International Journal of Nephrology and Renovascular Disease最新文献

筛选
英文 中文
Hyperkalemia and the Use of New Potassium Binders a Single Center Experience from Vestfold Norway (The PotBind Study). 高钾血症和新型钾结合剂的使用——来自挪威Vestfold的单中心经验(PotBind研究)。
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S401623
Thea Bjune, Thea Bjerkestrand Bøe, Stig Arne Kjellevold, Kristian Heldal, Sadollah Abedini
{"title":"Hyperkalemia and the Use of New Potassium Binders a Single Center Experience from Vestfold Norway (The PotBind Study).","authors":"Thea Bjune,&nbsp;Thea Bjerkestrand Bøe,&nbsp;Stig Arne Kjellevold,&nbsp;Kristian Heldal,&nbsp;Sadollah Abedini","doi":"10.2147/IJNRD.S401623","DOIUrl":"https://doi.org/10.2147/IJNRD.S401623","url":null,"abstract":"<p><strong>Purpose: </strong>Hyperkalemia is a common metabolic complication of chronic kidney disease (CKD) and is associated with several serious adverse events. We aimed to treat/prevent hyperkalemia using the new of potassium-binders, allowing maintained renin-angiotensin-aldosterone system inhibitors (RAASi) treatment in proteinuric CKD and/or congestive heart failure (CHF) patients.</p><p><strong>Patients and methods: </strong>We conducted a retrospective cohort study in long-term users of potassium binders for chronic hyperkalemia. Patients aged 18 years and older, treated with potassium-binders and who met the reimbursement criteria and indication for RAASi treatment were included.</p><p><strong>Results: </strong>Fifty-seven percent of the patients were males and mean age was 65 years. During the study period, no patients were admitted to hospital due to hyperkalemia after initiation of potassium binders. Potassium maximum values were significantly lower after treatment. Few patients reported major side effects, and discontinuation was mostly due to normokalemia. We found no significant changes in bicarbonate, serum creatinine or GFR stage after starting potassium binder treatment. All patients on RAASi treatment before initiating potassium-binders were retained on RAASi treatment.</p><p><strong>Conclusion: </strong>New potassium binders in clinical practice are an easy and safe treatment with few side effects and good tolerance, that significantly lowers the risk of hyperkalemia. Furthermore, and most importantly, patients can be maintained on RAASi treatment.</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e8/4c/ijnrd-16-73.PMC10027611.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9363532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Time to Diabetic Nephropathy and its Predictors Among Diabetic Patients Treated in Wolaita and Dawuro Zone Hospitals, Ethiopia: A Retrospective Cohort Study. 埃塞俄比亚Wolaita和Dawuro地区医院治疗的糖尿病患者发生糖尿病肾病的时间及其预测因素:一项回顾性队列研究
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S396574
Tiwabwork Tekalign, Mistire Teshome Guta, Nefsu Awoke, Tesfaye Yitna Chichiabellu, Mengistu Meskele, Gubay Anteneh, Tilahun Saol Tura, Shimelash Bitew Workie
{"title":"Time to Diabetic Nephropathy and its Predictors Among Diabetic Patients Treated in Wolaita and Dawuro Zone Hospitals, Ethiopia: A Retrospective Cohort Study.","authors":"Tiwabwork Tekalign,&nbsp;Mistire Teshome Guta,&nbsp;Nefsu Awoke,&nbsp;Tesfaye Yitna Chichiabellu,&nbsp;Mengistu Meskele,&nbsp;Gubay Anteneh,&nbsp;Tilahun Saol Tura,&nbsp;Shimelash Bitew Workie","doi":"10.2147/IJNRD.S396574","DOIUrl":"https://doi.org/10.2147/IJNRD.S396574","url":null,"abstract":"<p><strong>Background: </strong>Diabetic kidney disease (DKD) develops in nearly half of patients with type 2 diabetes mellitus (DM) and one-third of those with type 1 DM during their lifetime. The incidence of DKD as a cause of end stage renal disease is increasing each year. So this study aimed to assess the time to develop diabetic nephropathy and predictors among diabetic patients treated in Wolaita zone hospitals.</p><p><strong>Methodology: </strong>A ten-year retrospective cohort study had conducted among 614 diabetic patients using systematic random sampling in Wolaita and Dawuro zone hospitals. Bivariable and multivariable Cox proportional hazards regression had used to identify the possible associations between variables. Those variables with a p-value of less than 0.25 in bivariable analysis exported to multivariable Cox regression analysis. Finally, variables with p-value less than 0.05 at multivariable Cox regression were considered significantly significant. The Cox-proportional hazard model assumption had checked using the Schoenfeld residual test.</p><p><strong>Results: </strong>Of the total participants, 93 (15.3%; 95% CI = 12.45-18.14) patients had developed nephropathy in 820,048 people year observation. A mean time to diabetic nephropathy in this study was 189.63 (95% CI, 185.01, 194.25) months. Being illiterate (AHR: 2.21, 95% CI: 1.34-3.66), being hypertensive (AHR: 5.76, 95% CI: 3.39-9.59), and being urban dwellers (AHR: 2.25, 95% CI: 1.34-3.77) increases the hazard of nephropathy.</p><p><strong>Conclusion: </strong>According to this follow-up study, the overall incidence rate is substantially high over ten year follow-up period. The mean time to develop diabetic nephropathy was sixteen years. Educational status, place of residence, and being hypertensive were the predictors. So stakeholders should work on complication reduction measures and awareness creation of the impact of comorbidities.</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f0/e7/ijnrd-16-163.PMC10275322.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9716278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Survival Rates in Elderly Patients on Continuous Ambulatory Peritoneal Dialysis. 老年患者持续非卧床腹膜透析的生存率。
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S397555
Bach Nguyen, Quynh Thi Huong Bui, Phuong Que Tran
{"title":"Survival Rates in Elderly Patients on Continuous Ambulatory Peritoneal Dialysis.","authors":"Bach Nguyen,&nbsp;Quynh Thi Huong Bui,&nbsp;Phuong Que Tran","doi":"10.2147/IJNRD.S397555","DOIUrl":"https://doi.org/10.2147/IJNRD.S397555","url":null,"abstract":"<p><strong>Purpose: </strong>The present study aimed at evaluating the survival rate, its associated factors, and the causes of death in elderly patients undergoing continuous ambulatory peritoneal dialysis (CAPD) in Vietnam.</p><p><strong>Patients and methods: </strong>This is a retrospective, observational study conducted among patients aged ≥65 years who underwent CAPD at Thong Nhat Hospital, Ho Chi Minh City, Vietnam, from April 2012 to December 2020. The Kaplan-Meier method was used to calculate the cumulative survival rate, and the Log rank test was used to analyze the factors associated with the survival rate of patients.</p><p><strong>Results: </strong>This study enrolled a total of 68 patients with a mean age of 71.93 ± 7.44 years at the initiation of CAPD. The most common complication among kidney failure patients was diabetic nephropathy (39.71%). The rate of concomitant cardiovascular diseases was 58.82%. The average survival rate was 45.59 ± 4.01 months. Peritonitis was the most common factor causing death (31.25%), followed by cardiovascular diseases (28.12%) and malnutrition (25%). The factors that impacted the survival rate included concomitant cardiovascular diseases, low serum albumin (<35 g/dL), and an indication of CAPD due to exhausted vascular access for hemodialysis at baseline. The main factor associated with a shorter survival time was concomitant cardiovascular diseases.</p><p><strong>Conclusion: </strong>It is necessary to improve the survival time beyond 5 years for elderly patients undergoing CAPD, especially for those with concomitant cardiovascular diseases. Besides the prevention of peritonitis, adequate measures to protect from cardiovascular diseases and malnutrition will reduce the mortality rate in patients on CAPD.</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c9/29/ijnrd-16-131.PMC10122850.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9438018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-Life Anemia Management Among Patients with Non-Dialysis-Dependent Chronic Kidney Disease in Three European Countries. 三个欧洲国家非透析依赖型慢性肾病患者的现实生活贫血管理
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S401598
Danilo Fliser, Maria Mata Lorenzo, Katherine Houghton, Claire Ainsworth, Martin Blogg, Elena González de Antona Sánchez, Jose Portoles
{"title":"Real-Life Anemia Management Among Patients with Non-Dialysis-Dependent Chronic Kidney Disease in Three European Countries.","authors":"Danilo Fliser,&nbsp;Maria Mata Lorenzo,&nbsp;Katherine Houghton,&nbsp;Claire Ainsworth,&nbsp;Martin Blogg,&nbsp;Elena González de Antona Sánchez,&nbsp;Jose Portoles","doi":"10.2147/IJNRD.S401598","DOIUrl":"https://doi.org/10.2147/IJNRD.S401598","url":null,"abstract":"<p><strong>Background: </strong>Anemia is prevalent among patients with chronic kidney disease (CKD), yet current evidence indicates that treatment may not adhere to Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. We aimed to document the management of patients with non-dialysis-dependent (NDD)-CKD receiving erythropoiesis-stimulating agent (ESA) therapy in Europe.</p><p><strong>Methods: </strong>This retrospective, observational study extracted information from medical records in Germany, Spain, and the UK. Eligible patients were adults with NDD-CKD stages 3b-5 who initiated ESA therapy for anemia between January and December 2015. Anemia was defined as hemoglobin (Hb) <13.0 g/dL (males) or <12.0 g/dL (females). Data regarding ESA treatment, treatment response, concomitant iron therapy and blood transfusions were extracted up to 24 months post-ESA initiation, and data on CKD progression until abstraction date.</p><p><strong>Results: </strong>Eight hundred and forty-eight medical records were abstracted. Approximately 40% received no iron therapy prior to ESA initiation. At ESA initiation, mean ± standard deviation Hb level was 9.8 ± 1.0 g/dL. Most patients received darbepoetin alfa, and switching between ESAs was rare (8.5% of patients). Concomitant intravenous and oral iron therapy was prescribed for 36% and 42% of patients, respectively, during initial ESA therapy. Mean Hb levels reached the target level (10-12 g/dL) within 3-6 months of ESA initiation. Hb, transferrin saturation, and ferritin levels were infrequently monitored from 3 months post-ESA initiation. Rates of blood transfusion, dialysis, and diagnosis of end-stage renal disease were 16.4%, 19.3%, and 24.6%, respectively. Rates of kidney transplant and death were 4.8% and 8.8%, respectively.</p><p><strong>Conclusion: </strong>Among ESA-treated patients, ESA initiation was in accordance with KDIGO guidelines, but subsequent monitoring of Hb and iron deficiency were suboptimal.</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d6/54/ijnrd-16-115.PMC10108867.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9441189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management. 慢性肾脏疾病的遗传易感性:联系、风险和管理。
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S363041
Hanny Sawaf, Tariku T Gudura, Sylvester Dorobisz, Dianne Sandy, Xiangling Wang, Shane A Bobart
{"title":"Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management.","authors":"Hanny Sawaf,&nbsp;Tariku T Gudura,&nbsp;Sylvester Dorobisz,&nbsp;Dianne Sandy,&nbsp;Xiangling Wang,&nbsp;Shane A Bobart","doi":"10.2147/IJNRD.S363041","DOIUrl":"https://doi.org/10.2147/IJNRD.S363041","url":null,"abstract":"<p><p>Chronic kidney disease (CKD) is associated with significant morbidity and mortality worldwide. In recent years, our understanding of genetic causes of CKD has expanded significantly with several renal conditions having been identified. This review discusses the current landscape of genetic kidney disease and their potential treatment options. This review will focus on cystic kidney disease, glomerular disease with genetic associations, congenital anomalies of kidneys and urinary tract (CAKUT), autosomal dominant-tubulointerstitial kidney disease (ADTKD), inherited nephrolithiasis and nephrocalcinosis.</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f6/0b/ijnrd-16-1.PMC9831004.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10528310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survival Analysis and Its Predictors Among Hemodialysis Patients at Saint Paul Hospital Millennium Medical College and Myungsung Christian Medical Center in Addis Ababa, Ethiopia, 2021. 2021年埃塞俄比亚亚的斯亚贝巴圣保罗医院千年医学院和明成基督教医疗中心血液透析患者的生存分析及其预测因素
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S401022
Eyob Assefa Betiru, Ephrem Mamo, Dube Jara Boneya, Abebawork Adem, Dessie Abebaw
{"title":"Survival Analysis and Its Predictors Among Hemodialysis Patients at Saint Paul Hospital Millennium Medical College and Myungsung Christian Medical Center in Addis Ababa, Ethiopia, 2021.","authors":"Eyob Assefa Betiru,&nbsp;Ephrem Mamo,&nbsp;Dube Jara Boneya,&nbsp;Abebawork Adem,&nbsp;Dessie Abebaw","doi":"10.2147/IJNRD.S401022","DOIUrl":"https://doi.org/10.2147/IJNRD.S401022","url":null,"abstract":"<p><strong>Background: </strong>Diabetes mellitus and hypertension are the most prominent conditions causing chronic kidney disease and eventually end-stage renal disease. Renal replacement therapy, particularly hemodialysis (HD), is the mainstay of treatment. The aim of this study is to assess the overall survival status of HD patients and potential survival predictors at Saint Paul hospital millennium medical college (SPHMMC) and Myungsung Christian Medical Center (MCM) in Addis Ababa, Ethiopia.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted on HD patients at SPHMMC and MCM general hospital from January 1, 2013 to December 30, 2020. Kaplan Meier, Log-rank, and Cox proportional regression models were used for the analysis. Estimated risks were reported as hazard ratios with 95% confidence intervals and <i>P</i><0.05 was considered as having a significant association.</p><p><strong>Results: </strong>A total of 128 patients were included in the study. Median survival time was 65 months. The predominant co-morbid condition was found to be diabetes mellitus with hypertension (42%). The total risk time for these patients was 143,617 person years. The overall incidence rate of death was 2.9 per 10,000 person years (95% CI=2.2-4). Patients who developed blood stream infection were 2.98-times more likely to die than those without infection. Those using an arteriovenous fistula were 66% less likely to die than those using a central venous catheter. Additionally, patients treated in a government-owned facility were 79% less likely to die.</p><p><strong>Conclusion: </strong>The study identified that the median survival time of 65 months was comparable with developed nations. Significant predictors of death were found to be blood stream infection and type of vascular access. Government-owned treatment facilities showed better patient survival.</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/54/b5/ijnrd-16-59.PMC9983441.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9100260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging Role of Sodium-Glucose Co-Transporter 2 Inhibitors for the Treatment of Chronic Kidney Disease. 钠-葡萄糖共转运蛋白2抑制剂在慢性肾病治疗中的新作用
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S387262
Rey Isidto, Romina Danguilan, Oscar Naidas, Russell Vilanueva, Mel-Hatra Arakama, Layla Marie Paraiso
{"title":"Emerging Role of Sodium-Glucose Co-Transporter 2 Inhibitors for the Treatment of Chronic Kidney Disease.","authors":"Rey Isidto,&nbsp;Romina Danguilan,&nbsp;Oscar Naidas,&nbsp;Russell Vilanueva,&nbsp;Mel-Hatra Arakama,&nbsp;Layla Marie Paraiso","doi":"10.2147/IJNRD.S387262","DOIUrl":"https://doi.org/10.2147/IJNRD.S387262","url":null,"abstract":"<p><p>Chronic kidney disease is one of the leading causes of morbidity and mortality in the Philippines. It is associated with a growing health burden as many patients progress to end-stage renal disease. Until recently, therapeutic options for the management of chronic kidney disease were limited. Sodium-glucose co-transporter 2 inhibitors offer an alternative therapeutic approach for patients with chronic kidney disease. Several trials have shown renal benefits with sodium-glucose co-transporter 2 inhibitors in patients with cardiovascular disease with and without type 2 diabetes and across a range of estimated glomerular filtration rate levels. In the Philippines, the sodium-glucose co-transporter 2 inhibitors dapagliflozin and canagliflozin are approved for the prevention of new and worsening nephropathy in type 2 diabetes. With emerging treatment options, an urgent need exists for guidance on the management of chronic kidney disease within the Philippines. In this review, we focus on the putative renal-protective mechanisms of sodium-glucose co-transporter 2 inhibitors, including effects on tubuloglomerular feedback, albuminuria, endothelial function, erythropoiesis, uric acid levels, renal oxygen demand, and hypoxia. Furthermore, we discuss the findings of recent large clinical trials using sodium-glucose co-transporter 2 inhibitors in patients with chronic kidney disease and diabetic kidney disease, summarize safety aspects, and outline the practical management of patients with chronic kidney disease in the Philippines.</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/df/0e/ijnrd-16-43.PMC9960786.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9353125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cranial versus Caudal Direction Technique of Native Percutaneous Kidney Biopsy: A Randomized Controlled Trial. 经皮肾活检的颅侧与尾侧技术:一项随机对照试验。
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S400639
Solos Jaturapisanukul, Chutima Chavanisakun, Nontawat Benjakul, Tanun Ngamvichchukorn, Punnawit Laungchuaychok, Sathit Kurathong, Wanjak Pongsittisak
{"title":"Cranial versus Caudal Direction Technique of Native Percutaneous Kidney Biopsy: A Randomized Controlled Trial.","authors":"Solos Jaturapisanukul,&nbsp;Chutima Chavanisakun,&nbsp;Nontawat Benjakul,&nbsp;Tanun Ngamvichchukorn,&nbsp;Punnawit Laungchuaychok,&nbsp;Sathit Kurathong,&nbsp;Wanjak Pongsittisak","doi":"10.2147/IJNRD.S400639","DOIUrl":"https://doi.org/10.2147/IJNRD.S400639","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous kidney biopsy (PKB) is the gold standard for diagnosing various kidney diseases, but it can result in potential complications. This study aimed to compare kidney tissue adequacy and safety between the two biopsy techniques, including cranial direction (CN) and caudal direction (CD), of needle biopsy under real-time ultrasonogram guidance.</p><p><strong>Methods: </strong>This single-center, prospective, single-blinded, randomized trial included patients undergoing native PKB from July 5, 2017, to June 30, 2019. Patients were randomized to the CN and CD groups. Adequacy and complications between the two groups were analyzed. All PKBs were performed under real-time ultrasonogram guidance with a 16-gauge kidney biopsy needle.</p><p><strong>Results: </strong>A total of 107 participants were enrolled (53 in the CD group and 54 in the CN group). The CD group has more glomeruli than the CN group but with no statistical significance (16 versus 11, <i>p</i> = 0.0865). The CD group obtained more adequate kidney tissue samples than the CN group (69.8% versus 59.3%, <i>p</i> = 0.348). The number of inadequate glomeruli tissue sampling is similar in both groups (14 versus 15, respectively). Furthermore, the CN group had more adverse events, including Hb decline ≥10% after kidney biopsy, perinephric hematoma size ≥1 cm, hematuria, and the need for blood transfusion, than the CD group.</p><p><strong>Conclusion: </strong>The CD technique of the percutaneous kidney biopsy in the native kidney has fewer complications and was possibly more effective than the CN technique.</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c4/b5/ijnrd-16-93.PMC10066630.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9302105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic Kidney Disease Management in the Middle East and Africa: Concerns, Challenges, and Novel Approaches. 中东和非洲的慢性肾脏疾病管理:关注、挑战和新方法。
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S363133
Saeed Al-Ghamdi, Ali Abu-Alfa, Turki Alotaibi, Ali AlSaaidi, Abdulkareem AlSuwaida, Mustafa Arici, Tevfik Ecder, Ahmed F El Koraie, Mohamed Ghnaimat, Mohamed H Hafez, Mohamed Hassan, Tarik Sqalli
{"title":"Chronic Kidney Disease Management in the Middle East and Africa: Concerns, Challenges, and Novel Approaches.","authors":"Saeed Al-Ghamdi,&nbsp;Ali Abu-Alfa,&nbsp;Turki Alotaibi,&nbsp;Ali AlSaaidi,&nbsp;Abdulkareem AlSuwaida,&nbsp;Mustafa Arici,&nbsp;Tevfik Ecder,&nbsp;Ahmed F El Koraie,&nbsp;Mohamed Ghnaimat,&nbsp;Mohamed H Hafez,&nbsp;Mohamed Hassan,&nbsp;Tarik Sqalli","doi":"10.2147/IJNRD.S363133","DOIUrl":"https://doi.org/10.2147/IJNRD.S363133","url":null,"abstract":"<p><p>The burden of chronic kidney disease (CKD) and other comorbidities, such as hypertension and diabetes, which increase the risk of developing CKD, is on the rise in the Middle East and Africa. The Middle East and Africa CKD (MEA-CKD) steering committee, comprising eminent healthcare specialists from the Middle East and Africa, was formed to identify and propose steps to address the gaps in the management of CKD in these regions. The current article lists the MEA-CKD steering committee meeting outcomes and evaluates the available evidence supporting the role of novel therapeutic options for patients with CKD. The need of the hour is to address the gaps in awareness and screening, early diagnosis, along with referral and management of patients at risk. Measures to bring about appropriate changes in healthcare policies to ensure access to all benefit-proven protective therapies, including novel ones, at community levels are also vital for reducing the overall burden of CKD on the healthcare system as well as governing bodies, especially in developing countries of the Middle East and Africa.</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c4/16/ijnrd-16-103.PMC10084934.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9673820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Erratum: Hyperkalemia and the Use of New Potassium Binders a Single Center Experience from Vestfold Norway (The PotBind Study) [Corrigendum]. 勘误:高钾血症和新钾结合剂的使用:来自挪威Vestfold的单中心经验(PotBind研究)[勘误]。
IF 2
International Journal of Nephrology and Renovascular Disease Pub Date : 2023-01-01 DOI: 10.2147/IJNRD.S416069
{"title":"Erratum: Hyperkalemia and the Use of New Potassium Binders a Single Center Experience from Vestfold Norway (The PotBind Study) [Corrigendum].","authors":"","doi":"10.2147/IJNRD.S416069","DOIUrl":"https://doi.org/10.2147/IJNRD.S416069","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.2147/IJNRD.S401623.].</p>","PeriodicalId":14181,"journal":{"name":"International Journal of Nephrology and Renovascular Disease","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/28/26/ijnrd-16-113.PMC10103777.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9303391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信