International Journal of Tuberculosis and Lung Disease最新文献_第9页

Outcomes for people with TB by disease severity at presentation. 按发病时的病情严重程度划分的肺结核患者的治疗结果。

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0254

S V Leavitt, C A Rodriguez, T C Bouton, C R Horsburgh, P Abel Zur Wiesch, B E Nichols, L F White, H E Jenkins

{"title":"Outcomes for people with TB by disease severity at presentation.","authors":"S V Leavitt, C A Rodriguez, T C Bouton, C R Horsburgh, P Abel Zur Wiesch, B E Nichols, L F White, H E Jenkins","doi":"10.5588/ijtld.23.0254","DOIUrl":"10.5588/ijtld.23.0254","url":null,"abstract":"<sec id=\"st1\"><title>BACKGROUND</title>There is substantial heterogeneity in disease presentation for individuals with TB disease, which may correlate with disease outcomes. We estimated disease outcomes by disease severity at presentation among individuals with TB during the pre-chemotherapy era.</sec><sec id=\"st2\"><title>METHODS</title>We extracted data on people with TB enrolled between 1917 and 1948 in the USA, stratified by three disease severity categories at presentation using the U.S. National Tuberculosis Association diagnostic criteria. These criteria were based largely on radiographic findings (\"minimal\", \"moderately advanced\", and \"far advanced\"). We used Bayesian parametric survival analysis to model the survival distribution overall, and by disease severity and Bayesian logistic regression to estimate the severity-level specific natural recovery odds within 3 years.</sec><sec id=\"st3\"><title>RESULTS</title>People with minimal TB at presentation had a 2% (95% CrI 0-11%) probability of TB death within 5 years vs. 40% (95% CrI 15-68) for those with far advanced disease. Individuals with minimal disease had 13.62 times the odds (95% CrI 9.87-19.10) of natural recovery within 3 years vs. those with far advanced disease.</sec><sec id=\"st4\"><title>CONCLUSION</title>Mortality and natural recovery vary by disease severity at presentation. This supports continued work to evaluate individualized (e.g., shortened or longer) regimens based on disease severity at presentation, identified using radiography.</sec>.","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":"28 3","pages":"142-147"},"PeriodicalIF":4.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11075045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140059368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TB and interstitial lung disease: a systematic review and meta-analysis. 肺结核与间质性肺病：系统回顾与荟萃分析。

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0428

M Rezaee, N Azizi, B Danaei, A Davari, S A Nejadghaderi, T Sarmastzadeh, M Rahmannia, F Khalili, A H Shahidi-Bonjar, R Centis, L D'Ambrosio, G Sotgiu, G B Migliori, M J Nasiri

{"title":"TB and interstitial lung disease: a systematic review and meta-analysis.","authors":"M Rezaee, N Azizi, B Danaei, A Davari, S A Nejadghaderi, T Sarmastzadeh, M Rahmannia, F Khalili, A H Shahidi-Bonjar, R Centis, L D'Ambrosio, G Sotgiu, G B Migliori, M J Nasiri","doi":"10.5588/ijtld.23.0428","DOIUrl":"10.5588/ijtld.23.0428","url":null,"abstract":"<sec id=\"st1\"><title>INTRODUCTION</title>To determine the frequency of TB among patients with interstitial lung diseases (ILDs).</sec><sec id=\"st2\"><title>METHODS</title>We performed a comprehensive search in the PubMed/Medline, EMBASE and Scopus databases up to 1 August 2023 of studies reporting on the prevalence of TB among patients with ILDs.</sec><sec id=\"st3\"><title>RESULTS</title>Twelve studies comprising 3,817 patients with ILD were found: the pooled prevalence of TB among ILD patients was 11.0% (95% CI 5.4-21.0). In the subgroup analysis, the TB rate among patients with silicosis and idiopathic pulmonary fibrosis (IPF) was respectively 35.6% (95% CI 32.6-38.8) and 4.4% (95% CI 3.6-5.3) (P = 0.00). The frequency of TB among ILD patients was higher in high TB burden countries than in low/intermediate-burden countries: 26.3%, 95% CI 17.7-37.3 vs. 4.9%, 95% CI 3.3-7.2; P = 0.00.</sec><sec id=\"st4\"><title>CONCLUSIONS</title>This study shows the frequency of TB among ILD patients. The meta-analysis reveals a significantly increased prevalence of TB among ILD patients with silicosis compared to IPF, and among individuals in high TB burden countries than in those with low/intermediate burden. The study results can help physicians and policymakers make efficient decisions for prompt screening and anti-TB treatment initiation in ILD patients.</sec>.","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":"28 3","pages":"130-135"},"PeriodicalIF":4.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140059374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The pressing need for standardised diagnostic criteria for obstructive ventilatory impairment in adults and children. 亟需制定成人和儿童阻塞性通气障碍的标准化诊断标准。

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0510

M Abdesslem, I Ghannouchi, H Ben Saad

引用次数: 0

Therapeutic drug monitoring for isoniazid and rifampicin exposure. 异烟肼和利福平暴露的治疗药物监测。

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0495

C A Peloquin

引用次数: 0

A new understanding of clinical patterns in post-TB lung disease. 对结核病后肺部疾病临床模式的新认识。

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0327

H Thomson, N Baines, T Huisamen, C F N Koegelenberg, E M Irusen, L Mapahla, B W Allwood

{"title":"A new understanding of clinical patterns in post-TB lung disease.","authors":"H Thomson, N Baines, T Huisamen, C F N Koegelenberg, E M Irusen, L Mapahla, B W Allwood","doi":"10.5588/ijtld.23.0327","DOIUrl":"10.5588/ijtld.23.0327","url":null,"abstract":"<sec id=\"st1\"><title>BACKGROUND</title>Post-TB lung disease (PTLD) can be categorised based on physiological, radiological, and clinical abnormalities, delineating distinct clinical patterns; however, thus far the importance of this is unknown. People with PTLD have a high morbidity and increased mortality, but predictors of long-term outcomes are poorly understood.</sec><sec id=\"st2\"><title>METHODS</title>We conducted an observational study of PTLD patients attending a tertiary hospital in South Africa between 1 October 2021 and 30 September 2022. Patient demographics, risk factors, symptoms, lung function tests and outcomes were captured.</sec><sec id=\"st3\"><title>RESULTS</title>A total of 185 patients were included (mean age: 45.2 years, SD ±14.3). Half of patients reported only one previous episode of Mycobacterium tuberculosis infection (n = 94, 50.8%). There was a statistically significant association between TB-associated obstructive lung disease (OLD) and dyspnoea (P = 0.002), chest pain (P = 0.014) and smoking (P = 0.005). There were significant associations between haemoptysis and both cavitation (P = 0.015) and fungal-associated disease (P < 0.001). Six patients (3.2%) died by study end.</sec><sec id=\"st4\"><title>CONCLUSION</title>PTLD can affect young people even with only one previous episode of TB, and carries a high mortality rate. For the first time, clinical patterns have been shown to have meaningful differences; TB-related OLD is associated with dyspnoea, chest pain and smoking; while haemoptysis is associated with cavitary and fungal-associated disease.</sec>.","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":"28 3","pages":"115-121"},"PeriodicalIF":4.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140059363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A structured 2-week follow-up visit in the cascade of care for TB increases case detection. 在结核病级联治疗中进行有组织的 2 周随访可提高病例发现率。

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0435

F Rudolf, E Abate, B Moges, V F Gomes, A M Mendes, A Sifna, H Fekadu, S Bizuneh, C Wejse, T Schön

{"title":"A structured 2-week follow-up visit in the cascade of care for TB increases case detection.","authors":"F Rudolf, E Abate, B Moges, V F Gomes, A M Mendes, A Sifna, H Fekadu, S Bizuneh, C Wejse, T Schön","doi":"10.5588/ijtld.23.0435","DOIUrl":"10.5588/ijtld.23.0435","url":null,"abstract":"<sec id=\"st1\"><title>OBJECTIVES</title>Delayed detection in TB due to structural and diagnostic shortcomings is pivotal for disease transmission, morbidity and mortality. We investigated whether an inclusive screening, followed by a structured clinical follow-up (FU) could improve case-finding.</sec><sec id=\"st2\"><title>METHODS</title>Patients were recruited from health centres in Bissau, Guinea-Bissau, and Gondar, Ethiopia. A routine FU was done at Week 2. If persisting symptoms were found, patients were investigated using chest X-ray (CXR) and Xpert® MTB/RIF, followed by a medical consultation. The main outcome were additional TB patients diagnosed by applying the FU strategy.</sec><sec id=\"st3\"><title>RESULTS</title>Of 3,571 adults, 3,285 (95%) were examined at Week 2 FU, where 2,491 (72%) were asymptomatic. Screening patients presenting with cough >2 weeks alone contributed to the diagnosis of 93 patients (45% of all patients diagnosed here), whereas a TBscore >3 increased this by 18 (9%); adding a Week 2 FU yielded an additional 94 (46%) patients. Among the 794 (24%) with persisting symptoms, 25 were diagnosed using Xpert and 69 at clinical FU, which constituted 46% (94/205) of the total TB patients diagnosed.</sec><sec id=\"st4\"><title>CONCLUSION</title>A Week 2 FU visit, which can be nested into routine healthcare, increased the diagnosis of TB patients by two-fold and avoids diagnostic gaps in the cascade-of-care.</sec>.","PeriodicalId":14411,"journal":{"name":"International Journal of Tuberculosis and Lung Disease","volume":"28 3","pages":"148-153"},"PeriodicalIF":4.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140059364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patterns of TB transmission in the United States, 2011-2017. 2011-2017 年美国结核病传播模式。

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0422

K Yamkovoy, J L Self, H E Jenkins, C R Horsburgh, L F White

引用次数: 0

Differentiated TB care: Tamil Nadu's achievements, plans and implications for national TB programmes. 差异化结核病护理：泰米尔纳德邦的成就、计划和对国家结核病计划的影响。

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0297

H D Shewade, A Frederick, K V Suma, R Rao, T S Selvavinayagam, R Ramachandran, M V Murhekar

引用次数: 0

Lower TB notification rates in later life in the same birth cohort, Japan, 1950-2020. 日本 1950-2020 年同一出生组群中晚年结核病感染率较低的情况。

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0092

M Ota, S Hirao, K Uchimura

引用次数: 0

Post-TB lung disease: keep going beyond TB! 结核病后肺部疾病：继续超越结核病！

IF 4 3区医学

International Journal of Tuberculosis and Lung Disease Pub Date : 2024-03-01 DOI: 10.5588/ijtld.23.0588

E Pontali, O W Akkerman, D Zenner, G B Migliori

引用次数: 0