International Journal of Science and Healthcare Research最新文献

{"title":"Relugolix, Estradiol, Norethindrone Acetate (40mg+1.0mg+0.5mg), Oral Combination Therapy for Uterine Fibroids (Relugolix) in Premenstrual Women: A Quality Life Perspective","authors":"Aparna Arora, P.R. Kamble, Chetan Singh Chauhan","doi":"10.52403/ijshr.20230350","DOIUrl":"https://doi.org/10.52403/ijshr.20230350","url":null,"abstract":"The following article elucidates the role of oral therapy for uterine fibroids in increasing the quality of life and a better treatment option as compared to the conventional methods, which are operative and may result in infertility. Uterine fibroids are non-cancerous growths (myomas or leiomyomas) also known as Uterine Leiomyomas or Fibromyomas appear in or around the uterus. They can shrink after menopause, exist in adults of reproductive age, and have been connected to oestrogen, however the specific origin is unknown. Uterine fibroids affect about 1 in 3 women, and their prevalence rises with age until menopause, peaking in the forties. In general, symptoms can be categorized as heavy and protracted menstrual bleeding, pelvic pain, and reproductive dysfunction. The triple combination drug is given orally to the patients (once daily as early as possible after menstrual cycle but no later than seven days after menstrual cycle begins) and it can be given for the period of 24 months which is longer duration than its other alternatives like leuprolide (6-12 months) and it effectively resolves Abnormal Uterine Bleeding – Leiomyomata (AUB-L). It will resolve the imbalance of estrogen and progesterone in female body and reduces the side effects such as bone loss due to estrogen imbalance. Being an oral tablet gives it an advantage over other surgical procedures and parenteral dosage forms as it is non-invasive and easy to administer, in small dose, once daily. Keywords: Uterine Fibroids, Health Related Quality of Life, Gonadotropin Releasing Hormone Receptor Antagonist, Combination Therapy, Relugolix.","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Blackburn Exercise with Thoracic Extension Exercises Versus Thoracic Extension Exercise on Postural Hyper Kyphosis and Scapula Position in Young Asymptomatic Individuals - A Comparative Study","authors":"Arslaan Budgujar, Sucheta Golhar, Kiran Jeswani","doi":"10.52403/ijshr.20230352","DOIUrl":"https://doi.org/10.52403/ijshr.20230352","url":null,"abstract":"BACKGROUND: The spine is composed of two types of curvature: kyphosis and lordosis. Postural hyper kyphosis is the most common posture abnormality and can happen at any age. Causes are idiopathic, sedentary lifestyle, impairments, and aging. Abnormal posture has a detrimental effect on articular and muscular structures as it leads to muscular weakness and degenerative changes. It affects the muscular tension around the neck and shoulder; as it shifts the neck forward (muscle tightness) and the shoulder moves more internally, leading the upper back scapular muscle lengthening. This study uses a flexi-curve ruler to measure postural hyper kyphosis and lateral scapula slide test(LSST) to measure scapula distance. The Blackburn protocol is often used for shoulder and scapular impairments; in this study, the protocol is used to manage postural hyper kyphosis as it targets the same muscle groups that are in an altered state. OBJECTIVE: To compare the effect of Blackburn exercise along with thoracic extension exercise versus thoracic extension exercise on postural hyper kyphosis and scapula position in young asymptomatic individuals. METHODS: A comparative study included 70 samples, age between 18 and 28, divided into 2 groups. The degree of kyphosis was measured using a flexi curve ruler (fcr), and scapula distance was measured using a lateral scapula slide test (lsst) at three positions. Intervention was given for six weeks. RESULTS: After 6 weeks of data analysis, Group A's p-value for kyphosis angle is 0.5 and lateral scapula slide test at 0 degree is 0.735, at 45 degree is 0.1992, and at 90 degree is 0.536, showing significant improvement over another group. Conclusion: Blackburn exercises, along with thoracic extension exercises, were found to be effective in reducing the angle of kyphosis in the young population. Keywords: Hyper kyphosis, Flexi curve Ruler, LSST, Blackburn protocol.","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Nurses' Job Satisfaction in India: A Discussion Paper","authors":"Mahendra Kumar, Col Kiron Jeet","doi":"10.52403/ijshr.20230348","DOIUrl":"https://doi.org/10.52403/ijshr.20230348","url":null,"abstract":"This discussion paper aims to explore the factors influencing nurses' job satisfaction in India and its implications for healthcare. Job satisfaction among nurses is crucial for ensuring high-quality patient care and retaining skilled professionals in the healthcare workforce. In India, where the nursing profession plays a vital role in the delivery of healthcare services, understanding and addressing nurses' job satisfaction is of utmost importance. To accomplish this objective, a comprehensive literature review was conducted to identify the key determinants of nurses' job satisfaction in India. The findings reveal that several factors contribute to nurses' job satisfaction, including salary and benefits, working conditions, professional development opportunities, leadership support, and the recognition of their contributions. By shedding light on the factors influencing nurses' job satisfaction in India, this discussion paper provides valuable insights for healthcare policymakers, administrators, and researchers. It underscores the importance of prioritizing nurses' well-being and job satisfaction to foster a resilient and effective healthcare system in India. Further research and collaborative efforts are warranted to develop evidence-based interventions that positively impact nurses' job satisfaction and, ultimately, patient care. Keywords: Nurses, India, Job satisfaction, salary, In-service education","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Atrichia: A Case Report","authors":"Nilesh Dhanaji Kanase, Abhijit Shinde, Suresh Waydande","doi":"10.52403/ijshr.20230356","DOIUrl":"https://doi.org/10.52403/ijshr.20230356","url":null,"abstract":"Introduction: Congenital Atrichia is a rare genetic condition in which all body hair may be absent. Congenital Atrichia is a rare genodermatoses is characterized by a mutation of the human hairless (HR) gene on chromosome 8p22. There is loss of scalp hair between, eyebrow, eyelash, and body hair may also be sparse or absent; patients may have a few pubic and axillary hairs. The condition may present in isolation or along with other defects. There are many forms of inherited alopecia (i.e., hair loss), which vary in age of onset, severity, and associated ectodermal abnormalities. Congenital alopecia universalis or congenital atrichia without associated ectodermal defects is a rare autosomal recessive disorder and is the only form of inherited alopecia for which the molecular basis is known. (2) Case Report: Here is a case report on a preterm neonate delivered via normal vaginal delivery in our hospital setup. Patient was on mechanical ventilator after birth. Patient gradually improved at it was noticed that there was total absence of hair on the body. Dermatology opinion was taken and after few investigations and genetic testing it was confirmed case of Congenital Atrichia due to mutation in chromosome no 8p22. Discussion: Congenital atrichia is a rare disease, causing irreversible alopecia which is inherited autosomal recessively. There is complete irreversible hair loss seen soon after birth. Situs inversus and mesocardia has also been reported to be associated with this disease. Conclusion: Congenital atrichias represent a large and heterogeneous group of inherited hair disorders. In this report, we describe a patient affected with alopecia universalis congenita Keywords: Congenital, atrichia, hairless gene, vitamin d deficiency","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135438545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Motivational Therapy in Dealing with Driving Anger Among Adolescents in Selected Localities of Bhopal, India - A Quasi Experimental Single Group Pretest-Posttest Study","authors":"Sharat V Kondaguli","doi":"10.52403/ijshr.20230351","DOIUrl":"https://doi.org/10.52403/ijshr.20230351","url":null,"abstract":"Purpose: To find out the influence of motivational therapy in dealing with driving anger among adolescent population. Materials and methods: The research design used for this study is Single group pretest-posttest quasi experimental design. Study was conducted in Karond and Bhanpur areas of Bhopal city, India. the duration of the data collection was four weeks. Study population were the 30 adolescents residing in Karond and Bhanpur areas of Bhopal city, India. Sampling technique used was purposive sampling technique. Consent, Ethical clearance was obtained before proceeding for the study. Results: Upon conducting a comparative analysis of the mean pre-test and post-test levels of driving anger within the experimental cohort, a noteworthy observation emerged. Specifically, a substantial mean discrepancy of 21.79 units was discerned between the pre-test and post-test measurements, coupled with a t-value of 18.08. This compellingly indicates the presence of a significant disparity in driving anger levels prior to and subsequent to the implementation of motivational therapy. Conclusion: The imperative to develop anger reduction therapies and techniques is underscored by their potential to ameliorate road rage-related issues and foster the overall well-being of humanity. In the realm of road rage reduction, it is prudent to explore techniques that promote safe and efficacious means of anger management. The individuals participating in this study exhibited diverse underlying causes for their aggressive driving tendencies, often lacking an avenue to address these issues openly. While they harbored intentions to desist from such behavior, the absence of a supportive framework hindered their progress. The present study shines a light on the significance of sustained, authentic, and resolute endeavors aimed at addressing road rage among adolescents, utilizing a structured motivational therapy approach. The outcomes of the study elucidated that the participants grappled with varying degrees of driving-induced anger. Notably, the introduction of structured motivational therapy yielded a discernible reduction in their levels of driving anger, a change substantiated through statistical analysis. Keywords: Driving anger, Adolescents, Motivational Therapy, Road rage.","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"139 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Properties and Characterizations of k-Continuous Functions and k-Open Sets in Topological Spaces","authors":"Ahmed M. Rajab, Hawraa S. Abu Hamd, Eqbal N. Hameed","doi":"10.52403/ijshr.20230355","DOIUrl":"https://doi.org/10.52403/ijshr.20230355","url":null,"abstract":"Topology, a branch of mathematics focused on understanding the fundamental properties of spaces, has experienced a new dimension with the introduction of -open sets. This exploration delves into the realm of -topology, unveiling concepts such as -interior, -closure, -limit points, -continuous functions, and more. Through rigorous definitions, illustrative examples, and a web of theorems, the study navigates the intricate relationships between -open sets and traditional topology. We analyze the interplay of -functions, investigate the properties of -homeomorphisms, and discuss the connections between -totally continuous and -contra-continuous functions. By merging established topology with these novel notions, this study sheds light on the intricate fabric of topological spaces (briefly top. sp. ) from a unique perspective. Keywords: Topological Spaces, Homeomorphisms, Contra-Continuous Functions, Totally Continuous","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135438546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Xanthinuria: A Rare Case Report","authors":"Surbhi Sawant, Suresh Waydande, Abhijit Shinde","doi":"10.52403/ijshr.20230353","DOIUrl":"https://doi.org/10.52403/ijshr.20230353","url":null,"abstract":"INTRODUCTION: Classical xanthinuria is an autosomal recessive hereditary disease which manifests as a result of deficiency of xanthine dehydrogenase which converts hypoxanthine, and xanthine into uric acid. Molybdenum cofactor deficiency, an inherited form of xanthinuria, causes hyperreflexia, microcephaly, and other central nervous system symptoms in newborns. Molybdenum cofactor deficiency, an inherited form of xanthinuria, causes hyperreflexia, microcephaly, and other central nervous system symptoms in newborns. The function of three different enzymes (xanthine dehydrogenase, aldehyde oxidase, and sulfite oxidase) depends on a molybdenum-containing cofactor that is congenitally defective in this disorder. CASE REPORT: A full term female baby born to a G3P1L1A1 mother via normal vaginal delivery was referred from outside hospital on day of life 10 in view of one episode of convulsion on day 3 of life. Baby was screened for inborn errors of metabolism which revealed increased excretion of Xanthine in urine. MRI of brain was done which showed extensive areas of diffusion restriction involving bilateral cerebral hemispheres, bilateral corticospinal tracts and corpus callosum suggestive of Acute hypoxic ischaemic encephalopathy. DISCUSSION: Because of enzymatic deficiency, xanthine dehydrogenase cannot be converted into uric acid which leads to increase in blood levels, and urinary excretion of hypoxanthine, and xanthine. Since these substances have a lower solubility in urine, they accumulate in the urinary system leading to formation of stones. Reduced or undetectable serum uric acid levels associated with MoCD are a result of the deficiency of xanthine dehydrogenase. Most of the patients with classical xanthinuria are asymptomatic, and in 30% of the cases urolithiasis develops. CONCLUSION: Refractory seizures, encephalopathy, and the absence of radiologic signs of HIE a positive family history of perinatal asphyxia, and refractory seizures are contributors in newborn fatalities that demonstrate a significant tendency to develop xanthinuria. A thorough research regarding its prevalence and prognosis should be done. Keywords: xanthinuria, autosomal recessive hereditary disease, newborn","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Stacked Breathing Technique to Reduce Postoperative Pulmonary Complications and Improve Pulmonary Functions: A Brief Review","authors":"Charu Taneja, Suman Mehra, Mahavir Singh Jangra","doi":"10.52403/ijshr.20230349","DOIUrl":"https://doi.org/10.52403/ijshr.20230349","url":null,"abstract":"Patients with postoperative complications have high risk of generating respiratory complications such atelectasis, pneumonia, respiratory dysfunction and pleural effusion. Physiotherapy has been widely used as a means of improving postoperative pulmonary function and reducing complications. Several methods have been studied such as: intermittent positive pressure ventilation, exercises with deep breathing, incentive spirometry and chest physiotherapy. Stacked Breathing is an exercise used to improve the size of breath in one take. This technique is useful when respiratory muscles are weak and when deep breathing can be difficult to breath. Keywords: Stacked Breathing, Postoperative Pulmonary Complications, Pulmonary Functions","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135437618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior Ear Canal Reconstruction by Autologous Cartilage and Flaps in One Stage","authors":"Khaled M Mokbel Khalefa","doi":"10.52403/ijshr.20230331","DOIUrl":"https://doi.org/10.52403/ijshr.20230331","url":null,"abstract":"Background: Reconstruction of the posterior canal wall should be planned by the surgeon in canal wall down mastoidectomy to prevent the resulting cavity that is prone to recurrent infection. The surgeon should choose the type of grafts either autologous, homologous or allografts. Furthermore, the surgeon should decide whether to do immediate reconstruction or delayed one.\u0000Methods: In this study, the ridge was reconstructed at the same time of mastoidectomy by autologous tissues. We used conchal cartilage graft vascularized by pedicled perichondrial and periosteal flaps. The study included 48 patients (32 males and 16 females) with age ranged from 18-55 years. All patients were with unilateral chronic suppurative otitis media with persistent discharge. They had been operated at our tertiary hospital between Jan. 2012 to march 2014\u0000Results: Successful reconstruction was obtained in all cases with no dehiscence, necrosis or canal stenosis\u0000Conclusion: The use of composite conchal cartilage with perichondrial and periosteal flaps in repair of the ridge is highly efficient. The presenting study recommends doing this repair at the same operative time concomitantly with canal wall down mastoidectomy\u0000\u0000Keywords: Mastoidectomy, Cholesteatoma, Cartilage graft, Perichondrium, Periosteum, flaps.","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75565285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Various Conventional Treatments on Plantar Fasciitis: A Brief Review","authors":"Manju, Pradyumna Krishna M, Sameer","doi":"10.52403/ijshr.20230338","DOIUrl":"https://doi.org/10.52403/ijshr.20230338","url":null,"abstract":"Plantar fasciitis is a painful ailment caused by inflammation of the plantar fascia characterised by heel pain. Plantar fasciitis is a degenerative syndrome of the plantar fascia caused by recurrent trauma to the calcaneus. The plantar fascia is a thick, multilayered fibrous connective tissue on the sole of the foot that aids in the creation of the longitudinal arch of the foot. It dynamically stabilises the medial longitudinal arch, restores the arch and helps in reconfiguration of the foot for efficient toe-off. Also, it provides static support to the longitudinal arch as well as dynamic shock absorption. The characteristic PF discomfort is localised around the medial tubercle of the calcaneus and arises after the first few steps in the morning or after a lengthy period of non-weight bearing activities. Standing or walking causes pain and tenderness on the sole of the foot, particularly under the heel.\u0000\u0000Keywords: plantar fasciitis, heel pain, Muscle stretching exercises, gluteal muscle strengthening","PeriodicalId":14300,"journal":{"name":"International Journal of Science and Healthcare Research","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81399570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}