JAMA ophthalmology最新文献

{"title":"Can Medicare Data Describe COVID-19 Practice Pattern Changes?","authors":"Sean T Berkowitz, Avni P Finn","doi":"10.1001/jamaophthalmol.2024.6183","DOIUrl":"10.1001/jamaophthalmol.2024.6183","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"213-214"},"PeriodicalIF":7.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperacute Outer Retinal Dysfunction-A Retina on Fire.","authors":"Timothy M Boyce, Ian C Han","doi":"10.1001/jamaophthalmol.2024.6488","DOIUrl":"10.1001/jamaophthalmol.2024.6488","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"230-231"},"PeriodicalIF":7.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Generative Artificial Intelligence Guidelines of Ophthalmology Journals.","authors":"David E Rabinovitch, Jim S Xie, Adrien Lusterio, Andrew Mihalache, Marko M Popovic, Prashant D Tailor, Brendan Tao, Edward Margolin","doi":"10.1001/jamaophthalmol.2024.6229","DOIUrl":"10.1001/jamaophthalmol.2024.6229","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"256-260"},"PeriodicalIF":7.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11826427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importance of Thickness When Evaluating Choroidal Tumors.","authors":"Carol L Shields","doi":"10.1001/jamaophthalmol.2024.6182","DOIUrl":"10.1001/jamaophthalmol.2024.6182","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"240-241"},"PeriodicalIF":7.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperacute Outer Retinal Dysfunction.","authors":"Yizhe Cheng, Xinyu Liu, Jinglin Lu, Jianing Ren, Ping Fei, Meini Chen, Changting Tang, Jianping Zhang, Minglian Zhang, Miner Yuan, Limei Sun, Linyan Zhang, Aohan Hou, Yili Jin, Yanting Lai, Qiong Wang, Wenjia Yan, Shuya Ke, Xiaoxin Li, Xiaoyan Ding","doi":"10.1001/jamaophthalmol.2024.6372","DOIUrl":"10.1001/jamaophthalmol.2024.6372","url":null,"abstract":"<p><strong>Importance: </strong>Pattern recognition of pediatric retinal diseases can streamline the workup and guide the prognosis.</p><p><strong>Objective: </strong>To characterize the clinical features, retinal imaging findings, and 1-year prognosis of pediatric patients who experienced sudden, severe bilateral vision loss with diffuse ellipsoid zone (EZ) and external limiting membrane (ELM) disruptions after fever.</p><p><strong>Design, setting, and participants: </strong>This multicenter case series included 8 pediatric patients (16 eyes) who presented with an unusual set of clinical symptoms, including sudden, severe bilateral vision loss; nyctalopia; and diffuse EZ and ELM disruptions, subsequent to a febrile illness. The patients visited or were referred to a pediatric retina service between November 2022 and May 2023.</p><p><strong>Main outcome measures: </strong>Changes in visual acuity, visual field, electroretinography (ERG) results, and presence of characteristic retinal imaging signs during follow-up.</p><p><strong>Results: </strong>A total of 16 eyes from 8 children (6 boys and 2 girls) were included in this study; the patients' mean (SD) age was 5.1 (1.2) years (range, 3-7 years; median, 5.0 years). Their sudden bilateral vision loss occurred a mean of 16.1 days after fever onset. Initial symptoms included sudden vision loss, visual field constriction, nyctalopia, and dyschromatopsia. Baseline visual acuity was predominantly below counting fingers. A sudden, diffuse loss of the EZ and ELM was observed in all eyes with gradual recovery beginning around the fourth week. After 1 year, visual acuity showed substantial improvement in most cases, with 7 of 8 patients (88%) achieving 20/40 or better, including 4 patients (50%) achieving 20/25 or better. The macular EZ and ELM appeared intact in 12 eyes (75%) and 14 eyes (88%), respectively, while the extrafoveal regions remained absent of EZ and ELM. ERG revealed extinguished cone and rod responses in 8 patients (100%), and multifocal ERG remained extinguished despite the recovery of visual acuity in all 8 patients (100%).</p><p><strong>Conclusions and relevance: </strong>This case series identifies a potentially underrecognized disease in pediatric patients after fever characterized by sudden vision loss, diffuse EZ and ELM disruption, and distinct retinal imaging features. The term hyperacute outer retinal dysfunction is recommended as descriptive while further investigations are recommended to better understand its pathophysiology and optimal management strategies.</p>","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"222-229"},"PeriodicalIF":7.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11826433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding Vision Services at Federally Qualified Health Centers.","authors":"Sally S Ong","doi":"10.1001/jamaophthalmol.2025.0003","DOIUrl":"10.1001/jamaophthalmol.2025.0003","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":"251-252"},"PeriodicalIF":7.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exudative Retinal Detachment in Pediatric Coats Disease.","authors":"Francisco J López-Font, Jason C Fan, Audina M Berrocal","doi":"10.1001/jamaophthalmol.2024.6231","DOIUrl":"https://doi.org/10.1001/jamaophthalmol.2024.6231","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":"143 3","pages":"e246231"},"PeriodicalIF":7.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selenium vs Control for Graves Ophthalmopathy in a Selenium-Sufficient Area: A Randomized Clinical Trial.","authors":"Hwa Young Ahn, Min Joung Lee, Kyong Yeun Jung, Hyo-Jeong Kim, Eun Hye Jung, Chae Won Chung, Kyungsik Kim, Jinsun Jang, Young Joo Park, Jeong Kyu Lee, Sun Wook Cho","doi":"10.1001/jamaophthalmol.2024.6337","DOIUrl":"10.1001/jamaophthalmol.2024.6337","url":null,"abstract":"<p><strong>Importance: </strong>Graves ophthalmopathy significantly diminishes patients' quality of life due to its immune-mediated inflammatory effects on the orbital tissues. Selenium, with its antioxidative properties, has shown potential for improving Graves ophthalmopathy progression and quality of life (QOL); however, its effectiveness in selenium-sufficient regions is not well established.</p><p><strong>Objective: </strong>To determine whether selenium supplementation improves QOL in patients with mild to moderate Graves ophthalmopathy in selenium-sufficient regions.</p><p><strong>Design, setting, and participants: </strong>The Efficacy of Selenium Supplementation for Mild-to-Moderate Graves' Ophthalmopathy in a Selenium-Sufficient Area (SeGOSS) trial was a randomized, open-label multicenter study. Eighty-four patients with mild to moderate Graves' ophthalmopathy were enrolled; 70 completed the study. Participants were selected based on Graves ophthalmopathy diagnosis and sufficient selenium levels. Data were analyzed from October 2023 to March 2024.</p><p><strong>Interventions: </strong>Participants received selenium supplementation combined with vitamin B complex for 6 months.</p><p><strong>Main outcomes and measures: </strong>The primary outcome was improvements in Graves ophthalmopathy QOL (GO-QOL) scores at 6 months. Secondary outcomes included changes in GO-QOL scores at 3 months, the proportion of patients showing improvement based on GO-QOL scores, clinical activity score, and ophthalmic examinations at 3 months and 6 months, and changes in thyroid autoantibodies at 3 months and 6 months.</p><p><strong>Results: </strong>There was no improvement in changes in the total GO-QOL scores between the selenium group (31 female patients [83.8%] and 7 male patients [16.2%]; mean [SD] age, 40.8 [11.7] years) and control group (24 female patients [72.7%] and 9 male patients [27.3%]; mean [SD] age, 42.9 [14.2] years) for the primary outcome at 6 months (mean [SD], 12.2 [22.5] vs mean [SD], 11.2 [20.2]; difference, 0.9; 95% CI, -9.3 to 11.3; P = .85). However, at 3 months, a higher proportion of patients in the selenium group showed improved GO-QOL scores compared with the control group (78.4 vs 48.5%; difference, 0.30; 95% CI, 0.08-0.51; P = .01). The selenium group also had higher rates of improvement in proptosis reduction (49.5 vs 15.1%; difference, 0.31; 95% CI, 0.11-0.51; P = .01) at 3 months, though these effects were not sustained at 6 months.</p><p><strong>Conclusions and relevance: </strong>These results suggest that selenium supplementation did not improve QOL or clinical parameters in patients with mild to moderate GO in selenium-sufficient regions at 6 months. Some potential QOL benefits noted at 3 months supports consideration of further investigation of selenium for patients seeking treatment for Graves ophthalmopathy .</p><p><strong>Trial registration: </strong>Clinical Research Information Service Identifier KCT0004040.</p>","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Private Equity Acquisitions and Industry Payments in Ophthalmology.","authors":"Geronimo Bejarano, Hamid Torabzadeh, Durga Borkar, Christopher Whaley, Yashaswini Singh","doi":"10.1001/jamaophthalmol.2025.0002","DOIUrl":"10.1001/jamaophthalmol.2025.0002","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Slowing Geographic Atrophy-Hopeful Progress or Uncertain Benefit.","authors":"Huixun Jia, Xiaodong Sun","doi":"10.1001/jamaophthalmol.2024.6490","DOIUrl":"https://doi.org/10.1001/jamaophthalmol.2024.6490","url":null,"abstract":"","PeriodicalId":14518,"journal":{"name":"JAMA ophthalmology","volume":" ","pages":""},"PeriodicalIF":7.8,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}