International Journal of Gynecology & Obstetrics最新文献

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Attitudes toward conservative management of pelvic organ prolapse and stress urinary incontinence with vaginal pessaries: A national survey among Israeli obstetricians and gynecologists. 对盆腔器官脱垂和阴道托压力性尿失禁保守管理的态度:以色列妇产科医生的一项全国性调查。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-12 DOI: 10.1002/ijgo.70052
Nadav Cohen, Reut Rotem, Adi Y Weintraub, May Shafir, Yael Barkan, Noga Porat, Ariel Zilberlicht
{"title":"Attitudes toward conservative management of pelvic organ prolapse and stress urinary incontinence with vaginal pessaries: A national survey among Israeli obstetricians and gynecologists.","authors":"Nadav Cohen, Reut Rotem, Adi Y Weintraub, May Shafir, Yael Barkan, Noga Porat, Ariel Zilberlicht","doi":"10.1002/ijgo.70052","DOIUrl":"https://doi.org/10.1002/ijgo.70052","url":null,"abstract":"<p><strong>Objective: </strong>To explore the views of Israeli gynecologists regarding the use of vaginal pessaries for management of pelvic organ prolapse (POP) and stress urinary incontinence (SUI), which are common medical conditions that affect women and can significantly impact their quality of life.</p><p><strong>Methods: </strong>An electronic survey containing questions assessing knowledge, training, and attitudes regarding the use of vaginal pessaries for POP and SUI was distributed among Israeli gynecologists. Data were collected and recorded anonymously. Descriptive statistics were used to summarize the responses.</p><p><strong>Results: </strong>A total of 700 emails were sent, with a response rate of 53% (371 responses). The majority of respondents (76.4%, n = 283) consulted a urogynecologist before and after fitting a pessary; however, 60.4% (n = 224) felt that any gynecologist should be able to follow up on such cases. When stratified by years of experience, physicians with fewer than 10 years of experience were more likely to offer pessary treatment (31.6%, n = 117 vs. 19.1%, n = 71, P < 0.01). However, those who did not offer pessaries felt more uncertain about fitting them and were more likely to report a lack of experience (24.8%, n = 92 vs. 13.6%, n = 50, P < 0.01, and 18.0%, n = 67 vs. 6.2%, n = 23, P < 0.01, respectively).</p><p><strong>Conclusions: </strong>Our survey highlights a gap in knowledge and training among Israeli gynecologists regarding the conservative management of POP and SUI with vaginal pessaries. There is a clear desire among physicians to acquire these skills. The establishment of formal training programs is crucial to bridging this gap and improving women's health outcomes.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of Doppler studies in predicting non-reassuring fetal heart rate monitoring following induction of labor. 多普勒研究在预测引产后不可靠胎儿心率监测中的作用。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-12 DOI: 10.1002/ijgo.70048
Eldar Volpert, Daniel Tairy, Liliya Tamayev, Yossi Mizrachi, Jacob Bar, Eran Weiner, Giulia Barda
{"title":"The role of Doppler studies in predicting non-reassuring fetal heart rate monitoring following induction of labor.","authors":"Eldar Volpert, Daniel Tairy, Liliya Tamayev, Yossi Mizrachi, Jacob Bar, Eran Weiner, Giulia Barda","doi":"10.1002/ijgo.70048","DOIUrl":"https://doi.org/10.1002/ijgo.70048","url":null,"abstract":"<p><strong>Objective: </strong>We studied whether Doppler flow measurements before initiation of induction of labor (IOL) can predict non-reassuring fetal heart rate (NRFHR) monitoring in women at 38-41 weeks of gestation.</p><p><strong>Materials and methods: </strong>We performed a prospective observational study in a single tertiary medical center between November 2017 and December 2019. Women undergoing induction of labor were included. Each woman underwent sonographic studies before initiating IOL. The pregnancy outcome in those who developed NRFHR and those with reassuring FHR during labor were compared and correlated with baseline Doppler flow indices and method of induction.</p><p><strong>Results: </strong>Overall, 219 women were included, of whom 133 underwent IOL with prostaglandin E2 and 86 with a Foley catheter balloon. On multivariate logistic regression analysis, a lower MCA-PI percentile was associated with NRFHR in women that were induced with prostaglandin E2.</p><p><strong>Conclusion: </strong>A lower middle cerebral artery pulsatility index value might represent a lower placental reserve and, therefore, a higher risk of NRFHR monitoring during labor. This finding might assist in selecting the appropriate method of IOL.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preconception body mass index is associated with the risk of spontaneous preterm birth among women with gestational diabetes: A retrospective cohort study. 妊娠期糖尿病妇女的孕前体重指数与自发性早产风险相关:一项回顾性队列研究
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-12 DOI: 10.1002/ijgo.70056
Yuan Yuan, Shuting Yu
{"title":"Preconception body mass index is associated with the risk of spontaneous preterm birth among women with gestational diabetes: A retrospective cohort study.","authors":"Yuan Yuan, Shuting Yu","doi":"10.1002/ijgo.70056","DOIUrl":"https://doi.org/10.1002/ijgo.70056","url":null,"abstract":"<p><strong>Objective: </strong>Prior research efforts have not effectively clarified the relationship between preconception body mass index (BMI) and spontaneous preterm birth among women with gestational diabetes mellitus (GDM), particularly among Asian women. This study explores the relationship between pre-pregnancy BMI and spontaneous preterm birth among women with GDM, taking into account triacylglycerol (TG), glycated hemoglobin A1c (HbA1c), and gestational weight gain (GWG) levels.</p><p><strong>Method: </strong>Data from 1116 women with GDM who produced singleton live births were retrospectively analyzed. Logistic regression models were used to explore the relationship between pre-pregnancy BMI and spontaneous preterm birth.</p><p><strong>Results: </strong>Relative to women with GDM with a BMI in the normal range, those who were overweight/obese exhibited a significantly higher risk of spontaneous preterm birth. This link between BMI and spontaneous preterm birth risk varied as a function of GWG, HbA1c, and TG. Specifically, among those women who were overweight/obese prior to pregnancy, TG levels were significantly related to spontaneous preterm birth risk at TG concentrations exceeding 1.69 mmol/L. Notably, the combination of overweight/obese status, excessive GWG, and/or HbA1c levels ≥5.5% was associated with a higher risk of spontaneous preterm birth relative to overweight/obese status alone.</p><p><strong>Conclusion: </strong>These data show that preconception BMI is significantly linked to the risk of spontaneous preterm birth among Chinese GDM patients. When examining this relationship, HbA1c, TG, and GWG levels should be taken into consideration.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor: Postoperative pain control and opioid use with transversus abdominis plane block and scheduled multimodal pain management in patients undergoing cesarean section 致编辑的信:剖宫产患者术后疼痛控制和阿片类药物使用与腹横面阻滞和计划多模式疼痛管理。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-11 DOI: 10.1002/ijgo.70071
Ning Cong, Yan-Hua Guo, Fu-Shan Xue
{"title":"Letter to the Editor: Postoperative pain control and opioid use with transversus abdominis plane block and scheduled multimodal pain management in patients undergoing cesarean section","authors":"Ning Cong,&nbsp;Yan-Hua Guo,&nbsp;Fu-Shan Xue","doi":"10.1002/ijgo.70071","DOIUrl":"10.1002/ijgo.70071","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":"169 2","pages":"859-860"},"PeriodicalIF":2.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life and sexual health of women with peripartum hysterectomy: A single-center experience from South India. 围产期子宫切除术妇女的生活质量和性健康:来自南印度的单中心经验
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-11 DOI: 10.1002/ijgo.70058
Nivedita Jha, Pavani Manikya Palepu, Veena Pampapati, Moushumi P Mukherjee, Kayathri Karthikeyan, Manoharan Anuja, Kirti Girish Deodhare, Kumari Pannirselvan
{"title":"Quality of life and sexual health of women with peripartum hysterectomy: A single-center experience from South India.","authors":"Nivedita Jha, Pavani Manikya Palepu, Veena Pampapati, Moushumi P Mukherjee, Kayathri Karthikeyan, Manoharan Anuja, Kirti Girish Deodhare, Kumari Pannirselvan","doi":"10.1002/ijgo.70058","DOIUrl":"https://doi.org/10.1002/ijgo.70058","url":null,"abstract":"<p><strong>Objective: </strong>The quality of life and psychosomatic consequences of peripartum hysterectomy (PH) have not been studied in a larger cohort. Therefore, the present study aimed to evaluate the quality of life, social and sexual functions in women who underwent peripartum hysterectomy.</p><p><strong>Methods: </strong>In this retrospective cohort study, women who underwent PH from July 2016 to June 2021 were identified. Women who had a cesarean delivery (CD) in the same period were chosen as controls. The WHO quality of life (brief version) (WHOQOL-BREF), evaluation of social system (EVOS) scale, and Arizona sexual experience scale (ASEX) were utilized to assess quality of life, sexual satisfaction and social health.</p><p><strong>Results: </strong>A total of 75 women in PH and 75 in the CD group completed WHOQOL-BREF, while only 53 women completed ASEX and EVOS. The mean age was 29.13 ± 4.5 and 27.69 ± 4.38 years in the PH and CD group, respectively. General quality of life and health were significantly lower in the PH group (mean difference [95% CI], -27.16 [-33.80-20.54]; P = 0.000). No significant difference was observed in the physical (62.52 ± 14.9 vs. 64.52 ± 12.62; P = 0.376) and social domain (70.44 ± 15.33 vs. 70.77 ± 14.84; P = 0.893) of QOL. However, in the psychological (47.61 ± 11.76 vs. 54.77 ± 11.67; P = 0.000) and environmental domain (59.79 ± 8.61 vs. 65.29 ± 10.61; P = 0.001), significantly lower scores were observed in women with PH. The ASEX score was comparable (17.51 ± 5.83 vs. 17.8 ± 4.82; P = 0.745).</p><p><strong>Conclusion: </strong>The overall quality of life and psychological health are inferior in women who have had a peripartum hysterectomy. However, physical function and sexual satisfaction are comparable to those who had a cesarean delivery.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative pain after MiniLap percutaneous versus standard laparoscopic salpingo-oophorectomy: A propensity-matched study. MiniLap经皮输卵管卵巢切除术与标准腹腔镜输卵管卵巢切除术术后疼痛:一项倾向匹配的研究。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-11 DOI: 10.1002/ijgo.70060
Stefano Restaino, Federico Paparcura, Martina Arcieri, Alice Poli, Giulia Pellecchia, Giorgio Bogani, Cristina Taliento, Luigi Della Corte, Federica Perelli, Jvan Casarin, Salvatore Gueli Alletti, Tiziana Bove, Teresa Dogareschi, Lorenza Driul, Francesco Fanfani, Anna Fagotti, Giovanni Scambia, Giuseppe Vizzielli
{"title":"Postoperative pain after MiniLap percutaneous versus standard laparoscopic salpingo-oophorectomy: A propensity-matched study.","authors":"Stefano Restaino, Federico Paparcura, Martina Arcieri, Alice Poli, Giulia Pellecchia, Giorgio Bogani, Cristina Taliento, Luigi Della Corte, Federica Perelli, Jvan Casarin, Salvatore Gueli Alletti, Tiziana Bove, Teresa Dogareschi, Lorenza Driul, Francesco Fanfani, Anna Fagotti, Giovanni Scambia, Giuseppe Vizzielli","doi":"10.1002/ijgo.70060","DOIUrl":"https://doi.org/10.1002/ijgo.70060","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to compare postoperative outcomes in patients undergoing standard laparoscopic salpingo-oophorectomy versus those using the MiniLap percutaneous surgical system, aiming to demonstrate the non-inferiority of this ultra-minimally invasive surgical technique compared to the current gold standard.</p><p><strong>Methods: </strong>This was a retrospective, single-center propensity-matched case-control study. A total of 80 surgical patients undergoing salpingo-oophorectomy for benign pathology were selected, with 40 in each group (MiniLap in group A and S-LPS in group B). Postoperative pain was subjectively reported at 2, 4, 12, and 24 h after surgery. The secondary outcomes of this study were to evaluate differences in the duration of surgery, intraoperative blood loss, postoperative complications, and cosmetic results.</p><p><strong>Results: </strong>The median operative time was 57.7 min (range, 28-125) in group A and 75.5 min (range, 22-180) in group B (P value 0.005). No statistical differences were recorded in terms of estimated blood loss (P value 0.05), length of hospital stay (P value 0.74), complications (P-value 0.31), and postoperative pain (P value 0.06 at 2 h postoperatively). Cosmetic outcomes acquired through subjective assessment by the patient and surgeon at discharge and 1 month after surgery demonstrated a statistically significant higher satisfaction rate in the MiniLap compared to the S-LPS group.</p><p><strong>Conclusion: </strong>Our study demonstrates that salpingo-oophorectomy performed with the MiniLap system is feasible, safe, and well-tolerated by patients. Furthermore, this technique has proven to be non-inferior to standard LPS in terms of postoperative pain, blood loss, hospital stay duration, and complications.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143604826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Premature ovarian insufficiency, the unrecognized cause of sub-fertility in Africa. 早卵巢功能不全,在非洲生育能力低下的未被认识的原因。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-10 DOI: 10.1002/ijgo.70067
Bruno Bongo, Charles Muteshi
{"title":"Premature ovarian insufficiency, the unrecognized cause of sub-fertility in Africa.","authors":"Bruno Bongo, Charles Muteshi","doi":"10.1002/ijgo.70067","DOIUrl":"https://doi.org/10.1002/ijgo.70067","url":null,"abstract":"","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosing polycystic ovary syndrome at a tertiary level hospital in Latin America. 在拉丁美洲三级医院诊断多囊卵巢综合征。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-09 DOI: 10.1002/ijgo.70026
Julieth Alexandra Guzmán López, Oscar Eduardo Rivera Contreras, Fabián Manrique Hernández, Jenny Alison González Moreno, Herwing Caicedo León, Valentina Cáceres Valero, Andrea Juliana Sepúlveda Sanguino, Andrés Sebastián Torres, Janer Sepúlveda Agudelo
{"title":"Diagnosing polycystic ovary syndrome at a tertiary level hospital in Latin America.","authors":"Julieth Alexandra Guzmán López, Oscar Eduardo Rivera Contreras, Fabián Manrique Hernández, Jenny Alison González Moreno, Herwing Caicedo León, Valentina Cáceres Valero, Andrea Juliana Sepúlveda Sanguino, Andrés Sebastián Torres, Janer Sepúlveda Agudelo","doi":"10.1002/ijgo.70026","DOIUrl":"https://doi.org/10.1002/ijgo.70026","url":null,"abstract":"<p><p>Polycystic ovary syndrome (PCOS) is the most common neuroendocrine disorder in women of reproductive age. There is little consensus on the diagnosis of this syndrome, which affects both the number of cases that are diagnosed and the respective consequences. The aim of the present study was to evaluate the degree to which currently established criteria for diagnosing polycystic ovary syndrome are followed at a tertiary-level hospital in Colombia. Cross-sectional, observational, analytical study of patients diagnosed with PCOS between 2012 and 2019. A statistical analysis was performed based on information obtained from clinical histories, using frequencies and percentages for categorical variables and measures of central tendency for continuous variables. A total of 66 patients were included in the study, of which 69.69% (n = 46) sought medical care for abnormal uterine bleeding, 64.9% (n = 37) were found to be overweight or obese, 39.39% (n = 26) had clinical hyperandrogenism and 84.84% (n = 56) presented imaging findings compatible with polycystic ovaries. The ultrasound description was incomplete in the majority of cases. A Ferriman-Gallwey score was used to evaluate 7.57% (n = 5) of the patients, 53.03% (n = 35) were diagnosed without a complete or any exclusion of differential pathologies and 34.85% (n = 23) of the women were diagnosed with PCOS in accordance with currently established criteria. The main causes of the high frequency of diagnosing PCOS in a manner that did not accord with current criteria may have been not having excluded differential pathologies, not applying the established scale for objectively evaluating hirsutism and a lack of specifying follicular counts in imaging reports.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal predictors of ventriculoperitoneal shunt requirement and adverse perinatal outcomes in newborns with open spina bifida. 开放性脊柱裂新生儿脑室-腹膜分流需求和不良围产期结局的产前预测因素。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-07 DOI: 10.1002/ijgo.70063
Ezgi Başaran, Ecem Haliloğlu, Osman Onur Özkavak, Murat Haksever, Harun Demirci, Özgür Öcal, Atakan Tanaçan, Dilek Şahin
{"title":"Prenatal predictors of ventriculoperitoneal shunt requirement and adverse perinatal outcomes in newborns with open spina bifida.","authors":"Ezgi Başaran, Ecem Haliloğlu, Osman Onur Özkavak, Murat Haksever, Harun Demirci, Özgür Öcal, Atakan Tanaçan, Dilek Şahin","doi":"10.1002/ijgo.70063","DOIUrl":"https://doi.org/10.1002/ijgo.70063","url":null,"abstract":"<p><strong>Objective: </strong>Spina bifida is a group of anomalies that, while non-lethal, require careful prenatal evaluation and prognosis prediction due to their association with common motor and cognitive problems. In this study, we investigated the need for postnatal ventriculoperitoneal shunting (VPS) in fetuses with open spina bifida and explored the relationship between adverse perinatal outcomes and prenatal ultrasonographic findings.</p><p><strong>Methods: </strong>In this retrospective study, fetuses with open spina bifida that were diagnosed prenatally and resulted in a live birth were examined. The fetuses were divided into two groups: those who required VPS and those who did not require VPS in the postnatal period, and their prenatal clinical characteristics (lateral ventricle [LV] width, defect size, and defect level) and postnatal results (Apgar scores, length of hospital stay, lower extremity motor functions, bladder dysfunction, and epilepsy) were compared.</p><p><strong>Results: </strong>Prenatal LV width, defect size, presence of hindbrain herniation, and defect level were significantly different between the groups (all P < 0.05). Similarly, a significant difference was seen when comparing adverse neonatal outcomes; with worse outcomes observed in the group requiring VPS. It was observed that LV width, sac size and hindbrain herniation predicted the need for VPS in univariate analyses (P = 0.002, P = 0.013, P: 0.004, respectively). However, defect level had no predictive effect on VPS requirement.</p><p><strong>Conclusion: </strong>Larger prenatal LV width and sac size were associated with an increased need for postnatal VPS and were effective in predicting adverse perinatal outcomes. Utilizing this information in prenatal counseling and pregnancy management may prove beneficial.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stem cell theory: A new horizon for the treatment of endometriosis by targeting mesenchymal stem cell. 干细胞理论:靶向间充质干细胞治疗子宫内膜异位症的新视野。
IF 2.6 3区 医学
International Journal of Gynecology & Obstetrics Pub Date : 2025-03-07 DOI: 10.1002/ijgo.70046
Wanhui You, Siyu Wang, Chan Li, Yuting Ma, Fangyuan Liu, Ying Shen, Yingdong Wang, Fang Wan, Fengjuan Han
{"title":"Stem cell theory: A new horizon for the treatment of endometriosis by targeting mesenchymal stem cell.","authors":"Wanhui You, Siyu Wang, Chan Li, Yuting Ma, Fangyuan Liu, Ying Shen, Yingdong Wang, Fang Wan, Fengjuan Han","doi":"10.1002/ijgo.70046","DOIUrl":"https://doi.org/10.1002/ijgo.70046","url":null,"abstract":"<p><p>Endometriosis is a prevalent chronic gynecological disease that poses significant challenges for treatment due to its extensive lesions, diverse morphology, unknown etiology, and tendency for recurrence. In the early 21st century, the stem cell theory of endometriosis pathogenesis has offered new insights into its diagnosis and treatment. The stem cell theory posits that the terminal cells in the ectopic lesions are unable to sustain the long-term development of the lesions. Instead, endometrial stem cells (SCs) and SCs from outside the uterus are believed to participate in the formation and development of endometriosis. Notably, mesenchymal SCs (MSCs), which are multipotent SCs derived from the mesoderm, may contribute to the progression and potential malignant transformation of endometriosis through specific mechanisms. Therefore, this paper outlines the pathogenesis of endometriosis and the discovery of the stem cell theory. Additionally, it summarizes recent advancements in understanding the role of MSCs from various sources in endometriosis pathogenesis and proposes intervention strategies targeting MSCs for the treatment of endometriosis.</p>","PeriodicalId":14164,"journal":{"name":"International Journal of Gynecology & Obstetrics","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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