Iranian Journal of Neonatology IJN最新文献_第7页

Infantile Herpes Simplex Virus Meningitis: A Case Report 婴儿单纯疱疹病毒性脑膜炎1例报告

Iranian Journal of Neonatology IJN Pub Date : 2021-01-01 DOI: 10.22038/IJN.2020.49825.1879

E. Khodashenas, R. Saeidi, N. Ghasemi

{"title":"Infantile Herpes Simplex Virus Meningitis: A Case Report","authors":"E. Khodashenas, R. Saeidi, N. Ghasemi","doi":"10.22038/IJN.2020.49825.1879","DOIUrl":"https://doi.org/10.22038/IJN.2020.49825.1879","url":null,"abstract":"Background: Herpes simplex virus (HSV) is one of the main causes of neonatal meningitis; nonetheless, it usually goes unreported. A lumbar puncture is needed to accurately differentiate between viral and bacterial meningitis. The cerebrospinal fluid can be analyzed to exclude bacterial meningitis; nevertheless, the identification of the specific viral cause may be beneficial. Viral diagnosis determines prognosis, improves the care of the patient, decreases hospitalization duration, and reduces unnecessary use of antibiotics. In young infants, the herpes simplex virus infection is responsible for serious complications leading to morbidity, mortality, and permanent sequelae in survivors. The clinical findings of this infection usually include tremors, seizures, lethargy, irritability, poor feeding, temperature instability, and a bulging anterior fontanel, which are common in almost all forms of meningitis. These similarities make the differential diagnosis rather difficult. Case report: We report and discuss the case of an an11-day-old neonate girl who presented with fever and negative test results, as well as our challenges that finally led to the diagnosis of HSV-related meningitis and its management. Conclusion: It could be managed to reach a firm diagnosis confirming the initial differential diagnosis through additional and repetitive testing. Therefore, it is concluded that clinical judgments may be more reliable than paraclinical results in the individual approach for each patient. Furthermore, HSV infection should also be considered for patients with a persistent fever of unknown origin. It is also recommended to adopt separate procedures for the suspicion of HSV type 1 and HSV type 2. Keywords: Herpes simplex virus, Infantile fever, Meningitis","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"35 1","pages":"89-95"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73355062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparative Study between Postextubation of Preterm Infants into High-Flow Nasal Cannulae versus Nasal Continuous Positive Airway Pressure 早产儿拔管后高流量鼻插管与鼻持续气道正压通气的比较研究

Iranian Journal of Neonatology IJN Pub Date : 2020-11-22 DOI: 10.22038/IJN.2020.43810.1753

Ramy Saleh Morsy, Magda Mahmoud Sedky, R. Said, Aliaa A Ali, W. Abuelhamd

{"title":"A Comparative Study between Postextubation of Preterm Infants into High-Flow Nasal Cannulae versus Nasal Continuous Positive Airway Pressure","authors":"Ramy Saleh Morsy, Magda Mahmoud Sedky, R. Said, Aliaa A Ali, W. Abuelhamd","doi":"10.22038/IJN.2020.43810.1753","DOIUrl":"https://doi.org/10.22038/IJN.2020.43810.1753","url":null,"abstract":"Background and Aim of work: To support breathing of premature infants, there has been a trend toward less tracheal intubation, less mechanical ventilation, and more nasal respiratory support which can result in the improvement of successful extubation rate. The two types of nasal respiratory support after extubation, which are most known, are the nasal CPAP and High flow nasal cannula. The objective of current study is to investigate and compare successful extubation by using high-flow nasal cannulae (HFNC) versus conventional NCPAP after a period of endotracheal positive pressure ventilation. Patients and methods: This prospective study was conducted in the NICU of Gynecology and Obstetrics department of Kasr El Aini hospital on 210 preterm infants. Post extubation failure rates were compared between both groups (HFNC) and (NCPAP). The collected data were analyzed by SPSS program version 20.Results: Neonates who needed reintubation within 72 hour after initial extubation were higher in HFNC group (72.7%) versus (27.3%) in CPAP group (P-value 0.063) and (45.8%) of neonates in HFNC group needed re-intubation within one week of initial extubation versus (54.2%) in CPAP (P-value 0.970). Mean duration of respiratory support using HFNC was 3.7 days compared with 6.5 days using CPAP (p-value 0.001). Among neonates who suffered nasal trauma 90.6% of infants belong to CPAP group 12.5% while 9.4% belong to HFNC group (p-value 0.001). Conclusion: The use of CPAP and HFNC after extubation of preterm mechanically ventilated neonates was statistically equal regarding extubation failure.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82703263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asphyxia effects on colony forming ability of hematopoietic stem cell of cord blood 窒息对脐带血造血干细胞集落形成能力的影响

Iranian Journal of Neonatology IJN Pub Date : 2020-11-22 DOI: 10.22038/IJN.2020.39688.1631

A. Shahfarhat, Abolfazl Nosrati Tirkani, Dariyush Hamidi Alamdari, محمدحسن ارجمند

{"title":"Asphyxia effects on colony forming ability of hematopoietic stem cell of cord blood","authors":"A. Shahfarhat, Abolfazl Nosrati Tirkani, Dariyush Hamidi Alamdari, محمدحسن ارجمند","doi":"10.22038/IJN.2020.39688.1631","DOIUrl":"https://doi.org/10.22038/IJN.2020.39688.1631","url":null,"abstract":"Background:Asphyxia is the medical situation resulting of deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm usually to the brain. Human umbilical cord blood (UCB) is a well-established source of hematopoietic stem/progenitor cells (HSPCs) for allogeneic stem cell transplantation. Low level of O2 in infants with asphyxia during labor can influence on proliferation and differentiation of stem cells in cord blood. Method:The quality and colony forming unit of hematopoietic stem cells in cord blood of infants with severe asphyxia with Apgar score 3-5or need to cardiac pulmonary resuscitation five minutes after delivery were compared with the normal group with normal Apgar score.Afterward, hematopoietic stem cells were isolated and cells were cultured in enrichedmedia (MethoCult H4435) special for HSPCs for 7 days to assessment growth and colony formation. Results: There was a significant difference in the number of RBC (P=0.0016) and WBC precursor’s colonies (P = 0.006), in plate with 104 cord blood hematopoietic stem cells in infants who exposed to hypoxemia during labor.Conclusion: Umbilical cord blood is valued for its content of stem cells.Severehypoxia in the perinatal period does not have negative influence on viability of UCB hematopoietic stem cells to growth and formation colonies.Based on our research transient severe asphyxia does not have negative effects on HSPCs to save and banking for likely problems in future","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78355726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The maternal and neonatal characteristics of hyperbilirubinemia in need of exchange transfusion 需要换血的高胆红素血症的产妇和新生儿特征

Iranian Journal of Neonatology IJN Pub Date : 2020-10-05 DOI: 10.22038/IJN.2020.47630.1814

H. Boskabadi, G. Maamouri, N. Behgam

{"title":"The maternal and neonatal characteristics of hyperbilirubinemia in need of exchange transfusion","authors":"H. Boskabadi, G. Maamouri, N. Behgam","doi":"10.22038/IJN.2020.47630.1814","DOIUrl":"https://doi.org/10.22038/IJN.2020.47630.1814","url":null,"abstract":"Background: Excessive hyperbilirubinemia is potentially neurotoxic and can lead to long-term complications in neonates. Exchange transfusion (ECT) is one of the important treatments for hyperbilirubinemia. The main goal of this study is to determine the maternal and neonatal characteristics of hyperbilirubinemia in infants in need of exchange transfusion.Methods and materials: This cross-sectional study was performed on 380 infants over 35 gestational weeks, 2 to 14 days old, with bilirubin above 17 mg/dl who had undergone ECT at Ghaem Hospital of Mashhad from 2010 to 2020. In this study, neonates in need of ECT were selected using available sampling method. The checklist form was designed based on neonatal examination, maternal (maternal age, parity), and neonatal status (age, sex, weight) and serial laboratory tests before and after ECT (total bilirubin, hematocrit, and platelet). Then, these variables were compared based on the cause of hyperbilirubinemia.Results: The mean bilirubin serum level was 28.5 mg/dl in male and 26.5 mg/dl (P = 0.096) in female infants, 29.5 mg/dl in the C-section and 28.1 mg/dl (P = 0.458) in normal vaginal delivery. Sixty percent of the neonates suffered from weight loss and 22% had more than 3% daily weight loss. In our study, infants first presented RH incompatibility and then ABO incompatibility and finally G6PD deficient neonates.Conclusion: Overall, these finding suggest that normal vaginal delivery, repeated breastfeeding, prevention of severe weight loss, early detection of RH & ABO incompatibility and G6PD deficiency, as well as appropriate management of hyperbilirubinemia may reduce both the need for ECT and alleviate complications of neonatal hyperbilirubinemia.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"57 9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83675890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fiberoptic Bronchoscopy as a Diagnostic Tool in NICU: A Single Center Experience 纤维支气管镜作为NICU的诊断工具:单中心经验

Iranian Journal of Neonatology IJN Pub Date : 2020-10-05 DOI: 10.22038/IJN.2020.45914.1768

M. Moslehi, F. Fallahi

{"title":"Fiberoptic Bronchoscopy as a Diagnostic Tool in NICU: A Single Center Experience","authors":"M. Moslehi, F. Fallahi","doi":"10.22038/IJN.2020.45914.1768","DOIUrl":"https://doi.org/10.22038/IJN.2020.45914.1768","url":null,"abstract":"Objective: Respiratory disorders are an important cause of morbidity and mortality in neonates. Fiberoptic Bronchoscopy (FOB) is being increasingly used by pediatricians both for diagnostic and therapeutic indications in children. However, information on diagnostic utility and safety of FOB in neonates is limited. FOB remains relatively under-used in the care of neonates. This article provides a practical overview of the wide diagnostic aspects of the FOB in infants who are hospitalized in Neonatal Intensive Care Unit (NICU). Frequencies of common indications, their findings, and highlights contribute to quick managing of those neonates with respiratory disorders.Patients and Methods: This descriptive study was conducted in the NICU of Namazi hospital and included 150 neonates with various respiratory problems admitted over a 5-year period, from 2013 till 2018. All subjects underwent FOB and bronchoalveolar Lavage (BAL), using a bronchoscope of 2.8 (EVIS EXERA III Olympus bronchoscope).Results: The greatest indications for doing FOB were hyper Secretion in 138 (92%), prolonged mechanical ventilation in 108 (72%) and persistent radiological finding in 97 (64.6%). Bronchoscopy detected various airways anomalies such as Laryngomalacia (72%), Tracheobronchomalacia (64%), subglottic stenosis (26%), vocal cord paresis (18%), tracheoesophageal fistula (6.7%), laryngeal cleft (6%) and laryngeal web (4%). BAL results showed that the cultures were positive in 13.33% (20) of neonates. Acinetobacter was the most commonly reported bacterial infection, observed in 8% of neonates.Conclusions: Findings of this study demonstrate that FOB, when performed by an experienced and well-trained person and in an environment with appropriate facilities, can be a safe and useful tool for the early diagnosis of many of the airway disorders among neonates who are admitted in NICUs.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73752629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of QT interval in neonates with maternal gestational diabetes and healthy mothers 妊娠期糖尿病与健康母亲新生儿QT间期的比较

Iranian Journal of Neonatology IJN Pub Date : 2020-10-05 DOI: 10.22038/IJN.2020.47725.1816

E. Alaee, Maryam Koochaki, M. Besharat, Hassan Esmaeili

{"title":"Comparison of QT interval in neonates with maternal gestational diabetes and healthy mothers","authors":"E. Alaee, Maryam Koochaki, M. Besharat, Hassan Esmaeili","doi":"10.22038/IJN.2020.47725.1816","DOIUrl":"https://doi.org/10.22038/IJN.2020.47725.1816","url":null,"abstract":"Background: The risk of developing metabolic syndrome and diseases as Diabetes mellitus have been raised as worldwide rise of obesity. Gestational diabetes (GDM) or maternal hyperglycemia is a risk factor for cardiac dysfunction in neonates. The present study compared QT interval in neonates with maternal gestational diabetes and healthy mothers.Patients and Methods: In this case-control study, term neonates with maternal GDM (case group, N = 42) and those with healthy non-diabetic mothers (control group, N=42) have been included from March 2016 to February 2017, in Sayyad-e-Shirazi hospital, Gorgan, Northeast of Iran. A pediatric cardiologist evaluated septal hypertrophy by Doppler echocardiography (Zonare ZS3) during first two weeks after birth. A standard 12-lead electrocardiogram was recorded for 10 seconds and corrected QT (QTc) value was calculated. Data were analyzed in latest version of SPSS using Chi-square and t-test to evaluate the differences in QT values and other indices between two groups. P-values less than 0.05 were considered statistically significant.Results: The present study showed congenital heart diseases in 6 neonates. Significantly higher QT (249±36 vs. 245± 28 ms) and septal thickness (6.09±1.07 vs. 5± 1 mm) and lower QTc value (382±44.06 vs. 392± 34 ms) were seen in case group compared to controls (P","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74269556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of Perineal Ultrasound in Differentiating Paraurethral Cysts in Newborns 会阴超声在新生儿尿道旁囊肿鉴别中的作用

Iranian Journal of Neonatology IJN Pub Date : 2020-10-01 DOI: 10.22038/IJN.2020.40780.1666

M. M. Rashed, Mona Maftouh, Seyyed Ali Alamdaran, Moloud Moghaddasi

引用次数: 0

Levetiracetam as the First-line Antiepileptic in Neonatal Seizures 左乙拉西坦作为新生儿癫痫发作的一线抗癫痫药物

Iranian Journal of Neonatology IJN Pub Date : 2020-10-01 DOI: 10.22038/IJN.2020.47926.1822

Harikrishnan Ramachandran, Jayashree Purkayastha, L. Lewis, Ramesh Bhat Yellanthoor, Apurv Barche, Sneha J. Andrade

{"title":"Levetiracetam as the First-line Antiepileptic in Neonatal Seizures","authors":"Harikrishnan Ramachandran, Jayashree Purkayastha, L. Lewis, Ramesh Bhat Yellanthoor, Apurv Barche, Sneha J. Andrade","doi":"10.22038/IJN.2020.47926.1822","DOIUrl":"https://doi.org/10.22038/IJN.2020.47926.1822","url":null,"abstract":"Background: The quest persists for an ideal newer antiepileptic drug (AED) with better efficacy and tolerability. Levetiracetam (LEV) is one of these AEDs with a novel mechanism of action, good pharmacokinetic profile, acceptable tolerability, and side-effect profile. The present study assessed the safety and efficacy of intravenous levetiracetam as a first-line AED in neonatal seizures.Methods: This prospective observational study was conducted on all term neonates with seizures admitted to the Neonatal Intensive Care Unit (NICU) of a tertiary care center. Neonates with hypoglycemia, hypocalcemia, hypomagnesemia, inborn errors of metabolism, or those who received other AEDs prior to admission were excluded from the study. 20mg/kg Intravenous LEV was administered as first-line AED and graded up to 40mg/kg if seizures were not controlled in 2 h; thereafter, second-line AED was added.Results: Only 36.2% (21/58) of the cases responded to LEV as first-line AED. Hypoxic Ischaemic Encephalopathy(HIE) was the most common etiology of seizures (55.2%). Subtle seizures were most responsive to LEV (60%), while multifocal clonic seizures (22.3%) responded the least. No adverse effect of LEV was observed during the study period.Conclusion: Only 36.2% of the cases responded to LEV as first-line AED, and subtle seizures were the most responsive seizures. Therefore, the efficacy of LEV as first-line AED in neonatal seizures is yet to be proven by a larger study. There were no adverse effects of LEV during the study period indicating the relative safety of this drug.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"76 1","pages":"39-45"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86318860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing Family-Centered Care in Iranian NICUs from Perspective of Neonatal Individual Developmental Care 从新生儿个体发展护理的角度评估伊朗新生儿重症监护病房的家庭中心护理

Iranian Journal of Neonatology IJN Pub Date : 2020-10-01 DOI: 10.22038/IJN.2020.47189.1808

Z. Eskandari, F. Akrami, Mostajab Razavi Nejad, A. Almasi-Hashiani, M. Heidarzadeh

{"title":"Assessing Family-Centered Care in Iranian NICUs from Perspective of Neonatal Individual Developmental Care","authors":"Z. Eskandari, F. Akrami, Mostajab Razavi Nejad, A. Almasi-Hashiani, M. Heidarzadeh","doi":"10.22038/IJN.2020.47189.1808","DOIUrl":"https://doi.org/10.22038/IJN.2020.47189.1808","url":null,"abstract":"Background: Preterm deliveries and premature babies are among challenges for families and communities. A family-centered care model is a model that helps families become less challenged by preterm birth and learn how to care for their premature infants. The aim of this study was to evaluate the implementation of family-centered care in the Iranian neonatal intensive care units (NICUs).Methods: This national cross-sectional study was conducted on a total of 23 NICUs of 9 universities of medical sciences, where students were trained in the neonatology fellowship course, in seven provinces of Iran. Family-centered developmental care was assessed in six different domains, including the philosophy of nursery, family communication, family support, family resources, admission and discharge planning, and decision-making. In addition, a total of 29 items were asked. The data were analyzed using Stata software (version 13) using descriptive statistical tests.Results: The mean scores in all domains were weak, and the total score for all domains was 34.18 (95% CI: 33.75-34.60) out of 100. The mean scores were 30 in the philosophy of nursery, 43.47 in family communication, 26.71 in family support, 35 in family resources, 45 in admission and discharge planning, and 25 in decision-making. The lowest score was reported for decision-making, and the highest score was reported for admission and discharge planning.Conclusion: Since family-centered developmental care in Iran is not favorable, the obtained findings suggest the development of a suitable plan to upgrade family-centered developmental care as well as comprehensive NICU care, including developmental care, with regard to other domains.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"35 1","pages":"87-92"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89402010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Peritoneal Dialysis in Neonates: A Five-Year Experience 新生儿腹膜透析:五年经验

Iranian Journal of Neonatology IJN Pub Date : 2020-10-01 DOI: 10.22038/IJN.2020.44569.1738

M. Kadivar, Razieh Sangsari, K. Mirnia, Arash Abbasi, Motahareh Rabipour

{"title":"Peritoneal Dialysis in Neonates: A Five-Year Experience","authors":"M. Kadivar, Razieh Sangsari, K. Mirnia, Arash Abbasi, Motahareh Rabipour","doi":"10.22038/IJN.2020.44569.1738","DOIUrl":"https://doi.org/10.22038/IJN.2020.44569.1738","url":null,"abstract":"Background: Peritoneal dialysis is an applicable method for children and even neonates. Moreover, it allows the quiet excretion of fluid and soluble substances without hemodynamic instability. Peritoneal dialysis can be continued easily in hospitalized infants. However, the question is whether peritoneal dialysis is an effective procedure to replace hemodialysis in neonates or not?Methods: The population of this study included all neonates who were admitted to the Neonatal Intensive Care Unit of Children's Medical Center Hospital, Tehran, Iran, and underwent peritoneal dialysis during 2012-17. The data were collected using a questionnaire. Subsequently, the underlying diseases, complications, and laboratory changes were determined before and after peritoneal dialysis.Results: In total, 29neonates who underwent peritoneal dialysis were evaluated in this study. Peritoneal dialysis was performed on 58.6% and 41.4 % of the cases for congenital metabolic disorder and extra body fluids, respectively. Moreover, electrolyte disorders and uremia were observed in 13.7% and 13.8% of the total cases, respectively. Several indications were seen in some infants. Dialysis failure was seen in 79.3% of the cases, most of which were due to dialysis catheter obstruction; however, the mean changes in potassium, sodium, urea, creatinine, acidosis, ammonia, and phosphorus were significant72 h after dialysis.Conclusion: This study showed that peritoneal dialysis faced several failures in newborns; however, metabolic disorders, electrolyte imbalance, uremia, and extra body fluid were resolved. Moreover, it is considered a vital and effective way for the treatment of newborns, especially in low-resource countries in which hemodialysis cannot be performed easily.","PeriodicalId":14584,"journal":{"name":"Iranian Journal of Neonatology IJN","volume":"2 1","pages":"64-68"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87237546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0