Chemistry - An Asian Journal最新文献_第4页

Manipulating Intramolecular Charge Transfer in Terpyridine Derivatives towards "Turn-On" Fluorescence Chemosensors for Zn2. 操纵特吡啶衍生物的分子内电荷转移，实现 Zn2 的 "开启式 "荧光化学传感器。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-07 DOI: 10.1002/asia.202401247

Qian Zhao, Lijun Li, Dongqin Bi, Hongwei Wang, Datai Liu, Yuping Wei, Xiaojing Xing, Chunxia Yang, Dongfang Qiu, Gang Zhou

{"title":"Manipulating Intramolecular Charge Transfer in Terpyridine Derivatives towards \"Turn-On\" Fluorescence Chemosensors for Zn2.","authors":"Qian Zhao, Lijun Li, Dongqin Bi, Hongwei Wang, Datai Liu, Yuping Wei, Xiaojing Xing, Chunxia Yang, Dongfang Qiu, Gang Zhou","doi":"10.1002/asia.202401247","DOIUrl":"https://doi.org/10.1002/asia.202401247","url":null,"abstract":"A series of donor-acceptor (D-A) terpyridine derivatives with various intramolecular charge transfer interactions have been successfully synthesized bearing phenyl, methoxyphenyl, N-butyldiphenylamine (DPA), and triphenylamine (TPA) as electron-donors and terpyridine (TPY), 2,6-di(pyrazin-2-yl)pyridine (PYDPZ), and N,N-dimethylated PYDPZ (PYDPZ-2CH3) as electron acceptors. Upon the introduction of pyrazine rings instead of pyridine ones and further selective N,N'-dimethylation, the intramolecular D-A interactions are significantly enhanced, resulting in the remarkable reduced intramolecular charge transfer (ICT) transitions and quenched PL emissions in CH2Cl2 solution. However, their ICT emissions are clearly recovered upon adding Zn2+. Especially, for double positively charged compound 12, the Zn2+-induced \"turn-on\" green emission (λmax, em = 518 nm, Φ = 0.24) with excellent sensitivity (I/I0 = 77) and selectivity (IZn/ICd = 23) is detected. Under the optimized experimental condition (EtOH-H2O (9:1, v/v), containing 0.05 M HEPES buffer (pH = 7.4)), this probe is used to quantitative determination of Zn2+ in a water sample with an average recovery of 97.5%. Furthermore, the probe is applied to imaging of Zn2+ ions in HeLa cells and its mechanism is confirmed by the molecular dynamics simulation, in which lower coulomb potential for membrane surface adsorption and energy barrier for membrane translocation can be found.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401247"},"PeriodicalIF":3.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Solvent Dictated Organic Transformations. 溶剂决定的有机转化。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-07 DOI: 10.1002/asia.202400603

Tamanna Khandelia, Pritishree Panigrahi, Subhendu Ghosh, Raju Mandal, Barlina Doley, Bhisma K Patel

{"title":"Solvent Dictated Organic Transformations.","authors":"Tamanna Khandelia, Pritishree Panigrahi, Subhendu Ghosh, Raju Mandal, Barlina Doley, Bhisma K Patel","doi":"10.1002/asia.202400603","DOIUrl":"https://doi.org/10.1002/asia.202400603","url":null,"abstract":"Solvent plays an important role in many chemical reactions. The C-H activation has been one of the most powerful tools in organic synthesis. These reactions are often assisted by solvents which not only provide a medium for the chemical reactions but also facilitate reaching to the product stage. The solvent helps the reaction profile both chemically and energetically to reach the targeted product. Organic transformations via C-H activation from the solvent assistance perspective has been discussed in this review. Various solvents such as tetrahydrofuran (THF), MeCN, dichloromethane (DCM), dimethoxyethane (DME), 1,2-dichloroethane (1,2-DCE), dimethylformamide (DMF), dimethylsulfoxide (DMSO), isopropyl nitrile (iPrCN), 1,4-dioxane, AcOH, trifluoroacetic acid (TFA), Ac2O, PhCF3, chloroform (CHCl3), H2O, N-methylpyrrolidone (NMP), acetone, methyl tert-butyl ether (MTBE), toluene, p-xylene, alcohols, MeOH, 1,1,1-trifluoroethanol (TFE), 1,1,1,3,3,3-hexafluoroisopropanol (HFIP), tert-amyl alcohol and their roles are discussed. The exclusive role of the solvent in various transformations has been deliberated by highlighting the substrate scope, along with the proposed mechanisms. For easy classification, the review has been divided into three parts: (i) solvent-switched divergent C-H activation; (ii) C-H bond activation with solvent as the coupling reagent, and (iii) C-H activation with solvent caging and solvent-assisted electron donor acceptor (EDA) complex formation and autocatalysis.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400603"},"PeriodicalIF":3.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From Waste to Power: Developing Structural Supercapacitors with Red Mud and Jute Stick. 从废物到能源：用红泥和黄麻条开发结构超级电容器。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-07 DOI: 10.1002/asia.202401222

Zakaria Mohamed Nor, Fatima Omar Al-Qwairi, Abdulmajid Mirghni, Amin Al-Fakih, Shamsad Ahmad, Mohammed Al-Osta, Atif Saeed Alzahrani, Ismail M Budaiwi, Md Abdul Aziz

{"title":"From Waste to Power: Developing Structural Supercapacitors with Red Mud and Jute Stick.","authors":"Zakaria Mohamed Nor, Fatima Omar Al-Qwairi, Abdulmajid Mirghni, Amin Al-Fakih, Shamsad Ahmad, Mohammed Al-Osta, Atif Saeed Alzahrani, Ismail M Budaiwi, Md Abdul Aziz","doi":"10.1002/asia.202401222","DOIUrl":"https://doi.org/10.1002/asia.202401222","url":null,"abstract":"Developing effective, cost-efficient, and eco-friendly energy storage solutions is crucial for sustainable building structures. Red mud, a waste material, was used as the electrolyte and separator in supercapacitors, alongside activated carbon derived from jute sticks coated on steel mesh electrodes. Tests on RM-enhanced supercapacitors showed that 20% by weight of RM was the best amount. This increased the modulus of elasticity by 33%, the tensile strength by 3%, and the compressive strength by 10%. Durability was largely unaffected, with minimal additional water absorption and slight shrinkage variation. The supercapacitor cell had an extended cell potential of 1.5 V and a maximum specific capacitance of 62.3 F g-1 at 0.4 A g-1, as shown by electrochemical tests. This improved energy density to 19.5 Wh kg-1, with a power density of 301.8 W kg-1 at 0.4 A g-1 and a maximum power density of 605.8 W kg-1 at 0.8 A g-1. The cell retained 77% of its initial capacitance after 450 continuous GCD cycles, demonstrating notable stability. This stability is due to the solid electrolyte and the synergy between JC and RM, indicating promising advancements for future energy storage devices.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401222"},"PeriodicalIF":3.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Silver-Mediated Allylation of Aryl Alkenes to Synthesize 1,4-Dienes. 银介导芳基烯烃烯丙基化合成 1,4-二烯。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-07 DOI: 10.1002/asia.202401228

Dantong Wang, Jiawen Wu, Wenqian Du, Fen Zhao, Zhonghua Xia

引用次数: 0

Synthesis, structure and properties of compounds derived from Kotoite-related structures: A2MB2O6 (A = Zn, Ba, Pb; B = Pb, Ba, Zn, Cu). 钾长石相关结构衍生化合物的合成、结构和性质：A2MB2O6（A = Zn、Ba、Pb；B = Pb、Ba、Zn、Cu）。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-07 DOI: 10.1002/asia.202400868

Srinivasan Natarajan, Shreya Sasmal, Nainamalai Devarajan

引用次数: 0

Microwave Synthesis and Luminescence Efficiencies in Mixed-Ligand Europium Complexes. 混合配体铕配合物的微波合成和发光效率。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-07 DOI: 10.1002/asia.202400800

Miriam K N G Oliveira, Gerson P Castro, Simone M C Gonçalves, Alfredo M Simas

{"title":"Microwave Synthesis and Luminescence Efficiencies in Mixed-Ligand Europium Complexes.","authors":"Miriam K N G Oliveira, Gerson P Castro, Simone M C Gonçalves, Alfredo M Simas","doi":"10.1002/asia.202400800","DOIUrl":"https://doi.org/10.1002/asia.202400800","url":null,"abstract":"The microwave-assisted methodology is now extended and fine-tuned for the synthesis of mixed-ligand europium complexes with an average reaction time of 12 min. Overall, 14 different complexes were synthesized to improve luminescence using our previously proposed strategy to boost luminescence through ligand diversification, specifically by applying it to quaternary europium complexes with at least one DBM (1,3-diphenylpropane-1,3-dionate) ligand. DBM is a strong absorbant of UV radiation that can dissipate energy through nonradiative channels; thus, it is a useful molecular scaffold for sunblockers and cosmetics. Accordingly, the following luminescent tetrakis and quaternary complexes were prepared: K[Eu(DBM)4], K[Eu(β)4], K[Eu(DBM)3(β)], K[Eu(DBM)2(β)2], K[Eu(DBM)2(β)(β')], and the fully mixed complex K[Eu(DBM)(BTFA)(TTA)(HFAC)], where β can be either BTFA (4,4,4-trifluoro-1-phenylbutane-1,3-dionate), TTA (4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dionate), or HFAC (1,1,1,5,5,5-hexafluoropentane-2,4-dionate). For all the complexes, luminescence experiments were performed in chloroform and acetone solutions. Our findings confirm that mixed-ligand complexes exhibit superior quantum efficiencies compared to the average of their homoleptic counterparts. The presence of DBM in the complexes tends to dramatically increase the nonradiative decay rates of the solutions. Finally, we present formulae that provide a detailed understanding of the distinctive roles of each ligand and their relevant interactions in luminescence.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400800"},"PeriodicalIF":3.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Organic BODIPY based gels: Optical, electrochemical and self-assembly properties. 基于 BODIPY 的有机凝胶：光学、电化学和自组装特性。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-07 DOI: 10.1002/asia.202400807

Ravulakollu Srinivasa Rao, G Hanumantha Rao, Addanki Venkateswararao, Shaik Nizamuddin, Kamatham Narayanaswamy, Surya Prakash Singh

{"title":"Organic BODIPY based gels: Optical, electrochemical and self-assembly properties.","authors":"Ravulakollu Srinivasa Rao, G Hanumantha Rao, Addanki Venkateswararao, Shaik Nizamuddin, Kamatham Narayanaswamy, Surya Prakash Singh","doi":"10.1002/asia.202400807","DOIUrl":"https://doi.org/10.1002/asia.202400807","url":null,"abstract":"Two novel BODIPY dyes, BOC3 and BC12, were synthesized with variable alkyl chains at terminal amide functional units. BC12, featuring a longer alkyl chain (-C12H25), formed a gel compared to BOC3, which has a shorter alkyl chain (-CH2OCH3), due to supra molecular self-assembly in film. Both dyes exhibited absorption peaks around 530 nm in the visible region, with a red shift of about 30 nm in the film state, essential for organic electronic applications. Concentration variation studies revealed π-π stacking/aggregates in the solid state causing red shifts in absorption and emission. BC12 exhibited more significant red shifts in film compared to its solution state due to supra molecular self-assembly. Electronic structure analysis using density functional theories (BMK and O3LYP) showed better correlation with absorption using the O3LYP method. Both dyes displayed quasi-irreversible oxidation and reduction couples with suitable HOMO (5.46 eV) and LUMO (3.32 eV) energy levels for organic electronic applications. Transient photoluminescence studies indicated a longer lifetime for BC12 (5.28 ns) than BOC3 (4.50 ns), suggesting π-π aggregation and supra molecular self-assembly. BC12's gelation, attributed to its long alkyl chain and two-dimensional motifs of the BODIPY core, forms spherical-shaped nano networks.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202400807"},"PeriodicalIF":3.5,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and Synthesis of Dual Galectin-3 and EGFR Inhibitors Against Liver Fibrosis. 针对肝纤维化的双重 Galectin-3 和表皮生长因子受体抑制剂的设计与合成。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-06 DOI: 10.1002/asia.202401078

Shuanglin Liu, Fei He, Can Jin, Qing Li, Guilong Zhao, Kan Ding

{"title":"Design and Synthesis of Dual Galectin-3 and EGFR Inhibitors Against Liver Fibrosis.","authors":"Shuanglin Liu, Fei He, Can Jin, Qing Li, Guilong Zhao, Kan Ding","doi":"10.1002/asia.202401078","DOIUrl":"https://doi.org/10.1002/asia.202401078","url":null,"abstract":"Liver fibrosis, mainly arising from chronic viral or metabolic liver diseases, is a significant global health concern. There is currently only one FDA-approved drug (Resmetirom) in the market to combat liver fibrosis. Both galectin-3 and epidermal growth factor receptor (EGFR) play important roles in liver fibrosis, while galectin-3 may interact with EGFR. Galectin-3 inhibitors, typically lactose or galactose derivatives may inhibit liver fibrosis. We hypothesized that targeting both galectin-3 and EGFR may have better effect against liver fibrosis. Here, EGFR inhibitor erlotinib was used in a series of designed galectin-3 inhibitors after hybridization with the pharmacophore structure in reported galectin-3 inhibitors to impede hepatic stellate cells (HSCs) activation by a typical method of click chemistry. Bioactivity test results showed that compound 29 suppressed TGF-β-induced upregulation of fibrotic markers (α-SMA, fibronectin-1, and collagen I). The preferred compound 29 displayed better binding to galectin-3 (KD = 52.29 μM) and EGFR protein (KD = 3.31 μM) by SPR assay. Further docking studies were performed to clarify the possible binding mode of compound 29 with galectin-3 and EGFR. Taken together, these results suggested that compound 29 could be a potential dual galectin-3 and EGFR inhibitor as leading compound for anti-liver fibrosis new drug development.","PeriodicalId":145,"journal":{"name":"Chemistry - An Asian Journal","volume":" ","pages":"e202401078"},"PeriodicalIF":3.5,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142589537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

π-Conjugation as a Direct Estimate of Lewis Acidity. π-共轭作为路易斯酸度的直接估算。

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-06 DOI: 10.1002/asia.202401212

Daniel González-Pinardo, Israel Fernández

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Front Cover: Exploring the Impact of Oxygen Vacancies in Co/Pr-CeO2 Catalysts on H2 Production via the Water-Gas Shift Reaction (Chem. Asian J. 21/2024) 封面：探索 Co/Pr-CeO2 催化剂中的氧空位对通过水-气转移反应生产 H2 的影响（《亚洲化学杂志》21/2024 期）

IF 3.5 3区化学

Chemistry - An Asian Journal Pub Date : 2024-11-05 DOI: 10.1002/asia.202482101

Pallavi Saini, Paramita Koley, Devaiah Damma, Deshetti Jampaiah, Suresh K. Bhargava

引用次数: 0