IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-18 DOI: 10.1002/cctc.71121

Jiayue Qu, Meihan Li, Keshuo Zheng, Jiacheng Huang, Junhong Chen, Zongyuan Xiao, Aihui Zhang, Wenjing Hong

{"title":"Harnessing Enzymatic Strategies for Chitosan Depolymerization: Mining, Mechanism, and Engineering","authors":"Jiayue Qu, Meihan Li, Keshuo Zheng, Jiacheng Huang, Junhong Chen, Zongyuan Xiao, Aihui Zhang, Wenjing Hong","doi":"10.1002/cctc.71121","DOIUrl":"https://doi.org/10.1002/cctc.71121","url":null,"abstract":"<div>\u0000 \u0000 Chitosan, a renewable marine polysaccharide derived from chitin, holds significant potential for conversion into high-value chitooligosaccharides with superior bioactivity and water solubility. However, the intrinsically poor solubility and low bioavailability of native chitosan severely limit its efficient utilization, necessitating the development of effective depolymerization strategies. This review comprehensively examines enzymatic depolymerization as a sustainable and efficient alternative to conventional chemical and physical methods, offering superior specificity, mild reaction conditions, and environmental compatibility. We begin with a critical comparison of these strategies to underscore the need for the development of biocatalytic approaches. Subsequently, we explore the diversity of chitosan-degrading enzymes across various glycosyl hydrolase families, detailing their catalytic mechanisms, cleavage specificities, and key structural domains governing substrate recognition and hydrolysis. The review further summarizes protein engineering strategies, including directed evolution, semi-rational design, and rational design, used to enhance chitosanase activity, thermostability, and product specificity. Finally, we discuss persistent challenges, such as the lack of crystal structures for certain enzyme families and the complexity of enzyme-substrate interactions. Future research will focus on resolving uncharacterized chitosanase structures, deepening mechanistic understanding of enzyme-substrate interactions, and integrating artificial intelligence with synthetic biology to develop robust biocatalysts tailored for industrial applications.\u0000 </div>","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":"18 20","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alkynylation of Formaldehyde With a Copper(I)–Acetylide Phenanthroline Catalyst 用铜(I) -乙酰基菲罗啉催化剂催化甲醛的炔化反应

IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-18 DOI: 10.1002/cctc.71106

Leo Saputra, Philipp D. Engel, Frank Rominger, Frank Bienewald, Grigory A. Shevchenko, Ansgar Schäfer, Peter Deglmann, Peter Comba, A. Stephen K. Hashmi, Thomas Schaub, Jaroslaw Mormul

引用次数: 0

Gallium-Regulated Cu+/Cu0 Mixed Valence and Oxygen-Deficient Sites in Core-Shell Cu2O for Selective CO2-to-C2+ Electrosynthesis 镓调控Cu+/Cu0在co_2 - c2 +电合成中的混合价和缺氧位点

IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-17 DOI: 10.1002/cctc.71122

Hao Li, Xuan Zhang, Yajuan Wei, Jingbo Zhang

{"title":"Gallium-Regulated Cu+/Cu0 Mixed Valence and Oxygen-Deficient Sites in Core-Shell Cu2O for Selective CO2-to-C2+ Electrosynthesis","authors":"Hao Li, Xuan Zhang, Yajuan Wei, Jingbo Zhang","doi":"10.1002/cctc.71122","DOIUrl":"https://doi.org/10.1002/cctc.71122","url":null,"abstract":"<div>\u0000 \u0000 Electrochemical CO2 reduction to multicarbon C2+ products requires efficient C─C coupling while maintaining catalytically favorable Cu states under strongly reducing conditions. Herein, Ga-modified core–shell Cu2O catalysts are constructed by a wet-chemical reduction method to couple Cu-valence regulation with oxygen-defect generation within a phase-preserved Cu2O framework. Ga incorporation retains the ca. 200 nm core–shell morphology but perturbs the local Cu─O environment, increases the Cu+/Cu0 ratio from 2.54 to 3.45, and raises the defect-associated O 1s contribution from 75.13% to 82.94%. In a flow cell containing 1.0 M KOH, the optimized Ga/Cu2O-II catalyst delivers a C2+ Faradaic efficiency of 73.5%, a C2+ partial current density of 251 mA cm−2, and an FEC2+/FEC1 ratio of 6.8 at −1.26 V versus RHE; the ethanol Faradaic efficiency reaches 37.9%. After 12 h electrolysis, the Cu+/Cu0 ratio remains 2.94 and FEC2+ remains above 60%. The combined structural, electrochemical, and post-reaction results support a dual-regulation picture in which a Cu+-rich Cu+/Cu0 surface favors carbon-intermediate retention and C─C coupling, while oxygen-deficient sites increase the population of accessible adsorption environments and facilitate conversion of oxygen-containing intermediates. This work demonstrates a simple strategy for stabilizing a catalytically productive mixed-valence/defect state of Cu2O for high-rate C2+ electrosynthesis.\u0000 </div>","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":"18 20","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electronic Structure Regulation of Bi-Modified ZnFe2O4/Biochar for Efficient Tetracycline Photodegradation 铋修饰ZnFe2O4/生物炭对四环素高效光降解的电子结构调控

IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-17 DOI: 10.1002/cctc.71116

Lingyan Yang, Bingyan Du, Jie Liu, Kuan Peng, Yelin Zeng, Yonghong Wang, Wensheng Liu, Guangjun Wang, Chan Chen, Yaohui Wu

{"title":"Electronic Structure Regulation of Bi-Modified ZnFe2O4/Biochar for Efficient Tetracycline Photodegradation","authors":"Lingyan Yang, Bingyan Du, Jie Liu, Kuan Peng, Yelin Zeng, Yonghong Wang, Wensheng Liu, Guangjun Wang, Chan Chen, Yaohui Wu","doi":"10.1002/cctc.71116","DOIUrl":"https://doi.org/10.1002/cctc.71116","url":null,"abstract":"<div>\u0000 \u0000 Developing high-performance and magnetically recoverable photocatalysts through rational structural engineering is an effective strategy for improving the photocatalytic degradation of antibiotic pollutants. In this work, a Bimodified ZnFe2O4/biochar composite (BBZ) was successfully synthesized via a facile hydrothermal method by combining magnetic ZnFe2O4 nanoparticles with biomassderived biochar. The optimized 0.09BBZ delivered the best adsorptionphotocatalytic performance for tetracycline (TC), with 87.3% removal within 180 min under visible light, 74.9% and 10.1% higher than pristine biochar and ZnFe2O4/biochar (BZ), respectively. Characterizations confirmed Bidoping and biochar synergistically improved physicochemical properties via widened visible-light absorption, narrowed bandgap, accelerated interfacial charge transfer and inhibited electronhole recombination, boosting photocatalytic activity. Moreover, BBZ possessed favorable magnetic recyclability and stability, retaining 75% TC removal after five cycles. This work demonstrates that the combined strategy of elemental modification and biochar coupling provides an effective route for regulating the electronic structure and photocatalytic properties of ZnFe2O4-based materials, offering a promising photocatalyst for the efficient removal of antibiotic contaminants from water.\u0000 </div>","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":"18 20","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ca2+-Templated Structural Water Network on Pt-Supported Dendritic Mesoporous Silica Nanospheres Promotes Non-Adiabatic Concerted Proton-Electron Transfer for Selective Oxidation of Isononyl Alcohol pt负载的树状介孔二氧化硅纳米球上Ca2+模板结构水网络促进非绝热协同质子-电子转移选择性氧化异戊醇

IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-17 DOI: 10.1002/cctc.71118

Bo Peng, Tong Chen, Qingsong Xue, Meng Ding, Junling Xing, Changjiu Xia, Peng Wu, Kun Zhang

{"title":"Ca2+-Templated Structural Water Network on Pt-Supported Dendritic Mesoporous Silica Nanospheres Promotes Non-Adiabatic Concerted Proton-Electron Transfer for Selective Oxidation of Isononyl Alcohol","authors":"Bo Peng, Tong Chen, Qingsong Xue, Meng Ding, Junling Xing, Changjiu Xia, Peng Wu, Kun Zhang","doi":"10.1002/cctc.71118","DOIUrl":"https://doi.org/10.1002/cctc.71118","url":null,"abstract":"<div>\u0000 \u0000 Selective oxidation of aliphatic alcohols is a pivotal yet challenging C─H activation reaction. While non-adiabatic concerted proton-electron transfer (CPET) theoretically accelerates kinetics, efficient base-free heterogeneous catalysts remain elusive. Herein, we report Pt-Ca2+/dendritic mesoporous silica nanosphere (DMSN) catalysts prepared via sequential Ca2+ impregnation and Pt immobilization. The optimized catalyst exhibited exceptional performance in the aqueous-phase oxidation of isononyl alcohol (3,5,5-trimethylhexanol), achieving 95.1% conversion and 99.7% selectivity (120°C, 24 h) toward isononanoic acid. Surface hydrophobization effectively suppressed Ca2+ leaching, enabling high activity retention over four catalytic cycles. Mechanistic investigations reveal that Ca2+ plays a dual role: providing alkaline sites for alcoholic hydroxyl group deprotonation while templating a structural water network within confined channels to facilitate non-adiabatic CPET during C─H activation—a function mirroring the pivotal role of Ca2+ within the Mn4CaO5 cluster of Photosystem II in facilitating water splitting.\u0000 </div>","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":"18 20","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development of Supramolecular Framework Catalyst Constructed by the Self-Assembly of Iron-Porphyrin Complexes Bearing Ar-ArF Interaction Sites for Photochemical CO2 Reduction 具有Ar-ArF相互作用位点的铁-卟啉配合物自组装构建的光化学CO2还原超分子框架催化剂的开发

IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-17 DOI: 10.1002/cctc.71120

Karin Uchida, Akira Yoneda, Kento Kosugi, Wenqing Huang, Ritsu Nagai, Maho Imai, Masaki Kitada, Jumpei Kawaguchi, Tetsuya Kambe, Mio Kondo, Shigeyuki Masaoka

{"title":"Development of Supramolecular Framework Catalyst Constructed by the Self-Assembly of Iron-Porphyrin Complexes Bearing Ar-ArF Interaction Sites for Photochemical CO2 Reduction","authors":"Karin Uchida, Akira Yoneda, Kento Kosugi, Wenqing Huang, Ritsu Nagai, Maho Imai, Masaki Kitada, Jumpei Kawaguchi, Tetsuya Kambe, Mio Kondo, Shigeyuki Masaoka","doi":"10.1002/cctc.71120","DOIUrl":"https://doi.org/10.1002/cctc.71120","url":null,"abstract":"The reduction of carbon dioxide (CO2) into value-added compounds is a promising strategy for addressing environmental and energy challenges. Molecule-based heterogeneous catalysts are attractive because they combine the structural tunability of molecule-based catalysts with the durability and recyclability of heterogeneous systems. Herein, we report the construction of a supramolecular framework catalyst via the self-assembly of iron-porphyrin complexes bearing arene-perfluoroarene (Ar-ArF) interaction sites. Single-crystal x-ray structural analysis revealed that the porphyrin complexes form one-dimensional (1D) columnar structures via intermolecular interactions between the interaction sites, which further organize into a porous crystalline framework stabilized by multiple noncovalent interactions. The resulting supramolecular framework ([Fe-TPEP]cryst) functions as a molecule-based heterogeneous catalyst for photochemical CO2 reduction, exhibiting high selectivity for carbon monoxide (CO) formation. Comparative studies using a nonporous material bearing iron-porphyrin-based catalytic centers demonstrate that [Fe-TPEP]cryst shows enhanced catalytic activity, indicating the importance of the porous structure for the efficient catalysis.","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":"18 20","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cctc.71120","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Direct Route for Upcycling Electronic Waste Into High-Performance Palladium Catalysts 一种将电子垃圾升级为高性能钯催化剂的直接途径

IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-17 DOI: 10.1002/cctc.71112

Michaël Martin Romo y Morales, Dmytro Nikolaievskyi, Noura Haidar, Elodie Biancarelli, Etienne Airiau, Jean-Luc Rousset, Laurence Burel, Franck Morfin, Helena Kaper, Damien Bourgeois

{"title":"A Direct Route for Upcycling Electronic Waste Into High-Performance Palladium Catalysts","authors":"Michaël Martin Romo y Morales, Dmytro Nikolaievskyi, Noura Haidar, Elodie Biancarelli, Etienne Airiau, Jean-Luc Rousset, Laurence Burel, Franck Morfin, Helena Kaper, Damien Bourgeois","doi":"10.1002/cctc.71112","DOIUrl":"https://doi.org/10.1002/cctc.71112","url":null,"abstract":"Conversion to a circular economy needs efficient methods to recover critical metals from electronic waste. Here, we demonstrate a two-step, purification-free process to transform palladium contained in waste multilayer ceramic capacitors (MLCCs) into highly active heterogeneous catalysts. After acid leaching, Pd(II) was selectively extracted (97%–100% yield) using di-n-octyl sulfide (DOS) or N,N,N′,N′-tetrahexylmalonamide (THMA), then directly impregnated onto γ-Al2O3. The resulting catalysts—containing residual Ag or Bi—showed activity at the level of a commercial reference (1 wt% Pd on γ-Al2O3) in methane oxidation (T50 = 325°C–327°C) and hindered olefin hydrogenation (quantitative conversion during the first cycle at 185°C/20 bar), suggesting reasonable tolerance to metallic impurities. Notably, DOS-extracted catalysts retained full activity despite sulfur content (0.5–0.6 wt%), while THMA-derived systems showed three times higher intrinsic activity than the reference catalyst at 350°C. HRTEM-EDS revealed well-dispersed Pd or Pd/Ag nanoparticles. This approach eliminates the need for complete Pd purification, offering a sustainable route to upcycle complex e-waste into value-added materials for industrial catalysis.","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":"18 20","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cctc.71112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Front Cover: Understanding of Changed Hydrogen Evolution Reaction Characteristics by Controlling Pt–WOx Interactions in Different Tungsten Oxide Phases 封面：通过控制不同氧化钨相中Pt-WOx相互作用改变析氢反应特征的理解

IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-17 DOI: 10.1002/cctc.71131

So Hui Jeong, Lee Seul Oh, Mi Yoo, Tae-Ho Kim, Hyung Ju Kim

引用次数: 0

Tracking Electron Flow in Aqueous Electrochemical Nitrogen Reduction to Ammonia on Ru(0001) Ru（0001）上电化学氮还原制氨的电子流跟踪

IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-11 DOI: 10.1002/cctc.71109

AbhayRam Balakrishnan, Hong-Wei Lin, Yu-Hsuan Chou, Wei-Kai Shao, Mu-Jeng Cheng

{"title":"Tracking Electron Flow in Aqueous Electrochemical Nitrogen Reduction to Ammonia on Ru(0001)","authors":"AbhayRam Balakrishnan, Hong-Wei Lin, Yu-Hsuan Chou, Wei-Kai Shao, Mu-Jeng Cheng","doi":"10.1002/cctc.71109","DOIUrl":"https://doi.org/10.1002/cctc.71109","url":null,"abstract":"<div>\u0000 \u0000 Global ammonia production is dominated by the energy-intensive Haber-Bosch process, motivating the development of sustainable electrochemical alternatives. While lithium- and calcium-mediated systems in organic solvents have relatively high yields, aqueous electrochemical nitrogen reduction (N2ER) remains inefficient. Density functional theory (DFT) studies have significantly advanced the understanding of N2ER in aqueous solution; however, most have focused on thermodynamic and/or kinetic analyses to elucidate reaction mechanisms, while orbital-level insights remain largely unexplored. Here, we combine DFT calculations with intrinsic bond orbital analysis to examine orbital evolution during 13 protonation steps of N2ER. This approach identifies the orbitals responsible for proton accommodation in each intermediate. We find that nine of the 13 steps involve nitrogen lone-pair orbitals. These results suggest that protonation kinetics in aqueous N2ER are strongly influenced by interactions between nitrogen lone pairs and the local solvation environment, including cations and hydrogen bonding. Moreover, surface modifications, which profoundly affect the reactivity of the metal–nitrogen σ bond but have a lesser influence on nitrogen lone-pair orbitals are not expected to have a direct impact on the protonation kinetics of N2ER. Thus, rational manipulation of the local electrochemical environment, rather than solely modifying the catalyst surface, may be essential for improving N2ER performance.\u0000 </div>","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":"18 19","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149205301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imine Reductase-Mediated Regio- and Stereoselective Reductive Amination of Diamines 亚胺还原酶介导的二胺的区域和立体选择性还原胺化

IF 4.1 3区化学

ChemCatChem Pub Date : 2026-10-11 DOI: 10.1002/cctc.71107

Arnau Rué Casamajo, Yuqi Yu, Lucian Pirvu, Christian Schnepel, Simon J. Charnock, Francesco Falcioni, Martin A. Hayes, Nicholas J. Turner

{"title":"Imine Reductase-Mediated Regio- and Stereoselective Reductive Amination of Diamines","authors":"Arnau Rué Casamajo, Yuqi Yu, Lucian Pirvu, Christian Schnepel, Simon J. Charnock, Francesco Falcioni, Martin A. Hayes, Nicholas J. Turner","doi":"10.1002/cctc.71107","DOIUrl":"https://doi.org/10.1002/cctc.71107","url":null,"abstract":"N-Substituted diamines are common motifs in pharmaceutical building blocks and APIs. Chemical approaches for the synthesis of mono-substituted diamines rely on the use of protecting groups to control regioselectivity and prevent the formation of dialkylated products, resulting in long synthetic routes and low atom economy. Here we show that imine reductases (IREDs) can be used as biocatalysts to synthesise monoalkylated products in a single step, exploiting the high regioselectivity of enzymatic reductive amination. We report the identification and application of metagenomic IREDs for the regioselective reductive amination of a broad panel of diamines with high substrates loadings. The use of racemic diamines resulted in both regio- and enantio-selective reductive amination via kinetic resolution. The applicability of IRED biocatalysts on a preparative scale has been explored by the synthesis of a precursor to the antihistamine drug tripelennamine displaying space-time yields (STY) up to 36 g l−1 d−1.","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":"18 19","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/cctc.71107","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149205300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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