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Israel journal of medical sciences最新文献

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Intracellular fluorescence polarization measurements by the Cellscan system: detection of cellular activity in autoimmune disorders. 细胞内荧光偏振测量的细胞扫描系统:检测自身免疫性疾病的细胞活性。
Israel journal of medical sciences Pub Date : 1997-04-01
N Zurgil, S Gerbat, P Langevitzh, M Tishler, M Ehrenfeld, Y Shoenfeld
{"title":"Intracellular fluorescence polarization measurements by the Cellscan system: detection of cellular activity in autoimmune disorders.","authors":"N Zurgil, S Gerbat, P Langevitzh, M Tishler, M Ehrenfeld, Y Shoenfeld","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 4","pages":"273-9"},"PeriodicalIF":0.0,"publicationDate":"1997-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20279051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intracellular IL-1 alpha in fibroblasts as a possible endogenous mediator of joint damage in rheumatoid arthritis. 成纤维细胞内IL-1 α可能是类风湿关节炎关节损伤的内源性介质。
Israel journal of medical sciences Pub Date : 1997-04-01
R N Apte
{"title":"Intracellular IL-1 alpha in fibroblasts as a possible endogenous mediator of joint damage in rheumatoid arthritis.","authors":"R N Apte","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 4","pages":"285-8"},"PeriodicalIF":0.0,"publicationDate":"1997-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20279053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex hormones and autoimmunity. 性激素和自身免疫
Israel journal of medical sciences Pub Date : 1997-04-01
A Friedman, Y Waksman
{"title":"Sex hormones and autoimmunity.","authors":"A Friedman, Y Waksman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 4","pages":"254-7"},"PeriodicalIF":0.0,"publicationDate":"1997-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20279046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti Ro/La antibodies and their clinical association. 抗Ro/La抗体及其临床相关性
Israel journal of medical sciences Pub Date : 1997-04-01
E Ben-Chetrit
{"title":"Anti Ro/La antibodies and their clinical association.","authors":"E Ben-Chetrit","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 4","pages":"251-3"},"PeriodicalIF":0.0,"publicationDate":"1997-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20279045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
beta 2-Glycoprotein I and antiphospholipid syndrome. - 2-糖蛋白I和抗磷脂综合征。
Israel journal of medical sciences Pub Date : 1997-04-01
T Koike, E Matsuura
{"title":"beta 2-Glycoprotein I and antiphospholipid syndrome.","authors":"T Koike, E Matsuura","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 4","pages":"225-38"},"PeriodicalIF":0.0,"publicationDate":"1997-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20279156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proceedings of the 10th Autoimmunity Meeting. Tel-Hashomer, Israel, 20 March 1996. 第10届自身免疫会议记录。以色列，Tel-Hashomer, 1996年3月20日。
Israel journal of medical sciences Pub Date : 1997-04-01
{"title":"Proceedings of the 10th Autoimmunity Meeting. Tel-Hashomer, Israel, 20 March 1996.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 4","pages":"223-88"},"PeriodicalIF":0.0,"publicationDate":"1997-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20338112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heparin-induced thrombocytopenia as an autoimmune disease--idiotypic evidence for the role of anti-heparin/PF4 autoantibodies. 肝素诱导的血小板减少症是一种自身免疫性疾病——抗肝素/PF4自身抗体作用的独特型证据
Israel journal of medical sciences Pub Date : 1997-04-01
Y Shoenfeld
{"title":"Heparin-induced thrombocytopenia as an autoimmune disease--idiotypic evidence for the role of anti-heparin/PF4 autoantibodies.","authors":"Y Shoenfeld","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 4","pages":"243-5"},"PeriodicalIF":0.0,"publicationDate":"1997-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20279043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Copolymer 1 from the laboratory to FDA. 共聚物1从实验室到FDA。
Israel journal of medical sciences Pub Date : 1997-04-01
D Teitelbaum, M Sela, R Arnon
{"title":"Copolymer 1 from the laboratory to FDA.","authors":"D Teitelbaum, M Sela, R Arnon","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 4","pages":"280-4"},"PeriodicalIF":0.0,"publicationDate":"1997-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20279052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implications of simultaneous tests for tuberculin and non-tuberculous mycobacteria antigen in the elderly. 老年人同时检测结核菌素和非结核分枝杆菌抗原的意义。
Israel journal of medical sciences Pub Date : 1997-03-01
Y Shachor, V Dunovets, S Poreh, C Shoham
{"title":"Implications of simultaneous tests for tuberculin and non-tuberculous mycobacteria antigen in the elderly.","authors":"Y Shachor,&nbsp;V Dunovets,&nbsp;S Poreh,&nbsp;C Shoham","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It is well established that old people living in institutions are more susceptible to tuberculous reactivation and exogenic infection than the general population. Therefore, annual screening with a tuberculin (T) skin test is suggested. Unfortunately, the specificity and sensitivity of this test is limited because of cross-reactivity with non-tuberculous mycobacteria (NTM) and anergy. We therefore investigated the possibility that a simultaneous test with NTM antigen might be helpful in the interpretation of the T test in the elderly. We tested 220 inhabitants of a geriatric institution in Israel simultaneously with T and Mycobacterium scrofulaceum sensitin (S). Ninety-six subjects reacted to the T test, and 64 of them reacted to S as well. In this last group, 38 reacted more to T, 22 more to S, and 4 reacted equally to both antigens. Of the 124 subjects who did not react to T, 24 did react to S and 123 were retested with T. Twenty-two of the latter group had a positive booster effect, but 9 of the positive booster responders initially reacted to S. The difference between the proportions of the positive booster effect in the responders and the non-responders to S was significant. We conclude that in an area where infection with NTM is present a simultaneous S test may clarify the meanings of initial and booster-positive responses to T in the elderly, as well as exclude anergy when the T test is negative.</p>","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 3","pages":"170-4"},"PeriodicalIF":0.0,"publicationDate":"1997-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20253514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gastrin levels in colorectal cancer. 结直肠癌中的胃泌素水平。
Israel journal of medical sciences Pub Date : 1997-03-01
Y Niv, N Heizelracht, S A Lamprecht, A D Sperber, G M Fraser, B Schwartz
{"title":"Gastrin levels in colorectal cancer.","authors":"Y Niv,&nbsp;N Heizelracht,&nbsp;S A Lamprecht,&nbsp;A D Sperber,&nbsp;G M Fraser,&nbsp;B Schwartz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Our objective was to determine whether colorectal cancer tissue synthesizes and secretes biologically active gastrins resulting in a rise of gastrin levels in patients with adenocarcinoma of the colon. Blood samples for gastrin determination were taken from the artery feeding, and from the vein draining colon tumors, from a vein draining an uninvolved colon segment and from a peripheral vein. Tissue gastrin levels were measured in tumor tissues and normal mucosa taken by colonoscopic biopsy from colon cancer patients and healthy controls. The setting was a university hospital research laboratory. We had seventeen patients with colorectal cancer and 23 controls. No significant difference was found in peripheral venous blood gastrin levels between the cancer and the control groups. Serum gastrin concentration was not significantly different in the arterial blood which supplied the tumor area, the venous blood draining the tumor, the \"uninvolved\" mucosa or the control normal epithelium. Cancer tissue gastrin levels were lower than those measured in biopsies of uninvolved mucosa from cancer patients and normal controls. The present results show no rise of gastrin blood levels in patients with colon cancer, nor any evidence of gastrin-increased synthesis by the tumors.</p>","PeriodicalId":14590,"journal":{"name":"Israel journal of medical sciences","volume":"33 3","pages":"186-9"},"PeriodicalIF":0.0,"publicationDate":"1997-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20253517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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