外科和儿科抗生素使用模式,Bhagwan Mahaveer Jain医院,班加罗尔,印度

M. Soleimani
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引用次数: 0

摘要

目的:了解外科和儿科的抗生素使用情况,并探讨抗生素使用不依从的原因。方法:对内科、外科和儿科收治的180例患者进行前瞻性临床记录回顾。评估抗生素处方是否符合医院抗生素政策,如违反,将记录原因。医院感染的发生率和原因将被记录下来。除了这些抗生素类别外,还将计算医疗账单中的抗生素治疗费用和抗生素的费用。结果:在我们的研究人群中,180例患者中男性110例,女性70例;在儿科人群中,男性占16%,女性占13.5%。在手术部门最多也就是12.5%的男性和9.5%的女性在年龄组31-40年。81-90岁年龄组男性占2%,女性占2.5%。医生开了各种抗生素,如青霉素、大环内酯类药物、头孢菌素和氟喹诺酮类药物。which13%男性,7%的女性都规定与青霉素的单一疗法中最高。在联合治疗中,14%的男性和7%的女性使用青霉素,比例最高。有多种针对该病的联合用药,其中氨苄西林+庆大霉素+甲硝唑(5%)和氨苄西林+庆大霉素+头孢噻肟+阿米卡星(5%)。结论:医院在抗菌药物处方前必须强制进行培养敏感性试验,导致抗菌药物使用不合理。应开成本效益较低的抗生素治疗。在很大程度上,患者使用4-5种抗生素,应适当使用广谱抗生素和固定剂量抗生素,以避免多药。药物与抗生素的相互作用也应尽量减少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antibiotic Utilization Pattern in Surgery and Pediatric, Bhagwan Mahaveer Jain Hospital, Bangalore, India
Objective: To assess antibiotic utilization pattern in surgery and pediatric and to explore reasons for the nonadherence. Methods: A prospective clinical record review was done on 180 patients admitted in the Medicine, Surgery, and Paediatrics. The antibiotic prescription will be assessed whether it is according to hospital antibiotic policy and in case of violation the reason for it will be noted down. The incidence and cause for the nosocomial infection will be noted down. Apart from these antibiotic categories, cost of antibiotic therapy from medical bills and the cost for the antibiotics will be calculated. Results: In our study population out of 180 patients 110 were male and 70 were female and in paediatric population16% were male and 1 3.5%. In surgery department highest number i.e. 12.5% male and 9.5% females are in the age group 31-40 years. 2% males and 2.5% females were in the age Group of 81-90. Various classes of antibiotics like penicillin’s, macrolides, cephalosporin’s and fluoroquinolones were prescribed. of which13% males, 7% females were prescribed with penicillin’s which were highest among monotherapy. Among combination therapy 14% of males were prescribed and 7 % females with penicillin which were highest. There were various combination drugs prescribed which are specific to the disease out of which ampicillin+gentamicin+metronidazole (5%) and ampicillin+gentamicin+cefotaxime+amikacin (5%). Conclusion: In appropriate use of antibiotics is detected due to lack of culture sensitivity test which has to make mandatory in the hospital before antibiotic prescription. Less cost effective antibiotic treatment should be prescribed. Polypharmacy was seen in a large extent were patients were put on 4-5 antibiotics which has to be avoided by using broad spectrum antibiotics and fixed dose antibiotics suitably. The drug interactions with antibiotics should be also minimized.
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