E. Nugroho, R. Muslim, I. Riwanto, Soetojo Wirjo Pranoto
{"title":"The Efficacy of Dutasteride and Green Tea Combination Towards Angiogenesis and Bleeding on BPH after TURP : Study their effect on VEGF, MVD and Hb","authors":"E. Nugroho, R. Muslim, I. Riwanto, Soetojo Wirjo Pranoto","doi":"10.12777/IJSE.9.2.80-84","DOIUrl":"https://doi.org/10.12777/IJSE.9.2.80-84","url":null,"abstract":"ABSTRACT Objectives: to find the efficacy dutasteride and green tea in reducing hemorrhage on TURP patients and to evaluate the anti- angiogenesis effect. Methods: Double Blind Randomized Controlled Trial Post Test Only, with 80 samples, randomized into 4 groups: 1 control group and 3 treatment groups (P1 with 0.5 mg of dutasteride, P2 with a capsul of green tea, and P3 with combination of 0.5 mg dutasteride and a capsul green tea at least 14 days before TURP. We compared the ΔHb define the VEGF expression and MVD count to evaluate the angiogenesis changes between 4 groups. The difference is considered statistically significant with p < .05. Results: ΔHb (-0.40 + 0.246) pg/ml for control group, (-0.20 + 0.067) pg/ml for P1 group, (-0.18 + 0.081) pg/ml for P2 group, and (-0.14 + 0.092) pg/ml for P3 group. VEGF expression were (20.20 + 17.386), (12.90 + 15.509), (11.60 + 9.121), and (3.60 + 1.667) for control, P1, P2, and P3 group respectively. MVD count were (41.20 + 10.273), (32.75 + 9.318), (26.15 + 7.278), and (18.35 + 7.876) for control, P1, P2, and P3 group respectively. The result from between-subject effect tests showed statistically significant differences in ΔHb (p<0.001), VEGF expression (p<0.001), and MVD count (p<0.001). Dutasteride and green tea significantly reduce the hemorrhage during TURP by decreasing the MVD. Conclusion : Administration of 0.5 mg dutasteride and 725 mg of green tea, 14 days prior to TURP significantly reduce the hemorrhage during TURP (Δ Hb) by decreasing the MVD","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"9 1","pages":"80-84"},"PeriodicalIF":0.0,"publicationDate":"2015-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66731636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis Loading Height of HTR (High Temperature Reactor) Core to Obtain Criticlity of Reactor","authors":"E. Setiawati","doi":"10.12777/IJSE.9.2","DOIUrl":"https://doi.org/10.12777/IJSE.9.2","url":null,"abstract":"High temperatur reactor (HTR) attract to be studied due to it has inherent safety characteristics and capabilities to produce energy economically. Design of reactor core in this study is a blend HTR 10 in China with HTR pebble-bed. The reactor has thermal power of 10 MW with inlet and outlet helium temperatures of 250 o C and 700 o C. HTR design is a cylindrical with helium gas as a coolant and graphite as a moderator. The HTR uses pebble-bed fuel composed a large amount of particles of TRISO in graphite metrics. Kernel radius used to analyse reactor core height in this research is 225 µm with enrichment of 16% in order to achieve critical condition. Reactor criticality is also influenced by the height of active reactor core where pebble-bed fuel is distributed. Calculation of the reactor criticality at any height variations active core is done with MCNP5 modelling techniques. The modelling is done by making the geometry of reactor and pebble-bed which is distributed by using body-centred cubic lattice in the reactor core. From the MCNP5 calculation, the first criticality of HTR can be achieved on the active core height of 150.9012 cm calculated from the bottom active core with criticality value of 1.00312±0.00090. The higher active reactor core is, the more increasing the reactor criticality is. This is occured due to there are many fuel balls of pebble-bed used, so that activity of fission in reactor increases. However, reactor criticality is still in stable condition in each the rise of active core height from critical core height even though reactor reactivity increases 0.01 Δk/k. The minimum of fuel needed to achieve initial criticality (critical core height) is 11,805 pebbles and 8,906 moderators.","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"9 1","pages":"113-116"},"PeriodicalIF":0.0,"publicationDate":"2015-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66731509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Properties of Carbon Black from Jatropha Seed Shell as A Potential Source of Filler Enhancement in Biocomposites","authors":"N. A. S. Aprilia, H. Khalil, A. Amin","doi":"10.12777/IJSE.10.2.58-62","DOIUrl":"https://doi.org/10.12777/IJSE.10.2.58-62","url":null,"abstract":"The use of biomass as filler in biocomposites are becoming widespread in the present decade because its variety of advantages. Jatropha (jatropha curcas L) seed shell after separated from kernel can be used to produce carbon black because of its higher carbon content, and have the potentiality to use as reinforcement in composites. In this study, carbon black was produced from jatropha seed shell by carbonization in furnace method for 1 hour at 600 o C. Thermo gravimetric analysis to analyze seed shell of jatropha as raw material. The morphological properties of the carbon black were analyzed by elemental analysis by X-ray (EDX), SEM, TEM, XRD, SEM, and TEM. It was found that the yield of carbon black was 40% which included 4 different sizes ranging from 70 – 300 mesh in distribution of particle size analysis. Carbon black suggested that it could be a good filler or reinforcement in biocomposites","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"10 1","pages":"58-62"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66721108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Measurement of cement’s particle size distribution by the buoyancy weighing-bar method","authors":"R. Tambun, N. Pratama, F. Hanum","doi":"10.12777/IJSE.10.2.74-77","DOIUrl":"https://doi.org/10.12777/IJSE.10.2.74-77","url":null,"abstract":"One of the important characteristics of cement quality is particle size distribution. There are several simple methods to measure the particle size distribution of cement based on the Stokes diameter, like Andreasen pipette method, sedimentation balance method, centrifugal sedimentation method, etc. A major disadvantages of these methods are they are time consuming process and require special skills. Particle size distribution also can be analyzed by using a different principle through microscopy, laser diffraction/scattering methods and Coulter counter method. Even these methods produce highly accurate results within a shorter time, however, the equipments are expensive. In the present study, it has developed a new method to overcome the problem. The method is the buoyancy weighing-bar method. This method is a simple and cost-effective. The principle of the buoyancy weighing-bar method that the density change in a suspension due to particle migration is measured by weighing buoyancy against a weighing–bar hung in the suspension, and the particle size distribution is calculated using the length of the weighing-bar and the time–course change in the the apparent mass of the weighing–bar. This apparatus consists of an analytical balance with a hook for underfloor weighing, and a weighing–bar, which is used to detect the density change in suspension. The result obtained show that the buoyancy weighing–bar method is suitable for measuring the particle size distribution of cement, and the result is comparable to that of determined by settling balance method.","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"10 1","pages":"74-77"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66721233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ASAP: Firefox OS之裝置自動化狀態調整APP ASAP","authors":"黃詩豪, 林朝興, 洪健哲, 吳承翰, 洗鈺淇","doi":"10.6159/IJSE.2015.(5-3).03","DOIUrl":"https://doi.org/10.6159/IJSE.2015.(5-3).03","url":null,"abstract":"Most of applications (APP) for automatic status adjustment on mobile phone have been implemented for Android and IOS systems. In this work, we specifically develop the APP called ASAP to import such a functionality to the promising Firefox OS. Firefox OS has been developed by Mozilla in recent years, using web APIs to directly communicate with the core of the operating system and the underneath hardware of a mobile phone. In ASAP, the automatic status adjustment is achieved by system monitoring with scenario scripts. When the condition of a certain script is met, the corresponding pre-defined activities are executed to instantly alter the status of a mobile phone. There are six conditions and six activities defined in the scenario, and the satisfaction of one condition can trig multiple activities to execute. In addition to listening the activity events, we also use a timer to periodically scan the pre-defined scenario scripts to trig the activities. The experimental results show that the ASAP can successfully trig the corresponding activities when a pre-defined scenario is detected.","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"5 1","pages":"23-33"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71316036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non Oblivious Watermarking Technique for JPEG2000 Compressed Images Using Arnold Scrambling of Unequal Size Watermark Blocks","authors":"Geeta Kasana, Kulbir Singh, S. S. Bhatia","doi":"10.12777/IJSE.9.1","DOIUrl":"https://doi.org/10.12777/IJSE.9.1","url":null,"abstract":"In this paper, a watermarking technique for JPEG 2000 compressed image is proposed. Scrambling of secret message is performed block-wise using Arnold Transform. Secret message is divided into non-overlapping blocks of unequal size and then Arnold transform is applied on each block and secret key is generated based on the periodicity of each block. Scrambled secret message is embedded into qualified significant wavelet coefficients of a cover image. After embedding the secret message into wavelet coefficients, the remaining processes of JPEG 2000 standard are executed to compress the watermarked image at different compression rates. Scaling Factor ( SF ) is used to embed watermark into wavelet coefficients and the value of SF is stored into COM box of the code stream of JPEG 2000 compressed image and this SF value and secret key are used to extract the embedded watermark on the receiver side. The performance of the proposed technique is robust to a variety of attacks like image cropping, salt and pepper noise, and rotation. Proposed technique is compared with the existing watermarking techniques for JPEG 2000 compressed images to show its effectiveness.","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"9 1","pages":"17-26"},"PeriodicalIF":0.0,"publicationDate":"2015-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66731362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md. Anisur Rahman, S. Waheed, Md. Ahsan Habib, A. Bahar
{"title":"Six-Correction Logic (SCL) Gates in Quantum-dot Cellular Automata (QCA)","authors":"Md. Anisur Rahman, S. Waheed, Md. Ahsan Habib, A. Bahar","doi":"10.12777/ijse.9.1.9-12","DOIUrl":"https://doi.org/10.12777/ijse.9.1.9-12","url":null,"abstract":"Quantum Dot Cellular Automata (QCA) is a promising nanotechnology in Quantum electronics for its ultra low power consumption, faster speed and small size features . It has significant advantages over the Complementary Metal–Oxide–Semiconductor (CMOS) technology. This paper present , a novel QCA representation of Six-Correction Logic (SCL) gate based on QCA logic gates: the Maj 3 , Maj AND gate and Maj OR. In order to design and verify the functionality of the proposed layout, QCADesigner a familiar QCA simulator has been employed. The simulation results confirm correctness of the claims and its usefulness in designing a digital circuits.","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"9 1","pages":"9-12"},"PeriodicalIF":0.0,"publicationDate":"2015-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66731443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dual solutions for MHD stagnation-point flow of a nanofluid over a stretching surface with induced magneticfield","authors":"Sandeep Naramgari, C. Sulochana","doi":"10.12777/IJSE.9.1.1-8","DOIUrl":"https://doi.org/10.12777/IJSE.9.1.1-8","url":null,"abstract":"Present study deals with the buoyancy-driven MHD mixed convection stagnation-point flow, heat and mass transfer of a nanofluid over a non-isothermal stretching sheet in presence of induced magneticfield, radiation, chemical reaction, suction/injection and heat source/sink. The basic governing partial differential equations are reduced to a set of ordinary differential equations by using appropriate similarity transformation. The resulting system is solved numerically by bvp5c Matlab package. Numerical results are validated by comparing with the published results. The influence of non-dimensional governing parameters on velocity, induced magneticfield, temperature and concentration profiles along with coefficient of skin friction, local Nusselt and Sherwood numbers are discussed and presented with the help of graphs and tables. Comparisons are made with the existed studies. Results indicate that dual solutions exists only for certain range of suction/ injection parameter and injection parameter have tendency to enhance the momentum, thermal and concentration boundary layer thickness.","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"9 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2015-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66731740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of fluoxetine on macrophage function in chronic pain (Experimental study in Balb/c mice)","authors":"D. Pudjonarko, E. Dharmana, O. Hartanto","doi":"10.12777/IJSE.9.1.27-33","DOIUrl":"https://doi.org/10.12777/IJSE.9.1.27-33","url":null,"abstract":"Chronic pain raises stress conditions such as depression that can lower the cellular immunity. Fluoxetine is an antidepressant used as an adjuvant in pain management but no one has been linked it with the body immune system. The objectives of this research were to p roof the benefits of fluoxetine in preventing degradation of macrophage function in chronic pain by measuring the macrophage phagocytic index , macrophage NO levels and the liver bacterial count in BALB/c mice infected with Listeria Monocytogenes.A Post Test - Only Control Group Design was conducted using 28 male mice strain BALB /c, age 8-10 weeks. The control group (C), mice got the same standard feed as the other groups. Chronic pain group (P), mice were injected with 20μL intraplantar CFA on day-1. Pain + fluoxetine early group (PFE) were treated with P + fluoxetine 5 mg / kg ip day-1, the 4th, the 7th and the 10th, while the Pain + fluoxetine late group (PFL) were treated with P + fluoxetine 5 mg / kg ip on day 7th and 10th. All mice were injected with 104 live Listeria monocytogenes iv on day 8th. Termination was performed on day 13th. Differences within groups were analyzed using One-way ANOVA and Kruskall Wallis, whereas the correlation of variables were analyzed using Pearson's product momen t. The experimental results showed that The macrophage phagocytic index and NO macrophage level (pg/mL) in PFE group(2,24±1,013; 0,24±0,239) was higher than than P group (1,68±0,920; 0,21±0,263) and there was no different in the macrophage phagocytic index of PFE group compared to C group (p=0,583; p=0,805). I n PFL group (4,32±1,459; 0,54±0,294) the macrophage phagocytic index as well as NO macrophage level (pg/mL) was higher than P group (1,68±0,920; 0,21±0,263) with p=0,002; p=0,017. P group Bacterial count (log cfu/gram) (2,30±0,849) was significantly higher than C group(1,15±0,223) (p=0,007), while PFE group bacterial count (1,96±0,653) and PFL group bacterial count (1,84±0,403) compared to C (1,15± 0,223) was not significantly different (p=0,093; p=0,220). Correlation found between macrophage phagocytic index and macrophage NO (r=0,515, p=0,005).Macrophage phagocytic index and macrophage NO showed no correlation with bacterial count (r=-0,051, p=0,798; r=-0,071, p=0,719).It can be concluded that f luoxetine significantly incerases macrophage phagocytosis index and macrophages NO level in mice with chronic pain, on the other hand fluoxetine decreases liver bacterial count . There is a positive correlation between macrophage phagocytosis index and macrophages NO level, while no correlation observed among two variables with mice liver bacterial count in chronic pain.","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"9 1","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2015-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66731379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation of Folic Intake and Internal Carotid Artery Intima-Media Thickness Changes In Post Ischemic Stroke Patients","authors":"D. Tugasworo, D. Pudjonarko, Latifah Latifah","doi":"10.12777/IJSE.8.2.159-166","DOIUrl":"https://doi.org/10.12777/IJSE.8.2.159-166","url":null,"abstract":"The thickness of the carotid artery intima media / intima-media thickness (IMT) is one of atherosclerosis markers. Atherosclerosis is one of the causes of ischemic stroke. Some studies suggest that low folate intake is predicted to affect the atherosclerotic process, but this remains controversial. Our objective is to analyze the relationship between folate intake with changes in the internal carotid artery IMT after ischemic stroke patients.The study is one group pretest posttest design with 72 post ischemic stroke subjects from neurology polyclinic of Kariadi Hospital, from June to December 2013. Folate intake was measured by Food Frequency Questionnaire and the internal carotid artery IMT by duplex ultrasonography. Measurements were taken at two periods with 6 months interval. Other factors that affect atherosclerosis consisting of age, obesity, hypertension, dyslipidemia, diabetes mellitus. The analysis in this study using Spearman correlation, chi-square and logistic regression. Resultwas significant if the p value were <0.05.There were 44 male subjects (61.1%) and 28 female subjects (38.9%). The mean age was 61.6 (SD = 7.99) years. The mean intake of folate was 178.10 (SD = 38.875) mg / day. Median serum folic acid level 8.43 (4.96 to 55.01) NML / L. The mean change in ICA IMT was 0.10 (SD = 0.156) mm. Folate intake was not correlated with serum levels of folic acid. Serum folic acid levels are not correlated with changes in the internal carotid artery IMT. There was correlation between the risk factors of age, BMI, hypertension, diabetes and dyslipidemia with changes in the internal carotid artery IMT.","PeriodicalId":14209,"journal":{"name":"International Journal of Science and Engineering","volume":"8 1","pages":"159-166"},"PeriodicalIF":0.0,"publicationDate":"2015-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66730969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}