressed in 53% of cases.</p><p><strong>Conclusion: </strong>The results of this study provide significant insight into the virulence gene makeup of catheter-colonizing S. aureus strains, and will assist in developing a more targeted treatment approach for persistent S. aureus biofilm contamination of medical devices. DOI: 10.52547/ijkd.7146.</p>","PeriodicalId":14610,"journal":{"name":"Iranian journal of kidney diseases","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9112189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Revisiting the Management of Pediatric Kidney Transplants, \u0000A Multicenter Analysis","authors":"Farahnak Assadi, Nakysa Hooman, Abdolhassan Seyedzadeh, Anoush Azarfar, Elaheh Malakan Rad, Behnaz Bazargani, Arash Abasi, Mastaneh Moghtaderi, Afshin Safaeiasl, Nasrin Esfandiar, Ali Derakhsan, Hamidreza Badeli, Alireza Eskandarifar, Mojgan Mazaheri, Fatemeh Ghane Sharbaf","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The newest Kidney Disease Improving Global Outcomes (KDIGO) guideline recommendations were investigated mainly for the care of adult kidney transplant recipients, but no guideline exists for the management of pediatric transplant recipients. This review provides update recommendations in the management of pediatric kidney transplantation. Four electronic databases, PubMed, EMBASE, Google Scholar, and Web of Science were searched systematically for the last two decades, using Mesh terms in English language. The Grades of Recommendation Assessment, Development, and Evaluation (GRADE) approach was used for grading the quality of the overall evidence and the strength of recommendations for each outcome across the studies. The overall quality of evidence categorized as high (A), moderate (B), low (C), or poor (D). The strength of a recommendation was determined as level 1 (recommended) or level 2 (suggested). The ungraded statements were determined on the basis of common sense to provide general advice. Of the 317 citations which were screened for the evidence review, 62 were included in data extraction. The included studies were randomized controlled trials, prospective cohorts and cross-sectional, descriptive, and review studies. Of the 115 statements, 56 (48.6%) were graded 1 (we recommend), 34 (29.5%) were graded 2 (we suggest), and 25 (21.7%) were ungraded statements. Altogether, only 22 (19.1%) of recommendations reached the \"A\" or \"B\" levels of quality of evidence. The pediatric kidney transplant recipients are different from adult recipients regarding the primary kidney diseases, surgical techniques, drug metabolism, adherence to medications, growth and neurocognitive development and immunization needs prior to transplantation. DOI: 10.52547/ijkd.7179.</p>","PeriodicalId":14610,"journal":{"name":"Iranian journal of kidney diseases","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9117134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}