International Journal of Food Sciences and Nutrition最新文献

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Effects of dietary factors on hyperuricaemia and gout: a systematic review and meta-analysis of observational studies. 饮食因素对高尿酸血症和痛风的影响:观察性研究的系统回顾和荟萃分析。
IF 3.9 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-17 DOI: 10.1080/09637486.2024.2400489
Xi Chi,Yangyang Cen,Bowen Yang,Huanzhen Zhang,Zhiyu Pu,Jing Feng,Hongzhi Pan,Yannan Zhang
{"title":"Effects of dietary factors on hyperuricaemia and gout: a systematic review and meta-analysis of observational studies.","authors":"Xi Chi,Yangyang Cen,Bowen Yang,Huanzhen Zhang,Zhiyu Pu,Jing Feng,Hongzhi Pan,Yannan Zhang","doi":"10.1080/09637486.2024.2400489","DOIUrl":"https://doi.org/10.1080/09637486.2024.2400489","url":null,"abstract":"This study aimed to gather the best evidence on the relationship between dietary factors and hyperuricaemia and gout. We searched databases including PubMed, Embase, Cochrane, and Web of Science from database creation to July 2023. Meta-analysis showed that consumption of alcohol (OR: 1.41, 95% CI: 1.29-1.55; 1.60, 95% CI: 1.33-1.93, respectively), red meat (OR:1.27, 95% CI: 1.18-1.37; 1.32, 95% CI: 1.18-1.47, respectively), fructose (OR: 1.29, 95% CI: 1.21-1.38; 1.65, 95% CI: 1.36-2.01, respectively) and seafoods (OR: 1.40, 95% CI: 1.20-1.64; 1.29, 95% CI: 1.00-1.67, respectively) were positively associated with the risk of hyperuricaemia and gout, while vegetables (OR: 0.78, 95% CI: 0.71-0.85; 0.96,95% CI 0.74-1.24, respectively) were inversely associated. Dairy products (OR: 0.69, 95% CI: 0.61-0.78) and nuts (OR: 0.75, 95% CI: 0.60-0.93) were also inversely associated with the risk of hyperuricaemia. Soy products (OR: 0.86, 95% CI: 0.75-0.98) and coffee (OR: 0.56, 95% CI: 0.39-0.81) were negatively associated with the risk of gout.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":"190 1","pages":"1-21"},"PeriodicalIF":3.9,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oat anthranilamides regulates high-fat diet-induced intestinal inflammation by the TLR4/NF-κb signalling pathway and gut microbiota 燕麦蒽酰胺通过TLR4/NF-κb信号通路和肠道微生物群调节高脂饮食诱发的肠道炎症
IF 3.9 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-16 DOI: 10.1080/09637486.2024.2401130
Yongyong Liu, Kai Huang, Yu Zhang, Sen Li, Hongdong Song, Xiao Guan
{"title":"Oat anthranilamides regulates high-fat diet-induced intestinal inflammation by the TLR4/NF-κb signalling pathway and gut microbiota","authors":"Yongyong Liu, Kai Huang, Yu Zhang, Sen Li, Hongdong Song, Xiao Guan","doi":"10.1080/09637486.2024.2401130","DOIUrl":"https://doi.org/10.1080/09637486.2024.2401130","url":null,"abstract":"Oat anthranilamides have demonstrated antioxidant and anti-inflammatory effects; however, the precise mechanism of action remains unclear. This study investigated the impact of oat anthranilamide B...","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":"36 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142247522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbially mediated phenolic catabolites exert differential genoprotective activities in normal and adenocarcinoma cell lines. 微生物介导的酚类代谢产物在正常细胞系和腺癌细胞系中发挥不同的基因保护活性。
IF 3.9 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-11 DOI: 10.1080/09637486.2024.2397055
Brian Óg Murphy,Cheryl Latimer,Sara Dobani,L Kirsty Pourshahidi,Massimilano Fontana,Nigel G Ternan,Gordon McDougall,Ian Rowland,Gema Pereira-Caro,Kieran M Tuohy,Daniele Del Rio,Tahani M Almutairi,Alan Crozier,Nenad Naumovski,Chris I R Gill
{"title":"Microbially mediated phenolic catabolites exert differential genoprotective activities in normal and adenocarcinoma cell lines.","authors":"Brian Óg Murphy,Cheryl Latimer,Sara Dobani,L Kirsty Pourshahidi,Massimilano Fontana,Nigel G Ternan,Gordon McDougall,Ian Rowland,Gema Pereira-Caro,Kieran M Tuohy,Daniele Del Rio,Tahani M Almutairi,Alan Crozier,Nenad Naumovski,Chris I R Gill","doi":"10.1080/09637486.2024.2397055","DOIUrl":"https://doi.org/10.1080/09637486.2024.2397055","url":null,"abstract":"Age-associated decline of nuclear factor erythroid 2-related factor 2 (Nrf2) activity and DNA repair efficiency leads to the accumulation of DNA damage and increased risk of cancer. Understanding the mechanisms behind increased levels of damaged DNA is crucial for developing interventions to mitigate age-related cancer risk. Associated with various health benefits, (poly)phenols and their microbially mediated phenolic catabolites represent a potential means to reduce DNA damage. Four colonic-microbiota-derived phenolic catabolites were investigated for their ability to reduce H2O2-induced oxidative DNA damage and modulate the Nrf2-Antixoidant Response Element (ARE) pathway, in normal (CCD 841 CoN) and adenocarcinoma (HT29) colonocyte cell lines. Each catabolite demonstrated significant (p < .001) genoprotective activity and modulation of key genes in the Nrf2-ARE pathway. Overall, the colon-derived phenolic metabolites, when assessed at physiologically relevant concentrations, reduced DNA damage in both normal and adenocarcinoma colonic cells in response to oxidative challenge, mediated in part via upregulation of the Nrf2-ARE pathway.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":"24 1","pages":"1-14"},"PeriodicalIF":3.9,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional value of cereal-based gluten-free products and comparison to that of gluten containing counterparts in the Greek market. 谷物类无麸质产品的营养价值以及与希腊市场上含麸质同类产品的营养价值比较。
IF 3.9 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-09 DOI: 10.1080/09637486.2024.2397057
Eirini Bathrellou,Meropi D Kontogianni
{"title":"Nutritional value of cereal-based gluten-free products and comparison to that of gluten containing counterparts in the Greek market.","authors":"Eirini Bathrellou,Meropi D Kontogianni","doi":"10.1080/09637486.2024.2397057","DOIUrl":"https://doi.org/10.1080/09637486.2024.2397057","url":null,"abstract":"Nutritional value of the Gluten-free products (GFPs) has been highly debated. Aiming to assess the nutritional value of the cereal-based GFPs in the Greek market, information from the nutritional label and the ingredients list, of all GFPs and their gluten-containing (GC) counterparts available in a supermarket offering the greatest availability in the capital of Greece, were recorded. The sample consisted of 913 products: 351 GFPs and 562 GCPs, classified into 12 categories (e.g., breads, melbas, breakfast cereals, cereal bars, pasta, flours, cookies). With minor exceptions, comparisons among all food categories regarding nutrient profile and nutritional claims showed mixed results, though supporting an overly comparable nutritional profile of the GFPs. Still, a quarter of all GFPs presented an unhealthy nutritional profile. The findings of the present study are highly in agreement with those of relevant studies in the literature, that do not support an inferior nutritional profile compared to GC counterparts.","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":"23 1","pages":"1-9"},"PeriodicalIF":3.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of rhamnose consumption on bone mineral density in healthy postmenopausal women: a randomised, placebo-controlled, double-blind, parallel-group pilot study. 食用鼠李糖对绝经后健康女性骨矿物质密度的影响:一项随机、安慰剂对照、双盲、平行组试验研究。
IF 3.9 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-09 DOI: 10.1080/09637486.2024.2397056
Naoko Suzuki,Takafumi Imada,Naoki Ueshima,Hideyuki Orikoshi,Tsuyoshi Takara
{"title":"Effects of rhamnose consumption on bone mineral density in healthy postmenopausal women: a randomised, placebo-controlled, double-blind, parallel-group pilot study.","authors":"Naoko Suzuki,Takafumi Imada,Naoki Ueshima,Hideyuki Orikoshi,Tsuyoshi Takara","doi":"10.1080/09637486.2024.2397056","DOIUrl":"https://doi.org/10.1080/09637486.2024.2397056","url":null,"abstract":"Preventing the decrease in bone mineral density (BMD) is significant for postmenopausal women. We previously discovered that rhamnose, a deoxy monosaccharide used as a food additive, could suppress bone resorption; however, studies confirming this effect in postmenopausal women are lacking. Therefore, this pilot study aimed to explore whether rhamnose could help maintain BMD via bone resorption suppression in postmenopausal women. The participants consumed either 1.0 or 0.5 g/day of rhamnose or placebo for 24 weeks, and BMD (lumbar spine and femur) and bone turnover markers were measured. After 24 weeks, the group consuming rhamnose 1.0 g/day exhibited a significantly higher BMD of the lumbar spine than the placebo group. Furthermore, the levels of tartrate-resistant acid phosphatase 5b, a bone resorption marker, were significantly lower in both rhamnose groups. These results indicated that rhamnose might contribute to the maintenance of BMD by suppressing bone resorption in healthy postmenopausal women (UMIN000046570).","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":"23 1","pages":"1-12"},"PeriodicalIF":3.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142187192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of the food inflation impact on consumer behavior scale: a comparative measurement instrument with focus on food security. 验证食品通胀对消费者行为的影响量表:以食品安全为重点的比较测量工具。
IF 3.5 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-01 Epub Date: 2024-07-16 DOI: 10.1080/09637486.2024.2379819
Mehmet Haydaroğlu, Pelin Bilgiç
{"title":"Validation of the food inflation impact on consumer behavior scale: a comparative measurement instrument with focus on food security.","authors":"Mehmet Haydaroğlu, Pelin Bilgiç","doi":"10.1080/09637486.2024.2379819","DOIUrl":"10.1080/09637486.2024.2379819","url":null,"abstract":"<p><p>This study aimed to compare the change in consumer behaviour in the face of high inflation with respect to food security in the Turkish population by developing a 3-factor The Impact of Food Inflation on Consumer Behaviour (IFI-ConB) scale. Item generation and expert evaluation, item purification by preliminary application, and final administration were conducted. The moderate to severe food insecure individuals exhibited a higher inflation impact score on food consumption patterns, food shopping behaviours, and food purchasing motives factors compared to secure to mild insecure individuals. A positive correlation was found between the inflation impact score by IFI-ConB and the price motive for food choice. The primary food choice motive was health among the secure to mild insecure individuals, while for the moderate to severe food insecure individuals, it was price. The findings indicate that food insecure individuals are more affected by high food inflation compared to food secure individuals.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"597-608"},"PeriodicalIF":3.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141626656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dietary glycemic index and glycemic load predict longitudinal change in glycemic and cardio-metabolic biomarkers among old diabetic adults living in a resource-poor country. 膳食血糖指数和血糖负荷可预测生活在资源贫乏国家的老年糖尿病患者血糖和心血管代谢生物标志物的纵向变化。
IF 3.5 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-01 Epub Date: 2024-07-01 DOI: 10.1080/09637486.2024.2368843
Yen Nhi Hoang, Trong Hung Nguyen, Dang Khanh Ngan Ho, Chyi-Huey Bai, Wen-Ling Lin, Huong Duong Phan, Hoang Hiep Phan, Ngoc Luong Tran, Jung-Su Chang
{"title":"Dietary glycemic index and glycemic load predict longitudinal change in glycemic and cardio-metabolic biomarkers among old diabetic adults living in a resource-poor country.","authors":"Yen Nhi Hoang, Trong Hung Nguyen, Dang Khanh Ngan Ho, Chyi-Huey Bai, Wen-Ling Lin, Huong Duong Phan, Hoang Hiep Phan, Ngoc Luong Tran, Jung-Su Chang","doi":"10.1080/09637486.2024.2368843","DOIUrl":"10.1080/09637486.2024.2368843","url":null,"abstract":"<p><p>This study aims to investigate longitudinal associations between the dietary glycemic index (GI) and glycemic load (GL) and changes in glycemic and cardio-metabolic outcomes. A 28-month retrospective cohort study included 110 Vietnamese diabetic patients, collecting their dietary GI and GL values along with blood biochemical data from baseline 24-h dietary recall and medical records. Latent class growth modelling identified three distinct HbA1c trajectories during the follow-up period, with 51% of patients achieving good glycemic control. The adjusted linear mixed-effect model showed that 1 unit increase in logarithms in dietary GL was associated with a 0.14% increase in the log-HbA1c. Among poorly controlled diabetic patients, baseline GL values were positively correlated with increases in HbA1c; GI showed effects on changes in fasting plasma glucose and the triglyceride-glucose (TyG) index. No significant association was observed in patients with good glycemic control.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"550-561"},"PeriodicalIF":3.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141467906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weight, habitual fibre intake, and microbiome composition predict tolerance to fructan supplementation. 体重、习惯性纤维摄入量和微生物组组成可预测对果糖补充剂的耐受性。
IF 3.3 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-01 Epub Date: 2024-07-09 DOI: 10.1080/09637486.2024.2372590
Jeffrey Letourneau, Benjamin C Neubert, Diana Dayal, Verónica M Carrion, Heather K Durand, Eric P Dallow, Sharon Jiang, Michelle Kirtley, Geoffrey S Ginsburg, P Murali Doraiswamy, Lawrence A David
{"title":"Weight, habitual fibre intake, and microbiome composition predict tolerance to fructan supplementation.","authors":"Jeffrey Letourneau, Benjamin C Neubert, Diana Dayal, Verónica M Carrion, Heather K Durand, Eric P Dallow, Sharon Jiang, Michelle Kirtley, Geoffrey S Ginsburg, P Murali Doraiswamy, Lawrence A David","doi":"10.1080/09637486.2024.2372590","DOIUrl":"10.1080/09637486.2024.2372590","url":null,"abstract":"<p><p>Fructans are commonly used as dietary fibre supplements for their ability to promote the growth of beneficial gut microbes. However, fructan consumption has been associated with various dosage-dependent side effects. We characterised side effects in an exploratory analysis of a randomised trial in healthy adults (<i>n</i> = 40) who consumed 18 g/day inulin or placebo. We found that individuals weighing more or habitually consuming higher fibre exhibited the best tolerance. Furthermore, we identified associations between gut microbiome composition and host tolerance. Specifically, higher levels of <i>Christensenellaceae R-7 group</i> were associated with gastrointestinal discomfort, and a machine-learning-based approach successfully predicted high levels of flatulence, with <i>[Ruminococcus] torques group</i> and (<i>Oscillospiraceae</i>) <i>UCG-002 sp.</i> identified as key predictive taxa. These data reveal trends that can help guide personalised recommendations for initial inulin dosage. Our results support prior ecological findings indicating that fibre supplementation has the greatest impact on individuals whose baseline fibre intake is lowest.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"571-581"},"PeriodicalIF":3.3,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11491164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141563372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal fat intake in pregnancy and risk of depressive symptoms in Japanese adolescents: the Kyushu Okinawa Maternal and Child Health Study. 母亲孕期脂肪摄入量与日本青少年出现抑郁症状的风险:九州冲绳母婴健康研究。
IF 3.5 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-01 Epub Date: 2024-06-26 DOI: 10.1080/09637486.2024.2370351
Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Masashi Arakawa
{"title":"Maternal fat intake in pregnancy and risk of depressive symptoms in Japanese adolescents: the Kyushu Okinawa Maternal and Child Health Study.","authors":"Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Masashi Arakawa","doi":"10.1080/09637486.2024.2370351","DOIUrl":"10.1080/09637486.2024.2370351","url":null,"abstract":"<p><p>The current prebirth cohort study investigated the association between maternal intake of specific types of fatty acids during pregnancy and adolescent depressive symptoms based on the Center for Epidemiologic Studies Depression Scale. Subjects were 873 mother-child pairs. Dietary intake during the preceding month was assessed using a self-administered diet history questionnaire. The risk of depressive symptoms was 23.3% among the 873 adolescents at 13 years of age. Higher maternal saturated fatty acid intake during pregnancy was independently associated with a reduced risk of depressive symptoms in adolescents. Maternal intake of total fat, monounsaturated fatty acids, n-3 polyunsaturated fatty acids, α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, n-6 polyunsaturated fatty acids, linoleic acid, arachidonic acid and cholesterol during pregnancy was not significantly related to depressive symptoms in adolescents. Higher maternal intake of saturated fatty acids during pregnancy may be inversely associated with adolescent depressive symptoms.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"562-570"},"PeriodicalIF":3.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141456645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causal benefits of 25 dietary intakes on epigenetic ageing: a Mendelian randomisation study. 25 种膳食摄入量对表观遗传老化的因果效益:孟德尔随机研究。
IF 3.5 2区 农林科学
International Journal of Food Sciences and Nutrition Pub Date : 2024-09-01 Epub Date: 2024-07-17 DOI: 10.1080/09637486.2024.2379817
Kaixi Ding, Wei Jiang, Shangjing Wuke, Ming Lei
{"title":"Causal benefits of 25 dietary intakes on epigenetic ageing: a Mendelian randomisation study.","authors":"Kaixi Ding, Wei Jiang, Shangjing Wuke, Ming Lei","doi":"10.1080/09637486.2024.2379817","DOIUrl":"10.1080/09637486.2024.2379817","url":null,"abstract":"<p><p>DNA methylation GrimAge acceleration (DMGA) and intrinsic epigenetic age acceleration (IEAA) are important physiological markers for assessing the ageing process. Evidence from cross-sectional studies suggests that some dietary intake is associated with DMGA and IEAA. However, the causal relationship between them has yet to be elucidated. This Mendelian randomisation study uses genetic variants associated with different dietary intakes as instrumental variables to explore the causal benefits of multiple dietary intakes on DMGA and IEAA. Cheese intake, dark chocolate intake, average weekly red wine intake, dried fruit intake, fresh fruit intake, porridge intake, cereal intake, and liver intake had a negative causal association with DMGA, and poultry intake and doughnut intake had a positive causal association with DMGA (<i>p</i> < 0.05). Muesli and bran cereal intake had a negative causal association with IEAA, and pineapple intake had a positive causal association with IEAA (<i>p</i> < 0.05). Dietary intake positively causally associated with IEAA or DMGA may have accelerated biological ageing; conversely, dietary intake negatively causally associated with IEAA or DMGA may have contributed to delaying biological ageing. Based on genetic evidence, this study demonstrated some significant causal benefits of dietary intake on DMGA and IEAA, suggesting the possibility of intervening in DNA methylation acceleration and epigenetic age acceleration by adjusting these food intakes, thereby promoting health and delaying ageing. However, the findings of this study are exploratory and preliminary and need to be supported and validated by evidence from further clinical studies and mechanistic studies.</p>","PeriodicalId":14087,"journal":{"name":"International Journal of Food Sciences and Nutrition","volume":" ","pages":"582-596"},"PeriodicalIF":3.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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