International Orthopaedics最新文献

{"title":"Orthopaedic heritage in seventeenth Century Dutch and Flemish genre painting.","authors":"Fernando Canillas, Pablo Menéndez, Marta Canillas","doi":"10.1007/s00264-025-06597-y","DOIUrl":"10.1007/s00264-025-06597-y","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study is to explore the representation of professionals engaged in medico-surgical practices within seventeenth-century Dutch and Flemish genre painting. The research focuses on how these works of art mirror the rich diversity of healthcare practitioners, the techniques employed, the spaces of care depicted, and the societal perception of medical knowledge.</p><p><strong>Materials and methods: </strong>An extensive review has been conducted of the foremost museums and painting databases devoted to seventeenth-century Dutch and Flemish art related to the treatment of illness. Over one hundred and fifty works, created by some sixty painters active during this period, have been subjected to a meticulous formal and iconographic analysis.</p><p><strong>Results: </strong>The study unveils the coexistence of a multifaceted array of medical figures - from physicians and barber-surgeons to empirics and charlatans - and illustrates how paintings of the time portrayed urban, rural, and mercantile settings of medical practice. These visual narratives document surgical techniques, orthopaedic interventions, and the complex social dynamics between patients and healthcare providers. Furthermore, the works frequently incorporate satirical and allegorical elements that critique the pretensions of the medical elite, highlight surgical ineptitude, or expose the cunning of itinerant healers.</p><p><strong>Conclusion: </strong>Seventeenth-century genre painting serves as a vivid visual testament to the popular perception of medicine and provides invaluable insight into the tensions between academic medicine and empirical practice. These works offer a critical and nuanced lens through which to apprehend the medical culture and epistemologies of the period.</p>","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"2297-2307"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144540210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Variation in hip replacement rates and surgical workforce across Nordic European countries.","authors":"Ioannis Christofides, Job N Doornberg, Cees C Verheyen","doi":"10.1007/s00264-025-06587-0","DOIUrl":"10.1007/s00264-025-06587-0","url":null,"abstract":"","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"2029-2034"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144527949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is surgical resection of the primary site associated with longer survival in patients with metastatic chondrosarcoma at initial diagnosis?","authors":"Tomoya Masunaga, Shinji Tsukamoto, Kanya Honoki, Hiromasa Fujii, Akira Kido, Manabu Akahane, Yasuhito Tanaka, Andreas Mavrogenis, Costantino Errani, Akira Kawai","doi":"10.1007/s00264-025-06600-6","DOIUrl":"10.1007/s00264-025-06600-6","url":null,"abstract":"<p><strong>Purpose: </strong>Patients with metastatic chondrosarcoma at presentation have a poor prognosis. Owing to the lack of sensitivity to chemotherapy and radiotherapy, surgical resection is the mainstay of treatment of localized chondrosarcoma. The aim of this study was to investigate whether surgical resection of the primary site was associated with improved survival in patients with metastatic chondrosarcoma at presentation.</p><p><strong>Methods: </strong>Sixty-two patients with distant metastases at initial diagnosis who were pathologically diagnosed with grade 2 or 3 conventional chondrosarcoma, dedifferentiated chondrosarcoma, or mesenchymal chondrosarcoma between 2001 and 2022 and registered in the Japanese National Bone and Soft Tissue Tumour Registry database were analysed retrospectively. Propensity score matching was performed to correct for differences in background characteristics, including the number of organs affected by metastases, performance of metastasectomy, and performance of chemotherapy, between patients who underwent surgical resection of the primary site (N = 31) and those who did not (N = 31).</p><p><strong>Results: </strong>The median disease-specific survival was six months for the whole cohort, 12 months for the patients who underwent surgical resection of the primary site, and two months for the patients who did not. Overall, 37 patients (59.7%) died of the disease. Univariate analysis showed a better disease-specific survival for patients who underwent surgical resection of the primary site compared with patients who did not (2-year disease-specific survival 51.0% [95% CI: 32.3-69.4] vs. 19.3% [95% CI: 6.9-43.7]; P = 0.005).</p><p><strong>Conclusion: </strong>Surgical resection of the primary site may increase the survival of patients with metastatic chondrosarcoma at presentation.</p>","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"2219-2226"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144560095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of supraspinatus retraction size on functional outcome after arthroscopic direct repair.","authors":"Alejandro Pagan-Conesa, Carlos Verdu-Aznar, Alejandro Lizaur-Utrilla, Flores Vizcaya-Moreno","doi":"10.1007/s00264-025-06606-0","DOIUrl":"10.1007/s00264-025-06606-0","url":null,"abstract":"<p><strong>Purpose: </strong>The objective was to assess whether the size of the supraspinatus tendon retraction following a degenerative full-thickness rotator cuff tear influenced the functional outcome after arthroscopic direct repair.</p><p><strong>Methods: </strong>A prospective comparative cohort study of 65 patients underwent arthroscopic rotator cuff repair with a follow-up of 24 months. The mean age was 60.0 years (SD, 9.2). According to the supraspinatus tendon retraction, patients were included into the shorter retraction group (≤ 20 mm; n = 32) and longer retraction group (> 20 mm; n = 33). Clinical outcomes were assessed with the Constant-Murley score and visual analogue scale for pain. Radiological evaluation included magnetic resonance imaging (MRI).</p><p><strong>Results: </strong>Postoperatively, both groups significantly improved functional and pain outcomes, with no significant differences at the final follow-up (p = 0.671). The mean time interval between the onset of patient-reported symptoms and surgery was not significantly correlated with the retraction size (r = 0.12, p = 0.066). The multivariate analysis did not show significant predictors of satisfactory functional outcome, especially the tendon retraction size (OR 1.0; 95% CI 0.9-1.1; p = 0.728).</p><p><strong>Conclusion: </strong>In degenerative tears, the size of the supraspinatus tendon retraction was not correlated with the duration of the symptoms. The tendon retraction of up to 4 cm did not influence the functional outcome at 24 postoperative months, regardless of the arthroscopic repair technique of one or two rows.</p>","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"2139-2144"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"International orthopaedics\", the SICOT flag-carrier, over one million downloaded papers in 2024, unprecedented volume and visibility, facts about the journal that prepares its fiftieth volume starting January 2026.","authors":"Marius M Scarlat, Philippe Hernigou, Maurice Hinsenkamp, Andreas Mavrogenis, Vikas Khanduja","doi":"10.1007/s00264-025-06628-8","DOIUrl":"10.1007/s00264-025-06628-8","url":null,"abstract":"","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"2013-2020"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurologic and psychiatric disorders as risk factors following hip arthroplasty: results from the German arthroplasty registry.","authors":"Nele Wagener, Alexander Grimberg, Yinan Wu, Sebastian Hardt, Carsten Perka","doi":"10.1007/s00264-025-06593-2","DOIUrl":"10.1007/s00264-025-06593-2","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated whether neurologic and psychiatric disorders (ICD-10 F00-F99, G00-G99) increase postoperative complications and mortality after hip arthroplasty and identified subgroups with distinct complication patterns, including dislocations, loosening, fractures, and elevated mortality.</p><p><strong>Methods: </strong>We analyzed 190,340 primary cementless hip arthroplasties from the German Arthroplasty Registry (2012-2024). Patients with relevant diagnoses were compared to matched controls (1:1 Mahalanobis distance) across subgroups F00-F99 and G00-G99, adjusting for age, sex, BMI, Elixhauser Index, and arthroplasty type. Primary endpoints were implant survival (time to revision) and all-cause mortality over up to eight years. Revision causes including periprosthetic fracture, infection, dislocation, loosening, and others were systematically recorded.</p><p><strong>Results: </strong>Most subgroups showed significantly higher revision rates (p < 0.0001 for F00-F09, F10-F19, F30-F39, G20-G26, G40-G47, G60-G64). Mortality was also significantly higher (p < 0.0001 for F00-F09, F10-F19, F30-F39). Schizophrenia (F20-F29) increased revision (p < 0.0001) and mortality (p < 0.0001). Organic mental disorders (F00-F09) showed markedly elevated revision and mortality rates, with more frequent dislocations and fractures (p < 0.0001). Extrapyramidal disorders (G20-G26) mainly increased dislocation risk (p = 0.00032), while degenerative diseases (G30-G32) raised mortality (p < 0.0001). Episodic/paroxysmal disorders (G40-G47) increased loosening (p = 0.0041) and revision (p < 0.0001). Polyneuropathies (G60-G64) were linked to joint instability and dislocations (p = 0.0008).</p><p><strong>Conclusion: </strong>Neurologic and psychiatric disorders significantly elevate revision and mortality risks following hip arthroplasty. Subgroup-specific vulnerabilities, dislocations/fractures (F00-F09), high complication and mortality (F10-F19), and joint instability (G60-G64), highlight the need for individualized perioperative strategies and close postoperative monitoring to improve outcomes.</p>","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"2035-2046"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foot compartment syndrome treatment: a systematic review.","authors":"Mariana Tapia-Nañez, Humberto de Leon-Gutierrez, Neri Alejandro Alvarez-Villalobos, Jorge Gutierrez-de-la-O, Jose Felix Vilchez-Cavazos, Rodrigo Teran-Garza, Abraham Guadalupe Espinosa-Uribe, Santos Guzman-Lopez, Alejandro Quiroga-Garza, Rodrigo Enrique Elizondo-Omaña","doi":"10.1007/s00264-025-06566-5","DOIUrl":"10.1007/s00264-025-06566-5","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the treatment approaches for foot compartment syndrome (FCS) and evaluate their outcomes.</p><p><strong>Methods: </strong>A systematic review was conducted in MEDLINE, EMBASE, Mayo journals via OVID Databases, Web of Science, and Scopus from each database's inception to December 2024. Two reviewers, independently working in duplicate, assessed each manuscript's title, abstract, and full text for eligibility. Study characteristics, quality of evidence, and outcomes were obtained and analyzed.</p><p><strong>Results: </strong>A total of 45 articles were included in the qualitative analysis, 38 case reports, and seven  cohort studies. Among the case reports, only two patients underwent conservative management, while all remaining cases, as well as all cohort studies, reported fasciotomy as the primary treatment. Trauma was the most frequently identified cause of FCS, and the diagnostic criterion commonly used was an intracompartmental pressure exceeding 30 mmHg. There was no consensus on the number or anatomical location of incisions. Due to the heterogeneity of the data, a meta-analysis could not be performed to assess the risk associated with different incision approaches.</p><p><strong>Conclusion: </strong>Fasciotomy remains the standard treatment for FCS. However, there is insufficient evidence to determine the optimal number and location of surgical incisions. While existing data suggest that using two or more incisions may be associated with fewer long-term sequelae, further research is needed to establish specificity of compartment decompression to enhance treatment recommendations.</p>","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"2239-2249"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vancomycin-soaking of the graft significantly reduces the incidence of septic arthritis following anterior cruciate ligament reconstruction: comparison of cohorts from the Single-Centre database.","authors":"Tomislav Kottek, Barbara Kunovac, Goran Vrgoč, Alan Ivković, Saša Janković","doi":"10.1007/s00264-025-06594-1","DOIUrl":"10.1007/s00264-025-06594-1","url":null,"abstract":"<p><strong>Purpose: </strong>Presoaking of hamstrings autograft in vancomycin solution has been associated with significant reduction of post-operative septic arthritis rate after anterior cruciate ligament (ACL) reconstruction. The purpose of this study was to evaluate this effect by comparison of cohorts from the single-centre database.</p><p><strong>Methods: </strong>In a period between January 2018 and November 2023, 1329 patients underwent ACL reconstruction surgery at our institution, with a newly introduced technique of soaking the hamstrings autografts in a 5-mg/ml vancomycin solution. Data was retrospectively analysed to identify post-operative knee septic arthritis rate amongst this group. Results were compared with the results from our previous study, which included 1891 patients from January 2007 to December 2017, when ACL reconstruction surgery was made at our institution without soaking the autografts in vancomycin solution.</p><p><strong>Results: </strong>Results showed that one (0,07%) out of 1329 patients who underwent ACL reconstruction with vancomycin-soaking of the graft developed knee joint infection after the surgery, while using the old method the infection rate was 1,4%. Statistical analysis showed that there is a significant difference in the infection rate between two groups (OR, 0,05 [95% CI, 0.0073-0.3982]; p < 0.01).</p><p><strong>Conclusion: </strong>Presoaking of the hamstrings graft for ACL reconstruction in 5 mg/ml vancomycin solution as an addition to standard pre-operative intravenous antibiotic prophylaxis is associated with significant reduction of post-operative infection rate.</p>","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"2097-2102"},"PeriodicalIF":2.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144527948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cadaveric analysis of articular involvement following placement of tibiotalocalcaneal retrograde nail.","authors":"Elive Likine, Jordan Pamplin, Hari Ankem, Thomas Poynter, Nicolas Laco, Rodolfo Zamora","doi":"10.1007/s00264-025-06562-9","DOIUrl":"10.1007/s00264-025-06562-9","url":null,"abstract":"<p><strong>Objective: </strong>Previous studies have analyzed Tibiotalocalcaneal (TTC) nail placement and proximity to neurovascular structures. However, there is a paucity of literature regarding the bony/articular involvement following nail placement. The objective of this study is to analyze calcaneus, talus, and tibia bone structures and articular involvement of the tibiotalar and subtalar joints following TTC nail placement.</p><p><strong>Materials/methods: </strong>Ten fresh-frozen cadaver legs were utilized without previous injuries or surgeries. Prior to nail placement, the tibiotalar and subtalar joints were arthroscopically evaluated for any pre-existing defects or bony abnormalities. The starting point for a TTC nail was established using fluoroscopic guidance with anteroposterior, lateral, and calcaneal views. Following nail placement, each specimen was dissected to analyze for any compromise of the plantar neurovascular bundles and surrounding bone structures. Measurements of nail involvement of the tibiotalar and subtalar joints were recorded.</p><p><strong>Results: </strong>An arthroscopic evaluation of the specimen before nail insertion confirmed no cartilage abnormalities in any specimen. After nail insertion, four of ten (40%) of the specimens had a partial breach of the medial wall of the calcaneus with no associated fracture. There was no damage to the neurovascular bundles. On average, the subtalar joint had 4.7% of the total cross-sectional area involved in the posterior subtalar facet. In the tibiotalar joint, there was no additional involvement of the articular surface on the talar dome or tibial plafond outside the nail diameter. There was no breach of the walls of the talar dome or tibial plafond.</p><p><strong>Conclusion: </strong>There was no significant damage to the surrounding neurovascular structures or soft tissues. The posterior subtalar facet had minimal involvement after a TTC nail placement. A more lateral and anterior entry point may avoid a medial wall breach and avoid the posterior subtalar facet.</p>","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"1981-1987"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Kocher-Langenbeck approach combined with TiRobot-assisted percutaneous anterior column screw fixation for transverse with or without posterior wall fractures of acetabulum: a retrospective study.","authors":"Xiaolong Yu, Yutao Zhu, Wuyuanhao Lin, Jiaxin Zhao, Bin Zhang, Tao Nie","doi":"10.1007/s00264-025-06571-8","DOIUrl":"10.1007/s00264-025-06571-8","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purposes: &lt;/strong&gt;To compare radiological and clinical outcomes of TiRobot-assisted versus traditional freehand percutaneous anterior column screw fixation for transverse with or without posterior wall fractures of acetabulum based on the Kocher‑Langenbeck (K‑L) approach.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Patients suffering transverse with or without posterior wall fractures of acetabulum that were fixed by TiRobot-assisted or traditional freehand percutaneous anterior column screw fixation via the K-L approach were divided into two groups:group A (TiRobot-assisted fixation) and group B (traditional freehand fixation). Surgical time, blood loss, postoperative complications, follow-up length, hospital stay and fracture healing time were recorded. Fracture reduction quality was estimated via criteria described by Matta.Fracture healing was evaluated on the pelvic radiographs at each follow-up. Functional outcomes were examined using the Postel Merle D'Aubigné score system at the final follow-up.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 29 patients who met the inclusion and exclusion criteria were evaluated for eligibility in this study, with 16 patients assigned to group A and 13 to group B.The mean intraoperative blood loss was 581.3 ± 242.8 ml in group A and 761.5 ± 193.8 ml in group B(P &lt; 0.05). The average intraoperative fluoroscopy in group A was 8.3 ± 1.5 times, while that in group B was 12.7 ± 2.0 times(P &lt; 0.001). The mean number of needle adjustments was 0.6 ± 0.6 in group A and 2.0 ± 0.7 in group B(P &lt; 0.001). No signifcant differences in surgical time of the anterior column screw fixation,hospital stay,reduction quality, fracture healing time, complications and functional outcomes were noted between the two groups. It is worth noting that, in TiRobotic-assistance early-stage group the mean surgical time of anterior fracture fixation was 29.3 ± 2.5 min, while it was 19.3 ± 2.2 and 26.7 ± 4.2 min in Tirobotic-assistance late-stage group and freehand group respectively, with a statistically significant inter-group difference (P &lt; 0.001).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The K‑L approach combined with TiRobot‑aided anterior column screw fixation is a safe and effective option for transverse with or without posterior wall fractures of acetabulum. Compared with traditional freehand percutaneous anterior column screw fixation, TiRobot‑aided screw fixation has obvious advantages on blood loss, invasiveness, screw placement accuracy, patient and physician radiation exposure. Tirobot‑aided screw fixation involves a learning curve. During the initial phase, the surgical time is prolonged due to unfamiliarity with the technology; however, as proficiency improves, the surgical time is significantly reduced compared to traditional freehand technique. The K‑L approach combined with traditional freehand percutaneous anterior column screw fixation can also be a reliable alternative for transverse with or without posterior wall fractures of","PeriodicalId":14450,"journal":{"name":"International Orthopaedics","volume":" ","pages":"1989-1999"},"PeriodicalIF":2.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144333061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}