Syed Zaeem Haider Zaidi, M V Mithila, Ramesh Nanjundaiah Mavathur, R Nagarathna, Arun Thulasi, Atmika Y Ramsahaye, Katla Naresh, Himanshu A Shukla
{"title":"Yoga Module Development and Validation for Sickle Cell Disease.","authors":"Syed Zaeem Haider Zaidi, M V Mithila, Ramesh Nanjundaiah Mavathur, R Nagarathna, Arun Thulasi, Atmika Y Ramsahaye, Katla Naresh, Himanshu A Shukla","doi":"10.4103/ijoy.ijoy_169_23","DOIUrl":"10.4103/ijoy.ijoy_169_23","url":null,"abstract":"<p><strong>Introduction: </strong>Sickle cell disease (SCD) is a genetic blood disorder that affects the shape and function of red blood cells (RBCs), which can lead to several health problems affecting the quality of life. SCD can be treated with certain expensive treatments such as RBC transfusion, hydroxyurea, stem cell transplantation, gene therapy, or bone marrow transplant. However, some of the most common symptoms such as pain, anxiety, and stress can also be alleviated with alternative therapies like yoga. In light of this, there is a need for the development of a specific yoga module (YM) for SCD that can complement the current therapies.</p><p><strong>Objective: </strong>To develop and validate a YM for SCD.</p><p><strong>Methodology: </strong>Concise literature reports on yoga practices used for varied symptoms/comorbidities associated with SCD were compiled and presented to focus groups. Based on the presented report and personal experience, the focus group created a preliminary version of the module. The preliminary module was further refined based on content validity ratio (CVR) following module validation by 33 yoga experts.</p><p><strong>Results: </strong>One hour ten minutes module developed by the focus group had in total 27 practices including, loosening exercises, <i>asanas</i>, <i>pranayama</i>, relaxation techniques, and meditation. After validation by the experts, 21 practices with a CVR ≥ 0.33 were retained. The predominant reason for excluding 12 practices was intensity, which may have some adverse effect on sickle cell comorbidities.</p><p><strong>Conclusion: </strong>The module developed is the first validated module for SCD.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10919411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Applying Yogic Knowledge to Medical Practice.","authors":"Thomas J Beckman","doi":"10.4103/ijoy.ijoy_89_23","DOIUrl":"10.4103/ijoy.ijoy_89_23","url":null,"abstract":"<p><p>The body and mind are instruments that, through the senses, provide a gateway to conscious experience. One could reduce the totality of human existence to the body and mind alone, yet superficial appearances can be misleading. According to the yogic system, humans are comprised progressively subtle sheaths or koshas, ranging from the physical to the mind, energy, intellect, and bliss body. Furthermore, harnessing the intellect brings a level of control over energy, thoughts, behaviors, and quality of life. This understanding reorients the traditional, allopathic approach, which tends to emphasize the physical body in terms of anatomy, physiology, and clinical pathology. Recognizing deeper layers of self reminds physicians to see patients more holistically, while empowering patients to have greater authority over their own health outcomes.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Barriers and Facilitators to Yoga for Obesity, Diabetes, and Hypertension: A Qualitative Systematic Review Protocol.","authors":"Kaushik Chattopadhyay, Isha Biswas, Haiquan Wang","doi":"10.4103/ijoy.ijoy_138_23","DOIUrl":"10.4103/ijoy.ijoy_138_23","url":null,"abstract":"<p><p>The global burden of obesity, diabetes, and hypertension is high and increasing. Several systematic reviews suggest yoga, an ancient mind-body discipline from the Indian subcontinent, is safe and can be beneficial for preventing and managing obesity, diabetes, and hypertension. Several qualitative studies have been conducted to explore barriers and facilitators to yoga practice among people at high risk of or with obesity, diabetes, or hypertension and providers who delivered yoga to these people. However, no systematic review on this topic has been conducted to date, and this systematic review will aim to synthesize such barriers and facilitators to yoga practice. We will follow the JBI guideline on systematic reviews of qualitative evidence. For published studies, we will search the following electronic databases from inception dates: MEDLINE, EMBASE, CINAHL Plus, APA PsycInfo, AMED, and Web of Science. For gray literature, we will search EthOS and ProQuest Dissertations and Theses. Screening of studies, methodological quality assessment, and data extraction will be performed independently by two reviewers. Any disagreements between reviewers will be resolved through discussion or by involving a third reviewer. Initially, a narrative synthesis will be conducted. Study findings from the included studies will be pooled using the meta-aggregation approach, where possible. <b>Systematic Review Registration Number:</b> PROSPERO (CRD42020220640).</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breath Phase Durations, Affect, and Attention: A Pilot Randomized Crossover Trial.","authors":"Shirley Telles, Sachin Kumar Sharma, Ankur Kumar, Kumar Gandharva, Acharya Balkrishna","doi":"10.4103/ijoy.ijoy_53_23","DOIUrl":"10.4103/ijoy.ijoy_53_23","url":null,"abstract":"<p><strong>Objectives: </strong>Previously, yoga volitional breathing with low inspiration to expiration ratios (i/e) (as in <i>bhramari pranayama</i>) improved cognition and reduced state anxiety. This study compared the effects of low, high and equal i/e ratio breathing on affect and attention.</p><p><strong>Material and methods: </strong>Affect, vigor and attention were assessed in forty healthy participants (group mean age± SD; 22.58±3.83; M:F= 2.33:1) while breathing with three different i/e regulated by a visual metronome on separate days viz., (i) low i/e (28:72), (ii) equal i/e (50:50), (iii) high i/e (72:28) compared to control, without conscious breath modification. Assessments were: (i) brief mood introspection scale (BMIS), (ii) global vigor and affect scale (GVAS), (iii) Spielberger's state trait anxiety inventory-state (STAI-S) and a six letter cancellation test to assess sustained attention. Data were analyzed with repeated measures analysis of variance with Bonferroni adjusted <i>post-hoc</i> tests.</p><p><strong>Results: </strong>Pleasant feelings increased after low and equal i/e. Low i/e also increased positive feelings whereas equal i/e decreased scores in the cancellation test for sustained attention. All three breathing practices and the control session decreased state anxiety and increased vigor. High i/e breathing alone did not decrease negative feelings. For all the breath ratios the breath frequency cue was set at twelve breaths per minute.</p><p><strong>Conclusion: </strong>In summary, varying breath phase ratios influenced positive and pleasant feelings but did not influence state anxiety or vigor. Understanding the mechanisms underlying the findings would be improved with concurrent physiological assessments.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kamlesh Jha, Pankaj Kumar, Yogesh Kumar, C P Ganashree, Chandrabhushan Tripathi, B K Shrikant
{"title":"The Effectiveness of Rajyoga Meditation as an Adjuvant for Panic Anxiety Syndrome.","authors":"Kamlesh Jha, Pankaj Kumar, Yogesh Kumar, C P Ganashree, Chandrabhushan Tripathi, B K Shrikant","doi":"10.4103/ijoy.ijoy_149_23","DOIUrl":"10.4103/ijoy.ijoy_149_23","url":null,"abstract":"<p><strong>Objective: </strong>One of the most prevalent psychiatric conditions that affect a person's quality of life, ability to function and productivity, and consequently the loss of national income, are anxiety disorders. Rajyoga meditation (RM) is a form of meditation that is performed without rituals or mantras and can be practiced anywhere at any time. In this study, we attempted to evaluate the modulation of psycho-physiological parameters in panic disorder patients by a technique of short-term on RM.</p><p><strong>Methods: </strong>In this prospective randomized control study, 110 patients with panic disorder were randomized into two groups, Group A (standard treatment + RM) and Group B (Standard treatment). The participants of both group participants were subjected to sleep quality score, Physical Health Questionnaire-9 score, Panic Disorder Severity Scale (PDSS), and Hamilton Anxiety Rating Scale (HAM-A) questionnaires before starting the study (baseline) and at the end of the 8<sup>th</sup> week. Study groups were compared at baseline and at the end of 8 weeks.</p><p><strong>Results: </strong>We found that the PDSS/HAM-A was not statistically different among the study groups at baseline (<i>P</i> > 0.05); however, there was a statistically significant difference in mean z-scores of PDSS and post-HAM-A scores among the study groups at 8 weeks (<i>P</i> < 0.001). The composite score was created by adding the z-scores of pre- and post-PDSS and HAM-A. We found a statistically significant difference in postcomposite scores between the study groups (<i>P</i> < 0.001). Analysis of co-variance for PDSS and HAM-A among study groups showed statistical significance (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>When used in conjunction with pharmaceutical treatments for the treatment of panic disorder, RM is a successful therapy. The key factors are adherence and motivation while being supervised by a licensed therapist.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond the Mat: Exploring the Potential Clinical Benefits of Yoga on Epigenetics and Gene Expression: A Narrative Review of the Current Scientific Evidence.","authors":"Selvaraj Giridharan","doi":"10.4103/ijoy.ijoy_141_23","DOIUrl":"10.4103/ijoy.ijoy_141_23","url":null,"abstract":"<p><p>Yoga, an ancient practice rooted in Indian philosophy, has gained widespread popularity for its numerous physical and mental health benefits. In the recent years, there has been growing interest in understanding how yoga influences gene expression and epigenetic modifications. This narrative review investigates the molecular mechanisms, by which yoga influences gene expression, focusing on deoxyribonucleic acid (DNA) methylation, and histone modifications. Research literature was sourced from various databases to select randomized clinical trials and comparative cohort studies examining yoga's impact on gene expression and epigenetic changes. Our findings suggest that yoga could exert anti-inflammatory effects, as it downregulates pro-inflammatory cytokines, soluble interleukin IL-2 receptor gene expression, and transcription factors. Yoga also boosts the innate antiviral response and brain health by enhancing natural defense genes and microRNA-29c expression. Notably, it activates telomerase, linked with cellular longevity, and promotes nitric oxide synthetase and neuroprotective gene expression, implying benefits for ocular health. In addition, yoga fosters DNA repair and cellular integrity maintenance by increasing oxoguanine glycosylase one protein and p53 gene expression. However, the diversity of yoga interventions in these studies complicates direct comparisons and broader application. The current research primarily focuses on short-term outcomes, offering a limited understanding of yoga's long-term epigenetic impacts. Future research should address these gaps by studying the enduring effects of Yoga, personalizing interventions, and contrasting techniques.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heart-brain Rhythmic Synchronization during Meditation: A Nonlinear Signal Analysis.","authors":"Shrivastava Anurag, Bikesh Kumar Singh, Dwivedi Krishna, Krishna Prasanna, Singh Deepeshwar","doi":"10.4103/ijoy.ijoy_161_23","DOIUrl":"10.4103/ijoy.ijoy_161_23","url":null,"abstract":"<p><strong>Background: </strong>Heart-brain synchronization is the integration of mind, body, and spirit. It occurs when the electrical activity of the heart and brain is synchronized. In recent years, there has been mounting curiosity to investigate the effects of meditation on heart-brain synchronization with respect to mental and emotional health and well-being. The current investigation aims to explore the rhythmic synchronicity between the brain and the heart during heartfulness meditation (HM) practice.</p><p><strong>Materials and methods: </strong>The study was performed on 45 healthy volunteers who were categorized into three equal groups: long-term meditators (LTMs), short-term meditators (STMs), and nonmeditators (NMs). The electroencephalogram (EEG) signals were recorded to measure the prefrontal activity, and electrocardiogram (ECG) signals were recorded to measure the cardiac activity. The data were recorded in four states: baseline, meditation, transmission, and posttransmission. The detrended fluctuation analysis (DFA) method was used for the analysis of EEG and ECG signals.</p><p><strong>Results: </strong>The result indicates that DFA values of EEG and ECG declined during meditation and transmission states as compared to pre- and postmeditation states. Significant results were obtained for the LTM group in all the states. A positive correlation was also observed between DFA of the heart and brain for the LTM group and no significant correlations were observed for the STM and NM groups.</p><p><strong>Conclusion: </strong>The shreds of evidence suggest that heart-brain synchronization facilitates mental and emotional stability. HM practice has the potential to regulate the fluctuation of the mind. Regular meditation practice may result in physiological synchrony between cardiac and neural behavior, which can be considered a quality index for meditation practice.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19-induced Stress in Health-care Workers: Effect of 8-week Common Yoga Protocol on Autonomic Function and Inflammatory and Oxidative Stress Markers.","authors":"Vivek Kumar Sharma, Rajesh Kathrotia, Pradip B Barde, Gaurav Sharma, Vinay Chitturi, Naresh Parmar, Gauravi Dhruva, Ghanshyam Kavathia","doi":"10.4103/ijoy.ijoy_127_23","DOIUrl":"10.4103/ijoy.ijoy_127_23","url":null,"abstract":"<p><strong>Background: </strong>COVID-19 pandemic posed a huge stress on health-care givers affecting their physical and mental health. Wellness strategies like yoga can improve flexibility, resilience, and outlook.</p><p><strong>Aim: </strong>The present study explored the effect of 8-week standard common yoga protocol (CYP) intervention on autonomic functions, emotional stress, oxidative stress, and inflammation markers in the nurse group of health-care givers.</p><p><strong>Materials and methods: </strong>It is a randomized controlled trial where 50 nurses underwent CYP and 50 participated as controls. Anthropometric parameters, cardiovascular parameters, autonomic function including time and frequency domain parameters, biochemical parameters, and psychological stress using the questionnaire were assessed before and after 8-week CYP.</p><p><strong>Results: </strong>Total 88 nurses completed the study with 42 and 46 participants, respectively, in the CYP and control groups. CYP intervention resulted in a significant reduction in cardiovascular parameters systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse pressure, and rate pressure product (<i>P</i> < 0.001, <i>P</i> < 0.001, <i>P</i> < 0.001, <i>P</i> < 0.001, and <i>P</i> = 0.002, respectively), perceived stress score and Depression, Anxiety, and Stress Scale psychological variables of depression, anxiety, and stress, and serum lipid parameters compared to the control group. CYP significantly increased total power, low frequency, high frequency, root mean square of successive differences between adjacent NN intervals, change in successive normal sinus (NN) intervals exceeds 50 ms, and pNN50% (<i>P</i> < 0.001, <i>P</i> = 0.006, <i>P</i> = 0.006, <i>P</i> = 0.039, <i>P</i> < 0.001, and <i>P</i> = 0.013, respectively) suggesting improved resting autonomic modulation and parasympathodominance due to higher vagal efferent activity. There were significant reductions in serum cortisol, tumor necrosis factor-alpha, interleukin (IL)-1, and IL-6 in both the groups. Serum telomerase significantly reduced (<i>P</i> = 0.024) and total antioxidant capacity (<i>P</i> = 0.036) increased in the CYP group post intervention.</p><p><strong>Conclusion: </strong>CYP intervention was beneficial in improving psychophysiological, autonomic, and biochemical profile of the nurse group of health-care workers.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gunjan Y Trivedi, Soundappan Kathirvel, Kamal Sharma, Banshi Saboo
{"title":"Effect of Various Lengths of Respiration on Heart Rate Variability during Simple Bhramari (Humming).","authors":"Gunjan Y Trivedi, Soundappan Kathirvel, Kamal Sharma, Banshi Saboo","doi":"10.4103/ijoy.ijoy_113_23","DOIUrl":"10.4103/ijoy.ijoy_113_23","url":null,"abstract":"<p><strong>Background: </strong>Heart rate varies during breathing and the heart rate variability (HRV) facilitates the autonomic homeostatic capacity. The maximum HRV was observed at around 10 s of prolonged respiration as per HRV biofeedback literature. However, there is a gap in understanding the variations in HRV by different respiration lengths during simple Bhramari practice.</p><p><strong>Objective: </strong>To assess the effect of various respiration lengths (8, 10, 12, and 14 s) on HRV during the simple Bhramari (humming) practice.</p><p><strong>Methodology: </strong>A total of 118 individuals (67 males, 51 females) signed up for the study based on convenience sampling at a wellness center. A randomized (simple permutation) within-subject crossover design with repeated measures was used to measure their HRV during the simple Bhramari practice. The results were analyzed with one-way ANOVA and paired samples <i>t</i>-test.</p><p><strong>Results: </strong>The results indicate that, unlike the 10 s of respiration during HRV biofeedback breathing, maximum HRV during humming happens between 12 and 14 s of long breathing.</p><p><strong>Conclusions: </strong>The unique findings of the study demonstrate the maximization of HRV between the respiration lengths of 12 and 14 s. Future work should explore expanding the research to a broader group of participants, including individuals with chronic conditions and other demographic variables and mantra chanting.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Study to Evaluate the Effect of a Combined Approach of Yoga and Diet in High-risk Cardiovascular Subjects.","authors":"Aayushee Rao, Sudhanshu Kacker, Neha Saboo","doi":"10.4103/ijoy.ijoy_71_23","DOIUrl":"10.4103/ijoy.ijoy_71_23","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular disease (CVD) is a group of disorders of the heart and blood vessels, including coronary heart disease, cerebrovascular disease, rheumatic heart disease, peripheral artery disease, congenital heart disease, deep vein thrombosis, and pulmonary embolism.</p><p><strong>Aim: </strong>The aim of this study was to assess cardiovascular risk factors and evaluate the effectiveness of combined approach of yoga and diet in reducing cardiovascular risk factors among high-risk subjects.</p><p><strong>Materials and methods: </strong>This interventional study was conducted at RUHS College of Medical Sciences and Associated Hospitals, Jaipur, on the high-risk population of either sex in the age group of 40-70 years. QRISK3 web calculator was used as the method of measurement for outcome of interest. The combined approach of yoga intervention includes yogic asanas and pranayamas and dietary modification.</p><p><strong>Results: </strong>This study compared physiological parameters (blood pressure) and biochemical parameters (fasting blood sugar, glycosylated hemoglobin, lipid profile) at baseline, three months and six months after yoga and diet intervention in participants who were at high-risk of cardiovascular disease development in future and were found to be having significantly decreased systolic blood pressure (<i>P</i>=0.000), fasting blood glucose (<i>P</i>=0.000), glycosylated hemoglobin (HbA1C) (<i>P</i>=0.011), total cholesterol-high density lipoprotein ratio (<i>P</i>=0.000), low density lipoprotein (<i>P</i>=0.009), triglyceride (<i>P</i>=0.034), and QRISK3 Score (<i>P</i>=0.000) after combined approach of yoga and diet.</p><p><strong>Conclusions: </strong>This study concluded that the short-term combined approach of yoga-based life-style intervention and diet reduced cardiovascular risk factors in subjects at high-risk of developing cardiovascular disease.</p>","PeriodicalId":14436,"journal":{"name":"International Journal of Yoga","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10775843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}