IOSR Journal of Pharmacy最新文献

Antibiotic Utilization Pattern in Surgery and Pediatric, Bhagwan Mahaveer Jain Hospital, Bangalore, India 外科和儿科抗生素使用模式，Bhagwan Mahaveer Jain医院，班加罗尔，印度

IOSR Journal of Pharmacy Pub Date : 2017-07-01 DOI: 10.9790/3013-0707010610

M. Soleimani

{"title":"Antibiotic Utilization Pattern in Surgery and Pediatric, Bhagwan Mahaveer Jain Hospital, Bangalore, India","authors":"M. Soleimani","doi":"10.9790/3013-0707010610","DOIUrl":"https://doi.org/10.9790/3013-0707010610","url":null,"abstract":"Objective: To assess antibiotic utilization pattern in surgery and pediatric and to explore reasons for the nonadherence. Methods: A prospective clinical record review was done on 180 patients admitted in the Medicine, Surgery, and Paediatrics. The antibiotic prescription will be assessed whether it is according to hospital antibiotic policy and in case of violation the reason for it will be noted down. The incidence and cause for the nosocomial infection will be noted down. Apart from these antibiotic categories, cost of antibiotic therapy from medical bills and the cost for the antibiotics will be calculated. Results: In our study population out of 180 patients 110 were male and 70 were female and in paediatric population16% were male and 1 3.5%. In surgery department highest number i.e. 12.5% male and 9.5% females are in the age group 31-40 years. 2% males and 2.5% females were in the age Group of 81-90. Various classes of antibiotics like penicillin’s, macrolides, cephalosporin’s and fluoroquinolones were prescribed. of which13% males, 7% females were prescribed with penicillin’s which were highest among monotherapy. Among combination therapy 14% of males were prescribed and 7 % females with penicillin which were highest. There were various combination drugs prescribed which are specific to the disease out of which ampicillin+gentamicin+metronidazole (5%) and ampicillin+gentamicin+cefotaxime+amikacin (5%). Conclusion: In appropriate use of antibiotics is detected due to lack of culture sensitivity test which has to make mandatory in the hospital before antibiotic prescription. Less cost effective antibiotic treatment should be prescribed. Polypharmacy was seen in a large extent were patients were put on 4-5 antibiotics which has to be avoided by using broad spectrum antibiotics and fixed dose antibiotics suitably. The drug interactions with antibiotics should be also minimized.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"35 1","pages":"06-10"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73518863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on Utilization Pattern of Pulmonary Inhalers in Inpatient, Bhagwan Mahaveer Jain Hospital, Bangalore, India 住院病人肺部吸入器使用模式的研究，巴格万马哈维尔耆那医院，班加罗尔，印度

IOSR Journal of Pharmacy Pub Date : 2017-07-01 DOI: 10.9790/3013-0707010105

Shivah Karamian

{"title":"Study on Utilization Pattern of Pulmonary Inhalers in Inpatient, Bhagwan Mahaveer Jain Hospital, Bangalore, India","authors":"Shivah Karamian","doi":"10.9790/3013-0707010105","DOIUrl":"https://doi.org/10.9790/3013-0707010105","url":null,"abstract":"Objective: To study on utilization pattern of pulmonary inhalers in inpatient, Bhagwan Mahaveer Jain Hospital, Bangalore, India. Methods: The proper inhalation technique was assed using the questionnaires there were 11 steps for MDI and 12 steps for MDI + spacer each correct technique carried a score of 1 and wrong technic carried 0.The adherence to the inhaler technique was assed using the formula correct dose/incorrect dose*100 and the reasons for non-adherence was also noted. The therapeutic inappropriateness of prescribed inhalers and antiasthmatic drugs is determined with standard guidelines. The cost involved in use of inhalers in therapeutic inappropriateness also considered. Results: In our study population about 10.8% asthmatics and 20% COPD patients were prescribed with budesonide MDI. About 10% asthmatics and 9.1 COPD patients were prescribed with budesonide MDI+spacer. About 4.1% asthmatics and 2.5% coped patients were prescribed with salbutamol MDI. About 17% asthmatics and 10% copd patients were prescribed with mdi ipratropium and 8% asthmatics and 12.5% coped patients were prescribed with ipratropium MDI+spacer. When the knowledge regarding the usage of inhalers was assed using standard questionnaire which had 11 steps for MDI and 12 steps for MDI+spacer each questionnaire had scoring of 0 representing not performing the step, 1 representing following the step the scores were high after pharmacist intervention when compared to before pharmacist intervention Conclusion: The present results highlight the need for pharmacist interventions aimed at improving adherence to inhalers in coped and asthmatic patients.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"216 1","pages":"01-05"},"PeriodicalIF":0.0,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88700862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Doses of Radiation Due To Natural Radioactivity in Wheat As Animal Feed In the Surrounding Of the City Of Skopje (Macedonia)

IOSR Journal of Pharmacy Pub Date : 2017-07-01 DOI: 10.9790/3013-0706012023

A. Aleksandra, Dimitrieska Stojkovik Elizabeta, Crceva Nikolovska Radmila, Hajrulai Musliu-Zehra, D. Biljana, Uzunov Riste, Jankuloski Dean

引用次数: 4

Composition of the Daily Food Ration in Ivory Coast 科特迪瓦每日食物配给的组成

IOSR Journal of Pharmacy Pub Date : 2017-06-01 DOI: 10.9790/3013-0701011214

D. A. Sahoré, O. Y. Ako, Joachim Levry Abouattier

引用次数: 2

Nutritional and therapeutic importance of Daucus carota- A review 胡萝卜的营养和治疗价值综述

IOSR Journal of Pharmacy Pub Date : 2017-06-01 DOI: 10.9790/3013-0702017288

A. Al-Snafi

引用次数: 61

A need to be fulfilled:Drug Information services 需要满足的需求:药物信息服务

IOSR Journal of Pharmacy Pub Date : 2017-06-01 DOI: 10.9790/3013-0706011519

C. Ahirwar, A. Mishra, A. Pathak

{"title":"A need to be fulfilled:Drug Information services","authors":"C. Ahirwar, A. Mishra, A. Pathak","doi":"10.9790/3013-0706011519","DOIUrl":"https://doi.org/10.9790/3013-0706011519","url":null,"abstract":"There are a growing number of drugs and vast literature coming through every day. Clinicians are hard pressed to keep up with all the recent advents due to shortage of time, however, for safe and efficacious use of medicines, unbiased, up to date and objective information about the drugs is essential. Medicines are now considered as active substances. Information obtained from manufacturers is liable to be biased, and in the present day of therapeutic and information explosion, a quick referral to a pharmacopoeia or formularies is hardly sufficient for adequate information on the vast number of drugs and dosage forms available in the market in all the different brand names. The lack of adequate drug information due to limited availability of current literature, and poor documentation and dissemination of the little available information leads to an unbiased and current drug references which were not available in most clinical facilities and to officials and committees developing drug lists and making procurement decisions. The irrational use of drugsare still in evidence as use of expired drugs, irrational combination of drugs, and overuse of antibiotics, Vitamins, herbal remedies, brand prescribing, retail shop prescribing and unethical dispensing. Such irrational practices, combined with lack of patientinformation on proper handling and use of drugs can lead to wastage of medicine as well as other serious consequences like adverse drug reactions and drug interactions. . In view of the above mentioned facts, fully active, unbiased and objective drug information services are the need of the hour and it is the objective of this study to determine the various drug information services available in present day sceneario.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"13 1","pages":"15-19"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87797331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Prevalence of Risk Factors for Non-Communicable Diseases in Mazar-e-Sharif city using WHO STEP-Wise Approach 使用世卫组织分步方法研究马扎里沙里夫市非传染性疾病风险因素的流行情况

IOSR Journal of Pharmacy Pub Date : 2017-06-01 DOI: 10.9790/3013-0701015158

Khwaja Mir Islam SAEED, M. H. Rasooly

{"title":"Prevalence of Risk Factors for Non-Communicable Diseases in Mazar-e-Sharif city using WHO STEP-Wise Approach","authors":"Khwaja Mir Islam SAEED, M. H. Rasooly","doi":"10.9790/3013-0701015158","DOIUrl":"https://doi.org/10.9790/3013-0701015158","url":null,"abstract":"Background: Afghanistan is suffering from double burden of diseases including communicable and noncommunicable. The aim of this study was determine the risk factors for NCDs among adult’s population in Mazar-e-Sharif city, Afghanistan. Methods and Materials: A provincial cross-sectional study was conducted from April to May 2015 on the prevalence of NCD risk factors using the WHO STEPS adapted instrument. The study enrolled a random sample of 1249 adults of age group of 25-70 years. Data were collected using a structured questionnaire. Fasting venous blood sample was collected to assess the lipid profile and fasting blood sugar. Anthropometric measurements of the participants were also taken. Data was analyzed using SPSS version 20. Results: Out of all (1231) respondents 664 (53.9%) were females and 567 (46.1%) males with a mean age of 40.5±13.2 years. More than half (59.3%) were illiterates and (83.7%) were married and 72% had income of less than 10000 AFN. 9.9% were smokers and (8.3%) were mouth snuff users. Seventy nine percent of respondents ate fruits and 60% took vegetables 3 days or less per week. Almost 12% practiced vigorous physical activity and 21.8% of subjects reported doing moderate physical activity. Almost half (48.5) of subjects were overweight or obese. 30.9% had high blood pressure and 9.2% percent recorded diabetic. Level of high cholesterol was 33.2%, high triglycerides was 20.4%. Furthermore high level of low density lipoprotein (LDL) was 55% and high level of high density lipoprotein (HDL) was 36.9%. The mean level of triglyceride, total cholesterol, HDL and LDL were 161.7 mg/dL, 179.2mg/dL, 49.4 mg/dL and 113.4 mg/dL were respectively. Conclusions: The findings of study revealed a high burden of risk factors for NCDs in the study population, showing the country is experiencing both communicable and noncommunicable at the same time. It is recommended and emphasized on focusing of interventions to prevent and control the noncommunicable diseases.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"88 1","pages":"51-58"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79383551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The pharmacology and medical importance of Dolichos lablab (Lablab purpureus)- A review 紫唇草(lablab purpureus)的药理和医学意义综述

IOSR Journal of Pharmacy Pub Date : 2017-06-01 DOI: 10.9790/3013-0702012230

A. Al-Snafi

引用次数: 75

Development and validation of a simple, fast, isocratic stability indicating RP-HPLC-UV method for the determination of chlorhexidine and its impurity para-chloroaniline in bulk and finished product 建立一种简单、快速、等密度稳定指示RP-HPLC-UV测定原料药和成品中氯己定及其杂质对氯苯胺的方法并进行验证

IOSR Journal of Pharmacy Pub Date : 2017-06-01 DOI: 10.9790/3013-0706010108

TarigG. Mohammed, Mubashira Aziz

{"title":"Development and validation of a simple, fast, isocratic stability indicating RP-HPLC-UV method for the determination of chlorhexidine and its impurity para-chloroaniline in bulk and finished product","authors":"TarigG. Mohammed, Mubashira Aziz","doi":"10.9790/3013-0706010108","DOIUrl":"https://doi.org/10.9790/3013-0706010108","url":null,"abstract":"A simple, isocraticRP HPLC-UV method was developed for the simultaneous determination of chlorhexidine (CHD) and p-Chloroaniline (pCA) inchlorhexidine mouth rinses. An excellent separation obtainedbyC18 column (200mm × 4.6 mm, 3μm). Mobile phasewas acetate buffer:methanol in a 45:55 ratio,flowrate was 1.0 ml/min. Both ingredient and an impuritywere detected at 254 nm,injection volume was 20μl and the analysis temperature was room temperature.Resolution4.7,retention times was3.1min and 5.7 min for pCAand CHD respectively. The proposed method was testedforsystem suitability, linearity, range, precision, accuracy, specificity, robustness, detection and quantification limits. The linearity range was40-160μg/ml forCHD and0.3-1.2 μg/ml forpCA.The correlation coefficient of the regression line was 1.000 for both components. Method robustness was tested under nine different conditions using sampleswith a known content. For CHD, the mean of the nine assays was 99.95% andthe RSD was 0.16%. ForpCA, the mean of the nine assays was 99.98% and the RSD was 0.24%. The results show that this is a simple method that can be applied to the analysis of Chlorhexidineproductswith satisfactory degrees of accuracy and precision. Due to the selected optimized conditions, this method can be used with the minimum requirements of an isocratic HPLC system.","PeriodicalId":14540,"journal":{"name":"IOSR Journal of Pharmacy","volume":"9 3 1","pages":"01-08"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83536196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

The effect of thermal, chlorine and ozone treatments on survival of Escherichia coli and Salmonella spp. in açai berries 热、氯和臭氧处理对猕猴桃中大肠杆菌和沙门氏菌存活的影响

IOSR Journal of Pharmacy Pub Date : 2017-06-01 DOI: 10.9790/3013-0701010411

V. Bezerra, E. Walter, O. Freitas-Silva, I. Gomes, L. F. Damasceno, I. Alcantara, L. Cabral

引用次数: 3