International Journal of Research in Pharmaceutical Sciences最新文献_第3页

An insight into the little-known, menacing facts of autoimmune disorder 洞察鲜为人知、来势汹汹的自身免疫性疾病真相

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-11-20 DOI: 10.26452/ijrps.v14i4.4479

Selvi G

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Flipped Classroom – A novel breakthrough in learning 翻转课堂——学习的新突破

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-10-21 DOI: 10.26452/ijrps.v9i4.4454

None Deepak Nallaswamy, None Vishnu Priya V, None Gayathri R

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Pharmacovigilance in Saudi Arabia: A Narrative Review on Adverse Drug Reaction Reporting 沙特阿拉伯的药物警戒:药物不良反应报告的叙述性回顾

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-10-17 DOI: 10.26452/ijrps.v14i4.4452

Hana J. Al Khabbaz

{"title":"Pharmacovigilance in Saudi Arabia: A Narrative Review on Adverse Drug Reaction Reporting","authors":"Hana J. Al Khabbaz","doi":"10.26452/ijrps.v14i4.4452","DOIUrl":"https://doi.org/10.26452/ijrps.v14i4.4452","url":null,"abstract":"Adverse drug reaction (ADR) reporting is an important aspect of pharmacovigilance (PV) in ensuring drug safety during the post-marketing surveillance phase. Currently, the National Pharmacovigilance Center (NPC) established by the Saudi Food and Drug Authority (SFDA) is the regulatory authority receiving ADR reports in Saudi Arabia. Spontaneous ADR reports from healthcare professionals and the public are received by the NPC through an electronic platform known as the Saudi Vigilance System. Signal analysis of the received ADR reports aids the decision-making initiatives related to the reported drugs. Stakeholders’ contribution to ADR reporting, and implementation of effective electronic platforms are important factors affecting the national PV performance. The concept of stakeholders reporting on ADR is relatively new in Saudi Arabia, especially to the public. In this narrative review the national studies describing the stakeholders’ knowledge, perception and barriers toward ADR reporting, and the incidence of ADR reporting by healthcare institutions in Saudi Arabia were evaluated. The findings indicate that more efforts are needed by the SFDA to educate stakeholders about the importance of ADR reporting. The study recommends ADR electronic systems integration between the SFDA and healthcare institutions to improve the frequency and quality of ADR reports, and regular feedback on decisions made about ADR reports should be provided by the SFDA to stakeholders to improve their awareness of the importance of ADR reporting and enhance their contribution to PV and ADR reporting process.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136032475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Antibacterial Activity of Various Solvent Extracts of Leaves of Raphunus sativus 莴苣叶各种溶剂提取物的抑菌活性研究

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-10-06 DOI: 10.26452/ijrps.v14i4.4448

Noor Mohamed M, Parameswari M, Pavithra B, Naveen Kumar S, Nirmal Kumar P, Jothirani P

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Drug Utilization Pattern and Role of Clinical Pharmacist in Medication Adherence of Stroke Patients in a Tertiary Care Hospital, South India: A Prospective Observational Study 药物使用模式和临床药师在印度南部三级医院脑卒中患者服药依从性中的作用:一项前瞻性观察研究

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-08-19 DOI: 10.26452/ijrps.v14i3.4310

M. C., Hasna P, Nayana Km, Jassim M, Aparna Ks

{"title":"Drug Utilization Pattern and Role of Clinical Pharmacist in Medication Adherence of Stroke Patients in a Tertiary Care Hospital, South India: A Prospective Observational Study","authors":"M. C., Hasna P, Nayana Km, Jassim M, Aparna Ks","doi":"10.26452/ijrps.v14i3.4310","DOIUrl":"https://doi.org/10.26452/ijrps.v14i3.4310","url":null,"abstract":"Stroke comprises of a broad term encompassing many disorders of the blood vessels of the central nervous system that may result from either inadequate blood flow to the brain with subsequent infarction of the involved portion of the CNS or haemorrhages into the parenchyma or subarachnoid space of the CNS causing neurologic dysfunction. Stroke is one of the major cause of mortality worldwide. The objective of the study was to assess the drug utilization pattern (DUP) and to evaluate the impact of counseling on medication adherence for stroke patient admitted in the hospital. Dual antiplatelet therapy (69.4%) was mostly given over monotherapy (28.2%). CCB (28.2%) was the most commonly prescribed antihypertensive drug class and amlodipine (77.1%) was the major CCB given in this study. 96.5 prescriptions comply AHA/ASA guidelines. Unintentional reasons for nonadherence were been reported more frequently than intentional reasons prior to the counseling. The commonest reported unintentional reasons were Forgetfulness (96.0%), Confusion (80.0%) and intentional reasons are carelessness (92%), avoiding dosing schedule (78%). Medication adherence before and after counseling was compared and was found to be improved with a statistically significant (p","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79302939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytochemical and Hepatoprotective Activity of Prosopis juliflora Barks on Different Models 黄豆树皮在不同模型上的植物化学和保肝活性

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-08-16 DOI: 10.26452/ijrps.v14i3.4308

Hemamalini K, Sadanandam Palle, Kanakam Vijayabhaskar, Supraja U

引用次数: 0

Evaluation of the total antioxidant capacity, total polyphenol content, and flavonoids content in ethanolic fruit extract of Raphia hookeri and determination of the correlation between the antioxidant effects and the phytochemical contents 测定了钩藤果实乙醇提取物的总抗氧化能力、总多酚含量和总黄酮含量，并测定了其抗氧化作用与植物化学成分含量的关系

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-08-11 DOI: 10.26452/ijrps.v14i3.4306

Akighir J, Yakubu O E, Imo C, Ojogbane E, Owuna R I, Jato J A

{"title":"Evaluation of the total antioxidant capacity, total polyphenol content, and flavonoids content in ethanolic fruit extract of Raphia hookeri and determination of the correlation between the antioxidant effects and the phytochemical contents","authors":"Akighir J, Yakubu O E, Imo C, Ojogbane E, Owuna R I, Jato J A","doi":"10.26452/ijrps.v14i3.4306","DOIUrl":"https://doi.org/10.26452/ijrps.v14i3.4306","url":null,"abstract":"In order to assess the total antioxidant capacity (TAC), total polyphenol content (TPC), and total flavonoid content (TFC) in ethanol fruit extract, as well as to ascertain the relationship between the antioxidant effects and phytochemical levels, this study looked at all three variables. 11 groups of 10 rats each were formed out of the experimental animals. All experimental subjects received a single intraperitoneal injection of aluminium chloride, 4.2 mg/kg body weight. Groups 4 and 5 received n-hexane fraction at 10 and 20 mg/kg b. w., respectively, whereas the other groups received various fractions and crude extracts of R. hookeri. Ethyl acetate fraction was given to groups 6 and 7 at doses of 10 and 20 mg/kg b. w. Aqueous fractions at 10 and 20 mg/kg b. w. were given to groups 8 and 9. While groups 10 and 11 got ethanolic crude extract daily for 21 days at doses of 200 mg/kg b. w. and 400 mg/kg b. w., respectively. All groups that were given AlCl3 - induced TBARS showed a significant (P 0.05) increase in vivo antioxidant activity. However, in the liver, kidney, and testes of all treatment groups, superoxide dismutase (SOD) and catalase (CAT) activity considerably increased (P 0.05). This suggests that a significant portion of the antioxidant activity displayed by the ethanolic fruit extract of R. hookeri is due to flavonoids.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89709304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gender Determination by Using Left Foot Index in Rajasthan Adults 用左脚指数测定拉贾斯坦邦成年人的性别

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-08-09 DOI: 10.26452/ijrps.v14i3.4302

Nupur Shukla, Monika Gupta

引用次数: 0

Descriptive and Retrospective Study on the Prevalence of Overweight and Obesity among Patients with Type 2 Diabetes Mellitus 2型糖尿病患者超重和肥胖患病率的描述性和回顾性研究

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-08-01 DOI: 10.26452/ijrps.v14i3.4301

Samera S, Jayaprakash S, J. K, Bharathi P, Suryaprakash R

{"title":"Descriptive and Retrospective Study on the Prevalence of Overweight and Obesity among Patients with Type 2 Diabetes Mellitus","authors":"Samera S, Jayaprakash S, J. K, Bharathi P, Suryaprakash R","doi":"10.26452/ijrps.v14i3.4301","DOIUrl":"https://doi.org/10.26452/ijrps.v14i3.4301","url":null,"abstract":"Weight gain has been declared as one of the top 10 global health risks by the World Health Organization (WHO). In the past few decades, obesity has increased alarmingly around the world. Most patients with type 1 diabetes possess anti-insulin antibodies before receiving insulin therapy. About 80% of patients with type 1 diabetes have circulating islet cell antibodies. Both developed and developing countries are facing a medical disaster due to obesity. The incidence of type 2 diabetes is correlated with insulin resistance. Insulin resistance does not lead to hyperglycemia in most obese individuals. The purpose of this study is to determine whether Type 2 diabetes mellitus patients are overweight or obese, and to identify risk factors for such disease. Preventing diabetes complications and reducing its prevalence. A study was conducted to determine whether obesity increases the risk of diabetes. Identify dyslipidemia in Type 2 diabetics by studying its prevalence pattern. The age range of 40 to 70 years for type 2 diabetes mellitus patients. The study also excluded participants with dyslipidemia. Various metabolic parameters were measured as well as baseline anthropometric indices (BMI, WHR). We found 25 patients in normal weight category, 3 patients in underweight category, 50 patients in overweight category, and 53 patients in obese category among the patients aged 40-50 years. Developing appropriate and controlled strategies for improving nutrition and promoting weight loss is urgently needed to mitigate Type 2 diabetes patients' increasing health challenges.","PeriodicalId":14285,"journal":{"name":"International Journal of Research in Pharmaceutical Sciences","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87372263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Test 测试

International Journal of Research in Pharmaceutical Sciences Pub Date : 2023-06-30 DOI: 10.26452/ijrps.v14i2.4286

Anandh A

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