IOSR Journal of Pharmacy最新文献_第8页

Characterization of Enterococcus species in a tertiary care hospital 某三级医院肠球菌种类特征分析

IOSR Journal of Pharmacy Pub Date : 2016-08-01 DOI: 10.9790/3013-068014851

S. Nautiyal, S. Jauhari, G. Joshi, V. Kataria

引用次数: 3

Statistical optimization of bioactive metabolite production from Bacillus cereus NSD 10072 by using low cost substrate 利用低成本底物生产蜡样芽孢杆菌NSD 10072生物活性代谢物的统计优化

IOSR Journal of Pharmacy Pub Date : 2016-08-01 DOI: 10.9790/3013-068020815

Namita Singh, Rajneesh Jaryal, S. Shweta, A. Devi, S. Panchal, P. Thakur

引用次数: 0

Blindness and ocular posterior segment involvement in the acute phase of Kawasaki disease: a mini-review 川崎病急性期的失明和眼后段受累:一个小型回顾

IOSR Journal of Pharmacy Pub Date : 2016-08-01 DOI: 10.9790/3013-068012629

T. Nakad

{"title":"Blindness and ocular posterior segment involvement in the acute phase of Kawasaki disease: a mini-review","authors":"T. Nakad","doi":"10.9790/3013-068012629","DOIUrl":"https://doi.org/10.9790/3013-068012629","url":null,"abstract":"Ocular involvement in the acute phase of Kawasaki disease typically involves the anterior segment of the eye, and its associated treatment outcomes are generally excellent. However, there are rare reports of posterior segment involvement, and these are associated with poorer outcomes. This study reviewed six patients with recently reported blindness and/or ocular posterior segment involvement in the acute phase of Kawasaki disease. The median age of these patients was 8.5 years old (range: 6–12 years old). The ocular symptoms were photophobia, reduction of vision, blindness, and ocular pain. Five patients exhibited optic disc involvement and three patients showed retinal vessel involvement. All patients received intravenous immunoglobulin therapy and two patients received systemic corticosteroid administration. The visual acuity outcomes of treatment were excellent in five of the patients. However, in one patient there was still no light perception in the affected eye at two months after the initial onset of the disease. This was associated with the possible obstruction of the ophthalmic artery due to vasculitis. Older children may have a higher associated risk of blindness and ocular posterior segment involvement in the acute phase of Kawasaki disease.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"180 1","pages":"26-29"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78020995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Medicinal plants with central nervous effects (part 2): plant based review 具有中枢神经作用的药用植物(第二部分):植物综述

IOSR Journal of Pharmacy Pub Date : 2016-08-01 DOI: 10.9790/3013-068015275

A. Al-Snafi

引用次数: 36

Traumatic Posterior Hip Dislocation In A 9 Year Child: A Case Report 9岁儿童外伤性髋后脱位1例

IOSR Journal of Pharmacy Pub Date : 2016-01-01 DOI: 10.9790/3013-06712326

Khandge Av

引用次数: 0

Amary llidaceae Perspectives In Alzheimer´S Disease 苦参科在阿尔茨海默病中的研究进展

IOSR Journal of Pharmacy Pub Date : 2016-01-01 DOI: 10.9790/3013-06712733

W. O. Castillo

{"title":"Amary llidaceae Perspectives In Alzheimer´S Disease","authors":"W. O. Castillo","doi":"10.9790/3013-06712733","DOIUrl":"https://doi.org/10.9790/3013-06712733","url":null,"abstract":"Alzheimer ́s disease (AD) is the most prominent type of dementia in elderly population. The etiology is multifactorial, and pathophysiology of disease is complex with slowly progressive and irreversible deterioration. Traditionally, AD researches have focused on the pathogenesis caused by Neuritic Plaques (NPs) and Neurofibrilary Tangles (NFTs); however, in the pathologic spectrum of disease, there are others independent pathways involved. Although several genetic alterations have been associated with AD, as memory as AD seem to be influenced by genetic, physiologic and environmental factors, resulted of accumulate over time. The current therapeutic approaches for AD temporarily improve the symptoms; and despite intensive efforts, none of the treatments available today alter the course of disease. Nevertheless, one of the most promising approaches for treating it is to enhance acetylcholine level and decrease oxidative stress in brain of AD patients. In line with this, different studies indicate that the alkaloids belonging to Amaryllidaceae family exhibit a wide range of biological activities. Galantamine has become the most attractive of alkaloids for its use in the treatment of AD; however, Amaryllidaceaes contain other alkaloids which have high potential as acetylcholinesterase inhibitors (ACHEI) and antioxidant.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"119 ","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91459983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study Of Prevalence Of Pulmonary Hypertension In Chronic Kidney Disease And Its Co-Relation With Clinical & Biochemical Parameters. 慢性肾脏病患者肺动脉高压患病率及其与临床生化指标相关性的研究

IOSR Journal of Pharmacy Pub Date : 2016-01-01 DOI: 10.9790/3013-06711822

Dr.Neelam Redkar

{"title":"Study Of Prevalence Of Pulmonary Hypertension In Chronic Kidney Disease And Its Co-Relation With Clinical & Biochemical Parameters.","authors":"Dr.Neelam Redkar","doi":"10.9790/3013-06711822","DOIUrl":"https://doi.org/10.9790/3013-06711822","url":null,"abstract":"-OBJECTIVES: The objectives of this prospective observational study were to study (i) the prevalence of pulmonary hypertension (PH) in patients who are on conservative management, haemodialysis or continuous ambulatory peritoneal dialysis, (ii) the co-relation of PH with variables such as A-V fistula, hypertension, diabetes Mellitus & duration for dialysis, and (iii) the co-relation of PH with biochemical parameters.MATERIALS AND METHODS: The study was conducted in a tertiary care centre in Mumbai over a period 12 months after obtaining approval from the Institutional Ethics Committee. 245 CKD patients, on conservative management, haemodialysis and continuous ambulatory peritoneal dialysis were enrolled in this study, taking into consideration the inclusion & exclusion criteria and appropriate informed consent after taking detailed history of every patient. All patients underwent routine investigations and 2D ECHO for pulmonary hypertension. RESULTS: Our study enrolled 245 patients in the age group of 20 to 85 years where 68.6% patients were male and 31.4% were females. 28.2% patients had CKD with PH while 71.8% had CKD without PH. The proportion of patients with PH having AV fistula was significantly more than those without AV fistula. Of the 28.2% patients with PH, 33.6% had hypertension and 22% were diabetic. Our study revealed a positive association between the duration of dialysis and the prevalence of PH along-with low levels of haemoglobin and serum bicarbonate, and high levels of uric acid, BUN and creatinine. CONCLUSION: The prevalence of PH was found to be 28.2%. PH is positively correlated with chemical as well as biochemical parameters.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"4 1","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87447248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quinoxaline as a potent heterocyclic moiety 喹啉作为一个强效的杂环片段

IOSR Journal of Pharmacy Pub Date : 2014-12-05 DOI: 10.9790/3013-040120101617027

S. Srivastava, J. Banerjee, Nomi Srestha

引用次数: 9

A review on chemistry and biological significance of benzimidaole nucleus 苯并咪唑核的化学和生物学意义综述

IOSR Journal of Pharmacy Pub Date : 2014-12-05 DOI: 10.6084/M9.FIGSHARE.1294838.V1

Phr Iosr, S. Nomi

引用次数: 13

Uveitis: Pathogenesis, Clinical presentations and Treatment 葡萄膜炎:发病机制、临床表现及治疗

IOSR Journal of Pharmacy Pub Date : 2014-12-05 DOI: 10.6084/M9.FIGSHARE.1294836.V1

Phr Iosr, Mustafa P.Muthusamy Ss. Hussain SC.Shimmi MM.Sein Murtaza

引用次数: 15