{"title":"Also long overdue: consideration of collider bias in guidelines and tools for systematic reviews and meta-analyses of observational studies.","authors":"Judith J M Rijnhart, Ava Rabbers, Santina Rizzuto","doi":"10.1093/ije/dyae147","DOIUrl":"https://doi.org/10.1093/ije/dyae147","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 6","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alison Fang-Wei Wu, Morag Henderson, Matt Brown, Tugba Adali, Richard J Silverwood, Darina Peycheva, Lisa Calderwood
{"title":"Cohort Profile: Next Steps-the longitudinal study of people in England born in 1989-90.","authors":"Alison Fang-Wei Wu, Morag Henderson, Matt Brown, Tugba Adali, Richard J Silverwood, Darina Peycheva, Lisa Calderwood","doi":"10.1093/ije/dyae152","DOIUrl":"10.1093/ije/dyae152","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 6","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11561396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rothman diagrams: the geometry of confounding and standardization.","authors":"Eben Kenah","doi":"10.1093/ije/dyae139","DOIUrl":"10.1093/ije/dyae139","url":null,"abstract":"<p><p>We outline a geometric perspective on causal inference in cohort studies that can help epidemiologists understand the role of standardization in controlling for confounding. For simplicity, we focus on a binary exposure X, a binary outcome D, and a binary confounder C that is not causally affected by X. Rothman diagrams plot the risk of disease in the unexposed on the x-axis and the risk in the exposed on the y-axis. The crude risks define a point in the unit square, and the stratum-specific risks at each level of C define two other points in the unit square. Standardization produces points along the line segment connecting the stratum-specific points. When there is confounding by C, the crude point is off this line segment. The set of all possible crude points is a rectangle with corners at the stratum-specific points and sides parallel to the axes. When there are more than two strata, standardization produces points in the convex hull of the stratum-specific points, and there is confounding if the crude point is outside this convex hull. We illustrate these ideas using data from a study in Newcastle, United Kingdom, in which the causal effect of smoking on 20-year mortality was confounded by age.</p>","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 6","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11565235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Mijanur Rahman, Joachim Worthington, Julia Steinberg, Michael David
{"title":"Using G-methods to assess and mitigate bias from coarsening time intervals in evaluating colorectal cancer screening efficiency.","authors":"Md Mijanur Rahman, Joachim Worthington, Julia Steinberg, Michael David","doi":"10.1093/ije/dyae159","DOIUrl":"https://doi.org/10.1093/ije/dyae159","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 6","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matthew N Ahmadi,Pieter Coenen,Leon Straker,Emmanuel Stamatakis
{"title":"Device-measured stationary behaviour and cardiovascular and orthostatic circulatory disease incidence.","authors":"Matthew N Ahmadi,Pieter Coenen,Leon Straker,Emmanuel Stamatakis","doi":"10.1093/ije/dyae136","DOIUrl":"https://doi.org/10.1093/ije/dyae136","url":null,"abstract":"BACKGROUNDPrevious studies have indicated that standing may be beneficially associated with surrogate metabolic markers, whereas more time spent sitting has an adverse association. Studies assessing the dose-response associations of standing, sitting and composite stationary behaviour time with cardiovascular disease (CVD) and orthostatic circulatory disease are scarce and show an unclear picture.OBJECTIVETo examine associations of daily sitting, standing and stationary time with CVD and orthostatic circulatory disease incidence.METHODSWe used accelerometer data from 83 013 adults (mean age ± standard deviation = 61.3 ± 7.8; female = 55.6%) from the UK Biobank to assess daily time spent sitting and standing. Major CVD was defined as coronary heart disease, heart failure and stroke. Orthostatic circulatory disease was defined as orthostatic hypotension, varicose vein, chronic venous insufficiency and venous ulcers. To estimate the dose-response hazard ratios (HR) we used Cox proportional hazards regression models and restricted cubic splines. The Fine-Gray subdistribution method was used to account for competing risks.RESULTSDuring 6.9 (±0.9) years of follow-up, 6829 CVD and 2042 orthostatic circulatory disease events occurred. When stationary time exceeded 12 h/day, orthostatic circulatory disease risk was higher by an average HR (95% confidence interval) of 0.22 (0.16, 0.29) per hour. Every additional hour above 10 h/day of sitting was associated with a 0.26 (0.18, 0.36) higher risk. Standing more than 2 h/day was associated with an 0.11 (0.05, 0.18) higher risk for every additional 30 min/day. For major CVD, when stationary time exceeded 12 h/day, risk was higher by an average of 0.13 (0.10, 0.16) per hour. Sitting time was associated with a 0.15 (0.11, 0.19) higher risk per extra hour. Time spent standing was not associated with major CVD risk.CONCLUSIONSTime spent standing was not associated with CVD risk but was associated with higher orthostatic circulatory disease risk. Time spent sitting above 10 h/day was associated with both higher orthostatic circulatory disease and major CVD risk. The deleterious associations of overall stationary time were primarily driven by sitting. Collectively, our findings indicate increasing standing time as a prescription may not lower major CVD risk and may lead to higher orthostatic circulatory disease risk.","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"74 1","pages":""},"PeriodicalIF":7.7,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142443769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacqueline Davis, Zenobia Talati, Sarah Whalan, Wesley Billingham, Nina D'Vaz, Lisa Gibson, Susan L Prescott, Desiree T Silva
{"title":"Cohort Profile: The ORIGINS pregnancy and birth cohort.","authors":"Jacqueline Davis, Zenobia Talati, Sarah Whalan, Wesley Billingham, Nina D'Vaz, Lisa Gibson, Susan L Prescott, Desiree T Silva","doi":"10.1093/ije/dyae146","DOIUrl":"10.1093/ije/dyae146","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 6","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11550191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wonjeong Jeong, Yoon A Kim, Soo Yeon Song, Dong-Hee Koh, Hyoung-Ryoul Kim, Jae-Lim Cho, Changsoo Kim, Jae Kwan Jun
{"title":"Cohort Profile: The Registry-based Epidemiological Study of Cancer in Fire Unit and Emergency Officers (RESCUE) cohort.","authors":"Wonjeong Jeong, Yoon A Kim, Soo Yeon Song, Dong-Hee Koh, Hyoung-Ryoul Kim, Jae-Lim Cho, Changsoo Kim, Jae Kwan Jun","doi":"10.1093/ije/dyae143","DOIUrl":"10.1093/ije/dyae143","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 6","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11512110/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142500021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Azar Mehrabadi,Nichole Austin,Katherine M Keyes,Mary A De Vera
{"title":"It's personal: navigating research questions that stem from our lived experiences.","authors":"Azar Mehrabadi,Nichole Austin,Katherine M Keyes,Mary A De Vera","doi":"10.1093/ije/dyae132","DOIUrl":"https://doi.org/10.1093/ije/dyae132","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"10 1","pages":""},"PeriodicalIF":7.7,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142436032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Mortality in women with a history of incarceration in Norway: a 20-year national cohort study.","authors":"","doi":"10.1093/ije/dyae155","DOIUrl":"https://doi.org/10.1093/ije/dyae155","url":null,"abstract":"","PeriodicalId":14147,"journal":{"name":"International journal of epidemiology","volume":"53 6","pages":""},"PeriodicalIF":6.4,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}