Hila Shalev-Ram, Yael Rosental, Gal Cohen, Hanoch Schriber, Michal Kovo, Tal Biron-Shental, Gil Shechter-Maor
{"title":"Does symphysiolysis during pregnancy affect obstetric outcomes?","authors":"Hila Shalev-Ram, Yael Rosental, Gal Cohen, Hanoch Schriber, Michal Kovo, Tal Biron-Shental, Gil Shechter-Maor","doi":"10.1002/ijgo.70178","DOIUrl":"https://doi.org/10.1002/ijgo.70178","url":null,"abstract":"<p><strong>Objective: </strong>Symphysiolysis Is Often Experienced by Pregnant Women and Is Known to Cause Considerable Pain and Occasional Anxiety. However, Information on Obstetrical and Neonatal Outcomes Is Limited. Our Objective Was to Compare Obstetrical and Neonatal Outcomes, and Labor Characteristics, between Women with or without Symphysiolysis.</p><p><strong>Methods: </strong>This retrospective cohort study included all women with singleton pregnancies without previous cesarean delivery who attempted vaginal delivery at ≥37 weeks in a tertiary hospital from 2013 to 2021. The cohort was divided into women diagnosed with symphysiolysis during pregnancy and a control group of women without the diagnosis. Maternal and delivery characteristics, as well as obstetric and neonatal adverse outcomes were compared between the groups. Nulliparous and multiparous women were analyzed separately. Adjusted odds ratios with 95% confidence intervals were calculated, controlling for confounding variables.</p><p><strong>Results: </strong>A total of 15 557 nulliparous and 27 477 multiparous women were included. Among them, 233 (1.5%) nulliparous and 515 (1.9%) multiparous women had a diagnosis of symphysiolysis. As compared with controls, women with symphysiolysis tended to be younger (27.5 ± 4.4 vs. 28.5 ± 5.0 years, P = 0.002 for nulliparous, 31.1 ± 4.9 vs. 32.2 ± 4.8 years, P < 0.001 for multiparous), have higher body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) prior to pregnancy (25.0 ± 5.2 vs. 23.5 ± 5.0, P < 0.001 and 25.3 ± 5.5 vs. 25.3 ± 5.5, P < 0.001, respectively), and a higher prevalence of smoking during pregnancy (7.3% vs. 4.4%, P = 0.036, and 9.3% vs. 4.7%, P < 0.001, respectively). There were no between-group differences in obstetric outcomes, including second stage of labor duration, rate of vacuum extraction, cesarean delivery, perineal laceration, or adverse neonatal outcome. Moreover, there were no significant differences observed between the groups in terms of rates of Apgar scores <7 at 5 min, arterial pH <7.1, or admissions to the neonatal intensive care unit.</p><p><strong>Conclusion: </strong>The risk of obstetrical or neonatal complications during labor for individuals with symphysiolysis are not increased.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143969714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paul Renon, Elodie Drumez, Maeva Sanchez, Julien Labreuche, Charles Garabedian
{"title":"Can shoulder dystocia be predicted before operative vaginal delivery using a score that includes ultrasonographic head-perineum distance measurement?","authors":"Paul Renon, Elodie Drumez, Maeva Sanchez, Julien Labreuche, Charles Garabedian","doi":"10.1002/ijgo.70184","DOIUrl":"https://doi.org/10.1002/ijgo.70184","url":null,"abstract":"<p><strong>Objective: </strong>The main study objective was to develop a novel shoulder dystocia (SD) prediction score using ultrasound-based head-perineum distance measured before an operative vaginal delivery (OVD).</p><p><strong>Methods: </strong>This retrospective unicentric study (Lille, France) included all cases of OVD of singleton pregnancies from March 2019 to October 2020, with cephalic presentation and > 37 weeks of gestation, for which intrapartum sonography was performed. A multiclass-penalized logistic regression model was used to develop the SD prognostic score, with missing values imputed by multiple imputations.</p><p><strong>Results: </strong>Among the 1708 patients with OVD, 773 who underwent ultrasound for head-perineum distance were included. SD occurred in 99 cases (12.8%). The SD's predicting factors (and their weights) included the following: maternal age younger than 28 years (3 points); multiparous (4 points); induced labor (4 points); gestational diabetes (3 points); and head-perineum distance without pressure (≤20 mm [-2 points], using 21-30 mm as reference, 31-40 mm [2 points], 41-50 mm [4 points], 51-60 mm [6 points], and >60 mm [8 points]). Three patient risk subgroups were categorized as score range (occurrence percentage) as low risk: < 3 (< 10%), high risk: 3-8 (10%-20%), and very high risk: > 8 (> 20%).</p><p><strong>Conclusion: </strong>The developed scoring system may help predict SD occurrence during OVD using five delivery room parameters. Replication with other populations and prospective cohorts will be needed for validation.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beatriz Teixeira, Mafalda Castro Neves, Francisca Fonseca, José Pinheiro Torres, José Teixeira, Antónia Costa
{"title":"Intravenous leiomyomatosis: A case report and narrative literature review.","authors":"Beatriz Teixeira, Mafalda Castro Neves, Francisca Fonseca, José Pinheiro Torres, José Teixeira, Antónia Costa","doi":"10.1002/ijgo.70195","DOIUrl":"https://doi.org/10.1002/ijgo.70195","url":null,"abstract":"<p><p>In the present study, we report a case of intravenous leiomyomatosis with intracardiac extension. A subsequent extensive literature review was initiated in order to characterize this entity in terms of clinical manifestations, diagnosis and treatment strategies. We performed a literature search in PubMed, Webscience and Scopus using the MeSH term \"intravenous leiomyomatosis\" and included case reports, case series and retrospective studies published in the last 10 years. A total of 74 articles, with a total of 672 cases of intravenous leiomyomatosis were included. The average age at diagnosis was 45.5 years and 92% of the cases were reported in Asian countries. A total of 21% of the patients were asymptomatic. The most frequent symptoms included perception of pelvic mass, dyspnea, abnormal uterine bleeding and palpitations. In 55% of cases there was a preoperative suspicion of the diagnosis. In 61%, the lesion was confined to the pelvic cavity and in 35% there was extension beyond the renal veins (including intracardiac extension). When there was a preoperative diagnosis, the surgical team usually included elements from gynecology, vascular surgery and/or cardiac surgery. The treatment consisted of one-stage surgery in 86% of cases, with complete resection in 90%. The recurrence rate was 12%. Intravenous leiomyomatosis can have a nonspecific presentation which, combined with its rarity, requires a high degree of suspicion. The challenges in its treatment and follow-up arise from its surgical complexity and the absence of guidelines. The objective of this review was to compile the most recent cases reported to better characterize this rare entity thereby achieving optimal management.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yutong Chen, Huizhi Wang, Wentong Zhao, Ying Wu, Min Zhu, Xueli Zhang, Yunshuang Liu
{"title":"Multicystic peritoneal mesothelioma in the myometrium during pregnancy: A case report and literature review.","authors":"Yutong Chen, Huizhi Wang, Wentong Zhao, Ying Wu, Min Zhu, Xueli Zhang, Yunshuang Liu","doi":"10.1002/ijgo.70187","DOIUrl":"https://doi.org/10.1002/ijgo.70187","url":null,"abstract":"<p><p>Multicystic peritoneal mesothelioma (MCPM) is a rare tumor originating from mesothelial cells, primarily affecting women of reproductive age and typically found in the pelvic peritoneum. Its occurrence in the myometrium is extremely rare. Currently, there have been no reported cases of MCPM in the myometrium during pregnancy, and existing clinical guidelines do not provide specific management recommendations for this condition. This article aimed to explore the diagnosis, management, and treatment for MCPM in the myometrium during pregnancy, thereby providing a valuable reference for clinicians dealing with similar cases.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aureli Torné Blade, María Del Mar Ramírez Mena, Jesús de la Fuente Valero, Raquel Oliva Sánchez, José Quílez Conde, Manuela Sala Ferichola, Jesús Osuna Pérez, Antonio Rivera, Bruno Herrera Bruch, Gonzalo Fernández, Noelia López, María Villarejo, Marta Del Pino Saladrigues
{"title":"HPV vaccination coverage rate in women undergoing conization for cervical intraepithelial neoplasia in Spain: The COVAR study.","authors":"Aureli Torné Blade, María Del Mar Ramírez Mena, Jesús de la Fuente Valero, Raquel Oliva Sánchez, José Quílez Conde, Manuela Sala Ferichola, Jesús Osuna Pérez, Antonio Rivera, Bruno Herrera Bruch, Gonzalo Fernández, Noelia López, María Villarejo, Marta Del Pino Saladrigues","doi":"10.1002/ijgo.70170","DOIUrl":"https://doi.org/10.1002/ijgo.70170","url":null,"abstract":"<p><strong>Objective: </strong>Females subjected to cervical excisional therapy (conization) due to high-grade squamous intraepithelial lesions/cervical intraepithelial neoplasia HSIL/CIN have a higher risk of developing cervical lesions compared to the general population. Research suggests that HPV vaccination may reduce post-treatment HSIL/CIN risk. Since 2014, HPV vaccination is recommended and funded in Spain at regional level for women who had undergone treatment for cervical precancerous lesions (HSIL/CIN2-3 or any other potentially tumoral cytohistological alteration). In 2018, the Ministry of Health standardized the recommendations but the vaccination coverage rate (VCR) for this population has not been published. The COVAR Study aimed to estimate the annual HPV VCR among women undergoing conization for SIL/CIN in Spain and assess sociodemographic and COVID-19 pandemic influence. To estimate the annual HPV vaccination coverage rate (VCR) among women undergoing conization for squamous intraepithelial lesions/cervical intraepithelial neoplasia (SIL/CIN) in Spain and assess the influence of sociodemographics and the COVID-19 pandemic.</p><p><strong>Methods: </strong>This was a multicentric, cross-sectional retrospective study conducted in six Spanish public hospitals from January 1, 2019, to December 31, 2021.</p><p><strong>Results: </strong>Annual HPV VCR was 87.3% (1135/1300), increasing to 89.8% (983/1095) in women with a conization for high-grade SIL (HSIL)/CIN. Among vaccinated women, 30.2% (343/1135) were vaccinated after SIL/CIN diagnosis but before conization and 58.3% (662/1135) were vaccinated after conization; the remaining 11.5% (130/1135) received at least one dose before SIL/CIN diagnosis. Of the conizations, 32.4% (517/1594) were performed during the pre-pandemic period, decreasing to 19.6% (312/1594) during the first COVID-19 restriction period; the annual HPV VCR also decreased (30% [259/865] to 20.7% [179/865], P < 0.001), for women vaccinated after conization.</p><p><strong>Conclusion: </strong>The annual HPV VCR in our population was 87.3%, reflecting effective vaccination strategies. The COVID-19 pandemic substantially impacted the annual percentage of conizations and HPV vaccination.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144012165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prediction of cardiac events in pregnant women with cardiac diseases using modified WHO, CARPREG II, and ZAHARA risk assessments in southern Thailand.","authors":"Panisa Poungsuntorn, Chitkasaem Suwanrath, Natthicha Chainarong, Krantarat Peeyananjarassri, Sirichai Cheewatanakornkul, Pongsanae Duangpakdee, Kanjarut Wongwaitaweewong","doi":"10.1002/ijgo.70196","DOIUrl":"https://doi.org/10.1002/ijgo.70196","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare the predictive performance of three cardiovascular risk assessment models-modified WHO (mWHO) classification, Cardiac Disease in Pregnancy II (CARPREG II), and Zwangerschap bij Aangeboren Hartafwijking (Pregnancy in Women with Congenital Heart Disease; ZAHARA)-in predicting cardiac events among pregnant women with cardiac diseases.</p><p><strong>Methods: </strong>A retrospective review of medical records was conducted for all pregnant women with cardiac diseases who delivered at Songklanagarind Hospital between January 1, 2011, and December 31, 2022. Pregnancies ending in termination or miscarriage before 24 weeks were excluded. The mWHO, CARPREG II, and ZAHARA classifications were applied to each patient, with ZAHARA used only for congenital cardiac diseases. The discriminative ability of each model was evaluated using the area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>Among 333 pregnancies with cardiac diseases (163 congenital and 170 acquired), 100 (30.0%) experienced cardiac events. The AUCs for predicting cardiac events in all cases were 0.774 (95% confidence interval [CI] 0.719-0.826) for CARPREG II and 0.744 (95% CI 0.689-0.799) for mWHO. In acquired cardiac disease, the AUC for mWHO (0.700 [95% CI 0.621-0.779]) was higher than that for CARPREG II (0.677 [95% CI 0.596-0.758]). For congenital cardiac disease, CARPREG II exhibited the best predictive performance, followed by mWHO and ZAHARA, with AUC values of 0.768 (95% CI 0.658-0.877), 0.754 (95% CI 0.653-0.854), and 0.685 (95% CI 0.563-0.806), respectively.</p><p><strong>Conclusion: </strong>CARPREG II demonstrated the highest predictive performance for cardiac events in pregnant women with all cardiac diseases, while ZAHARA exhibited the lowest predictive performance for congenital cardiac diseases.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trends in mortality related to malignant neoplasms of female genital organs in young females in the United States, 1999-2023.","authors":"Sameen Aftab, Qazi Muhammad Zarlish","doi":"10.1002/ijgo.70162","DOIUrl":"https://doi.org/10.1002/ijgo.70162","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the site-specific mortality and demographic, racial, and regional trends of mortality related to malignant neoplasms of female genital organs in young females in the USA, 1999-2023 and to highlight the importance of targeted health policies.</p><p><strong>Methods: </strong>This was an analysis of a database that was collected by the CDC prospectively between 1999 and 2023.</p><p><strong>Results: </strong>An overall decrease in age-adjusted gynecologic cancer-related mortality rates in young females through the years 1999-2023, although the age-adjusted mortality rate increased slightly from 2010 to 2023.</p><p><strong>Conclusion: </strong>There is an urgent need to devise targeted health policies to reduce the burden of malignant neoplasms of genital organs in young females, keeping in view the site and demographic, regional, and racial disparities.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In Memoriam: Charles Ngwena.","authors":"Rebecca Cook, Bernard Dickens","doi":"10.1002/ijgo.70092","DOIUrl":"https://doi.org/10.1002/ijgo.70092","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":"169 2","pages":"456-457"},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between umbilical cord arterial pH and neurodevelopment of offspring at the age of 3 years: The Japan environment and Children's study.","authors":"Hyo Kyozuka, Tsuyoshi Murata, Takahiro Omoto, Toma Fukuda, Shun Yasuda, Toshifumi Takahashi, Akiko Sato, Yuka Ogata, Mitsuaki Hosoya, Seiji Yasumura, Koichi Hashimoto, Keiya Fujimori, Hidekazu Nishigori","doi":"10.1002/ijgo.70179","DOIUrl":"https://doi.org/10.1002/ijgo.70179","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the association between umbilical cord pH at birth and neurodevelopment in 3-year-old offspring.</p><p><strong>Methods: </strong>In this prospective cohort study, we identified 71 680 term deliveries in Japanese women recruited to the Japan Environment and Children's Study (JECS) between January 2011 and March 2014. Data on singleton pregnancies involving live-term births between 2011 and 2014 were extracted from the JECS database. Participants were stratified into umbilical cord artery pH (UmA-pH) quintiles (G1: pH ≥7.30 and G5: pH <7.00) and sex. G1 acted as a reference for the multiple logistic regression model used to estimate the effect of UmA-pH on impaired neurodevelopment at 3 years of age using the Age and Stages Questionnaire, third edition. The main outcome measure was neurodevelopmental state of 3-year-old children.</p><p><strong>Results: </strong>We obtained 71 680 maternal and neonatal paired records (36 499 male and 35 181 female offspring). This study found that male offspring in the G5 group had an increased risk of communication, gross motor, and fine motor skill impairments. The adjusted odds ratios (aOR) for G5 male offspring were 2.60 (95% confidence interval [CI] 1.23-5.53), 4.22 (95% CI 2.17-8.20), and 1.94 (95% CI 1.00-3.76) for communication, gross motor, and fine motor skills impairment, respectively. The aOR for G5 female offspring was 4.15 (95% CI 1.27-13.61) for social skills impairment.</p><p><strong>Conclusion: </strong>Low UmA-pH, less than 7.00, was associated with neurodevelopmental outcomes in the offspring, and sex differences were observed, indicating the need for individual follow up of newborns with low UmA-pH.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Şeyma Kilci Erciyas, Ebru Cirban Ekrem, Şirin Çetin
{"title":"Menstruation myths scale: A scale development study.","authors":"Şeyma Kilci Erciyas, Ebru Cirban Ekrem, Şirin Çetin","doi":"10.1002/ijgo.70122","DOIUrl":"https://doi.org/10.1002/ijgo.70122","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to develop a scale of menstruation myths.</p><p><strong>Methods: </strong>The current research was conducted using a methodologic approach with a sample of 330 women who met the inclusion criteria. The scope, structural validity, and internal consistency of the scale were tested.</p><p><strong>Results: </strong>As a result of the analyses, it was determined that the scale consisted of 18 items and three factors that explain approximately 57% of the total variance. The Cronbach α value of the scale was 0.86 in the first factor, 0.82 in the second factor, 0.83 in the third factor, and 0.91 in total.</p><p><strong>Conclusion: </strong>The Menstruation Myths Scale was found to be a valid and reliable measuring tool for reproductive-aged women in Turkish society. It is recommended that the scale be tested with women of different ages, populations, and countries. Additionally, it is believed that the scale can be used to determine myths about menstruation among men.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}