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sEMG Signal-Based Lower Limb Movements Recognition Using Tunable Q-Factor Wavelet Transform and Kraskov Entropy 基于可调q因子小波变换和Kraskov熵的表面肌电信号下肢运动识别
IF 4.8 4区 医学
Irbm Pub Date : 2023-08-01 DOI: 10.1016/j.irbm.2023.100773
C. Wei, H. Wang, B. Zhou, N. Feng, F. Hu, Y. Lu, D. Jiang, Z. Wang
{"title":"sEMG Signal-Based Lower Limb Movements Recognition Using Tunable Q-Factor Wavelet Transform and Kraskov Entropy","authors":"C. Wei,&nbsp;H. Wang,&nbsp;B. Zhou,&nbsp;N. Feng,&nbsp;F. Hu,&nbsp;Y. Lu,&nbsp;D. Jiang,&nbsp;Z. Wang","doi":"10.1016/j.irbm.2023.100773","DOIUrl":"https://doi.org/10.1016/j.irbm.2023.100773","url":null,"abstract":"<div><h3>Background</h3><p><span>The recognition of lower limb movement has a wide range of applications in rehabilitation training, wearable exoskeleton control, and human activity monitoring. </span>Surface electromyography (sEMG) signals can directly reflect the intention of human movement and can be used as the source of lower limb movement recognition. Literature reports have shown that extracting features from sEMG signals is the core of human movement recognition based on sEMG signals. However, how to effectively extract features from the sEMG signal of the lower limbs affected by body gravity is a difficult problem for the recognition of lower limb movement based on the sEMG signal.</p></div><div><h3>Objectives</h3><p>The main objective of this paper is to propose an efficient lower limb movement recognition model based on sEMG signals to accurately recognize the four lower limb movements.</p></div><div><h3>Methods and results</h3><p>We proposed a novel method of lower limbs movements recognition based on tunable Q-factor wavelet transform (TQWT) and Kraskov entropy (KrEn). Firstly, the sEMG signals of four different lower limb movements from twenty subjects were recorded by seven wearable sEMG signal sensors, and the recorded sEMG signals were denoised by multi-scale principal component analysis (MSPCA). Then, the denoised sEMG signal is decomposed into multiple sub-band signals by TQWT and the KrEn feature is extracted from each sub-band signal. Next, the representative features are selected from the extracted KrEn features by the minimum redundancy maximum relevance (mRMR) feature selection method. Finally, the four lower limb movements are recognized by three machine learning classifiers. Besides, to improve the recognition performance, a majority voting (MV) technology is proposed for the post-processing of decision flow. Experimental results show that the combination of TQWT, KrEn, and MV technology achieved the average recognition accuracy of 98.42% using the linear discriminant analysis (LDA) classifier.</p></div><div><h3>Conclusion</h3><p>The method proposed in this paper can recognize lower limb movements with high accuracy. Compared with existing methods, this method is more advanced and accurate, indicating that it has great application potential in rehabilitation training, wearable exoskeleton control, and daily activity monitoring.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49700833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Biomechanical Response of Four Roussouly's Sagittal Alignment Lumbar to Degeneration of Different Parts of Intervertebral Disc: Finite Element Model Analysis 四个Roussouly矢状位腰椎对椎间盘不同部位退变的生物力学响应:有限元模型分析
IF 4.8 4区 医学
Irbm Pub Date : 2023-08-01 DOI: 10.1016/j.irbm.2023.100772
W. Wang , F. Pan , P. Wang , W. Wang , Y. Wang , C. Kong , S. Lu
{"title":"Biomechanical Response of Four Roussouly's Sagittal Alignment Lumbar to Degeneration of Different Parts of Intervertebral Disc: Finite Element Model Analysis","authors":"W. Wang ,&nbsp;F. Pan ,&nbsp;P. Wang ,&nbsp;W. Wang ,&nbsp;Y. Wang ,&nbsp;C. Kong ,&nbsp;S. Lu","doi":"10.1016/j.irbm.2023.100772","DOIUrl":"https://doi.org/10.1016/j.irbm.2023.100772","url":null,"abstract":"<div><h3>Background</h3><p>Spinal degeneration with age is commonly accompanied by excessive kyphosis and low-back pain, however, little is known about the connection between lumbar sagittal morphology and its degenerative biomechanics. This study investigates the biomechanical response of four Roussouly's sagittal alignment lumbar to degeneration of various parts of the intervertebral disc (IVD) based on threedimensional finite element (FE) models.</p></div><div><h3>Methods</h3><p>Using Roussouly's type parametric FE models, material properties of the degenerate nucleus populous (NP), annulus fibrosis matrix (AFM), and collagen fibers were assumed to be half of the intact IVD. A follower preload and vertical force were applied to simulate physical standing posture.</p></div><div><h3>Results</h3><p>the reduced strength of the NP and AFM led to the increase of lumbar anteflexion, while the fiber mechanical properties have little effect on it. When facing IVD degeneration, Type 1 lumbar showed increased intradiscal pressures (IDPs) and fiber stress at the L1-2 and L4-S1 segments. Type 2 lumbar exhibited the highest lumbar anteflexion and pelvic rearward rotation, as well as increased IDPs among the models. Type 3 lumbar had the best biomechanical stability. Type 4 lumbar showed the higher AFM stress but the lower IDPs among the four types.</p></div><div><h3>Conclusions</h3><p>IVD degeneration generated sagittal imbalance by increasing lumbar anteflexion movement (i.e., loss lordosis) and pelvic rearback rotation. The biomechanical response of the four Roussouly's lumbar types differed in intervertebral rotation and stress distribution.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49700877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Application of the Coupling Angle to Investigate Upper Limb Interjoint Coordination After Stroke 应用耦合角研究中风后上肢关节间协调性
IF 4.8 4区 医学
Irbm Pub Date : 2023-08-01 DOI: 10.1016/j.irbm.2023.100769
S.G. Rozevink , K.A. Horstink , C.K. van der Sluis , J.M. Hijmans , A. Murgia
{"title":"Application of the Coupling Angle to Investigate Upper Limb Interjoint Coordination After Stroke","authors":"S.G. Rozevink ,&nbsp;K.A. Horstink ,&nbsp;C.K. van der Sluis ,&nbsp;J.M. Hijmans ,&nbsp;A. Murgia","doi":"10.1016/j.irbm.2023.100769","DOIUrl":"https://doi.org/10.1016/j.irbm.2023.100769","url":null,"abstract":"<div><h3>Objective</h3><p>Interjoint coordination after stroke is affected, which limits the use of the upper limb. Current methods to determine interjoint coordination lack the ability to visualize and quantify the movement. Therefore we investigated if the coupling angle can be used to visualize and interpret upper limb interjoint coordination following a stroke.</p></div><div><h3>Methods</h3><p>Seven chronic stroke patients trained six weeks with an assistive home-training system (MERLIN). Kinematic outcomes, i.e. elbow and shoulder range of motion, movement duration, and angle-angle plots were determined in a retrieving task. Interjoint coordination between elbow flexion and shoulder abduction angles was expressed as the coupling angle phases and the number of phase transitions: proximal/distal joint leading phase, in-phase and anti-phase. Comparisons were made within sides: pre-test versus post-test, and between sides: most-affected (MA) versus least-affected (LA).</p></div><div><h3>Results</h3><p>Smaller elbow flexion angles were found PreMA versus PreLA, and smaller shoulder abduction angles in PostMA versus PostLA. A general coordination pattern was revealed on the LA side, but not on the MA side. A trend showed less phase transitions at the MA side after training, suggesting a smoother movement. Quantification of the movement phases indicated more involvement of the shoulder joint involvement in the MA side during pre-test. After training, these differences were not apparent, which might reveal an increased independent control of the elbow joint.</p></div><div><h3>Conclusions</h3><p>The coupling angle and the movement phases provide a promising tool to investigate post-stroke interjoint coordination patterns.</p></div><div><h3>Significance</h3><p>A new visualisation of the interjoint coordination may benefit rehabilitation of stroke survivors.</p></div><div><h3>Registration</h3><p>This trial was registered at the Netherlands Trial Register (NL7535) <span>https://www.trialregister.nl/trial/7535</span><svg><path></path></svg>.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49700811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Double-Needle Gold-Silver Electrodes Continuous Glucose Monitoring Device 一种双针金银电极连续血糖监测装置
IF 4.8 4区 医学
Irbm Pub Date : 2023-06-01 DOI: 10.1016/j.irbm.2023.100752
C. Ben Ali Hassine , A. Tekin
{"title":"A Double-Needle Gold-Silver Electrodes Continuous Glucose Monitoring Device","authors":"C. Ben Ali Hassine ,&nbsp;A. Tekin","doi":"10.1016/j.irbm.2023.100752","DOIUrl":"https://doi.org/10.1016/j.irbm.2023.100752","url":null,"abstract":"<div><h3>Objectives</h3><p>Diabetes is a serious, long-term disease and the use of continuous glucose monitoring sensors can reduce reliance on other painful invasive blood testing methods such as the finger blood glucose<span> test. According to our work, a low-cost continuous glucose sensor has been developed based on electrochemical measurement techniques.</span></p></div><div><h3>Materials</h3><p><span><span>The sensor is based on a two needles system; a gold and a silver electrode are integrated into a circular shaped electronic </span>printed circuit board (PCB). The sensing part is based on biological electrochemical measurements. </span>Glucose oxidase<span> (Gox) was used as the active sensing element and ferrocene<span> (Fc) as a mediator. Simple and low-cost coating methods were used; these methods are self-assembled monolayers and deep coating. This will reduce the final cost of the sensor as no expensive technique was used. The electrical subsystem contains a low-noise and low-power trans-impedance front-end as well as a single-chip low-power Bluetooth microcontroller with a 12-bit Analog-to-Digital Converter (ADC).</span></span></p></div><div><h3>Results</h3><p>The sensor was tested in various concentrations of glucose. As a result of initial in vitro experiments, detailed analytical performance metrics are presented. The device has consistently shown a sensitivity of 3.059 mV/(mg/dl) reading with a linear range of 0-400 mg/dl.</p></div><div><h3>Conclusion</h3><p>The proposed study shows promising results for glucose detection. Thus, this type of sensor can be used for different analyzes targeting biological applications after further investigations and analysis.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49825488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CTANet: Confidence-Based Threshold Adaption Network for Semi-Supervised Segmentation of Uterine Regions from MR Images for HIFU Treatment CTANet:用于HIFU治疗的MR图像子宫区域半监督分割的基于置信度的阈值自适应网络
IF 4.8 4区 医学
Irbm Pub Date : 2023-06-01 DOI: 10.1016/j.irbm.2022.100747
C. Zhang , G. Yang , F. Li , Y. Wen , Y. Yao , H. Shu , A. Simon , J.-L. Dillenseger , J.-L. Coatrieux
{"title":"CTANet: Confidence-Based Threshold Adaption Network for Semi-Supervised Segmentation of Uterine Regions from MR Images for HIFU Treatment","authors":"C. Zhang ,&nbsp;G. Yang ,&nbsp;F. Li ,&nbsp;Y. Wen ,&nbsp;Y. Yao ,&nbsp;H. Shu ,&nbsp;A. Simon ,&nbsp;J.-L. Dillenseger ,&nbsp;J.-L. Coatrieux","doi":"10.1016/j.irbm.2022.100747","DOIUrl":"https://doi.org/10.1016/j.irbm.2022.100747","url":null,"abstract":"<div><h3>Objectives</h3><p>The accurate preoperative segmentation of the uterus and uterine fibroids from magnetic resonance images (MRI) is an essential step for diagnosis and real-time ultrasound guidance during high-intensity focused ultrasound (HIFU) surgery. Conventional supervised methods are effective techniques for image segmentation. Recently, semi-supervised segmentation approaches have been reported in the literature. One popular technique for semi-supervised methods is to use pseudo-labels to artificially annotate unlabeled data. However, many existing pseudo-label generations rely on a fixed threshold used to generate a confidence map, regardless of the proportion of unlabeled and labeled data.</p></div><div><h3>Materials and Methods</h3><p>To address this issue, we propose a novel semi-supervised framework called Confidence-based Threshold Adaptation Network (CTANet) to improve the quality of pseudo-labels. Specifically, we propose an online pseudo-labels method to automatically adjust the threshold, producing high-confident unlabeled annotations and boosting segmentation accuracy. To further improve the network's generalization to fit the diversity of different patients, we design a novel mixup strategy by regularizing the network on each layer in the decoder part and introducing a consistency regularization loss between the outputs of two sub-networks in CTANet.</p></div><div><h3>Results</h3><p>We compare our method with several state-of-the-art semi-supervised segmentation methods on the same uterine fibroids dataset containing 297 patients. The performance is evaluated by the Dice similarity coefficient, the precision, and the recall. The results show that our method outperforms other semi-supervised learning methods. Moreover, for the same training set, our method approaches the segmentation performance of a fully supervised U-Net (100% annotated data) but using 4 times less annotated data (25% annotated data, 75% unannotated data).</p></div><div><h3>Conclusion</h3><p>Experimental results are provided to illustrate the effectiveness of the proposed semi-supervised approach. The proposed method can contribute to multi-class segmentation of uterine regions from MRI for HIFU treatment.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49825493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Impact of Hepatic Iron Overload in the Evaluation of Steatosis and Fibrosis in Patients with Nonalcoholic Fatty Liver Disease Using Vibration-Controlled Transient Elastography (VCTE) and MR Imaging Techniques: A Clinical Study 应用振动控制瞬态弹性成像(VCTE)和MR成像技术评估非酒精性脂肪肝患者脂肪变性和纤维化时肝铁过载的影响:一项临床研究
IF 4.8 4区 医学
Irbm Pub Date : 2023-06-01 DOI: 10.1016/j.irbm.2022.100750
P. Pouletaut , S. Boussida , R. Ternifi , V. Miette , S. Audière , C. Fournier , L. Sandrin , F. Charleux , S.F. Bensamoun
{"title":"Impact of Hepatic Iron Overload in the Evaluation of Steatosis and Fibrosis in Patients with Nonalcoholic Fatty Liver Disease Using Vibration-Controlled Transient Elastography (VCTE) and MR Imaging Techniques: A Clinical Study","authors":"P. Pouletaut ,&nbsp;S. Boussida ,&nbsp;R. Ternifi ,&nbsp;V. Miette ,&nbsp;S. Audière ,&nbsp;C. Fournier ,&nbsp;L. Sandrin ,&nbsp;F. Charleux ,&nbsp;S.F. Bensamoun","doi":"10.1016/j.irbm.2022.100750","DOIUrl":"https://doi.org/10.1016/j.irbm.2022.100750","url":null,"abstract":"<div><h3>Purpose</h3><p><span>Three main non-invasive imaging methods are routinely used for the assessment of liver fibrosis and steatosis in patients with </span>nonalcoholic fatty liver disease<span><span><span> (NAFLD): the vibration-controlled transient elastography<span> (VCTE) using the FibroScan device, the magnetic resonance imaging (MRI) based on proton density fat fraction (PDFF), and the </span></span>magnetic resonance elastography (MRE). The purpose of our study is to evaluate the efficiency of the VCTE findings compared to the two others methods, and to analyze the impact of hepatic </span>iron overload on these comparisons.</span></p></div><div><h3>Methods</h3><p><span><span>A clinical study was performed on 94 patients with NAFLD in the radiology department of ACRIM-Polyclinic Saint-Côme (France). The study also included 17 patients with </span>hemochromatosis, measured from </span><span><math><mi>T</mi><msup><mrow><mn>2</mn></mrow><mrow><mo>⁎</mo></mrow></msup></math></span> MRI. The liver tissues of all the patients were evaluated with 1) VCTE (including the controlled attenuation (CAP) and stiffness parameters), 2) MRI (fat fraction parameter), and 3) MRE (stiffness parameter) techniques. The performance of VCTE was assessed by estimating the area under the ROC curve (AUC) for patients without or with hemochromatosis. Spearman's correlation was used for the comparison of VCTE measurements to MRI and MRE.</p></div><div><h3>Results</h3><p>VCTE-based stiffness and CAP were significantly correlated with PDFF and MRE measurements (<span><math><mi>P</mi><mo>&lt;</mo><mn>0.01</mn></math></span>) for the subgroup without hemochromatosis. The correlations failed for the subgroup with hemochromatosis.</p></div><div><h3>Conclusion</h3><p>VCTE and CAP measurements were not correlated with those from MR PDFF and MRE for patients with hemochromatosis. VCTE, PDFF and MRE modalities don't give concordant results for patients with hemochromatosis.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49825490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Five-Year Prognosis Model of Esophageal Cancer Based on Genetic Algorithm Improved Deep Neural Network 基于遗传算法改进深度神经网络的癌症五年预后模型
IF 4.8 4区 医学
Irbm Pub Date : 2023-06-01 DOI: 10.1016/j.irbm.2022.100748
J. Sun , Q. Liu , Y. Wang , L. Wang , X. Song , X. Zhao
{"title":"Five-Year Prognosis Model of Esophageal Cancer Based on Genetic Algorithm Improved Deep Neural Network","authors":"J. Sun ,&nbsp;Q. Liu ,&nbsp;Y. Wang ,&nbsp;L. Wang ,&nbsp;X. Song ,&nbsp;X. Zhao","doi":"10.1016/j.irbm.2022.100748","DOIUrl":"https://doi.org/10.1016/j.irbm.2022.100748","url":null,"abstract":"<div><h3>Objectives</h3><p><span>Esophageal cancer is a high occult malignant tumor. Even with good diagnosis and treatment, the 5-year survival rate of esophageal </span>cancer patients is still less than 30%. Considering the influence of clinical characteristics on postoperative esophageal cancer patients, the construction of a neural network model will help improve the poor prognosis of patients in the five years.</p></div><div><h3>Material and methods</h3><p><span>In this study, genetic algorithm optimized </span>deep neural network<span> is exploited to the clinical dataset of esophageal cancer. The independent prognostic factors are screened by Relief algorithm and Cox proportional risk regression. FTD prognostic staging system is established to assess the risk level of esophageal cancer patients.</span></p></div><div><h3>Results</h3><p>FTD staging system and independent prognostic factors are integrated into the genetic algorithm optimized deep neural network. The Area Under Curve (AUC) of FTD staging system is 0.802. FTD staging system is verified by the Kaplan-Meier survival curve, and the median survival time is divided for different risk grades. The FTD staging system is superior to the TNM stages in the prognosis effect. The AUC of deep neural network optimized by genetic algorithm is 0.91.</p></div><div><h3>Conclusion</h3><p>The deep neural network optimized by genetic algorithm has good performance in predicting the 5-year survival status of esophageal cancer patients. The FTD staging system has a significant prognostic effect. The FTD staging system and genetic algorithm optimized deep neural network can be successfully availed in clinical diagnosis and treatment.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49825491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Enhancing P300 Detection Using a Band-Selective Filter Bank for a Visual P300 Speller 基于带选择滤波器组的P300视觉拼写增强P300检测
IF 4.8 4区 医学
Irbm Pub Date : 2023-06-01 DOI: 10.1016/j.irbm.2022.100751
C.F. Blanco-Díaz, C.D. Guerrero-Méndez, A.F. Ruiz-Olaya
{"title":"Enhancing P300 Detection Using a Band-Selective Filter Bank for a Visual P300 Speller","authors":"C.F. Blanco-Díaz,&nbsp;C.D. Guerrero-Méndez,&nbsp;A.F. Ruiz-Olaya","doi":"10.1016/j.irbm.2022.100751","DOIUrl":"https://doi.org/10.1016/j.irbm.2022.100751","url":null,"abstract":"<div><p><strong>Background:</strong><span> An open challenge of P300-based BCI systems focuses on recognizing ERP signals using a reduced number of trials with enough classification rate.</span></p><p><strong>Methods:</strong><span> Three novel methods based on Filter Bank and Canonical Correlation Analysis (CCA) are proposed for the recognition of P300 ERPs using a reduced number of trials. The proposed methods were evaluated with two freely available EEG datasets based on 6x6 speller and were compared with five standard methods: Mean-Amplitude, Step-Wise, Principal Component Analysis, Peak, and CCA.</span></p><p><strong>Results:</strong> The proposed methods outperform significantly standard algorithms for P300 identification with a maximum AUC of 0.93 and 0.98, and an average of 0.73 and 0.76, using a single trial.</p><p><strong>Conclusion:</strong> Proposed methods based on Filter Bank are robust for the identification of P300 using a reduced number of trials, which could be used in real-time BCI spellers for rehabilitation engineering.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49864941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Impact of Scalp's Temperature on the Choice of the Best Layout for TTFields Treatment 头皮温度对TTFields治疗最佳布局选择的影响
IF 4.8 4区 医学
Irbm Pub Date : 2023-06-01 DOI: 10.1016/j.irbm.2023.100768
N. Gentilal , A. Naveh , T. Marciano , P.C. Miranda
{"title":"The Impact of Scalp's Temperature on the Choice of the Best Layout for TTFields Treatment","authors":"N. Gentilal ,&nbsp;A. Naveh ,&nbsp;T. Marciano ,&nbsp;P.C. Miranda","doi":"10.1016/j.irbm.2023.100768","DOIUrl":"https://doi.org/10.1016/j.irbm.2023.100768","url":null,"abstract":"<div><h3>Background and Objectives</h3><p><span><span>Tumor Treating Fields<span> (TTFields) is an FDA-approved technique used in the treatment of </span></span>glioblastoma<span>. It consists in applying an electric field (EF) with a frequency of 200 kHz using two pairs of transducer arrays. During treatment planning, the NovoTAL system is used to strategically place the arrays on the head in regions that maximize the EF at the tumor. Current should be injected at least 18 hours/day and induce a minimum EF of 1 V/cm at the tumor. To avoid any thermal harm to the patient, the temperature of the scalp is kept around 39.5</span></span> <!-->°C by changing the injected current. The goal of this study was to investigate how accounting for the temperature of the scalp during treatment planning might affect the choice of the best layout suggested by NovoTAL. Furthermore, we also studied the sensitivity of the results to the metric used to evaluate the layouts.</p></div><div><h3>Methods</h3><p>We used a realistic head model with a virtual glioblastoma in our studies. Through the NovoTAL system we obtained five realistic array layouts and we predicted the best one for our model based on the approach currently implemented in this system. We then repeated the same type of analysis, but also accounting for the temperature during planning. In both cases we ranked the layouts based on three different criteria: the LMiPD and the LAPD (local minimum and local average power densities, respectively) in the tumor and the SAR (specific absorption rate) in the head</p></div><div><h3>Results</h3><p>Accounting for the temperature does not significantly affect the choice of the best layout provided that the arrays are at least 1 cm apart from each other. Otherwise, a common temperature hotspot occurs in the scalp between the closest transducers of the adjacent arrays, which limits how much current can be injected and consequently treatment effectiveness. Also, the choice of the best layout depends on the criterion used.</p></div><div><h3>Conclusions</h3><p>Accounting for the temperature might led to significant variations in the current injected. The LMiPD might be used as a first criterion to choose the best treatment layout, followed by the LAPD and then the SAR.</p></div>","PeriodicalId":14605,"journal":{"name":"Irbm","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49886764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Early Detection of Pressure Ulcers: Considering the Reperfusion 早期发现压疮:考虑再灌注
IF 4.8 4区 医学
Irbm Pub Date : 2023-06-01 DOI: 10.1016/j.irbm.2023.100753
N. Gillard , A. Leong-Hoi , J.P. Departe , P. Coignard , J. Kerdraon , W. Allegre
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