1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451)最新文献_第10页

An RF-telemetry system with shape memory alloy microelectrodes for neural recording of freely moving insects 一种形状记忆合金微电极射频遥测系统，用于自由运动昆虫的神经记录

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893833

S. Takeuchi, I. Shimoyama

{"title":"An RF-telemetry system with shape memory alloy microelectrodes for neural recording of freely moving insects","authors":"S. Takeuchi, I. Shimoyama","doi":"10.1109/MMB.2000.893833","DOIUrl":"https://doi.org/10.1109/MMB.2000.893833","url":null,"abstract":"A radio frequency (RF) telemetry system with a shape memory alloy (SMA) microelectrode was designed and fabricated. The total size and weight are respectively 15 mm/spl times/8 mm and 0.1 g, without a battery. Since the telemeter is small and light enough to be loaded on a small animal such as an insect with no restraint on motion, the system can be used for the neural recording of a freely moving insect. The SMA microelectrode, fabricated by using microelectromechanical systems (MEMS) technologies, can be easily attached to a nerve by electrically actuating the electrode structure, Moreover, it does not detach from the nerve during the insect's motion due to its clipping structure. The telemeter can transmit signals by frequency modulation (FM) transmission at 80/spl sim/90 MHz. The transmitted signals can be received up to about 16 m away from the telemeter with a high S/N ratio. The neural activity can be detected without attenuation by using an instrumentation amplifier with its input impedance set to 2 M/spl Omega/ at 1 kHz. The telemeter was loaded on a cockroach and the neural activity during a free-walk is measured through this telemetry system.","PeriodicalId":141999,"journal":{"name":"1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451)","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130691861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Continuous and pulsed microwaterjet in ophthalmology 连续脉冲微水射流在眼科中的应用

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893772

N. Smith-Guerin, M. Bétemps, A. Jutard

{"title":"Continuous and pulsed microwaterjet in ophthalmology","authors":"N. Smith-Guerin, M. Bétemps, A. Jutard","doi":"10.1109/MMB.2000.893772","DOIUrl":"https://doi.org/10.1109/MMB.2000.893772","url":null,"abstract":"At the present time, visual recovery after a penetrating keratoplasty is relatively poor. This is caused by the techniques and tools used to perform this operation. In order to improve these results the authors propose a new cutting tool for the cornea. This paper explains the surgery, the reasons of its limitations and some techniques proposed to improve the results as well. Then the device used to carry out the authors' trials and the method followed to perform the cuts with the microwaterjet are presented. Then results obtained in different conditions with continuous and pulsed microjets are discussed and compared to trephine and laser methods thanks to a histological study. The authors determined 20 bars pressure and 0.30 mm diameter is the best compromise to be used with the continuous microjet and 20 bars pressure and 0.36 mm diameter with pulsation frequency of 80 Hz the best one for pulsed microjet. Also, the authors showed microwaterjet doesn't create damage to the tissue (contrary to laser treatment), allows one to obtain quasi-straight edges of cut (contrary to using trephine) but generates a hydration put in order by the tissue.","PeriodicalId":141999,"journal":{"name":"1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451)","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130962656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Tracking a protozoon using high-speed visual feedback 利用高速视觉反馈追踪原生动物

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893761

H. Oku, I. Ishii, M. Ishikawa

引用次数: 24

Learning from nature-polymer surfaces with a nano structure that utilise the Lotus-Effect and clean themselves 学习自然聚合物表面的纳米结构，利用荷花效应和自我清洁

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893798

M. Oles, E. Nun, G. Dambacher, B. Schleich

引用次数: 3

The thermal effects on deformation processes of the porous materials 热对多孔材料变形过程的影响

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893822

B. Punantapong

引用次数: 0

Flow of /spl lambda/-DNA in microfluidic devices /spl λ /-DNA在微流控装置中的流动

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893818

P. Shrewsbury, S. Muller, D. Liepmann

引用次数: 1

Stretching and cutting of a single DNA molecule 拉伸和切割单个DNA分子

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893740

S. Katsura, N. Harada, T. Sato, K. Imayou, Y. Maeda, S. Matsuura, K. Hirano, K. Takashima, Y. Matsuzawa, A. Mizuno

{"title":"Stretching and cutting of a single DNA molecule","authors":"S. Katsura, N. Harada, T. Sato, K. Imayou, Y. Maeda, S. Matsuura, K. Hirano, K. Takashima, Y. Matsuzawa, A. Mizuno","doi":"10.1109/MMB.2000.893740","DOIUrl":"https://doi.org/10.1109/MMB.2000.893740","url":null,"abstract":"A conventional method of DNA sequencing can determine up to 1000 base pairs at one time. A long piece of DNA should be cut up into many short DNA fragments that are suitable for DNA sequencing. These DNA fragments, however, lose their order information. If the fragments are prepared from the terminus of the long chromosomal DNA, the reorganization process can be omitted. To achieve this, a single DNA molecule should be fixed with a stretched form, and sequentially cut from the terminus to prepare fragments that keep order information. In this report, a novel stretching and cutting method for single DNA molecules are presented. The method of stretching is based on manipulation and reversible change of globular DNA molecules. The globular DNA can be easily manipulated by electrostatic force, because this transition suppresses breakdown of long DNA molecules due to shear stress accompanied with flow. A single globular DNA molecule was anchored at the tip of needle electrode of tungsten. When the globular DNA was reverted to coiled state by reducing concentrations of condensing reagents, the coiled DNA was sequentially spun from the globular DNA like a spindle. By manipulating the tip of the needle electrode, chromosomal DNA was spun and fixed on a glass surface successfully in arbitrary. To prepare s fragment from the DNA molecule stretched as previously, a method to cut DNA molecules should be developed. Since most restriction enzymes require magnesium ions for their activation, the restriction enzyme activity can be localized by controlling the local concentration of magnesium ions. The local concentration of magnesium ions can be controlled electrochemically by applying a DC voltage to a needle electrode of magnesium metal. The restriction enzyme was successfully activated only when magnesium ions were electrochemically supplied.","PeriodicalId":141999,"journal":{"name":"1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2000-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133840975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Micro-blood flow measurement using thermal conductivity micro-needles: a new CMOS compatible manufacturing process onto porous silicon 利用导热微针进行微血流测量:一种新的CMOS兼容制造工艺

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893767

S. Perichon, P. Roussel, V. Lysenko, B. Remaki, D. Barbier, J. Tritto, G. Delhomme, A. Dittmar

引用次数: 5

Micro instrumentation for non-invasive measurement of mechanical properties of tissues 用于非侵入性测量组织机械性能的微型仪器

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893771

G. Scalari, A. Eisinberg, A. Menciassi, M. Carrozza, P. Dario

引用次数: 3

In-situ adhesion studies of a single living bovine endothelial cell using MEMS sensor 利用MEMS传感器原位粘附单个活牛内皮细胞的研究

1st Annual International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology. Proceedings (Cat. No.00EX451) Pub Date : 2000-10-12 DOI: 10.1109/MMB.2000.893745

C. Sager, P. LeDuc, T. Saif

引用次数: 5