International Journal of Scientific Reports最新文献

{"title":"Prevalence, common clinical presentations and severity patterns of post-dural puncture headache among parturients who underwent cesarean section using spinal anesthesia in western Uganda: a cross-sectional study","authors":"Theoneste Hakizimana, Osman Mohamud Jelle, M. P. S. Ishimwe","doi":"10.18203/issn.2454-2156.intjscirep20233865","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233865","url":null,"abstract":"Background: Post-dural puncture headache is a complication of regional blocks that results from intentional dural puncture during spinal anesthesia and unintentional dural puncture during epidural anesthesia. The aim of the study was to determine the prevalence, common clinical presentations and severity of post-spinal puncture headache among parturients who underwent cesarean section using spinal anesthesia in western Uganda. Methods: A cross-sectional study was conducted on 249 mothers who were consecutively enrolled in their 3rd post-partum day during the period from April 2022 to July 2022 from postnatal ward of Fort portal Regional Referral Hospital. The data needed for analysis was gathered using pretested questionnaires. Data was entered into microsoft excel version 16, coded and transported into SPSS version 22 for analysis. Descriptive statistics was carried out using SPSS version 22.0.    Results: The prevalence of post-dural puncture headache among parturients who underwent cesarean section using spinal anesthesia was 81 (32.5%). Commonest clinical presentation being front/back headache 59 (72.8%), worsened with upright posture 81 (100%), coughing/sneezing 81 (100%) and improved on lying flat position 81 (100%).  The commonest form was mild one 35 (43.2%). Conclusions: This study revealed a high prevalence of post-dural puncture headache as compared to studies done in the region which mainly presented as frontal/back with the commonest form being mild.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"120 23","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139163522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Port site tuberculosis and retained gall stone after laparoscopic cholecystectomy","authors":"Vivek Kumar, Azaz Akhtar Siddiqui, Khriethonuo Kesiezie, Mahak Goel, Arun Kumar, Jenna B. Bhattacharya, Fathima O. V.","doi":"10.18203/issn.2454-2156.intjscirep20233560","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233560","url":null,"abstract":"Laparoscopic cholecystectomy is one of the most common general surgical procedures performed. Port site infection is common surgical site infection. However, tuberculosis of port sites is very uncommon. We report a case of a 36-year-old lady who was presented to our center with complaint of swelling at midclavicular port and seropurulent discharge from epigastrium port site for one month after laparoscopic cholecystectomy done outside. Patient underwent wide local excision with stone retrieval and histopathology of specimen was suggestive of chronic inflammation. Following excision patient again develop swelling at scar site and FNAC from swelling reveal feature of tuberculosis, subsequently patient was started on anti-tubercular drug therapy and follow-up after 2 months show healthy suture line with no sinus or discharge or swelling.  Port site tuberculosis in absence of tuberculosis of gall bladder and abdominal is most likely due to contamination of instrument or dressing by mycobacterium tuberculosis. Diagnosis is made by ZN staining or FNAC or biopsy. Management includes incision and drainage or debridement or wide local excision with anti-tuberculosis medication. Following standardized sterilization procedure is essential for prevention.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139245269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cranium bifidum with meningocele in ruminants: a clinical insight","authors":"Abdulrauf Abdulrasheed, Ibrahim A. Suka, Yahaya B. Lawali, Mukaddas M. Ahmad, Nafiu Abdullahi, Hassan Tukur","doi":"10.18203/issn.2454-2156.intjscirep20233561","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233561","url":null,"abstract":"Cranium bifidum is an incomplete closure of the skull at the suture lines, leaving a space through which the intracranial tissues can protrude. Meningocele is the herniation of the meninges containing cerebrospinal fluid through the cranium bifidum. This congenital defect is attributed to the intake of certain poisonous plants, genetic abnormalities, hereditary factors, malnutrition, bovine viral diarrhea, and others. The obvious clinical sign is a floating saccular protrusion of varied size and volume and is typically associated with cranium bifidum in the frontal or parietal region. Surgical management involves exposing the effective cranial opening and suturing the dura mater in a simple continuous pattern. Prognosis depends on the presence or absence of neurological signs; neurological signs are associated with morphological changes in brain tissue with poor prognosis.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139245079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awareness and willingness to use oral HIV self-test and associated factor among Wollo University Health Science student in North East Ethiopia, 2023","authors":"Mullu Kassa","doi":"10.18203/issn.2454-2156.intjscirep20233558","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233558","url":null,"abstract":"Background: Use of oral HIV self-test is integral part of quality improvement of HIV prevention, care and treatment.  There is no evidence related to awareness and willingness to use oral HIV self-test. The aim of the study was to assess awareness and willingness to use oral HIV self-test and associated factors. Methods: Cross-sectional study was conducted among Wollo University student. The data collection instrument was self-administered questionnaire. Simple random sampling technique was used to select the participant’s proportional to sample size. The final sample size was 373 medical students. SPSS version 26 was used to analyze data and the results were presented by using tables, Pie charts, and histograms. The study was analyzed using binary logistic regression and p value less than 0.25 was entered in Multi-variable logistic regression. Finally, p value less than 0.05 in multi-variable logistic regression was considered as statically significant. Odd ratio measured magnitude of association at 95% confidence interval.   Results: A total of 370 health science student were participated, at response rate of 98%. Prevalence of awareness and willingness among health science student toward use oral HIV self-test were 53 (14.32%) and 253 (68.38), respectively.  Factors such as participating in HIV program (AOR=3.27; CI: 1.30-8.21) and who had recent HIV risk (AOR=3.16; CI; 1.40-7.12) were more likely to had awareness toward oral HIV self-test.  Male student (AOR=1.74; CI; 1.02-2.82), who had recent HIV risk (AOR=3.36; CI: 1.40-8.08), recently tested for HIV (AOR=2.84; CI: 1.17-6.89) and who had STI (AOR=9.02; CI: 2.82-32.12) were more likely to be willingness to use oral HIV self-test in the future. Conclusions: This study showed that willingness to use HIV self-test in future was high. But awareness of HIV self-test is low. It is crucial to prioritize willingness and awareness activities particularly among sex of respondent, recent HIV risk, tested for HIV and STI client.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"25 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139245794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The enactment of the maternity and paternity bill 2019 of Pakistan","authors":"Barka Sajid, Rabeya Farid, Muzainah Tabassum","doi":"10.18203/issn.2454-2156.intjscirep20233562","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233562","url":null,"abstract":"“Parental leave” or “family leave” refers to a sanctioned duration off from work that is granted to both parents, irrespective of gender, to nurture a recently arrived offspring. This comprehensive terminology encompasses maternity, paternity, and adoption leave.  Maternity leave is an expression of honour for the awe-inspiring physical and emotional journey experienced by mothers, simultaneously intertwining with paternity and adoption leave, which shines a spotlight on indispensable contribution of fathers. In 1919, the international labor organization (ILO) was established for the sake of providing women workers their necessary maternity leave rights. As stated in convention no. 183, maternity leave should be of at least 14 weeks or above, whereas recommendation no. 191 highlighted that leave should be of at least 18 weeks. The maternity leave can be further classified into: (a) compulsory maternity leave (CML), encompassing two weeks after birth; (b) Ordinary maternity leave (OML), spanning the initial 26 weeks of maternity leave; (c) additional maternity leave (AML) accommodating the succeeding 26 weeks of leave.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"205 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139246175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Misuse of Ozempic as a drug choice for weight loss, a potential threat","authors":"Uzma Aslam, Sarah Mehboob","doi":"10.18203/issn.2454-2156.intjscirep20233563","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233563","url":null,"abstract":"The 387 million people around the globe are diagnosed with type 2 diabetes mellitus (T2DM). Previously used agents to treat T2DM posed adverse risks of hypoglycaemia and weight gain. Recently, Novo Nordisk, a pharmaceutical company, launched a new drug, Ozempic (Semaglutide), a glucagon-like peptide-1 receptor agonist (GLP-1 RA), which was approved by the US Food and Drug Administration on December 5, 2017. The numerous benefits of Ozempic makes it ideal for treatment of T2DM. Unfortunately, there is now an alarming shortage of Ozempic due to its misuse for weight loss.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139242429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of diagnostic accuracy of latex agglutination test and E-test for the detection of methicillin-resistant Staphylococcus aureus","authors":"Nupur Gupta, M. Jais, Aditi Sharma, P. Shrivastava","doi":"10.18203/issn.2454-2156.intjscirep20233559","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233559","url":null,"abstract":"Background: This study was undertaken to compare the phenotypic methods of latex agglutination test and e-test with polymerase chain reaction for the detection of methicillin-resistant Staphylococcus aureus. Methods: Two hundred pus samples obtained from different clinical disciplines were subjected to the latex agglutination test and minimum inhibitory concentration by e-test (Oxacillin and Vancomycin) as per the standard guidelines. The comparison was made with polymerase chain reaction as the reference test. The diagnostic accuracy of each method was reported in terms of sensitivity, specificity, positive predictive value, and negative predictive value.   Results: The sensitivity of latex agglutination test was found to be 100% whereas e-test for Oxacillin was found to be 96.67% sensitive. Higher specificity for e-test was reported (99.41%) when compared to the latex agglutination test (97.65%). Conclusions: Latex agglutination and e-tests are tests are relatively simpler, rapid, and easy-to-perform methods when compared to polymerase chain reaction. The present study reported high sensitivity and specificity values for both the tests, and therefore supports usage of the stated methods as screening tools for methicillin-resistant S. aureus. However, more multi-centric studies are recommended to precisely determine the diagnostic accuracy of these phenotypic methods.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139242880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Theruptor Novo dressing for an infected diabetic foot ulcer: a case study","authors":"B. Pavan","doi":"10.18203/issn.2454-2156.intjscirep20233532","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233532","url":null,"abstract":"In diabetes mellitus (DM) patients with peripheral neuropathy, the diabetic foot infection (DFI) often begins with a small wound that patients may not easily detect and then progresses to a more complex wound. Diabetic foot ulcer (DFU) is estimated to occur in approximately in 25% of individuals with diabetes in India. The bacterial infection is one of the important cause for the chronicity of DFU and are accountable for the high medical costs as well as affecting patients’ quality of life significantly. Preventing DFU secondary infections is an important function of wound dressing. There are many wound dressings available for DFU, and choosing the right dressing is one of the important parameter in the management and ultimately preventing the limb amputation. In this case, the patient presented with non-healing infected DFU and we used Theruptor Novo dressings for the wound management. The Theruptor Novo dressing was efficient in exudate management and preventing secondary infection which helped in accelerated DFU healing.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":" 45","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135290651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Viral conjunctivitis; a rising threat for Karachites amid Monsoon","authors":"Uzma Aslam, Maheera Khan, Sarah Mehboob","doi":"10.18203/issn.2454-2156.intjscirep20233168","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233168","url":null,"abstract":"Viral conjunctivitis (VC), now renowned as red eye, is the most recent addition to the trend of frequent viral infections amid Karachi's rainy season. Conjunctivitis affects approximately 20-40% of the population worldwide. However, the endemic rise of VC in Karachi is alarming and of great concern.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135414054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The interplay between antidiabetic medications and cancer risk","authors":"Duaa Durrani, Muhammad Hassan, Aimen Zulfikar","doi":"10.18203/issn.2454-2156.intjscirep20233169","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20233169","url":null,"abstract":"Diabetes mellitus (DM) refers to a group of metabolic disorders marked by chronic hyperglycemia. Its primary cause usually involves impaired insulin secretion or impaired insulin action. Its prevalence is escalating globally. Type II DM (T2DM) is becoming more common, and it is expected to afflict 7.7% (439 million) of persons aged 20 to 79 by 2030. Diabetes appears to be linked to an increased risk of a variety of cancers, ranging from a 20 to 30% greater risk of breast or colorectal cancer to a 97% increased chance of intrahepatic cholangiocarcinoma or endometrial cancer. Shared risk factors and potential biochemical pathways have prompted investigations into the effect of antidiabetic medications (ADMs) on cancer risk. We intend to investigate the link between diabetes drugs and cancer development.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"16 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135414073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}