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Forging Ahead: 2023 Updates in Retina. 锐意进取：2023 年视网膜技术更新。
International Ophthalmology Clinics Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.1097/IIO.0000000000000513
Christina Y Weng
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引用次数: 0
Imaging Modalities for Dry Macular Degeneration. 干性黄斑变性的成像模式。
International Ophthalmology Clinics Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.1097/IIO.0000000000000512
Anindya Samanta, Amer F Alsoudi, Ehsan Rahimy, Jay Chhablani, Christina Y Weng
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引用次数: 0
Robotics-assisted Tools in Macular Surgery. 黄斑手术中的机器人辅助工具。
International Ophthalmology Clinics Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.1097/IIO.0000000000000507
Kazuaki Kadonosono, Hiroshi Enaida
{"title":"Robotics-assisted Tools in Macular Surgery.","authors":"Kazuaki Kadonosono, Hiroshi Enaida","doi":"10.1097/IIO.0000000000000507","DOIUrl":"10.1097/IIO.0000000000000507","url":null,"abstract":"","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"64 1","pages":"153-161"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139037661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Nonproliferative Diabetic Retinopathy: Where Do We Stand? 非增生性糖尿病视网膜病变的管理：我们的现状如何？
International Ophthalmology Clinics Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.1097/IIO.0000000000000516
Stephanie M Kaiser, Anshul Bhatnagar, Christina Y Weng
{"title":"Management of Nonproliferative Diabetic Retinopathy: Where Do We Stand?","authors":"Stephanie M Kaiser, Anshul Bhatnagar, Christina Y Weng","doi":"10.1097/IIO.0000000000000516","DOIUrl":"10.1097/IIO.0000000000000516","url":null,"abstract":"","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"64 1","pages":"83-96"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139037659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapies for Geographic Atrophy. 治疗地理萎缩。
International Ophthalmology Clinics Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.1097/IIO.0000000000000515
Suzie A Gasparian, Henry C Skrehot, Christina Y Weng
{"title":"Therapies for Geographic Atrophy.","authors":"Suzie A Gasparian, Henry C Skrehot, Christina Y Weng","doi":"10.1097/IIO.0000000000000515","DOIUrl":"10.1097/IIO.0000000000000515","url":null,"abstract":"","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"64 1","pages":"5-20"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512608/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139037662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Systems Biology Approach Unveils a Critical Role of DPP4 in Upper Gastrointestinal Cancer Patient Outcomes. 系统生物学方法揭示了 DPP4 在上消化道癌症患者预后中的关键作用。
IF 2.1
International Ophthalmology Clinics Pub Date : 2024-01-01 DOI: 10.1615/JEnvironPatholToxicolOncol.2023048056
Sudhir Kotnala, Anupam Dhasmana, Swati Dhasmana, Shafiul Haque, Murali M Yallapu, Manish K Tripathi, Meena Jaggi, Subhash C Chauhan
{"title":"A Systems Biology Approach Unveils a Critical Role of DPP4 in Upper Gastrointestinal Cancer Patient Outcomes.","authors":"Sudhir Kotnala, Anupam Dhasmana, Swati Dhasmana, Shafiul Haque, Murali M Yallapu, Manish K Tripathi, Meena Jaggi, Subhash C Chauhan","doi":"10.1615/JEnvironPatholToxicolOncol.2023048056","DOIUrl":"10.1615/JEnvironPatholToxicolOncol.2023048056","url":null,"abstract":"<p><p>Gastrointestinal (GI) cancers comprise of cancers that affect the digestive system and its accessory organs. The late detection and poor prognosis of GI cancer emphasizes the importance of identifying reliable and precise biomarkers for early diagnosis and prediction of prognosis. The membrane-bound glycoprotein dipeptidyl-peptidase 4 (DPP4), also known as CD26, is ubiquitously expressed and has a wide spectrum of biological roles. The role of DPP4/CD26 in tumor progression in different types of cancers remains elusive. However, the link between DPP4 and tumor-infiltrating cells, as well as its prognostic significance in malignancies, still require further investigation. This study was intended to elucidate the correlation of DPP4 expression and survival along with prognosis, followed by its associated enriched molecular pathways and immune cell marker levels in upper GI cancers. Results demonstrated a strong correlation between increased DPP4 expression and a worse prognosis in esophageal and gastric cancer and the co-expressed common genes with DPP4 were associated with crucial molecular pathways involved in tumorigenesis. Additionally, DPP4 was shown to be significantly linked to several immune infiltrating cell marker genes, including Macrophages (M1, M2 and Tumor Associated Macrophages), neutrophils, Treg, T-cell exhaustion, Th1 and Th2. Overall, our findings suggest that DPP4 may serve as a substantial prognostic biomarker, a possible therapeutic target, as well as it can play a critical role in the regulation of immune cell invasion in patients with gastroesophageal (esophageal, gastroesophageal junction and gastric) cancer. KEY WORDS: DPP4, integrated analysis, GI cancer, gastroesophageal cancer, gastroesophageal junction, prognosis.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"21 2 1","pages":"43-55"},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83540043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydroxychloroquine Screening Guidelines: Best Evidence, Controversies, and Future Areas of Research. 羟氯喹筛查指南：最佳证据、争议和未来研究领域。
International Ophthalmology Clinics Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.1097/IIO.0000000000000508
Alexi Geevarghese, Alexis Kaiser, Sheel Patel, Amit Saxena, Michael H Belmont, Yasha S Modi
{"title":"Hydroxychloroquine Screening Guidelines: Best Evidence, Controversies, and Future Areas of Research.","authors":"Alexi Geevarghese, Alexis Kaiser, Sheel Patel, Amit Saxena, Michael H Belmont, Yasha S Modi","doi":"10.1097/IIO.0000000000000508","DOIUrl":"10.1097/IIO.0000000000000508","url":null,"abstract":"","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"64 1","pages":"195-207"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139037657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in Teleophthalmology Screening for Diabetic Retinopathy. 远程眼科筛查糖尿病视网膜病变的进展。
International Ophthalmology Clinics Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.1097/IIO.0000000000000505
Ailin Song, Durga S Borkar
{"title":"Advances in Teleophthalmology Screening for Diabetic Retinopathy.","authors":"Ailin Song, Durga S Borkar","doi":"10.1097/IIO.0000000000000505","DOIUrl":"10.1097/IIO.0000000000000505","url":null,"abstract":"","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"64 1","pages":"97-113"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139037652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biosimilars for Retinal Diseases: A Review of the Literature. 治疗视网膜疾病的生物仿制药：文献综述。
International Ophthalmology Clinics Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.1097/IIO.0000000000000509
Rachel N Israilevich, Kannan Sharma, Matthew R Starr
{"title":"Biosimilars for Retinal Diseases: A Review of the Literature.","authors":"Rachel N Israilevich, Kannan Sharma, Matthew R Starr","doi":"10.1097/IIO.0000000000000509","DOIUrl":"10.1097/IIO.0000000000000509","url":null,"abstract":"","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"64 1","pages":"129-139"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139037655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Review of Gene Therapy Clinical Trials for Retinal Diseases. 视网膜疾病基因疗法临床试验回顾。
International Ophthalmology Clinics Pub Date : 2024-01-01 Epub Date: 2023-12-26 DOI: 10.1097/IIO.0000000000000517
Aamir A Aziz, Hannah Khan, Zoha A Khanani, Mathew J Thomas, Huma Khan, Abrahim Ahmed, Greggory M Gahn, Arshad M Khanani
{"title":"Review of Gene Therapy Clinical Trials for Retinal Diseases.","authors":"Aamir A Aziz, Hannah Khan, Zoha A Khanani, Mathew J Thomas, Huma Khan, Abrahim Ahmed, Greggory M Gahn, Arshad M Khanani","doi":"10.1097/IIO.0000000000000517","DOIUrl":"10.1097/IIO.0000000000000517","url":null,"abstract":"","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"64 1","pages":"141-151"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139037660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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