Israel journal of medical sciences最新文献_第7页

Comparison of various Helicobacter pylori detection methods: serology, histology and bacteriology. 各种幽门螺杆菌检测方法的比较:血清学、组织学和细菌学。

Israel journal of medical sciences Pub Date : 1997-03-01

A Sternberg, D Coscas, Y Wagner, L Auslander, M Kaufshtein, Z Fireman

{"title":"Comparison of various Helicobacter pylori detection methods: serology, histology and bacteriology.","authors":"A Sternberg, D Coscas, Y Wagner, L Auslander, M Kaufshtein, Z Fireman","doi":"","DOIUrl":"","url":null,"abstract":"The current gold standard test for diagnosis of Helicobacter pylori involves histological staining and/or urease testing of antral biopsy specimens. However, these methods are invasive, and alternative non-invasive methods, i.e. the urease breath test and serological tests, are available. The test for H. pylori-specific serum immunoglobulin G (IgG) is now available commercially. The aim of this study was to compare the gold standard tests for diagnosis of H. pylori to the non-invasive method of detecting IgG antibody in the serum. Two hundred and twenty-five (225) subjects were tested for H. pylori by histological staining, urease testing, direct microscopy of antral biopsy specimens and quantification of serum IgG antibody. The population examined was divided into 2 groups--a group of 52 patients with no gastrointestinal symptoms and a group of 173 patients with dyspepsia. Out of 173 dyspeptic patients, 22 (12.7%) were false-positive to H. pylori. Out of 52 non-dyspeptic subjects, 30 (57.7%) were false-positive (p < 0.0001). The sensitivity and specificity were 91.6% and 51.7%, respectively. The specificity and positive predictive value increased by approximately 30% when the subjects examined were in the younger age group (< 30 years), while the sensitivity and the negative predictive value did not change significantly. This study indicates that serological testing is not recommended for diagnosis nor is it recommended for follow-up treatment, especially among the older age group (> 30 years).","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 3","pages":"160-3"},"PeriodicalIF":0.0,"publicationDate":"1997-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20253512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The lower incidence of myotonic dystrophy in Ashkenazic Jews compared to North African Jews is associated with a significantly lower number of CTG trinucleotide repeats. 与北非犹太人相比，德系犹太人肌强直性营养不良的发病率较低，这与CTG三核苷酸重复次数明显较低有关。

Israel journal of medical sciences Pub Date : 1997-03-01

R Mor-Cohen, N Magal, N Gadoth, A Achiron, T Shohat, M Shohat

引用次数: 0

Acarbose reduces blood pressure in sucrose-induced hypertension in rats. 阿卡波糖可降低蔗糖诱导高血压大鼠的血压。

Israel journal of medical sciences Pub Date : 1997-03-01

Z Madar, E C Melamed, R Zimlichman

{"title":"Acarbose reduces blood pressure in sucrose-induced hypertension in rats.","authors":"Z Madar, E C Melamed, R Zimlichman","doi":"","DOIUrl":"","url":null,"abstract":"Hypertension is often associated with impaired glucose tolerance and high insulin levels, factors that contribute to insulin resistance. The present study evaluates the effect of acarbose, a hypoglycemic drug that inhibits carbohydrate digestion in sucrose-induced hypertension in rats. The effects of diets fed to 3 groups of rats for a 16-week period were studied: sucrose + NaCl (1% wet volume [w/v]) with acarbose (0.04% wet weight [w/w]), sucrose + NaCl (1% w/v) without acarbose, and a third diet of complex carbohydrates. There was no statistical difference in the body weight between rats fed with or without acarbose. Fasting glucose levels were significantly lowered when treated with acarbose. Postprandial blood glucose and insulin levels were attenuated in rats fed sucrose + acarbose. Systolic blood pressure increased significantly (p < 0.001) in rats fed sucrose + NaCl for 3 months, whereas systolic blood pressure of acarbose-fed rats remained at the initial level. Blood pressure changes in the complex carbohydrate-fed group were lower than in rats fed sucrose. The urinary volume, Na+, and K+ of rats fed acarbose tended to increase compared to the acarbose-free diet (p < 0.05). We conclude that high insulin levels, impaired glucose tolerance and Na+ retention may contribute to the development of sucrose-induced hypertension. Acarbose prevents sucrose-induced increases in plasma glucose and insulin levels. Increases in urinary Na + may contribute indirectly to this effect with resultant normal systolic blood pressures.","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 3","pages":"153-9"},"PeriodicalIF":0.0,"publicationDate":"1997-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20252980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastric emptying in hypothyreosis. 甲状腺功能减退症的胃排空。

Israel journal of medical sciences Pub Date : 1997-03-01

G Jonderko, K Jonderko, C Marcisz, T Golab

{"title":"Gastric emptying in hypothyreosis.","authors":"G Jonderko, K Jonderko, C Marcisz, T Golab","doi":"","DOIUrl":"","url":null,"abstract":"The purpose of this study was to compare the solid phase gastric emptying (GE) in hypothyreotic patients before treatment and after euthyreosis has been reached. Ten female patients (aged 44.8 +/- 9.5[SD] y) with recently diagnosed hypothyroidism were included in the study. Their thyrometabolic state and GE were examined before treatment and after a median of 5 1/2 months (range 2 1/2-12 1/2), i.e., when euthyreosis was achieved. The control group consisted of 12 healthy women (aged 34.5 +/- 8.1y). GE of a 390-kcal 99mTc-labelled solid meal was continuously recorded under a gamma camera during 90 min. A power-exponential model was used for the analysis of the GE course. Compared to the controls, the solid phase GE of the hypothyreotics was characterized by a significantly lower curve shape parameter S (0.745 +/- 0.217 vs. 1.032 +/- 0.223, p < 0.01) and slope of the curve K (4.8 +/- 2.2 min-1.10(-3) vs. 7.6 +/- 1.3 min-1.10(-3), p < 0.01). Restoration of euthyreosis resulted in an increase of both parameters, making the GE pattern no longer statistically significantly different from that encountered in healthy subjects. The treatment did not affect the gastric half emptying time T1/2 (median: 125 min and 130 min before and after the treatment, respectively; healthy controls: 94 min). A wide variation of individual GE data was found either before or after the treatment, and in a few cases delayed GE persisted despite an effective substitutive treatment. The GE kinetics was, however, in no way related to the severity of the disease. Further research on the pathogenesis of this phenomenon is warranted.","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 3","pages":"198-203"},"PeriodicalIF":0.0,"publicationDate":"1997-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20253503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transurethral hyperthermia for relieving obstructive voiding symptoms in patients with hormone refractory prostate cancer. 经尿道热疗缓解激素难治性前列腺癌患者排尿障碍症状。

Israel journal of medical sciences Pub Date : 1997-03-01

O Nativ, Y Mor, I Leibovitch, S Halachmi, B Goldwasser

引用次数: 0

TH1/TH2 cytokine profile in celiac disease. TH1/TH2细胞因子在乳糜泻中的表达

Israel journal of medical sciences Pub Date : 1997-03-01

A Karban, A Lerner, S Shapiro

引用次数: 0

Clinical applications of fast CT scanning in cardiology. 快速CT扫描在心脏病学中的临床应用。

Israel journal of medical sciences Pub Date : 1997-03-01

J Shemesh, M Motro

引用次数: 0

Clustering of Pneumocystis carinii pneumonia in patients undergoing renal transplantation from living unrelated donors in Iraq and India. 伊拉克和印度非亲属活体肾移植患者卡氏肺囊虫肺炎聚集性研究

Israel journal of medical sciences Pub Date : 1997-03-01

N Berkman, M Glazer, M M Friedlaender, D Rubinger, J S Lafair, R Breuer, M R Kramer

{"title":"Clustering of Pneumocystis carinii pneumonia in patients undergoing renal transplantation from living unrelated donors in Iraq and India.","authors":"N Berkman, M Glazer, M M Friedlaender, D Rubinger, J S Lafair, R Breuer, M R Kramer","doi":"","DOIUrl":"","url":null,"abstract":"Over the past few years, we have observed a substantial increase in the number of patients followed at our hospital who have undergone renal transplantation from living unrelated donors (LURD). These transplants were all performed in one of two centers: Bagdad, Iraq or Bombay, India. We have observed a parallel increase in the number of cases of Pneumocystis carinii pneumonia (PCP) post-renal transplant. We conducted a ten-year retrospective analysis (1986-1995) of patients who developed PCP post-renal transplant to determine the risk factors associated with the development of this infection, with particular reference to the type of transplant and the center in which the transplant was performed. Over this period, 270 renal transplant patients were followed at this hospital and 10 episodes of PCP were documented (3.7%). Six of these cases occurred within the last 2 years, as compared to only 4 cases in the preceding 8 years. All of the cases observed in the last 2 years occurred in patients who had undergone renal transplantation from LURD in Iraq or in India. During the same period, we observed no cases of PCP in patients who had undergone transplantation in Israel (cadaver or related living donor transplants). We could find no difference between patients undergoing transplant from LURD and those undergoing other transplants in terms of immuno-suppressive therapy, frequency of organ rejection episodes or coexistent CMV infection. All patients were of Arab descent and live in the West Bank. Although we cannot identify any obvious explanation for this association, we believe that these cases represent a true cluster phenomenon. We therefore feel it is warranted for all recipients of renal transplants from living unrelated donors seen in our hospital to receive prophylactic therapy for Pneumocystis carinii pneumonia.","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 3","pages":"164-9"},"PeriodicalIF":0.0,"publicationDate":"1997-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20253513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Profile of a home hospice care unit in Israel. 以色列家庭安宁疗护单位简介。

Israel journal of medical sciences Pub Date : 1997-03-01

D Y Bonneh, P Shvartzman

引用次数: 0

Comparative study of tear substitutes and their immediate effect on the precorneal tear film. 泪液替代品的比较研究及其对角膜前泪液膜的直接影响。

Israel journal of medical sciences Pub Date : 1997-03-01

R Avisar, D Creter, H Levinsky, H Savir

引用次数: 0