发布求助
文献互助 智能选刊 最新文献

International Ophthalmology Clinics最新文献

筛选
英文 中文
Strabismus Surgery in Thyroid Eye Disease. 甲状腺眼病的斜视手术。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000610
Angell Shi, Linda R Dagi
{"title":"Strabismus Surgery in Thyroid Eye Disease.","authors":"Angell Shi, Linda R Dagi","doi":"10.1097/IIO.0000000000000610","DOIUrl":"https://doi.org/10.1097/IIO.0000000000000610","url":null,"abstract":"<p><p>Thyroid eye disease (TED) produces chronic orbital inflammation that may result in restrictive extraocular myopathy and associated diplopia. TED-related strabismus can be challenging to address due to complex and often large-angle deviations, variable surgical results, high rates of reoperation, and profound impact on patients' function and quality of life. We address the evaluation and management of strabismus in TED, and discuss changes that the recent introduction of teprotumumab may have on timing and treatment options previously chosen.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"219-223"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optic Disc Drusen in Children: An Updated Clinical and Imaging Perspective. 儿童视盘囊肿：最新的临床和影像学观点。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000613
Natacha Würtz Yazdanfard, Steffen Hamann
{"title":"Optic Disc Drusen in Children: An Updated Clinical and Imaging Perspective.","authors":"Natacha Würtz Yazdanfard, Steffen Hamann","doi":"10.1097/IIO.0000000000000613","DOIUrl":"https://doi.org/10.1097/IIO.0000000000000613","url":null,"abstract":"<p><strong>Background: </strong>The optic disc in a child with optic disc drusen (ODD) frequently mimics the optic disc in a child with papilledema, which may lead to unnecessary invasive investigations. Recent advances in imaging have transformed our understanding of pediatric ODD.</p><p><strong>Methods: </strong>We reviewed the literature from 2018 to 2025, focusing on pediatric cohorts and novel imaging modalities, including optical coherence tomography (OCT) and OCT angiography (OCTA), and artificial intelligence (AI).</p><p><strong>Results: </strong>Enhanced depth imaging OCT (EDI-OCT) has become the diagnostic reference standard with high sensitivity for detecting both superficial and deep ODD. A peripapillary hyper-reflective ovoid mass-like structure (PHOMS) is reported in up to 90% of children with ODD, in 8.9% of healthy children, and in over 80% of idiopathic intracranial hypertension (IIH) cohorts. A PHOMS primarily reflects optic nerve head crowding and displaced ganglion cell axons. Its high prevalence makes PHOMS a frequent confounder in the evaluation of pediatric optic disc elevation, emphasizing the importance of multimodal imaging. In addition, OCT-based deep-learning algorithms are emerging to enhance diagnostic accuracy, whereas fundus-photo-based algorithms have shown strong performance in differentiating buried ODD from mild papilledema.</p><p><strong>Conclusions: </strong>Recent imaging technologies and longitudinal data have reframed pediatric ODD as dynamic lesions with measurable progression. Integration of OCT, OCTA, and AI-with awareness of PHOMS as a frequent and confounding finding-supports accurate diagnosis, risk stratification, and structured follow-up while reducing unnecessary invasive testing.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"115-125"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on Cerebral/Cortical Visual Impairment (CVI) in Children. 儿童脑/皮质视力障碍（CVI）的最新进展。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000603
Mark J Phillips, Melinda Y Chang
{"title":"Update on Cerebral/Cortical Visual Impairment (CVI) in Children.","authors":"Mark J Phillips, Melinda Y Chang","doi":"10.1097/IIO.0000000000000603","DOIUrl":"https://doi.org/10.1097/IIO.0000000000000603","url":null,"abstract":"<p><p>Cerebral/cortical visual impairment (CVI) occurs when there are abnormalities of visual function and functional vision due to neurological conditions that affect the post-geniculate visual pathways in the brain, while the ocular anatomy is normal or insufficient to explain the degree of visual dysfunction. CVI is a leading cause of pediatric visual impairment in low-, middle-, and high-resource countries, and its increasing incidence is commonly associated with increased survival of premature neonates. We present an overview of CVI definitions, etiologies, diagnostic strategies, methods to assess visual function and functional vision, and considerations for management in the context of a multidisciplinary team. We conclude with an update on current CVI research.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"68-77"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Updates in Amblyopia Treatment Outcomes Through the Lens of Health Disparities. 从健康差异看弱视治疗结果的最新进展。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000606
Candice Medina, Isdin Oke, Eric D Gaier
{"title":"Updates in Amblyopia Treatment Outcomes Through the Lens of Health Disparities.","authors":"Candice Medina, Isdin Oke, Eric D Gaier","doi":"10.1097/IIO.0000000000000606","DOIUrl":"10.1097/IIO.0000000000000606","url":null,"abstract":"<p><p>Amblyopia, the leading cause of monocular vision impairment in children, is a treatable condition when identified early. Despite advancements in nonsurgical therapies-including patching, atropine penalization, and emerging digital tools-significant disparities persist in who receives timely diagnosis and effective treatment. This commentary explores the intersection of amblyopia treatment and health disparities, synthesizing current evidence on how race, socioeconomic status, insurance coverage, age of diagnosis, and geography influence diagnosis, treatment, and outcomes. A keyword-based search across PubMed and Embase revealed a stark underrepresentation of disparities-focused research within the broader amblyopia literature. While recent studies suggest growing awareness, disparities persist in early detection, access to specialists, and treatment efficacy-particularly among children with public insurance, racial and ethnic minorities, and those in underserved regions. This review highlights key themes: early diagnosis is a strong predictor of successful treatment, access to screening alone does not ensure equitable care, and equity must be central to research and innovation as the field embraces digital and adult-targeted therapies. To ensure emerging treatments benefit all patients, future research must prioritize representative populations and use frameworks rooted in health equity. Deliberate efforts to address systemic barriers are essential to achieving equitable amblyopia care across the lifespan.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"165-170"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147499018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Myasthenia Gravis. 小儿重症肌无力。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000614
Andrew F Fischer, Jason H Peragallo
{"title":"Pediatric Myasthenia Gravis.","authors":"Andrew F Fischer, Jason H Peragallo","doi":"10.1097/IIO.0000000000000614","DOIUrl":"https://doi.org/10.1097/IIO.0000000000000614","url":null,"abstract":"<p><p>Pediatric myasthenia gravis encompasses a heterogenous group of disorders that cause impaired neuromuscular junction transmission. Patients exhibit a characteristic fatigable weakness that can be life-threatening if respiration is affected. In children, myasthenia gravis can be grouped into 3 subtypes: transient neonatal myasthenia (TNM) arising from transplacental antibody transfer, congenital myasthenic syndromes (CMS) related to genetic defects, and juvenile myasthenia gravis (JMG) caused by antibodies to synaptic components. Diagnostic evaluation combines clinical evaluation with serologic and electrophysiologic studies. The condition is managed medically with acetylcholinesterase inhibitors and immunosuppressive agents. Thymectomy is an important part of the treatment of JMG, and intravenous immunoglobulin (IVIG) and plasma exchange (PLEX) play a role in acute, severe exacerbations. Management of the ophthalmic complications, including strabismus and ptosis, is necessary to prevent permanent vision loss from amblyopia.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"205-210"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital Optic Nerve Anomalies and Associated Systemic Conditions. 先天性视神经异常及相关系统疾病。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000609
Anjalee Chopra, Iftee Shahriar, Arina Nisanova, Marcela Estrada, Nandini Gandhi, Suma P Shankar, Kareem Moussa, Yin A Liu
{"title":"Congenital Optic Nerve Anomalies and Associated Systemic Conditions.","authors":"Anjalee Chopra, Iftee Shahriar, Arina Nisanova, Marcela Estrada, Nandini Gandhi, Suma P Shankar, Kareem Moussa, Yin A Liu","doi":"10.1097/IIO.0000000000000609","DOIUrl":"https://doi.org/10.1097/IIO.0000000000000609","url":null,"abstract":"<p><p>Congenital optic nerve anomalies represent a group of structural malformations that impair vision, increase the risk of ophthalmic complications, and are frequently associated with systemic conditions. We provide a review of major congenital optic disc anomalies, including optic nerve hypoplasia, morning glory disc anomaly, optic disc coloboma, peripapillary staphyloma, persistent fetal vasculature, myelinated nerve fibers, tilted disc syndrome, optic disc pit, papillorenal syndrome, optic disc drusen, and congenital optic disc pigmentation. We will review the definition, epidemiology, pathophysiology, clinical presentation, diagnostic workup, and associated systemic findings. An emphasis is placed on screening and multidisciplinary management aimed at correcting and preserving vision and preventing complications, such as retinal detachment, maculopathy, strabismus, amblyopia, and endocrine disorders. Diagnosis tools, including optical coherence tomography (OCT), B-scan ultrasonography, magnetic resonance imaging (MRI), and computed tomography (CT), are highlighted for their role in screening for these conditions. Many congenital optic nerve anomalies lack a definitive cure, and some conditions are extremely rare and do not have well-defined treatment protocols. However, routine ophthalmic examination, correction of refractive errors, visual surveillance for systemic conditions, and surgical intervention can optimize patient outcomes. Furthermore, multidisciplinary collaboration between ophthalmologists and other physicians, including pediatricians, endocrinologists, neurologists, and geneticists is often needed to facilitate care.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"78-93"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on Pediatric Idiopathic Intracranial Hypertension. 儿童特发性颅内高压最新进展。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000617
Gena Heidary
{"title":"Update on Pediatric Idiopathic Intracranial Hypertension.","authors":"Gena Heidary","doi":"10.1097/IIO.0000000000000617","DOIUrl":"https://doi.org/10.1097/IIO.0000000000000617","url":null,"abstract":"<p><p>Pediatric idiopathic intracranial hypertension or pseudotumor cerebri is a condition characterized by elevated intracranial pressure (ICP) with the potential for irreversible, profound vision loss in the setting of bilateral swelling of the optic nerves or papilledema. Although there is an awareness of the impact of this condition on visual function, data on the risk factors for disease severity, the relevance of pubertal status on disease progression, and the optimal treatment approaches are lacking. Prospective, multicenter studies are needed to develop standardized guidelines for clinical management to maximize visual outcomes. The purpose of this review is to provide an update on the understanding of pediatric IIH, which will consider epidemiology, current diagnostic criteria, management options, and visual outcomes.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"64-67"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Optic Pathway Gliomas: Diagnosis, Management, and Outcomes. 儿童视神经胶质瘤：诊断、处理和结果。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000611
Grace E Forbes, Robert A Avery
{"title":"Pediatric Optic Pathway Gliomas: Diagnosis, Management, and Outcomes.","authors":"Grace E Forbes, Robert A Avery","doi":"10.1097/IIO.0000000000000611","DOIUrl":"10.1097/IIO.0000000000000611","url":null,"abstract":"<p><p>Optic pathway gliomas (OPGs) are the most common brain tumor that pediatric ophthalmologists and neuro-ophthalmologists care for. These low-grade gliomas are found along the anterior portion of the visual pathway and demonstrate unique features in their growth, impact on visual function and response to treatment. The standardized approach to the ophthalmologic evaluation and testing positions the ophthalmologist to play a vital role in the care of these unique tumors. This review will cover the epidemiology, clinical evaluation, treatment and outcomes of OPGs.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"126-139"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13001898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Cranial Nerve Palsies. 小儿脑神经麻痹。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000612
Michael Nguyen, Varat M Ransibrahmanakul, Veeral Shah, Timothy W Winter
{"title":"Pediatric Cranial Nerve Palsies.","authors":"Michael Nguyen, Varat M Ransibrahmanakul, Veeral Shah, Timothy W Winter","doi":"10.1097/IIO.0000000000000612","DOIUrl":"10.1097/IIO.0000000000000612","url":null,"abstract":"<p><p>Cranial nerve palsies in children offer unique challenges distinct from those in adults, and typically arise from congenital, traumatic, neoplastic, or postinfectious inflammatory disease. With rare reports of diplopia, diagnosis depends on indirect signs such as abnormal head posture, strabismus, or abnormal gaze. The oculomotor (III), trochlear (IV), and abducens (VI) nerves follow sometimes long, intricate courses from the brainstem to the target muscle(s) within the orbit. Accurate diagnosis requires integrating anatomic understanding with subtle clinical presentations and imaging findings, and management must emphasize limitations of congenital disease while relying on neural plasticity and adaptive behaviors. Advances in neuroimaging, molecular genetics, and surgical techniques have greatly improved time to diagnosis and treatment outcomes.</p>","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"187-204"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forward: Pediatric Neuro-Ophthalmology. 前沿：小儿神经眼科学。
International Ophthalmology Clinics Pub Date : 2026-04-01 Epub Date: 2026-03-23 DOI: 10.1097/IIO.0000000000000616
Jason H Peragallo
{"title":"Forward: Pediatric Neuro-Ophthalmology.","authors":"Jason H Peragallo","doi":"10.1097/IIO.0000000000000616","DOIUrl":"https://doi.org/10.1097/IIO.0000000000000616","url":null,"abstract":"","PeriodicalId":14338,"journal":{"name":"International Ophthalmology Clinics","volume":"66 2","pages":"63"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147498911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书