1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451)最新文献_第3页

Nitric oxide (NO) in brain: - detection by voltammetric methods - role in a rat model of absence epilepsy 脑内一氧化氮(NO): -伏安法检测-在缺失癫痫大鼠模型中的作用

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893773

H. Faradji, C. Rousset, S. Gautier-Sauvigné, R. Cespuglio

{"title":"Nitric oxide (NO) in brain: - detection by voltammetric methods - role in a rat model of absence epilepsy","authors":"H. Faradji, C. Rousset, S. Gautier-Sauvigné, R. Cespuglio","doi":"10.1109/MMB.2000.893773","DOIUrl":"https://doi.org/10.1109/MMB.2000.893773","url":null,"abstract":"The multiplicity of the functional aspects in which nitric oxide (NO) is involved, is now well documented. As yet, however, only a limited number of studies deal with a direct detection of NO in vivo. In the present paper, a procedure allowing such measurement by mean of a carbon fiber sensor coated with porphyrin-nickel and nafion is detailed. The effects of a NOS inhibitor and a NO donor on the cortical NO signal of the Wistar rat are also reported. In this respect, the disappearance of the signal observed after inhibition of the NO-synthase (L-ANA) as well as its increase after the administration of a NO donor (SIN-1) support that the signal measured at a 650 mV potential is NO dependent. Finally, the results obtained in using the NO sensor in GAERS rats (Genetic Absence Epileptic Rat from Strasbourg, an animal model for absence epilepsy) are briefly summarised. Data obtained indicate that NO exerts an antiepileptic role in facilitating paradoxical sleep. It is concluded that the NO sensor prepared can be efficiently used in vivo in physiological and pathophysiological situations.","PeriodicalId":141999,"journal":{"name":"1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451)","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124871059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Porous silicon as a therapeutic biomaterial 多孔硅作为治疗性生物材料

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893752

L. Canham

引用次数: 20

Optical detection of molecular beacons in microfluidic devices 微流控装置中分子信标的光学检测

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893820

M. Balberg, K. Hristova, D. Brady, D. Beebe, L. Raskin

引用次数: 5

Design and simulation of a dielectrophoretic-based microsystem for bioparticle handling 生物颗粒处理介电泳微系统的设计与模拟

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893821

F. Fernández-Morales, J. Samitier, O. Ruiz, J. Bausells, Errachid Abdelhamid

{"title":"Design and simulation of a dielectrophoretic-based microsystem for bioparticle handling","authors":"F. Fernández-Morales, J. Samitier, O. Ruiz, J. Bausells, Errachid Abdelhamid","doi":"10.1109/MMB.2000.893821","DOIUrl":"https://doi.org/10.1109/MMB.2000.893821","url":null,"abstract":"Nowadays, handling of biological objects at the single-cell level is one of the most active and important research fields. To achieve this goal dimensions of the required tools must roughly match those of the bioparticles at issue, usually ranging from 1 to 100 /spl mu/m. The objective of this paper consists of presenting a microsystem designed for particle microhandling. Some results with polystyrene microspheres are also presented. The operating principle of the aforementioned microsystem hinges upon dielectrophoresis (DEP), which is defined as the lateral motion of electrically neutral matter under the influence of non-uniform electric fields. In practice, the device was fabricated on a silicon substrate onto which interdigitated castellated microelectrodes made of platinum were patterned by lift-off. Moreover, the substrate was micromachined utilising TMAH to anisotropically etch the silicon wafer. Microchamber walls were patterned by PDMS, a photocurable resin which allows a constant sample volume when performing the experiments.","PeriodicalId":141999,"journal":{"name":"1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125174429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Catheter navigation system for intravascular use 导管导航系统用于血管内使用

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893780

D. Tanase, J. Goosen, P.J. Trimp, J. Reekers, P. French

引用次数: 7

Monitoring of the aggregation phase of erythrocyte sedimentation rate by impedance method on micrometric scale 用阻抗法在微米尺度上监测红细胞沉降率聚集期

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893811

V. Tvarozek, G. Krausko, R. Záhorec, I. Novotný, V. Rehacek

引用次数: 2

Micro implantable visual prostheses 微型植入式视觉假体

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893826

M. Schwarz, L. Ewe, N. Hijazi, B. Hosticka, J. Huppertz, S. Kolnsberg, W. Mokwa, H. Trieu

引用次数: 14

Microchips as implantable drug delivery devices 微芯片作为植入式药物输送装置

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893831

R. Scheidt, J. Santini, A. C. Richards, A. M. Johnson, A. Rosenberg, M. Cima, R. Langer

引用次数: 14

Phase contrast microscopy on cultured endothelial cells as alarm system for toxic agents 培养内皮细胞作为毒物报警系统的相衬显微镜研究

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893739

A. Abdelghani, C. Abdelghani, G. Chmel, E. Sackmann

引用次数: 1

Development of small size data logger to observe marine animals 研制小型海洋动物观测数据记录仪

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893757

H. Muramoto, Y. Naito

引用次数: 4