International Journal of Scientific Reports最新文献

Transforming weight measurement: a cutting-edge IoT-enabled smart weight machine for centralized price control of products 重量测量的变革：用于集中控制产品价格的尖端物联网智能重量机

International Journal of Scientific Reports Pub Date : 2024-07-25 DOI: 10.18203/issn.2454-2156.intjscirep20241991

Mohammed Saifuddin Munna, Tuton Chandra Mallick

{"title":"Transforming weight measurement: a cutting-edge IoT-enabled smart weight machine for centralized price control of products","authors":"Mohammed Saifuddin Munna, Tuton Chandra Mallick","doi":"10.18203/issn.2454-2156.intjscirep20241991","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20241991","url":null,"abstract":"Background: With the rapid advancement of machine learning technology, there is a growing interest in integrating it into IoT systems for enhanced functionality. In this study, we propose a SMART Weight Machine system designed to detect, weigh, and price various objects using machine learning techniques.\u0000Methods: Our system utilizes TensorFlow, a machine learning framework, in conjunction with Raspberry Pi for object recognition. Image processing is performed locally on the Raspberry Pi for efficient detection. The system also incorporates MySQL for database management and a WebApp developed using PHP and Laravel for the user interface. \u0000Results: Through our implementation, we achieved significant improvements in speed and accuracy. TensorFlow's compatibility with microcontroller devices like Raspberry Pi enabled swift processing, resulting in a 96% accuracy rate for object detection during our evaluation.\u0000Conclusions: The SMART Weight Machine system demonstrates promising potential for real-world applications. Moving forward, rigorous testing and quality assurance will be conducted to ensure the reliability and accuracy of the system during the development phase.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"105 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141802448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A closer observation of the dedicated responsibilities of nurses at public hospitals in Bangladesh 仔细观察孟加拉国公立医院护士的专职责任

International Journal of Scientific Reports Pub Date : 2024-07-25 DOI: 10.18203/issn.2454-2156.intjscirep20241990

Shahinur Parvin, Murshida, M. A. Rahman, Sharmin Akter Sumi, Stephen Kpekura, Zeshaan Yahaya Haji Mahmood, M. A. Ali

{"title":"A closer observation of the dedicated responsibilities of nurses at public hospitals in Bangladesh","authors":"Shahinur Parvin, Murshida, M. A. Rahman, Sharmin Akter Sumi, Stephen Kpekura, Zeshaan Yahaya Haji Mahmood, M. A. Ali","doi":"10.18203/issn.2454-2156.intjscirep20241990","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20241990","url":null,"abstract":"Background: Nurses are important health caregivers in Bangladesh. They help to improve health-facilities every day and reach it to helpless people. This study aimed to assess the responsibilities of professional nurses in public health hospitals.\u0000Methods: The descriptive cross-sectional study conducted at Rajshahi Medical College (RMCH), Bangladesh from 18 September 2018 to 19 February 2019 included 300 individuals with following inclusion and exclusion criteria. A pre-tested questionnaire was used as a tool for data collection. \u0000Results: Majority of participants age range of 31-40y 46.33%, 41-50y 27%, 20-30y, and 51-60y 19% and 7.67%, respectively. Moreover, Female are 96.33% and males constitute only 7.74%. Based on religion, Muslim 87%, Hindu 10%, Christian 1.67%, and Buddhist 1.33%. Beginning of education, diploma was compared to very few with advanced training for instance Master's and Ph.D. 38.67% nurses were 1-5 years of experience. But only 11 had ≥21 years of experience. A significant portion, 48.02%, had a good level of assessment of patients and 36.67% of individuals excelled at a high level of proficiency. While only 2% showed an inferior level of patient assessment. Improvement of quality care, the majority of respondents 48.33% good, 17.67% excellent, 21.67% average, and 3.33% poor quality care.\u0000Conclusions: Nurses are the key element of the healthcare system. The study outcomes showing their best to provide quality service despite of lack of resources. If the responsible authority has a deep look at this domain, in the future they could make a role model in Bangladesh.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"30 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141803104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A clinical research site pharmacy for the division of AIDS sponsored clinical trials in a low middle income country 为中低收入国家的艾滋病临床试验部门提供临床研究场所药房

International Journal of Scientific Reports Pub Date : 2024-07-25 DOI: 10.18203/issn.2454-2156.intjscirep20241993

Rogers Sekabira, Godwin Murungi, Nigel Okot Kirinya, M. Kisekka, Violet Korutaro, Patricia Ntege Nahirya, A. Kekitiinwa

{"title":"A clinical research site pharmacy for the division of AIDS sponsored clinical trials in a low middle income country","authors":"Rogers Sekabira, Godwin Murungi, Nigel Okot Kirinya, M. Kisekka, Violet Korutaro, Patricia Ntege Nahirya, A. Kekitiinwa","doi":"10.18203/issn.2454-2156.intjscirep20241993","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20241993","url":null,"abstract":"This review article provides information on the role of clinical research site (CRS) Pharmacies in supporting the division of AIDS (DAIDS)-sponsored clinical trials at the CRS, their legislative framework, and how they differ from community pharmacies. These pharmacies are relatively few, and little information is available about their operation, setup, and requirements in low-and middle-income countries (LMICs). The information in this article is pertinent to pharmacy associations and regulators who formulate policies and guidelines and to pharmacy professionals eager to enhance their skills and competencies through knowledge sharing to improve the quality of healthcare services. Moreover, this information is relevant in establishing a CRS pharmacy and understanding its interaction with various administrative and financial institutions. This article provides information on how CRS pharmacies achieve uninterrupted power supply for investigational medicinal products (IMP) throughout the year, the sponsor and regulatory requirements for the CRS pharmacy and the processes for IMP shipment, from its dispensation to the study participants. The article also provides information on quality control and assurance processes for maintaining a CRS pharmacy. CRS pharmacies in LMICs have unique requirements, operations, services, and setups, and regulatory authorities must develop policies and guidelines that align with these distinct features. More so, leveraging the existing CRS pharmacies to disseminate skills and knowledge to trainees, community pharmacies, and other medicine outlets can significantly enhance the quality of health services delivered to the community.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"12 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141804451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rytelo: a novel option for transfusion-dependent anemia in myelodysplastic syndromes Rytelo：治疗骨髓增生异常综合征输血依赖性贫血的新选择

International Journal of Scientific Reports Pub Date : 2024-07-25 DOI: 10.18203/issn.2454-2156.intjscirep20241996

M. H. Shuja, A. F. Abbasi, Firzah Shakil

引用次数: 0

Navigating a paradigm shift; food and drug administration approved Tarlatamab-dlle redefining the landscape of small cell lung cancer therapy 引领范式转变；食品药品管理局批准的 Tarlatamab-dlle 重新定义了小细胞肺癌疗法的格局

International Journal of Scientific Reports Pub Date : 2024-07-25 DOI: 10.18203/issn.2454-2156.intjscirep20241995

Muhammad Hamza Gul, Abdul Baseer Wardak, Aiman Waheed

引用次数: 0

Orthodontic treatment modalities of intrusion: a review 入侵的正畸治疗模式：综述

International Journal of Scientific Reports Pub Date : 2024-07-25 DOI: 10.18203/issn.2454-2156.intjscirep20241994

D. Sharma, Gaurav Thakur, D. Gurung, Amrita Thakur

引用次数: 0

Enhancing competitive advantage through a strategic product ‎portfolio ‎and design for variety in weather radar products 通过战略性产品组合和多样化天气雷达产品设计增强竞争优势

International Journal of Scientific Reports Pub Date : 2024-07-25 DOI: 10.18203/issn.2454-2156.intjscirep20241992

Marzieh Azami, Mahdi Karbasian, Sareh Yousefian

{"title":"Enhancing competitive advantage through a strategic product ‎portfolio ‎and design for variety in weather radar products","authors":"Marzieh Azami, Mahdi Karbasian, Sareh Yousefian","doi":"10.18203/issn.2454-2156.intjscirep20241992","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20241992","url":null,"abstract":"Background: In today's competitive industrial landscape, companies are focusing on developing diverse product portfolios to maintain a competitive edge. This trend has led to the adoption of product portfolio strategies aimed at enhancing customer satisfaction and optimizing resource utilization.\u0000Methods: This study introduces a model to enhance the design of weather radar products by integrating DEMATEL and Goal Programming (GP). The methodology involves identifying key indicators of variety in weather radar design, assessing component interdependencies, and determining component weightage for optimal functionality and cost-effectiveness. \u0000Results: The DEMATEL and GP approach proved effective in optimizing the product family structure for weather radar systems. Key results include the identification and prioritization of variety indicators, evaluation of component interdependencies, and determination of component weightage, resulting in a more precise and operational design.\u0000Conclusions: The proposed model for weather radar variety enhances customer satisfaction, meets market demands, and addresses the challenges of dynamic customer needs. This methodology offers valuable insights into managing product variety and complexity, enabling designers to quickly adapt to evolving customer requirements.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"53 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141804803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Explanation based on thermodynamic parameters regarding effect of sensing film thickness and amount of graphene oxide on sensor performance in aniline, N-phenylglycine and graphene oxide based electrochemical heavy metal ion sensor 基于热力学参数的苯胺、N-苯基甘氨酸和氧化石墨烯电化学重金属离子传感器传感膜厚度和氧化石墨烯用量对传感器性能影响的解释

International Journal of Scientific Reports Pub Date : 2024-06-03 DOI: 10.18203/issn.2454-2156.intjscirep20241592

Kusumita Dutta, Siddhartha Panda

{"title":"Explanation based on thermodynamic parameters regarding effect of sensing film thickness and amount of graphene oxide on sensor performance in aniline, N-phenylglycine and graphene oxide based electrochemical heavy metal ion sensor","authors":"Kusumita Dutta, Siddhartha Panda","doi":"10.18203/issn.2454-2156.intjscirep20241592","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20241592","url":null,"abstract":"Background: To construct a heavy metal ion sensor, selectivity and sensitivity are the key important parameters to be taken care of. In our earlier work, film thickness and amount of graphene oxide (GO) content in a novel composite ANGO, synthesized from aniline, N-phenylglycine and GO was varied and sensing parameters including sensitivity, limit of detection (LOD), thermodynamic parameter which includes -∆Gad and charge transport parameter including barrier width (BW), d, of charge transfer based on Simmon’s model were evaluated and compared and an LOD of 800 ppt for Cd2+ was achieved using square wave voltammetry (SWV) withstanding interference from several ions.\u0000Methods: In this work, thermodynamic factors such as -∆Gad, ∆H, reorganization energy, partition coefficient and solvated ionic radius were used to explain the sensor performance with respect to film thickness and amount of GO. All the parameters were analyzed for different film thicknesses and amount of GO and a correlation was achieved. Finally, effect of electrochemical surface area of different polyaniline-based material on thermodynamic properties of detection process of Cd2+ was studied. \u0000Results: The variation of the thermodynamic properties for Cd2+ sensing with respect to film thickness and amount of GO were examined. Similarly, variation of thermodynamic properties for polyaniline based different sensing materials were examined. Correlation coefficients were developed from the thermodynamic parameters and the d values to explain the underlying mechanism behind improved sensor performance. \u0000Conclusions: This study can provide information on the thermodynamic properties which can be predicted from BW technique. The correlation coefficients would help in designing polyaniline based novel sensing film material with the need of lesser number of experiments.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"111 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141272041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the diagnostic impact of P63, PSA and BCL-2 proteins in premalignant and malignant prostate tissues 评估癌前病变和恶性前列腺组织中 P63、PSA 和 BCL-2 蛋白对诊断的影响

International Journal of Scientific Reports Pub Date : 2024-05-23 DOI: 10.18203/issn.2454-2156.intjscirep20241315

A. C. Ogunlayi, V. Ekundina, Adedapo O. Kehinde, Linus A. Enye, Adegoke O. Aremu

{"title":"Assessing the diagnostic impact of P63, PSA and BCL-2 proteins in premalignant and malignant prostate tissues","authors":"A. C. Ogunlayi, V. Ekundina, Adedapo O. Kehinde, Linus A. Enye, Adegoke O. Aremu","doi":"10.18203/issn.2454-2156.intjscirep20241315","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20241315","url":null,"abstract":"Background: Prostate cancer (CaP) is increasingly becoming a major health issue affecting men as cancer-related fatalities are attributable to the condition. Immunohistochemistry (IHC) diagnostic criteria can help in gene-targeted therapy and help reduce its prevalence. This study is to assess the diagnostic impact of prostate-specific antigen (PSA), P63 and BCL-2 antibodies in CaP.\u0000Method: A case-controlled retrospective study was carried out on eighty (80) prostrate tissue blocks retrieved from the pathology archive of Ekiti State university teaching hospital Ado Ekiti. IHC analysis of the selected antibodies was carried out and also stained with haematoxylin and eosin (H and E) for second opinion and confirmation.\u0000Results: The study showed that all the CaP samples had 100% positivity with varying reactivity to the IHC biomarkers; PSA had 100% positivity and MPR of 94% due to its multiple weaknesses as a biomarker p63 is a basal cells marker.\u0000Conclusions: The expressions of these antibodies were observed in the progression of CaP. Although these markers are useful in predicting the progression from benign prostatic hyperplasia (BPH) to CaP, none of them can be utilised in isolation to a conclusion. Hence, they should be used in conjunction with one another to make up for their limitations. The immunohistochemical markers are beneficial in CaP diagnosis.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"28 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141106481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zilucoplan: a novel therapeutic approach to treat generalized myasthenia gravis 齐鲁珂兰：治疗全身性肌无力症的新疗法

International Journal of Scientific Reports Pub Date : 2024-05-23 DOI: 10.18203/issn.2454-2156.intjscirep20241320

Fatima Laique, Sameen Mukhtar, Mubashir Mohiuddin

{"title":"Zilucoplan: a novel therapeutic approach to treat generalized myasthenia gravis","authors":"Fatima Laique, Sameen Mukhtar, Mubashir Mohiuddin","doi":"10.18203/issn.2454-2156.intjscirep20241320","DOIUrl":"https://doi.org/10.18203/issn.2454-2156.intjscirep20241320","url":null,"abstract":"Myasthenia gravis (MG) is an autoimmune neuromuscular disease characterized by muscle weakness due to autoantibodies targeting the neuromuscular junction (NMJ). Zilucoplan, a novel complement inhibitor, has shown promise in managing generalized MG (gMG) by blocking the terminal complement cascade. This article provides an overview of Zilucoplan's pharmacological properties, including its mechanism of action, pharmacokinetics, and pharmacodynamics. Clinical trials, including a phase 3 trial (RAISE), have demonstrated Zilucoplan's efficacy in improving muscle strength and function, as measured by the MG-ADL (MG-activities of daily life) score, compared to placebo. The safety profile of Zilucoplan is favorable, with injection-site reactions being the most common adverse event. Notably, Zilucoplan effectively inhibits both wild-type and clinical C5 variants, expanding its potential utility for patients who do not respond well to existing treatments. While further research is needed to assess its long-term safety and efficacy, Zilucoplan represents a valuable addition to the therapeutic armamentarium for managing gMG.","PeriodicalId":14297,"journal":{"name":"International Journal of Scientific Reports","volume":"23 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141104568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0