International Journal of Technology Assessment in Health Care最新文献_第3页

A blueprint for health technology assessment capacity building: lessons learned from Malta. 卫生技术评估能力建设蓝图：马耳他的经验教训。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-02-29 DOI: 10.1017/S0266462324000072

Katharina Abraham, Ingelin Kvamme, Sylvana Magrin Sammut, Simone de Vries, Tanya Formosa, Rudy Dupree, Isaac Corro Ramos, Wim Goettsch, Margreet Franken

{"title":"A blueprint for health technology assessment capacity building: lessons learned from Malta.","authors":"Katharina Abraham, Ingelin Kvamme, Sylvana Magrin Sammut, Simone de Vries, Tanya Formosa, Rudy Dupree, Isaac Corro Ramos, Wim Goettsch, Margreet Franken","doi":"10.1017/S0266462324000072","DOIUrl":"10.1017/S0266462324000072","url":null,"abstract":"Objectives: The development and strengthening of health technology assessment (HTA) capacity on the individual and organizational level and the wider environment is relevant for cooperation on HTAs. Based on the Maltese case, we provide a blueprint for building HTA capacity.Methods: A set of activities were developed based on Pichler et al.'s framework and the starting HTA capacity in Malta. Individual level activities focused on strengthening epidemiological and health economic skills through online and in-person training. On the organizational level, a new HTA framework was developed which was subsequently utilized in a shadow assessment. Awareness campaign activities raised awareness and support in the wider environment where HTAs are conducted and utilized.Results: The time needed to build HTA capacity exceeded the planned two years accommodating the learning progress of the assessors. In addition to the planned trainings, webinars supplemented the online courses, allowing for more knowledge exchange. The advanced online course was extended over time to facilitate learning next to the assessors' daily tasks. Training sessions were added to implement the new economic evaluation framework, which was utilized in a second shadow assessment. Awareness by decision-makers was achieved with reports, posters, and an article on the current and developing HTA capacity.Conclusions: It takes time and much (hands-on) training to build skills for conducting complex assessment such as HTAs. Facilitating exchange with knowledgeable parties is crucial for succeeding as well as the buy-in of local managers motivating staff. Decision-makers need to be on-boarded for the continued success of HTA capacity building.","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139990021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparing future doctors for evidence-based practice: a study on health technology assessment awareness and its predictors in Malaysia. 培养未来医生的循证实践能力：关于马来西亚卫生技术评估（HTA）意识及其预测因素的研究。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-02-28 DOI: 10.1017/S0266462324000102

Nur Farhana Mohamad, Zawiah Mansor, Aidalina Mahmud, Izzuna Mudla Mohamed Ghazali, Roza Sarimin

{"title":"Preparing future doctors for evidence-based practice: a study on health technology assessment awareness and its predictors in Malaysia.","authors":"Nur Farhana Mohamad, Zawiah Mansor, Aidalina Mahmud, Izzuna Mudla Mohamed Ghazali, Roza Sarimin","doi":"10.1017/S0266462324000102","DOIUrl":"10.1017/S0266462324000102","url":null,"abstract":"Objectives: To determine the level of awareness of health technology assessment (HTA) and its predictors among clinical year medical students in public universities in Klang Valley, Malaysia.Methods: A cross-sectional study using the stratified random sampling method was conducted among clinical year medical students in four public universities in Klang Valley, Malaysia. Data on the level of awareness of HTA and its associated factors were collected using a self-administered online questionnaire. Descriptive, bivariate, and multivariate analyses were performed using IBM SPSS version 27 to determine the level of awareness of HTA and its predictors.Results: Majority (69 percent) of participants had a low level of awareness of HTA. The predictors of high-level awareness of HTA were attitude toward HTA (adjusted odds ratio (AOR) = 7.417, 95 percent confidence interval (CI): 3.491, 15.758), peer interaction on HTA (AOR = 0.320, 95 percent CI: 0.115, 0.888), and previous training on HTA (AOR = 4.849, 95 percent CI: 1.096, 21.444).Conclusions: Most future doctors in public universities exhibit a low awareness of HTA. This study highlights the interplay between attitudes toward HTA, peer interaction, and previous training as influential predictors of HTA awareness. An integrated and comprehensive educational approach is recommended to cultivate a positive attitude and harness the positive aspects of peer interaction while mitigating the potential negative impact of misconceptions. Emphasizing early exposure to HTA concepts through structured programs is crucial for empowering the upcoming generation of healthcare professionals, enabling them to navigate HTA complexities and contribute to evidence-based healthcare practices in Malaysia and beyond.","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139982879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conducting a health technology assessment in the West Bank, occupied Palestinian territory: lessons from a feasibility project. 在巴勒斯坦被占领土西岸开展卫生技术评估：可行性项目的经验教训。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-02-15 DOI: 10.1017/S0266462324000084

Mervett Isbeih, Lieke-Fleur Heupink, Sharif Qaddomi, Rand Salman, Lumbwe Chola

{"title":"Conducting a health technology assessment in the West Bank, occupied Palestinian territory: lessons from a feasibility project.","authors":"Mervett Isbeih, Lieke-Fleur Heupink, Sharif Qaddomi, Rand Salman, Lumbwe Chola","doi":"10.1017/S0266462324000084","DOIUrl":"10.1017/S0266462324000084","url":null,"abstract":"Objectives: To achieve universal health coverage (UHC), countries must make difficult choices to optimize the use of scarce resources. There is a growing interest in using evidence-based priority setting processes, such as Health Technology Assessment (HTA), to inform these decisions. In 2020, the Palestinian Institute of Public Health (PNIPH) and the Norwegian Institute of Public Health (NIPH) initiated a pilot to test the feasibility of coproducing an HTA on breast cancer screening in the West Bank, occupied Palestinian Territory. Additionally, a secondary aim was to test whether using an adaptive HTA (aHTA) approach that searched and transferred published evidence syntheses could increase the speed of HTA production.Methods: The applied stepwise approach to the HTA is described in detail and can be summarized as defining a core team, topic selection, and prioritization; undertaking the HTA including adaptation using tools from the European Network for HTA (EUnetHTA) and stakeholder engagement; and concluding with dissemination.Results: The aHTA approach was faster but not as quick as anticipated, which is attributed to (i) the lack of availability of local evidence for contextualizing findings and (ii) the necessity to build trust between the team and stakeholders. Some delays followed from the COVID-19 pandemic, which showed the importance of good risk anticipation and mitigation. Lastly, other important lessons included the ability of virtual collaborations, the value of capacity strengthening initiatives within low- and middle-income countries (LMICs), and the need for early stakeholder engagement. Overall, the pilot was successfully completed.Conclusion: This was the first HTA of its kind produced in Palestine, and despite the challenges, it shows that HTA analysis is feasible in this setting.","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139735105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating clinical decision support software (CDSS): challenges for robust evidence generation. 评估临床决策支持软件（CDS）--有力证据生成的挑战。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-02-08 DOI: 10.1017/S0266462324000059

Mah Laka, Drew Carter, Tracy Merlin

{"title":"Evaluating clinical decision support software (CDSS): challenges for robust evidence generation.","authors":"Mah Laka, Drew Carter, Tracy Merlin","doi":"10.1017/S0266462324000059","DOIUrl":"10.1017/S0266462324000059","url":null,"abstract":"Objectives: Computerized clinical decision support software (CDSS) are digital health technologies that have been traditionally categorized as medical devices. However, the evaluation frameworks for traditional medical devices are not well adapted to assess the value and safety of CDSS. In this study, we identified a range of challenges associated with CDSS evaluation as a medical device and investigated whether and how CDSS are evaluated in Australia.Methods: Using a qualitative approach, we interviewed 11 professionals involved in the implementation and evaluation of digital health technologies at national and regional levels. Data were thematically analyzed using both data-driven (inductive) and theory-based (deductive) approaches.Results: Our results suggest that current CDSS evaluations have an overly narrow perspective on the risks and benefits of CDSS due to an inability to capture the impact of the technology on the sociotechnical environment. By adopting a static view of the CDSS, these evaluation frameworks are unable to discern how rapidly evolving technologies and a dynamic clinical environment can impact CDSS performance. After software upgrades, CDSS can transition from providing information to specifying diagnoses and treatments. Therefore, it is not clear how CDSS can be monitored continuously when changes in the software can directly affect patient safety.Conclusion: Our findings emphasize the importance of taking a living health technology assessment approach to the evaluation of digital health technologies that evolve rapidly. There is a role for observational (real-world) evidence to understand the impact of changes to the technology and the sociotechnical environment on CDSS performance.","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139702465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Introduction of hospital-based health technology assessment in China: experiences from seven pilot hospitals. 在中国引入基于医院的卫生技术评估：七家试点医院的经验。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-01-29 DOI: 10.1017/S0266462323002738

Lanting Lyu, Wenkai Shi, Kristian Kidholm, Fei Bai, Xia Lin, Jinlan Fu, Tianqing Li, Guoxun Li, Li Luo, Ting Wang, Hai Yang

{"title":"Introduction of hospital-based health technology assessment in China: experiences from seven pilot hospitals.","authors":"Lanting Lyu, Wenkai Shi, Kristian Kidholm, Fei Bai, Xia Lin, Jinlan Fu, Tianqing Li, Guoxun Li, Li Luo, Ting Wang, Hai Yang","doi":"10.1017/S0266462323002738","DOIUrl":"10.1017/S0266462323002738","url":null,"abstract":"Objectives: This study aimed to introduce a pilot program for hospital-based health technology assessment (HB-HTA) in China and present the participants' experiences based on seven case studies from seven tertiary hospitals.Methods: One-year pilot projects were initiated at the beginning of 2018. Seven pilot hospitals were closely followed from the beginning until the completion of their pilot HTA project. Regular interviews were conducted with the hospital managers leading the HB-HTA projects and key members of the special HTA teams. Observations were made based on field trips and written HTA reports.Results: Three pilot projects evaluated the use of medical consumables, three evaluated the use of surgical or medical interventions, and one evaluated an innovative management model for ventilators. Real-world data were collected from all the pilot projects to assist with the assessments. Most HB-HTA pilot projects achieved remarkable results such as improvements in economic efficiency; however, there were also obvious deficiencies such as the lack of a necessary cost-effectiveness analysis.Conclusions: The results varied among the seven HB-HTA pilot projects. The HB-HTA pilot program was implemented to promote the use of HB-HTA in hospital decision making in China. At the same time, HB-HTA in China faces challenges. We have made some policy recommendations based on the findings of the pilot projects.","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139570327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early technology review: towards an expedited pathway. 早期技术审查：走向快速通道。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-01-29 DOI: 10.1017/S0266462324000047

Leslie Levin, Murray Sheldon, Robert S McDonough, Naomi Aronson, Maroeska Rovers, C Michael Gibson, Sean Robert Tunis, Richard E Kuntz

{"title":"Early technology review: towards an expedited pathway.","authors":"Leslie Levin, Murray Sheldon, Robert S McDonough, Naomi Aronson, Maroeska Rovers, C Michael Gibson, Sean Robert Tunis, Richard E Kuntz","doi":"10.1017/S0266462324000047","DOIUrl":"10.1017/S0266462324000047","url":null,"abstract":"Objectives: Evidence development for medical devices is often focused on satisfying regulatory requirements with the result that health professional and payer expectations may not be met, despite considerable investment in clinical trials. Early engagement with payers and health professionals could allow companies to understand these expectations and reflect them in clinical study design, increasing chances of positive coverage determination and adoption into clinical practice.Methods: An example of early engagement through the EXCITE International model using an early technology review (ETR) is described which includes engagement with payers and health professionals to better inform companies to develop data that meet their expectations. ETR is based on an early evidence review, a framework of expectations that guides the process and identified gaps in evidence. The first fourteen ETRs were reviewed for examples of advice to companies that provided additional information from payers and health professionals that was thought likely to impact on downstream outcomes or strategic direction. Given that limitations were imposed by confidentiality, examples were genericized.Results: Advice through early engagement can inform evidence development that coincides with expectations of payers and health professionals through a structured, objective, evidence-based approach. This could reduce the risk of business-related adverse outcomes such as failure to secure a positive coverage determination and/or acceptance by expert health professionals.Conclusions: Early engagement with key stakeholders exemplified by the ETR approach offers an alternative to the current approach of focusing on regulatory expectations. This could reduce the time to reimbursement and clinical adoption and benefit patient outcomes and/or health system efficiencies.","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139570321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acceptability of self-administered antigen test for COVID-19 in the Philippines. 菲律宾人对 COVID-19 抗原自测法的接受程度。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-01-17 DOI: 10.1017/S0266462324000035

Jayne Eunice U Yang, Faisal H Jackarain, Tisha Isabelle M de Vergara, Joshua F Santillan, Patrick Wincy C Reyes, Ma Cecilia Victoria B Arellano, Jainor Timothy U Garcia, Sheena Jasley G Samonte, Anne Julienne G Marfori, Anna Melissa S Guerrero

{"title":"Acceptability of self-administered antigen test for COVID-19 in the Philippines.","authors":"Jayne Eunice U Yang, Faisal H Jackarain, Tisha Isabelle M de Vergara, Joshua F Santillan, Patrick Wincy C Reyes, Ma Cecilia Victoria B Arellano, Jainor Timothy U Garcia, Sheena Jasley G Samonte, Anne Julienne G Marfori, Anna Melissa S Guerrero","doi":"10.1017/S0266462324000035","DOIUrl":"10.1017/S0266462324000035","url":null,"abstract":"Objectives: In response to the Omicron surge in early 2022, the HTA Philippines evaluated the acceptability of Filipinos in using self-administered antigen tests (SAAgTs) as part of COVID-19 HTAs in the Philippines.Methods: Scoping review from literature databases was initially conducted to identify preset codes in the use of SAAgT. Preset codes were used to establish the questions for focus group discussions (FGDs). Semi-structured questionnaires were created through Delphi technique. FGDs with four stakeholder groups (i.e., nine healthcare workers [HCWs], seven representatives of at-risk groups, six economic frontliners, and seven representatives of micro-small-medium-sized enterprises) were conducted.Results: Discomfort in being a target of stigma and being prescribed an \"illness identity\" when suspected or confirmed COVID-19-positive, along with lack of confidence to perform self-test, caused hesitancy in self-testing among participants. The need for subsidies for test kits from the government or employers was emphasized to increase its accessibility. Having a designated access point and reporting system for SAAgT was highlighted to avoid nepotism (padrino system attributed to debt of gratitude), inequitable distribution, and lapses in reporting. A participatory approach to education was perceived as crucial to reduce any misconceptions associated with the use of SAAgT.Conclusions: All FGD groups expressed favorable reviews on the implementation of SAAgT because it can potentially reduce the burden of health facility-administered tests. These findings were considered by the HTA Council in the recommendation of SAAgT as part of the overarching national strategies for the diagnosis and screening of COVID-19.","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to heterogeneity of tests and platforms in economic evaluations: synthetic model adoption; derivatives of transferable practice. 对经济评估中测试和平台异质性的回应：合成模型的采用；可转移实践的衍生物。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-01-15 DOI: 10.1017/S0266462323002787

Benjamin Jones

引用次数: 0

Quantifying stakeholders' preference for implantable medical devices in China: a discrete choice experiment. 量化利益相关者对中国植入式医疗器械的偏好：离散选择实验》。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-01-15 DOI: 10.1017/S0266462323002799

Bin Wan, Jiaojie Shen, Jiali Chen, Linjia Weng, Peng Zhao, Yunfei Deng, Lingli Zhang, Feiyi Zhang, Yingpeng Wang, Xin Li, Feng Chang, Haixia Ding, Yun Lu

{"title":"Quantifying stakeholders' preference for implantable medical devices in China: a discrete choice experiment.","authors":"Bin Wan, Jiaojie Shen, Jiali Chen, Linjia Weng, Peng Zhao, Yunfei Deng, Lingli Zhang, Feiyi Zhang, Yingpeng Wang, Xin Li, Feng Chang, Haixia Ding, Yun Lu","doi":"10.1017/S0266462323002799","DOIUrl":"10.1017/S0266462323002799","url":null,"abstract":"Objectives: This study aims to gain insight into each attribute as presented in the value of implantable medical devices, quantify attributes' strength and their relative importance, and identify the determinants of stakeholders' preferences.Methods: A mixed-methods design was used to identify attributes and levels reflecting stakeholders' preference toward the value of implantable medical devices. This design combined literature reviewing, expert's consultation, one-on-one interactions with stakeholders, and a pilot testing. Based on the design, six attributes and their levels were settled. Among 144 hypothetical profiles, 30 optimal choice sets were developed, and healthcare professionals (decision-makers, health technology assessment experts, hospital administrators, medical doctors) and patients as stakeholders in China were surveyed. A total of 134 respondents participated in the survey. Results were analyzed by mixed logit model and conditional logit model.Results: The results of the mixed logit model showed that all the six attributes had a significant impact on respondents' choices on implantable medical devices. Respondents were willing to pay the highest for medical devices that provided improvements in clinical safety, followed by increased clinical effectiveness, technology for treating severe diseases, improved implement capacity, and innovative technology (without substitutes).Conclusions: The findings of DCE will improve the current evaluation on the value of implantable medical devices in China and provide decision-makers with the relative importance of the criteria in pricing and reimbursement decision-making of implantable medical devices.","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10859836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139466468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The National Health Service urgent cancer referral pathway for suspected urological cancers: early economic evaluation of a risk prediction test. 英国国家医疗服务系统（NHS）疑似泌尿系统癌症紧急转诊路径：风险预测测试的早期经济评估。

IF 3.2 4区医学

International Journal of Technology Assessment in Health Care Pub Date : 2024-01-12 DOI: 10.1017/S0266462324000023

Paola Cocco, Alison Florence Smith, Richard D Neal, Bethany Shinkins

{"title":"The National Health Service urgent cancer referral pathway for suspected urological cancers: early economic evaluation of a risk prediction test.","authors":"Paola Cocco, Alison Florence Smith, Richard D Neal, Bethany Shinkins","doi":"10.1017/S0266462324000023","DOIUrl":"10.1017/S0266462324000023","url":null,"abstract":"Objectives: In the UK, the number of patients urgently referred for suspected cancer is increasing, and providers are struggling to cope with demand. We explore the potential cost-effectiveness of a new risk prediction test - the PinPoint test - to triage and prioritize patients urgently referred with suspected urological cancers.Methods: Two simulation models were developed to reflect the diagnostic pathways for patients with (i) suspected prostate cancer, and (ii) bladder or kidney cancer, comparing the PinPoint test to current practice. An early economic analysis was conducted from a UK National Health Service (NHS) perspective. The primary outcomes were the percentage of individuals seen within 2 weeks and health care costs. An exploratory analysis was conducted to understand the potential impact of the Pinpoint test on quality-adjusted life years gained.Results: Across both models and applications, the PinPoint test led to more individuals with urological cancer being seen within 2 weeks. Using PinPoint only to prioritize patients led to increased costs overall, whereas using PinPoint to both triage and prioritize patients led to cost savings. The estimated impact on life years gained/lost was very small and highly uncertain.Conclusions: Using the PinPoint test to prioritize urgent referrals meant that more individuals with urological cancer were seen within 2 weeks, but at additional cost to the NHS. If used as a triage and prioritization tool, the PinPoint test shortens wait times for referred individuals and is cost saving. More data on the impact of short-term delays to diagnosis on health-related quality of life is needed.","PeriodicalId":14467,"journal":{"name":"International Journal of Technology Assessment in Health Care","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10859831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139424707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0