International Journal of Veterinary Medicine最新文献

{"title":"The effect of liposomal feed additives on the provision of vitamin A and carotene in cows","authors":"R. M. Khomenko, V. V. Alexandrov, S. Safronov","doi":"10.52419/issn2072-2419.2023.4.190","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.190","url":null,"abstract":"In conditions of industrial milk production, it is important to provide livestock with complete  feed,  including  all  the  necessary nutrients  to  meet  the  needs  of  a  lactating cow. Active metabolic processes and intense activity of the cow’s entire body during lactation  are  a  prerequisite  for  increasing  its need  for  vitamins.  Currently,  various  feed additives and premixes are used in feeding dairy cows, enriching the animals’ diet with essential vitamins, but their productive effect is  contradictory.  The  conducted  studies  established the positive effect of the liposomal additive “LipoCar” on meeting the need for β-carotene  and  vitamin  A  in  the  body  of cows  during  lactation.  Introduction  of  the feed additive “LipoCar” into the main diet in the amount of 6 g/cow/day. helps normalize the  vitamin  nutrition  of  cows,  especially during the transit period. This is confirmed by the results of studies of the blood serum of cows before and after the use of the LipoCar feed additive. In the control group, the content of vitamin A in the blood serum of cows was 2.4 times higher and corresponded to the physiological norm, compared to the control  group,  where  this  indicator  did  not correspond to the norm. There was a positive trend  in  the  content  of  β-carotene  in  the blood  serum  of  cows  in  the  experimental group, with an increase of 4.4 times by the end  of  the  study  compared  to  the  control group. The results obtained allow us to recommend the use of the LipoCar feed additive in the diets of cows from the first day after  calving  in  an  amount  of  6  g/head.  1 time per day for 30 days to normalize metabolism  and  increase  resistance  in  lactating cow.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"2 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139006814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elimination of 1,3,7-trimethylxanthine in laboratory animals during the induction of fatty hepatosis","authors":"O. Popova, V. S. Ponamarev, A. Kostrova, L. Agafonova","doi":"10.52419/issn2072-2419.2023.4.179","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.179","url":null,"abstract":"Liver pathologies play a significant role in changing the metabolism and clearance of a  number  of  pharmacologically  active  substances,  including  1,3,7-trimethylxanthine, which is explained by their influence on enzyme systems that regulate the biotransformation of exogenous biologically active substances. Currently, changes in caffeine clearance  are  being  actively  studied  in  various hepatobiliary disorders, especially those that are chronic, since it is precisely such pathologies, according to a number of researchers, that are characterized by the most predictable  and  stable  change  in  the  trimethylxanthine  pharmacokinetic  profile.  The  purpose of  the  study  was  to  determine  changes  in serum  caffeine  levels  when  inducing  fatty liver  disease  in  laboratory  animals  (rats). The studies were carried out in the vivarium of  the  Department  of  Pharmacology  and Toxicology  of  the  Federal  State  Budgetary Educational Institution of Higher Education of St. Petersburg State University of Medicine.  Laboratory  animals  from  a  previous series of experiments were selected for the study  in  order  to  further  compare  the “caffeine curves.” Fatty hepatosis was modeled using strontium sulfate according to the methodology  developed  at  the  Department of  Pharmacology  and  Toxicology.  Upon completion of induction, fatty hepatosis was confirmed based on clinical and biochemical signs.  Based  on  the  studies  conducted,  we can conclude that there are certain correlations.  For  example,  in  fatty  hepatosis,  the elimination  of  caffeine  is  not  significantly slowed down with a characteristic long plateau (up to 8 hours after administration), turning into a smooth decrease in concentration. Experimental  data  can  be  used  to  create  a database to assess the relationship between pharmacokinetics and the physiological state of animals. Similar experiments need to be carried out on other animal species, which will create a holistic picture and help in assessing  pathologies  for  veterinary  specialists.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"12 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138977024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring of the epizootic situation of tick infestation in the territory of Stavropol","authors":"D. Proskurin, O. V. Dilekova","doi":"10.52419/issn2072-2419.2023.4.117","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.117","url":null,"abstract":"This problem is also relevant for urbanized  cases,  especially  for  the  southern  regions of the country, where there are cases of spread of ticks. Research on the basis of the Department  of  Parasitology  and  Veterinary and Sanitary Expertise, Anatomy and Pathology named after prof. S. N. Nikolsky and the Scientific, Diagnostic and Treatment Veterinary Center of the FGBOU HE \"Stavropol State Agrarian University\", as well as on the basis  of  the  veterinary  clinic  IP  Zaichenko \"Veterinary  Center  named  after.  Pirogov. The object of the study was ixodid ticks of the genera Dermacentor and Ixodes, seized using  a  specialized  trap,  as  well  as  seized with  dogs  in  veterinary  clinics  during  the acceptance. The study showed that two main types of ixodid ticks are widespread in the city  of  Stavropol:  Demacentor  and  Ixodes. According to the results of research in 2022, female ticks of the genus Dermacentor identified  54%  of  the  total  number  of  adults, males - 46%. Female ticks of the genus Ixodes accounted for 61% of the total number of adults, males - 39%. The spring peak of activity in 2023 showed that female ticks of the genus Dermacentor were identified in the amount of 102 individuals, males - 78 individuals.  Female  ticks  of  the  genus  Ixodes accounted  for  53%  of  the  total  number  of adults, males - 47%. Thus, it has been established that the most widespread distribution of ixodid ticks takes place in the Industrial District of Stavropol, the distribution of alleys, forest zones and walking areas with the coverage of the species of ticks of the genus Dermacentor, is 79% of the total number of captured ectoparasites.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"38 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138981011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of various drugs on the growth rate of sterlet larvae","authors":"S. V. Kuzmicheva, D. Mikryakov, D. A. Novikov, S. R. Salov","doi":"10.52419/issn2072-2419.2023.4.126","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.126","url":null,"abstract":"An  experimental  study  of  the  effect  of various  feed  additives  on  the  rate  of  mass accumulation,  growth  rate  and  survival  of sterlet larvae was carried out. Four groups of fish  were  planted  in  flowthrough  plastic pools with 150 fish each. The control group (I) was fed without additives, while the experimental group was fed with the addition of  different  preparations:  II -  preparation \"AQUATAN\"  based  on  ellagotannins  produced  by  the  company  \"Tanin\",  Sevnica, Slovenia. Sevnica (Slovenia) at the rate of 2 g/kg  of  feed,  III - antibacterial  preparation based on ciprofloxacin \"Antibak-100\" (LLC \"NVTs Agrovetzaschita\"), at the rate of 0.5 g/kg live weight of fish, IV - probiotic based on  Bacillus  subtilis  \"SUB-PRO\"  (LLC \"Vector-Euro\")  at  the  rate  of  100  g/t  feed. The preparations were added to the feed according  to  the  instructions.  The  effect  of preparations on fish was evaluated by fishery indicators: average daily growth rate, absolute  growth,  average  daily  gain  and  mass accumulation coefficient. During the experiment it was found that the values of fishery indicators  in  different  groups  of  sterlet changed  with  different  intensity  depending on the time after the beginning of the experiment. The highest growth rate and mass accumulation  rates  were  recorded  in  fish  fed with  SUB-PRO  and  Antibak-100,  and  the lowest  with  Aquatan.  The  results  obtained indicate the expediency of further studies of the effect of various preparations on the fishery parameters of aquaculture objects aquaculture.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"20 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138979995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphofunctional changes in the reproductive organs of females against the background of the use of a phytopreparation (experimental study)","authors":"T. Boyko, I. V. Ogurnoy, M. V. Koshkarev","doi":"10.52419/issn2072-2419.2023.4.133","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.133","url":null,"abstract":"The  paper  presents  the  results  of  the assessment of morphological changes in the uterus  and  ovaries  of  laboratory  animals against the background of the introduction of therapeutic doses of a multifunctional phytopreparation, which includes alcohol extracts from  plants:  white  hellebore  (Veratrum  album),  dioecious  nettle  (Urtica  dioica),  yarrow  (Millefolii  herba)  and  has  rumination, uterotonic, hemostatic and anti-inflammatory effects.  Therapeutic  doses  for  cows  were tested, which for rats amounted to 0.2 ml per head.  The  phytopreparation  was  adminitered subcutaneously three times, every other day. The control group rats were subcutaneously injected with a saline solution of sodium  chloride  (NaCI  0.9%)  according  to  the same  scheme.  The  methods  of  digital  microscopy were used  in the  study of micropreparations.  Morphometric  analysis  of  the histoarchitectonics  of  the  uterus  revealed  a statistically significant increase in the diameter of the cross-section of the uterus of female  rats  of  the  experimental  group  by 25.8%  (p≤0.05) compared  with  the  control group due to an increase in the epithelial by 24.5% (p≤0.05) and the endometrial lamina of  the  uterine  mucosa  by  32%  (p≤0.05), which indicates on increasing the secretory activity of the epithelial cover of the uterus. In  the  experimental  group  of  rats  treated with phytopreparation, a significant increase of 46% (p<0.05) in the number of primordial follicles was noted. There was also a tendency to increase the number of primary – by 36.3%, secondary – by 41.7%, tertiary – by 75%  of  follicles  and  yellow  bodies –  by 22.2%  in  rats  of  the  experimental  group compared with the control indicators.  Quantitative indicators of the follicular composition of the ovaries of rats of the experimental group and an increase in  the follicle aging coefficient by 60% (p≤0.05) indicate stimulation  of  the  ovarian  reserve  against  the background of the use of phytopreparation.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"212 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139010154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An immunochromatographic test for the detection of anti-tuberculosis antibodies","authors":"N. I. Khammadov, K. S. Khaertynov, R. M. Akhmadeev, R. I. Shangaraev, K. V. Usoltcev, A. I. Khamidullina, A. Galeeva","doi":"10.52419/issn2072-2419.2023.4.14","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.14","url":null,"abstract":"Tuberculosis is a dangerous socially significant  disease  of  various  animal  species. According  to  Rosselkhoznadzor  data  for 2022, the situation with bovine tuberculosis is endemic, stable, long-term trends are decreasing,  epidemic  thresholds  for  ill  health and  incidence  have  not  been  overcome.  It should be noted that in 2022, bovine tuberculosis was not officially detected, but this infection was registered in several pigs and wild boars. Take a point that the reduction in the number of cases of tuberculosis in cattle is decreased (to zero), the overall strategy for combating this disease is successful, but this does not mean that the need to develop new tests  for  the  accelerated  diagnosis  of  this infection  has  completely  disappeared.  The safety of service personnel directly depends on  minimizing  the  risk  of  infection  with pathogens common to humans and animals, one of which is tuberculosis. The fastest way to indicate infectious agents is by immunochromatographic  analysis.  This  publication is devoted to the details that it is desirable to focus on when developing a diagnostic test based on immunochromatographic analysis, using the example of bovine tuberculosis. As an antigen in the presented study, native antigens of Mycobacterium bovis grown on a nutrient  medium  Levenshtein-Jensen  with proven antigenic activity were used. Conjugation of antispecies antibodies was carried out  with  a  colloidal  solution  of  gold, (diameter  of  particle  is  25±0,9  nm).  In  the course  of  the  work,  the  optimal  conditions for the manufacture of a diagnostic test for the detection of anti-tuberculosis antibodies by  immunochromatographic  analysis  were shown.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"73 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138982410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of the level of compartmentalization on the export potential of the region, in the context of the Novosibirsk and Tomsk regions","authors":"M. A. Senina, K. I. Krivetsky, E. V. Arkhipenko","doi":"10.52419/issn2072-2419.2023.4.49","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.49","url":null,"abstract":"The formation of the level of zoosanitary protection  of  enterprises  is  reflected  in  the assignment  of  the  status  of  regionalization for  especially  dangerous  animal  diseases throughout the country. The Federal Service for  Veterinary  and  Phytosanitary  Surveillance ensures the safety of the territory of the Russian  Federation  from  the  introduction and spread of animal diseases. Assigning the level  of  compartmentalization  to  an  enterprise depends on compliance with the basic standards for the maintenance and breeding of  pigs,  as  well  as  the  processing  of  pig products. The assignment of the highest level of compartmentalization allows the company  to  sell  products  almost  without  restrictions, both within the subject of the Russian  Federation  and  between  subjects,  as well  as  for  export.  The  emergence  of  outbreaks of particularly dangerous diseases not only  in  Russia,  but  also  around  the  world causes  great  social  and  economic  damage. The World Organization for Animal Health is  developing  principles  for  ensuring  the biological  safety  of  the  territory.  Carrying out  preventive,  diagnostic  and  therapeutic measures at enterprises form an increase in the level of zoosanitary protection and ensuring the safety of the spread of the disease. The topic of the article is new and relevant today, since the level of compartmentalization of enterprises in the region confirms the zoosanitary status of the territory. The export of  meat  products  from  the  territory  of  the region depends on a number of factors, including  the  assigned  status  of  regionalization.  Increasing  the  export  potential  of  the region depends on the interaction of authorities  and  enterprises.  The  fulfillment  of  the conditions of the importing countries is the most important principle of export supplies. Many enterprises are deprived of the right to export only because of the formal approach of fulfilling the requirements that lead to the identification of violations during the preparation of export shipments and the certification  of  the  enterprise  for  inclusion  in  the registers of compartmentalization.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"112 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138982931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IN VITRO evaluation of probiotic properties and bacteriocinogenic potential of strains of microorganisms L. Acidophilus 13, E. Faecium K-50 and their compositions","authors":"A. I. Zhivoderova, V. S. Samoylenko","doi":"10.52419/issn2072-2419.2023.4.78","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.78","url":null,"abstract":"It is known that the gut microbiota plays a central role in the health and biology of the animal, and is therefore important for scientific research. Microorganisms of the genus Lactobacllus  are  widespread  in  nature  and are considered representatives of the microflora  of  the  macroorganism  of  the  animal. Lactobacllus acidophilus is widely used as a probiotic, and is known for its immunostimulating effect, it colonizes the intestines of a newborn  and  accompanies  the  animal throughout its life. Enterococcus faecium is also used as a probiotic, due to its high antagonistic activity against pathogenic microbiota, and also participates in the formation and maintenance of immunity. The purpose of  this  study  was  to  evaluate  the  probiotic component of L. acidophilus 13, E. faecium k-50  in  conditions  simulating  the  gastrointestinal tract, to study the bacteriocinogenic potential and antagonistic properties of lactobacilli and enterococci and their composition.  In  this  review,  we  summarize  recent advances  in  understanding  the  mechanisms involved in bacterial tolerance to bile, with particular  emphasis  on  research  contributions. In addition, the physiological and ecological role of enzymes and their importance for animal health, as well as the function of bile  acid  as  a  regulator  of metabolism,  are discussed. Samples were used in the study.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138982490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The nature of expression of avian immunity genes during infection with GALLID ALPHAHERPESVIRUS 2 and MELEAGRID ALPHAHERPESVIRUS 1","authors":"N. V. Tarlavin, V. Veretennikov, E. Javadov, D. Kraskov, K. V. Sidorenko, I. Makhnin","doi":"10.52419/issn2072-2419.2023.4.30","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.30","url":null,"abstract":"Marek's disease is a dangerous immunosuppressive  viral  disease  of  poultry.  Most egg poultry farm in the Russian Federation vaccinate their chickens on the first day of life against this viral disease. Thanks to this vaccine prevention tactic, poultry farms protect  themselves  from  the  outbreak  of  this disease and economic damage. Traditionally, among  the  viruses  related  to  this  disease, there are the 1st serotype of the Marek's disease  virus  (Gallid  alphaherpesvirus  2)  and the 3rd serotype of the Marek's disease virus, which is not such in a strict taxonomic sense (Meleagrid  alphaherpesvirus  1,  also  called turkey herpesvirus). When poultry is infected, this virus causes a significant change in the expression of the main immunity genes (IL6,  PTGS2,  IRF7).  Based  on  the  results obtained, it was concluded that the expression of the IL6 and PTGS2 genes was slightly  higher  than  the  level  of  expression  of these genes in the control group. It is possible  that  local immunity  was  suppressed by the  immunosuppressive  properties  of  the Marek's  disease  virus.  When  studying  the expression of the IRF7 gene, a strong effect of viruses of both serotypes on this gene was found,  and  Gallid  alphaherpesvirus  2  exceeded the level of this effect compared to the  effect  of  Meleagrid  alphaherpesvirus  1 by 4 times. These results may indicate that sharply  increasing  expression  of  the  IRF7 gene may be a sign of Marek's disease virus replication (since Gallid alphaherpesvirus 2 and  Meleagrid  alphaherpesvirus  1  interact with the same cellular receptor, the vaccine effect  of  Meleagrid  alphaherpesvirus  1  is based  on  this).  On  the  other  hand,  we  can conclude that the introduction of these viruses does not cause inflammatory and immune reactions in the ileocecal tonsils of birds.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"1128 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138982625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of scientifically based monitoring programs and therapeutic and preventive measures for controlled infectious diseases of animals","authors":"A. Poryvaeva, E. Pechura, O. G. Petrova, N. A. Bezborodova, Y. Lysova, D. A. Belousova","doi":"10.52419/issn2072-2419.2023.4.96","DOIUrl":"https://doi.org/10.52419/issn2072-2419.2023.4.96","url":null,"abstract":"The aim of the work was to assess the effectiveness  of  an  improved  monitoring program  for  controlled  infectious  animal diseases  and  individual  vaccination  programs for acute respiratory viral infection in cattle.  To  fulfill  the  tasks  set,  serological studies, PCR diagnostics, bacteriological and coprological methods of examining biological samples from animals were carried out. As a result of the work, the main factors influencing  the  effectiveness  of  vaccine prophylaxis of acute respiratory viral infection in cattle populations have been identified. It was found that in three administrative and  administrative  districts  of  the  Sverdlovsk region, the main factors in 35.1% of cases are violations of the rules of vaccination  of  acute  respiratory  viral  infection  of cattle, in 13.5% of cases - violations of zoo-hygienic  and  veterinary–sanitary  conditions of keeping farm animals. A comprehensive assessment of the effectiveness of individual vaccination programs for cattle against acute respiratory  viral  infection  has  been  carried out, taking into account the epizootological situation in agricultural organizations. It was shown  that  vaccination  of  cattle  against acute respiratory viral infection according to individual  programs  ensured  the  formation of specific immunity in 92.5-95.0% of animals.  The  number  of  immunotolerant  individuals and animals with a low level of immunoreactivity in the physiological group of young  cattle  did  not  exceed  3.5%,  in  the physiological  group  of  adult  animals  – 1.25%.    The  high  efficiency  of  improved scientifically based programs for monitoring, diagnosis, therapeutic, preventive and health measures  to  protect  animals  from  epizootically significant infectious diseases of cattle among  the  populations  of  farm  animals  of the Ural Federal District has been confirmed.","PeriodicalId":14419,"journal":{"name":"International Journal of Veterinary Medicine","volume":"759 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138982704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}